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All Journal Sport and Fitness Journal E-Jurnal Medika Udayana Health Notions Aktiva : Jurnal Akuntansi dan Investasi ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Ners Bali Anatomy Journal Journal of Social Research Indonesian Andrology and Biomedical Journal
I Gusti Ayu Widianti
Department Of Anatomy, Medical Faculty, Universitas Udayana
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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The Relationship Between Varicocele in Infertile Male and Intrauterine Insemination Success at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Andhika Bhayangkara Putra Anak Agung Gde; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 3 No. 2 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v3i2.35877

Abstract

Background: Assisted Reproductive Technology (ART), such as intrauterine insemination (IUI), can be an option for infertile couples who are expecting a pregnancy. However, the success of IUI can be influenced by various factors, one of which is varicocele.   Objective: This study aims to determine the association between varicocele and IUI success. Methods: This study is an analytical cross-sectional study using patient medical records. The sample of this study was male patients aged 25-45 years with infertility and undergoing IUI in the period April to June 2021 at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar. The sampling technique used, purposive sampling, was selected based on inclusion and exclusion criteria. Based on the criteria, this study selected 32 samples. Result: From 32 participants, 5 had varicocele (15.6%), and 27  were without varicocele (84.4%). In this study, we found 12 success pregnancy after IUI (37.5%), with 3 participants having varicocele (9.4%) and 9 participants without varicocele (28.1%). The chi-square analysis carried out obtained the results (p>0.05), and the calculation of the relative risk got the result (RR=0.600). Conclusion: This study showed no significant association between varicocele in infertile men and the success of IUI. The RR calculation showed that varicocele was not a risk factor for IUI failure.
Sperm Agglutination in Infertile Men and The Success Rate of Intrauterine Insemination in Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Anak Agung Sintya Padma Dewi; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 4 No. 1 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v4i1.42110

Abstract

Background: Every human being, especially a married couple, wants children. Obstacles to obtaining children are called infertility. One of the Assisted Reproductive Technology (ART) procedures used for treating infertility is intrauterine insemination (IUI), a non-invasive procedure with affordable costs. The success of IUI is influenced by many factors, one of which is sperm agglutination. Objective: This study determined the relationship between sperm agglutination and the success rate of the IUI procedure. Methods: The study is a descriptive-analytic study with a cross-sectional approach. The sample collection technique uses non-probability. The data used were medical records of male patients diagnosed with infertility, aged 25-45 years, and undergoing IUI procedures at the Rumah Sakit Ibu dan Anak Puri Bunda Denpasar from January to July 2022. Results: Of the 91 samples obtained, 9 people experienced sperm agglutination (9,9%), and 82 people did not experience sperm agglutination (90,1%). The success rate of the IUI procedure was 29 people (31,9%), 1 person (11.1%) experiencing sperm agglutination, and 28 people (34,1%) not experiencing sperm agglutination. Fisher's Exact test carried out has obtained a result (p=0.263). And the value of the odds ratio (OR) obtained=0.241) Conclusion: This study concluded that there is no significant relationship between sperm agglutination in infertile men and the success rate of the IUI procedure. The value of OR showed sperm agglutination is not included in the factors that affect the success rate of IUI. Keywords: Sperm Agglutination, Intrauterine Insemination, Male Infertility
Leukospermia in Infertile Men and Successful Intrauterine Insemination at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Anak Agung Ngurah Perdana Anantadiva; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 4 No. 1 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v4i1.41761

Abstract

Infertility is a condition after a year of regular sexual intercourse, without the use of contraceptives, and ends with the absence of pregnancy. Intrauterine Insemination (IUI) is a procedure that is widely used in fertility clinics and is usually the first treatment option in patients who are experiencing infertility disorders, diagnosis of infertility due to cervical factors, diagnosis of factor infertility in men, and diagnosis of unexplained infertility. the cause. IUI is also a simple, inexpensive, and quite effective infertility treatment. One of the factors that can influence the success of IUI is leukospermia. This study is an analytical study using a cross-sectional design and using medical records of patients diagnosed with infertility, aged from 25 to 45 years, and undergoing IUI procedures from January to June 2022 at the RSIA Puri Bunda Denpasar. The sampling method in this study used a purposive sampling method which was selected based on inclusion and exclusion criteria. In this study, 53 samples were obtained. Of the 53 samples that have been collected, 13 people experienced leukospermia (24.5%), 40 people were non-leukospermic (75.5%). The success of IUI in this study was 17 people (32.1%) consisting of 3 leukospermic (23.1%) and 14 non-leukospermic (35.0%). The results of the Fisher's Exact test obtained, namely the p value = 0.511, it can be concluded that leukospermia with the success of IUI does not have a significant relationship. Calculation of odds ratio (OR) obtained a figure of 1.759 (CI95% 0,423-7,610).
Post-Preparation Total Motile Sperm Count in Infertile Men and The Success Rate of Intrauterine Insemination at Rumah Sakit Kasih Ibu Denpasar in 2022 Wibawa, I Kadek Sadam; I Gusti Ngurah Pramesemara; I Made Oka Negara; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 5 No. 1 (2024): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v5i1.53777

