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Efek Suplementasi Probiotik Oral Sebagai Terapi Tambahan pada Pasien Dermatitis Atopik Nailatul Fadhila; Gardenia Akhyar; Fory Fortuna; Ennesta Asri; Endrinaldi Endrinaldi; Yusticia Katar
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 2 (2023): Juni 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i2.849

Abstract

Latar Belakang: Dermatitis atopik merupakan peradangan kulit yang menjadi beban penyakit non-fatal dalam dermatologi. Etiologinya belum diketahui secara pasti. Probiotik merupakan bakteri baik yang memiliki potensial untuk menjadi terapi tambahan dermatitis atopik. Objektif: Kajian literatur sistematis ini dilakukan untuk mengetahui efek dari suplementasi probiotik oral sebagai terapi tambahan pada pasien dermatitis atopik. Metode: Studi literatur ini merupakan kajian literature sistematis. Pencarian literatur dilakukan di tiga pangkalan data, yaitu Pubmed, Proquest, dan The Cochrane Central Register of Controlled Trials (CENTRAL). Hasil: Terdapat sebelas studi yang dimasukkan dalam kajian literature sistematis ini dengan 918 kasus dermatitis atopik. Kesimpulan: Probiotik memberikan efek terapi berupa penurunan indeks SCORAD dan meningkatkan kualitas hidup pasien. serta dapat dijadikan sebagai opsi terapi tambahan pada pasien dermatitis atopik
Hubungan Kualitas Tidur dengan Derajat Keparahan Akne Vulgaris pada Siswa Kelas XII di SMAN 2 Bukittinggi Irma Yulianti; Ennesta Asri; Nuzulia Irawati
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 3 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i3.1076

Abstract

Latar Belakang: Akne vulgaris adalah suatu penyakit peradangan menahun pada folikel pilosebasea yang umumnya terjadi pada masa remaja, dapat sembuh sendiri dan menjadi tanda pertama pubertas. Kualitas tidur yang buruk dapat memicu peningkatan hormon androgen sehingga meningkatkan proliferasi keratin dan produksi sebum yang menjadi salah satu faktor penyebab terjadinya akne vulgaris. Objektif: Mengetahui hubungan kualitas tidur dengan derajat keparahan akne vulgaris pada siswa kelas XII. Metode: Penelitian ini merupakan penelitian analitik observasional dengan menggunakan desain cross sectional. Penelitian ini dilakukan di SMAN 2 Bukittinggi dengan menjadikan seluruh populasi menjadi sampel. Dalam penelitian ini 144 responden yang memenuhi kriteria. Instrumen yang digunakan berupa kuesioner PSQI (Pittsburgh Sleep Quality Index) untuk mengukur kualitas tidur, kemudian dianalisis menggunakan uji chi-square. Hasil: Hasil dari penelitian ini adalah 23 orang responden memiliki kualitas tidur yang baik, 17,4% diantaranya menderita akne vulgaris derajat ringan, 73,9% menderita akne vulgaris derajat sedang dan 8,7% menderita derajat berat, sedangkan pada 121 orang responden memiliki kualitas tidur yang buruk, 3,3% diantaranya menderita akne vulgaris derajat ringan, 68,6% menderita akne vulgaris derajat sedang dan 28,1% menderita akne vulgaris derajat berat. Hasil analisis data diperoleh p-value sebesar 0,007. Kesimpulan: Kesimpulan dari penelitian ini adalah terdapat hubungan yang bermakna antara kualitas tidur dengan derajat keparahan akne vulgaris pada siswa kelas XII di SMAN 2 Bukittinggi.
Performing Ocular Examinations as A Component of Self-Care For Individuals with Leprosy with The Aim of Eradicating Social Stigma and Prejudice Hendriati Hendriati; Tutty Ariani; Havriza Vitresia; Kemala Sayuti; Andrini Ariesti; Julita Julita; Qaira Anum; Satya Wydya Yenny; Rina Gustia; Gardenia Akhyar; Ennesta Asri; Indah Indria Sari; Astria Rima Rara Yuswir; Novian Novian; Rizki Dwayana; Agustin Vira; Rika Desviorita; Rendra Darma Satria
Warta Pengabdian Andalas Vol 31 No 3 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.3.537-546.2024

