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All Journal Buletin Udayana Mengabdi ISM (Intisari Sains Medis) : Jurnal Kedokteran Indonesian Andrology and Biomedical Journal

I Gusti Ngurah Pramesemara

Departemen Andrologi Dan Seksologi, Fakultas Kedokteran, Universitas Udayana, Bali, Indonesia

Author-ID : 4005809

Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology

Published : 16 Documents Claim Missing Document

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Relationship Between Smoker Male Partner and Intrauterine Insemination Success in Kasih Ibu General Hospital Denpasar Albert Salim; Yukhi Kurniawan; I Gusti Ngurah Pramesemara
Indonesian Andrology and Biomedical Journal Vol. 2 No. 2 (2021): December
Publisher : Universitas Airlangga

Background: Assisted reproductive technology, one of which is intrauterine insemination (IUI) allows infertile couples to get pregnant. The pregnancy success of IUI procedure varies among individuals. Objective: The study aim is to determine whether there is a relationship between smoker male partners and IUI success. Methods: This research is an analytic study with cross-sectional approach conducted at Kasih Ibu General Hospital Denpasar with purposive sampling technique. There are 35 male couples aged 25-50 years who underwent the IUI procedure selected as samples. The research data was gathered from patient's medical records and statistically analyzed using the Chi-Square test. Results: The study found that of the 35 samples, 13 (37.1%) were smokers, whereas 22 (62.9%) male partners were non-smokers. There were 6 (17.1%) samples’ partners who were pregnant after undergoing the IUI procedure, and 29 (82.9%) samples’ partners were not pregnant. It was found that there was no significant relationship between male partner smokers and the success of IUI at Kasih Ibu General Hospital Denpasar (p=0.832). However, in descriptive analysis and relative risk calculation, smoker male partner is less likely to achieve pregnancy than non-smoker’s male partner (RR=0.85). Conclusion: Smoker male partners may not contribute to IUI success. Further studies should be done with a higher number of samples, multicenter, and more controlled risk factors to make it more accurate in determining the relationship.

Relationship Between Waist Circumference and The Event of Andropause in Male Employees in Government Institutions of Badung Regency Anak Agung Ayu Dian Indah Lestari; I Gusti Ngurah Pramesemara; Yukhi Kurniawan
Indonesian Andrology and Biomedical Journal Vol. 2 No. 1 (2021): June
Publisher : Universitas Airlangga

Background: Andropause occurs with slow development and is a physiological process in males. Andropause symptoms arise vary in individuals. One of the factors that influence these symptoms is obesity, especially central obesity with a waist circumference of >90 cm. Objective: The purpose of this study is to show the relationship between waist circumference and the event of andropause. Methods: This research is an analytical study with a cross-sectional study approach conducted in one of the government institutions of Badung Regency, Bali Province. The sampling technique used was purposive sampling. The subjects consisted of 40 male employees at aged around 35-60 years. The research data were obtained from filling out the Androgen Deficiency in Aging Male (ADAM) score questionnaire and direct measurement of waist circumference. The statistical analysis used was the Chi-Square test. Results: The results showed that from 40 subjects, 23 (57.5%) subjects had a waist circumference of >90 cm, and a normal waist circumference of <90 cm in 17 (42.5%) subjects. There were 22 subjects (55.0%) who experienced andropause and 18 (45.0%) subjects who did not experience andropause. It was found that there was a significant relationship between waist circumference and the event of andropause among male employees in government institutions of Badung Regency (p = 0.001, OR = 11.7). Conclusion: The study has found that higher in waist circumference may contribute in the event of andropause. For further studies should takes a higher number of subjects to make it more accurate in wider population.