Abstract

Background: Every married couple hopes to have children, but not all can fulfil that desire. A married couple finds themselves unable to achieve pregnancy after 12 months of regular unprotected sexual intercourse, which can be called infertility. Infertility can also occur in men. In dealing with infertility, intrauterine insemination (IUI) is a cost-effective and non-invasive Assisted Reproductive Technology (ART) procedure. The condition of male infertility can be detected through semen analysis. One of the parameters in semen analysis is the total motile sperm count (TMSC). Objective: This research seeks to establish the relationship between post-preparation TMSC and the success rate of the IUI procedure. Methods: This research adopts a descriptive-analytical design employing a cross-sectional methodology. Non-probability sampling was utilized as the sampling technique, and the data analyzed were secondary data from the medical records of male patients aged 25 to 45 years old diagnosed with infertility. The subjects had undergone IUI at Rumah Sakit Kasih Ibu Denpasar from January 1 to December 31, 2022. Results: From the 35 obtained samples, 12 individuals (34.3%) had a post-preparation TMSC of ≥10 í— 106, while 23 individuals (65.7%) had a post-preparation TMSC of <10 í— 106. The success rate of the Intrauterine Insemination (IUI) procedure was 17.1%, with 4 couples (33.3%) having a post-preparation TMSC of ≥10 í— 106 and 2 couples (8.7%) with a post-preparation TMSC of <10 í— 106. The Fisher's Exact test carried out has obtained a result (p=0.151), while the value of the odds ratio (OR) obtained (OR=5.250) Conclusion: Based on statistical analysis, it can be concluded that there is no significant association between post-preparation TMSC in infertile men and the success rate of IUI procedures (p > 0.05). The odds ratio (OR) obtained is 5.250 (95% CI 0.799-34.496).
Pengaruh Ekstrak Etanol Kubis Ungu terhadap Kadar Malondialdehida, Superoksida Dismutase dan Derajat Steatosis Hati pada Tikus Model NAFLD Ni Made Gita Kusuma Dewi; I Wayan Sugiritama; I Gusti Ayu Widianti; I Nyoman Gede Wardana; Desak Ketut Ernawati; I Putu Bayu Mayura
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.43013

Abstract

Non-Alcoholic Fatty Liver Disease (NAFLD) adalah gangguan hati kronis yang ditandai dengan akumulasi lemak berlebih dalam hepatosit dan berkaitan dengan sindrom metabolik. Stres oksidatif berperan dalam progresi NAFLD, dengan kadar malondialdehida (MDA) dan aktivitas superoksida dismutase (SOD) sebagai biomarker. Kubis ungu (Brassica oleracea var. capitata L.) memiliki kandungan antosianin tinggi yang bersifat antioksidan, namun efek hepatoprotektifnya terhadap NAFLD masih perlu diteliti lebih lanjut. Penelitian ini bertujuan untuk mengevaluasi efek hepatoprotektif ekstrak etanol kubis ungu terhadap kadar MDA dan SOD serta derajat steatosis hati pada tikus Wistar jantan yang diinduksi dengan diet tinggi lemak dan karbon tetraklorida (CCl₄). Studi ini menggunakan desain post-test only control group dengan empat kelompok: kontrol negatif dan tiga kelompok perlakuan yang menerima ekstrak etanol kubis ungu dengan dosis 100 mg/kg BB, 200 mg/kg BB, dan 400 mg/kg BB. Analisis menggunakan ANOVA dan uji post-hoc Tukey HSD menunjukkan bahwa ekstrak kubis ungu secara signifikan mencegah peningkatan kadar MDA (p < 0,05), mencegah penurunan aktivitas SOD (p < 0,05), serta mencegah peningkatan derajat steatosis, dengan dosis paling efektif 200 mg/kg BB. Hasil ini menunjukkan bahwa ekstrak etanol kubis ungu memiliki efek hepatoprotektif dan berpotensi sebagai agen terapeutik alami untuk pencegahan NAFLD.
The Relationship Between Knowledge And Preventive Behavior of Adhesive Capsulitis In Fried Rice Vendors In Denpasar City, Bali Province I Gusti Ayu Widianti; Anak Agung Ayu Tri Pradnya Purantara; Yuliana Yuliana; Gede Wirata
Journal of Social Research Vol. 5 No. 2 (2026): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v5i2.3007