Abstract

Leprosy is still a health problem in several countries, including Indonesia. Disability due to leprosy is a health threat for sufferers and causes quality-of-life problems that can disrupt the productivity of leprosy patients. Ocular involvement in leprosy is joint, but little data has been reported. Apart from multi-drug treatment (MDT), leprosy sufferers must also be able to carry out continuous self-care to prevent further disability. This is a collaborative activity between the Department of Ophthalmology and Dermatology Venereology of the Faculty of Medicine, the University of Andalas in Puskesmas Pauh Kamba district of Padang Pariaman. This is an advocacy activity on self-care (3M: Seeing, Examining, and Protecting) and eye examination. The activity was followed by interactive discussions and continued with a direct examination for skin abnormalities and disabilities, eye examination, and fundoscope. The activity results were obtained from 24 respondents, 11 men and 13 women. The age range is 16-59 years (67%), with the highest level of education being Elementry School graduates, which is 11 people (46%). In the self-care questionnaire of patients, 40% behaved well, and the results of eye examinations almost suffered from dry eye complaints without disabilities.
Effect of Peer Education on Knowledge and Attitudes Toward Menstrual Hygiene Management Among Boarding School Students Besty Berliana; Defrin Defrin; Adrial Adrial; Yusrawati Yusrawati; Rozi Sastra Purna; Ennesta Asri
Jurnal Promosi Kesehatan Indonesia Vol 21 No 1: January 2026
Publisher : Master Program of Health Promotion Faculty of Public Health Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpki.21.1.35-47

Abstract

Background: More than half of adolescents in low- and middle-income countries feel unprepared for menarche due to a lack of menstrual knowledge, which leads to poor menstrual hygiene practices that increase reproductive health risks. This problem worsens in boarding schools, where restrictions like bans on mobile phones, limited contact with parents, and the absence of formal health programs severely limit access to accurate menstrual health information. Peer education leverages adolescents' natural dependence on peers for sensitive issues and is especially vital in environments with limited information, such as boarding schools. This study aimed to evaluate the effectiveness of peer education in enhancing Menstrual Hygiene Management (MHM) knowledge and attitudes among female students in a boarding school and to explore their experiences with this intervention.Method: An explanatory sequential mixed-methods design was employed. The quantitative phase involved a One Group Pre-test Post-test design with 31 purposively selected students to assess changes in knowledge and attitude following the peer education intervention. Five trained peer educators conducted 120-minute sessions using standardized modules. Quantitative data were analyzed using paired t-tests and N-gain scores. The qualitative phase adopted a phenomenological approach with in-depth interviews involving six primary informants (students) and five supporting informants (peer educators) to explore the intervention experiences and the mechanisms behind observed changes. Qualitative data were analyzed thematically with source triangulation to enhance credibility.Result: Mean knowledge scores increased significantly from 30.10 to 72.04 (p<0.001, N-gain=0.612, moderate effectiveness), with the largest improvement in pad disposal knowledge (90.3 percentage points). Mean attitude scores rose from 54.41 to 80.72 (p<0.001, N-gain=0.586, moderate effectiveness). Qualitative findings showed that students gained evidence-based knowledge, corrected menstrual myths, and expressed readiness to adopt proper hygiene practices. However, deeply rooted cultural beliefs remained resistant after a single session. The findings confirmed that knowledge improvements do not automatically lead to uniform behavioral change. Boarding schools should implement multiple-session peer education programs with spaced repetition, invest in peer educator training, establish student-led health clubs, and incorporate a formal MHM curriculum before menarche. 
EVALUASI PAPARAN SENYAWA TERFLUORINASI MELALUI PENGGUNAAN KOSMETIK BIBIR WATERPROOF PADA PEREMPUAN USIA SUBUR Muhammad Nur Alif Johar; Cimi Ilmiawati; Ennesta Asri
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 6 (2026): SINERGI : Jurnal Riset Ilmiah, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i6.2688