Relationship Between the Age of Female Partner and the Intrauterine Insemination Success in Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Alycia Madeleine; Yukhi Kurniawan; I Gusti Ngurah Pramesemara
Indonesian Andrology and Biomedical Journal Vol. 3 No. 1 (2022): June
Publisher : Universitas Airlangga

Infertility is the inability of couples who have regular sexual intercourse without using protection to achieve pregnancy within one year. The prevalence of infertility was 21.3% in Indonesia. Intrauterine Insemination (IUI) is an assisted reproductive technology chosen by infertile couples to have children. Various factors influence the success of IUI. One factor that influences the success of IUI is the female partner’s age. To determine the relationship between the age of female partners and the success of IUI. This study is descriptive-analytical research with the Cross-Sectional method using secondary data obtained from medical records of patients who underwent IUI procedures from January to March 2020 at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar. Total research subjects are 31 patients with an average age of 32 years. Positive pregnancies in female partners aged 25-35 years are 8 patients (33,3%) and female partners aged 35-40 are 1 patient (14.3%). Most patients had secondary infertility with a duration of 1-3 years. There is no relation between the increasing age of female partners and the decreasing success of IUI at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar (p=0,329). But female partners aged 25-35 years tended to have a positive pregnancy 2,333 times higher than female partners aged 35-40 years (RR=2,333; CI 95%: 0,349-15,612).

Relationship Between Body Mass Index and Male Infertility at Kasih Ibu General Hospital Denpasar Amelia Heryanto; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 3 No. 1 (2022): June
Publisher : Universitas Airlangga

Infertility can occur in men, characterized by the inability to make pregnancy in the partner. The causes of male infertility are multifactorial, one of which is obesity. Obesity parameter by body mass index >25 kg/m2. This study purposes of determining the relationship between obesity with body mass index measurement and male infertility. This type of research is an analytical cross-sectional study. This research was located at the Kasih Ibu General Hospital Denpasar. Purposive sampling was chosen as the sampling technique. The samples were 50 male patients aged 25-45 years who checked themselves at the Kasih Ibu General Hospital Denpasar between January and December 2020. All research data could be seen from the patient's medical records. The Pearson Chi-Square test was used to analyze the data. The results were 26 subjects (52%) with BMI >25 kg/m2 (obese) and 24 subjects (48%) with BMI <25 kg/m2 (non-obese). About 28 subjects (56%) were infertile, and 22 subjects (44%) were fertile. This study found that body mass index was significantly associated with infertility in male patients at Kasih Ibu General Hospital Denpasar. Obese men had a 2,308 higher risk of infertility than men were not obese (p = 0.002, RR = 2.308 (CI95% 1.262-4.220). The study has found that obesity may contribute to the event of male infertility. For further research should use a larger sample size to make it more accurate in population.

Relationship of Type 2 Diabetes Mellitus Duration with The Occurrence of Erectile Dysfunction at Puskesmas Denpasar Barat I Alexander Petra Sihite; I Gusti Ngurah Pramesemara; I Wayan Surudarma
Indonesian Andrology and Biomedical Journal Vol. 2 No. 1 (2021): June
Publisher : Universitas Airlangga

Background: Type 2 diabetes mellitus is a metabolic disease that characterized by high blood sugar levels. This condition is often not noticed immediately and usually patient starting to realize it when complications have been occurred. A long-term complication of type 2 DM that occurred in men is erectile dysfunction (ED). ED is a condition when a person is unable to achieve or maintain an erection for sexual intercourse. One factor that influence the occurrence of ED and its severity in type 2 DM patients is the duration of the disease. Objective: The aim of this study was to determine the relationship of type 2 DM duration and the occurrence of ED. Methods: This study is an observational analytic cross-sectional study conducted at the Puskesmas (Public Health Center) Denpasar Barat I. The research data was obtained through medical record data and fill the International Index of Erectile Function (IIEF-5) questionnaire on 36 type 2 DM patients aged around 40-60 years. The statistical analysis used was Fisher's exact test. Results: The results showed that of the 36 samples, 19 (52.8%) samples had type 2 DM <24 months and 17 (47.2%) samples had type 2 DM >24 months. It was found that 5 (13.9%) samples did not experience ED while the rest experienced ED with different severity. There was a significant relationship between the type 2 DM duration and the occurrence of erectile dysfunction at Puskesmas Denpasar Barat I (p = 0.022). Conclusion: Study has found that type 2 DM patients with the longer duration (>24 months) have a higher occurrence of ED and tended to be more severe compared to those with shorter duration (<24 months). Further studies should be performed with higher number of patients and more controlled risk factor so it will be more accurate in determining the relationship between the duration of type 2 DM and ED.

