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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) Jurnal Sains dan Teknologi Indonesian Journal of Pharmaceutical Science and Technology Chimica et Natura Acta Jurnal Ilmiah Medicamento Jurnal Pengabdian UNDIKMA Hydrogen: Jurnal Kependidikan Kimia Jurnal Pengabdian Kepada Masyarakat Widya Mahadi Usadha
Dewa Ayu Ika Pramitha
Program Studi Diploma Tiga Farmasi Fakultas Farmasi Universitas Mahasaraswati Denpasar
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Journal : Jurnal Kimia (Journal of Chemistry)

 1 
BERBAGAI WAKTU PENYIMPANAN SECARA SPEKTROFOTOMETRI UV-VIS Dewa Ayu Ika Pramitha; Ni Made Suaniti; I Wayan Suarsa
Jurnal Kimia (Journal of Chemistry) Vol. 8, No. 1 Januari 2014
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.377 KB) | DOI: 10.24843/JCHEM.2014.v08.i01.p10

Abstract

This paper describes the determination of lamivudine content in pulveres by UV-Vis spectrophotometry. The purpose of this study was to determine the stability of lamivudine in various storage times. In this study, the validation of the method of the determination of lamivudine standard was also investigated with the following results: the linear regression equation y = 0.045x - 0.005 with correlation coefficient (r2) of 0.9998. Furthermore the detection limits obtained was of 0.46 µg/mL, quantitation limit of 1.53 µg/mL, the coefficient of variation of 0.23%, accuracy of 3.59%, and the recovery was of 96.41%. The stability of lamivudine in the samples decreased during the observation period i.e. 0, 7, 14, 21, and 28 days, during which the contents of lamivudine obtained were 87.46%, 86.22%, 84.44%; 76, 87%, 79.38%, respectively.
Co-Authors Agung Ari Chandra Wibawa Agustini, Ni Putu Dewi Arandika, I Wayan Wisma Chandra Wibawa, Agung Ari Debby Juliadi Dewi Maharani Indah Sari, Ni Komang Dewi, Kade Ayu Yasinta Dian Pratiwi Gunawan, I Putu Windra I Wayan Karta I Wayan Suarsa I WAYAN SUDIARSA I Wayan Surya Rahadi James Sibarani Kade Ayu Yasinta Dewi Ketut Agus Adrianta Kusuma Wardani, I Gusti Agung Ayu Megawati, Fitria Ni Komang Gita Sundari Ni Made Suaniti Ni Made Sukma Sanjiwani Ni Nyoman Ayu Kartika Yani Ni Putu Ayu Mirah Mariati Ni Putu Dewi Agustini Ni Wayan Yuliasih puguh santoso, puguh Putu Era Sandhi Kusuma Yuda Rahadi, I Wayan Surya Samidya, Ni Wayan Rias Sari, Luh De Cintya Kartika Sugiantari, Widiya Wardana, I Made Wisnu Wardani, I Gusti Agung Ayu Kusuma Yuliasih, Ni Wayan