Abstract

Waterproof lip cosmetic is a popular innovation due to their long-lasting feature. Research indicates waterproof feature often rely on the addition of fluorinated compounds, substances known as carcinogenic to human and can persist in human. This study aims to evaluate exposure to fluorinated compounds through waterproof lip cosmetics usage among women of childbearing age. Utilizing a quantitative descriptive approach with a cross-sectional design, an online survey was conducted from October to December 2023. The study comprised 334 women of childbearing age, including 101 high school students, 127 university students, and 106 bank employees distributed across West Sumatra, Riau, and West Java using consecutive sampling. Data were gathered through a validated multilevel questionnaire covering demographic profiles, product usage frequency, and specific brands. The research shows that majority of respondents use waterproof lip cosmetics (82.3%), with liquid lipstick as the most prevalent product type (75.8%). Most respondents reported using products 1–5 times per week or more. Product composition analysis indicated that coloring agents were the most frequently components as a potential source of fluorinated compound exposure. Based on the survey and compositional analysis, this study concludes that waterproof lip cosmetics represent a potential source of exposure to fluorinated compounds.
Profile of Trichoepithelioma Patients at Hospital for the Period of 2016-2021 Fauziah Hannum; Ennesta Asri; Muhammad Zulfadli Syahrul
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.3802

Abstract

Trichoepithelioma is a rare benign tumor of the skin adnexa, of the pilosebaceous unit, especially of the hair follicle. This tumor is characterized by the appearance of lesions in the form of papules or nodules that are the color of the skin, with a size of 2-8 mm which can have solitary or multiple distribution. Trichoepithelioma has a psychosocial impact for sufferers, because trichoepithelioma lesions are often found on the face so that many sufferers feel embarrassed. This study is a retrospective descriptive study with a cross-sectional design that aims to determine the profile of trichoepithelioma based on age, gender, clinical picture, predilection site, duration before therapy, histopathological examination, treatment modality, and recurrence after therapy. From the 15 samples studied, it was found that the age group 11-19 years was the age group with the most trichoepithelioma patients (66.7%) with the highest gender being female (66.7%). All patients had clinical features of multiple trichoepithelioma (100%) with the greatest predilection for the nose (34.1%). Most of the patients had the same family history as the patient (66.7%). The duration of most patients 6 years (53.3%). Most of the patients did not perform histopathological examination (53.3%). The modality of therapy given to all patients was electrocautery with curettage (100%). Most of the patients did not follow up again regarding their recurrence (60%). Meanwhile, the most patients who did follow-up related to recurrence were &lt;1 year (33.3%).
Profile of Characteristics, Severity, Location, Lesion Size, and Stress Levels in Patients with Lichen Simplex Chronicus at the Teaching Hospital of Andalas University Muflihati Nurzain; Rina Gustia; Rini Gusya Liza; Ennesta Asri; Taufik Ashal; Abdiana
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 38 No. 1 (2026): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V38.1.2026.39-47

Abstract

Background: Lichen simplex chronicus (LSC) is a form of eczema that damages the skin barrier due to chronic itching. Stress is a contributing factor, leading to a persistent itch–scratch cycle that worsens lesion appearance and size. Purpose: This study aimed to describe the characteristics, severity, lesion location, and size, as well as stress levels, in patients with LSC. Methods: This descriptive cross-sectional study involved 42 LSC patients from the Dermatology and Venerology Outpatient Clinic at Andalas University Teaching Hospital, diagnosed between August 2019 and August 2023. Samples were selected using simple random sampling. Severity was measured using the EASI score, lesion location was based on medical records, lesion size was measured with a tape, and stress level was assessed using the PSS-10 questionnaire. Data were analyzed using univariate analysis (age, gender, occupation, severity, lesion location, and size). Result: The majority of LSC cases occurred in the 56–65 age group (42.9%), predominantly in women (57.1%), with civil servants being the most common occupation (28.6%). Most patients had mild to moderate severity (40.5%), with the ankle as the most frequent lesion site (26.2%), plaque as the most common lesion type (90.5%), and moderate stress being most prevalent (57.1%). Conclusion: Most patients were aged 56–65, predominantly female, and civil servants. Lesions were mainly mild to moderate in severity, commonly located on the ankle, with the plaque-type being most frequent. Moderate psychological stress was most prevalent.
Secondary Neoplasm Arising in Nevus Sebaceus of Jadassohn: A Case Report Emphasizing Early Recognition and Evaluation Agung Bima Putera; Ennesta Asri; Indah Indria Sari
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.332