PENDIDIKAN SEKSUAL BAGI ORANG TUA DAN GURU REMAJA DENGAN BERKEBUTUHAN KHUSUS DI SLB/A NEGERI DENPASAR I Gusti Ayu Pramitaresthi; I. G. N. Pramesemara; I. A. Sanjiwani; N. M. D. Kurniasari
Buletin Udayana Mengabdi Vol 20 No 1 (2021): Buletin Udayana Mengabdi
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Pendidikan seksual sangatlah penting diajarkan untuk remaja, terlebih remaja dengan kebutuhan khusus. Remaja dengan kebutuhan khusus pada umumnya kekurangan informasi yang berhubungan dengan perkembangan seksualitas. Hal tersebut disebabkan tidak didapatkannya informasi mengenai pendidikan seksual dari orang tua dan gurunya. Pada dasarnya remaja berkebutuhan khusus tidak mempunyai keberanian yang cukup untuk bercerita dan tidak mendapatkan informasi yang bisa diperoleh dari artikel maupun buku. Orang tua merupakan pihak yang paling dekat dan banyak waktunya bersama anak.Sedangkan guru merupakan pihak yang bertanggungjawab mengajarkan kemandirian mereka di sekolah. Oleh karena itu maka diperlukannya pendidikan seksual bagi orangtua dan guru agar nantinya bisa diberikan ke remaja berkebutuhan khusus. Tujuan dari kegiatan ini yaitu memberikan pemahaman terkait pentingnya kesehatan reproduksi dan seksualitas pada guru dan orang tua dengan remaja berkebutuhan khusus. Metode kegiatan ini berupa ceramah, diskusi tanya jawab dan pemberian kuesioner pre-test dan post-test yang dilaksanakan pada tanggal 5 Oktober 2020 melalui webinar dengan menggunakan aplikasi Cisco Webex yang dihadiri oleh orangtua dan guru kemudian dilanjutkan dengan konsultasi melalui group Whatsapp. Hasil analisis kuesioner didapatkan adanya peningkatan pengetahuan peserta setelah diberikan pendidikan kesehatan. Simpulan dan implikasinya diharapkan setelah ini, orangtua dan guru dapat memberikan pendidikan kesehatan reproduksi dan seksualitas kepada remaja berkebutuhan khusus. Kata kunci : Pendidikan Seksual, Orang tua, Guru, Remaja Berkebutuhan Khusus

PENDIDIKAN KESEHATAN ‘BISIK SEKS’ BAGI ORANG DENGAN HIV DAN KONSELOR HIV DALAM MENGHADAPI TATANAN KEHIDUPAN ERA BARU DAMPAK COVID-19 DI KOTA DENPASAR N. A. J. Raya; I. G. N. Pramesemara; M. H. S. Nugraha; G. Wirata
Buletin Udayana Mengabdi Vol 20 No 4 (2021): Buletin Udayana Mengabdi
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Setiap orang perlu untuk menjaga sistem imunitasnya pada masa COVID-19, di sisi lainnya orang dengan HIV memiliki sistem imun yang lemah apabila tidak disiplin mengonsumsi antiretroviral. Informasi spesifik tentang merawat dan menjaga diri pada tatanan kehidupan era baru dampak COVID-19 bagi orang dengan HIV masih diperlukan. Tujuan dari pengabdian masyarakat ini yaitu memberikan edukasi tentang cara menjaga kebugaran fisik dan kesehatan seksual bagi orang dengan HIV dan konselor HIV di tengah keterbatasan akses informasi selama masa pandemi COVID-19. Metode pelaksanaan kegiatan ini dalam bentuk ceramah pemberian materi dan diskusi tanya jawab, serta diberikan pre-test dan post-test yang dilaksanakan pada 14 Agustus 2021 secara daring menggunakan aplikasi Zoom. Hasil analisis pre-test dan post-test dari 40 peserta dengan uji Wilcoxon didapatkan adanya pengaruh pemberian pengetahuan setelah diberikan pendidikan kesehatan (p = 0,000; Z = -4,508). Skor tingkat pengetahuan baik meningkat dari 7,5% menjadi 42,5% dan tingkat pengetahuan kurang menurun dari 32,5% menjadi 0%. Simpulan dan implikasi dari kegiatan pengabdian masyarakat ini yaitu terdapat peningkatan pengetahuan yang dapat diimplimentasikan dalam kehidupan sehari-hari, sehingga imun, kondisi tubuh, dan kesehatan seksual orang dengan HIV tetap bugar dan sehat. Informasi yang didapat dalam kegiatan ini dapat diteruskan oleh konselor HIV dalam mendampingi klien dengan HIV.