Abstract

The culinary business, including fried rice vendors, had the potential to experience musculoskeletal complaints such as adhesive capsulitis (frozen shoulder), which was triggered by the lack of movement in the passive shoulder or movements inversely proportional to the activity of the opposite shoulder during work. Adhesive capsulitis was characterized by pain, stiffness, and loss of shoulder range of motion. Early management was important to prevent the disease from progressing to the frozen phase. A high level of knowledge could help an individual apply disease prevention behavior. This study aimed to analyze the relationship between knowledge and preventive behavior regarding adhesive capsulitis in the shoulders of cart-based fried rice vendors in Denpasar City, Bali Province. The research used an observational analytic design with a cross-sectional approach. The sample consisted of 40 cart-based fried rice vendors, selected using the purposive sampling technique. Data were collected through questionnaires and interviews. Data analysis was performed using the Spearman correlation test because the data scale was ordinal. The majority of respondents had a low level of knowledge (50.0%) and low preventive behavior (55.0%). The Spearman correlation test showed a significant (p=0.000), very strong (r=0.828), and unidirectional relationship between knowledge and preventive behavior regarding adhesive capsulitis. The conclusion of the study was that there was a significant, strong, and unidirectional relationship between knowledge and preventive behavior regarding adhesive capsulitis of fried rice vendors in Denpasar City, Bali Province.
The Association Between Insomnia and Erectile Dysfunction Among Udayana University Hospital Employees in 2025 Putu Anindita Wira Cahyani; I Made Oka Negara; I Gusti Ngurah Pramesemara; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 7 No. 1 (2026): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v7i1.84686

Abstract

Background : Erectile dysfunction is the inability to achieve or maintain an erection sufficient for sexual activity. Insomnia is a sleep disorder that commonly occurs in individuals of productive age and may impact physiological functions of the body, including erectile function. Objective : This study aimed to determine the association between insomnia and erectile dysfunction among male employees of Udayana University Hospital. Methods : This analytical study was conducted with a cross-sectional design. The research respondents were obtained through purposive sampling and comprised 42 male employees aged 28–40 years. Data were collected using the Insomnia Severity Index (ISI) questionnaire to assess insomnia, and the International Index of Erectile Function-5 (IIEF-5) to assess erectile function. The collected data were then processed and analysed using SPSS 27 software. Results : Results indicated that 35.8% of respondents experienced insomnia, whereas 45.3% of respondents experienced erectile dysfunction. The chi-square test showed that males with insomnia had a four-fold higher risk of experiencing erectile dysfunction compared to those without insomnia (p=0.038). Conclusion : There is a significant association between insomnia and erectile dysfunction among male employees of Udayana University Hospital. Keywords : Insomnia, erectile dysfunction, IIEF-5 questionnaire, ISI questionnaire
Co-Authors Adhitya Bayu S Aditya Permana Adriyanto Amelia Heryanto Anak Agung Ayu Tri Pradnya Purantara Anak Agung Ngurah Perdana Anantadiva Anak Agung Sintya Padma Dewi Andhika Bhayangkara Putra Anak Agung Gde Archana Laxmi Pathmanathan Asrul Sani Bagus Komang Satriyasa Desak Ketut Ernawati Dewa Putu Gede Purwa Samatra Elisabeth Matrona Sintia Pareira Gede Wirata Gusti A Putu Mentari Saga P I Dewa Putu Sutjana I Gusti Ngurah Pramesemara I Gusti Ngurah Pramesemara I Made Krisna Dinata I Nyoman Adi Putra I Nyoman Gede Wardana I Nyoman Mangku Karmaya I P G. Adiatmika I Putu Bayu Mayura I Wayan Sugiritama Made Oka Negara Merlynda Ayu Rara Dini Mohd Fauzan Arif Bin Mat Nudin Muhamad Baidhowi Primadi Ni Made Gita Kusuma Dewi Nur Fitriyah Putu Anindita Wira Cahyani Putu Susilawati Sawitri, Anak Agung Sagung Sugijanto - Susy Purnawati Wahyuddin, Wahyuddin Wibawa, I Kadek Sadam Yukhi Kurniawan Yuliana Yuliana