Abstract

Background: Nevus sebaceus of Jadassohn (NSJ) is a congenital hamartomatous lesion involving epidermal, sebaceous, and adnexal structures. The lesion typically appears at birth or early childhood and remains stable for years. Secondary neoplastic transformations, either benign or malignant, may occur during adolescence or adulthood. Case: A 15-year-old girl presented with a yellowish plaque on the vertex of her scalp, first noticed at the age of five. Over time, the lesion enlarged, and a bluish-gray nodule developed two weeks prior to presentation, accompanied by localized pain. Dermatological examination revealed a cerebriform yellow-orange plaque with bluish nodules and alopecia. Dermoscopy showed yellow globules, a homogeneous yellow-orange background, and blue-gray ovoid nests. Histopathology confirmed features consistent with NSJ, including epidermal hyperplasia, papillomatosis, sebaceous glands opening into the epidermis, immature hair follicles, and ectopic apocrine glands. In addition, basaloid cell proliferation with peripheral palisading and melanin pigment suggested a secondary neoplasm. The overall findings are consistent with pigmented trichoblastoma, although the possibility of a pigmented basal cell carcinoma cannot be definitively ruled out. Discussion: The findings indicate neoplastic transformation arising within NSJ. Secondary tumors may develop even in adolescence, making early recognition crucial. Clinical changes such as rapid growth, color change, or pain should raise suspicion and prompt histopathological confirmation. Identifying secondary neoplasms influences management decisions, including the need for surgical excision.Conclusion: This case highlights the need for early recognition and thorough evaluation of NSJ lesions, particularly in adolescence, to detect and manage secondary neoplastic changes effectively.
One-Stage Earlobe-Based Transposition Flap After Full-Thickness Excision of a Congenital Verrucous Epidermal Naevus Spanning the Right Earlobe and Lateral Neck in a 3-Year-Old Boy: A Case Report With Dermoscopic and Histopathological Correlation Rizki Audita; Ennesta Asri; Indah Indria Sari
Scientific Journal of Dermatology and Venereology Vol. 4 No. 1 (2026): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v4i1.320

Abstract

Background: Verrucous epidermal naevus is a benign keratinocytic hamartoma that arises from post-zygotic somatic mutation and follows the lines of Blaschko. Lesions crossing the auricular and cervical units are uncommon and difficult to treat, because ablative and topical modalities clear the surface but leave the mutant keratinocyte clone. Objective: To describe the diagnosis, reconstructive decision and outcome of a one-stage earlobe-based transposition flap after full-thickness excision of such a lesion in a preschool child. Case Presentation: A 3-year-old boy was referred with a brown linear verrucous plaque measuring 7 × 0.75 × 0.1 cm, present on the right earlobe since birth and extending along the right lateral neck, thickening and becoming painful over three months. Dermoscopy showed cobblestone verrucous and papillomatous structures with brown to bluish-grey pigmentation and no melanocytic network. Absent pruritus and inflammation, and a normal systemic evaluation, excluded inflammatory linear verrucous epidermal naevus and epidermal naevus syndrome. Full-thickness excision under general anaesthesia with tumescent infiltration removed auricular and cervical specimens of 3.5 × 0.8 cm and 7 × 0.3 cm, and the defect was closed in one stage with an earlobe-based transposition flap. Histopathology showed hyperkeratosis, acanthosis and papillomatosis with focal hypergranulosis and vacuolated granular and spinous cells. Healing was uneventful; a hypertrophic scar confined to the cervical limb appeared by postoperative day 73. Conclusion: Complete excision with a one-stage earlobe-based transposition flap achieved definitive clearance and preserved auricular contour. Suprabasal vacuolation in a keratinocytic naevus should prompt keratin gene sequencing and reproductive counselling.