Administration of sildenafil citrate not able to reduced hs-CRP on erectile dysfunction patient at Doctor Soetomo Hospital, Surabaya, Indonesia I Gusti Ngurah Pramesemara; Rossy Sintya Marthasari; Rezia Octarina; Ahmad Ricardo Syukur Silalahi; Judie Hartono; Tjahjo Djojo Tanojo
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Background: Phosphodiesterase type-5 (PDE5) inhibitors was the first choice for the oral treatment of erectile dysfunction because of its ability to prevent endothelial dysfunction and restored erectile function properly. However, the inflammatory parameter such as hs-CRP can be used to assess the performance of PDE5 inhibitors as well as clinical questionnaires, IIEF-5, and EHS. So that, this study aims to determine the effect of PDE5 inhibitors administration such as sildenafil citrate 50 mg per day can decrease the value of hs-CRP, as well as increased the IIEF-5 and EHS at Dr. Soetomo General Hospital.Methods: A true clinical experimental studies used pretest and posttest control group design were carried out among 20 patients during 4 weeks. In the next 2 weeks, the crossover was conducted among respondents for the washout period whereas divided into 2 groups, control (K1 and K2) and treatment (P1 and P2). Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 16.0 software for Windows.Results: The average age of group K1 and P2 was 51 Â± 12.07 years old whereas 48.60 Â± 15.40 years old in group P1 and K2. The research was conducted in Andrology Clinic of Doctor Soetomo Hospital in Surabaya during June to November 2017. The research data were not normally distributed, then analyzed by two-tail T-group tests and Wilcoxon test at significance level Î±=0.05. The results showed that PDE5 inhibitors did not decrease the hs-CRP significantly (p>0.05), but increased EHS (p<0.05) and increased IIEF-5 (p<0.05) significantly.Conclusion: This study concluded that the administration of sildenafil citrate per day by oral increased the EHS and IIEF-5, but not able to reduced hs-CRP in patients with erectile dysfunction significantly.

Mobile Voluntary Counseling Testing (VCT) pada Perkumpulan Keluarga Berencana Indonesia (PKBI) Daerah Bali: studi empiris dalam upaya penanganan HIV-AIDS I Gusti Ngurah Pramesemara; Ninik Andrias; Dyah Pradnyaparamita Duarsa
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Nowadays, the transmission of HIV-AIDS is mostly due to risky sexual activity and found in the heterosexual group, around 76.5%. The high rate may be due to stigma and discrimination in society, so risk people are reluctant to come for a check-up or treatment. This study aims to evaluate the comprehensive approach from the upstream to downstream and culture based in dealing with HIV-AIDS in the form of Mobile Voluntary Counseling Testing (VCT) that has been carried out by the Indonesian Planned Parenthood Association (IPPA) Bali, Indonesia.Methods: This descriptive cross sectional study was conducted in the 2016-2018 period in all regions of Bali, Indonesia, by convenience sampling technique. There are differences in the total number of services that have been performed which include Post-Test (+) counselling, Post-Test Counseling (-), rapid test evaluation, HIV counselling and prevention measures, as well as VCT Pre-Test counselling. The medical team and counsellor came together to meet directly with groups at risk of HIV-AIDS infection called key populations, such as commercial sex workers, transvestites, drug users, and homosexuals. The data obtained were analyzed descriptively using Microsoft Excel for Windows.Results: The results of this descriptive empirical study show that the overall Post-Test (+) counselling was conducted 9 times in 2016 (2 times), 2017 (3 times), and 2018 (4 times). Whereas in Post-Test (-) counselling there were 161 examinations in 2016, 105 times (2017), and 125 (2018). In the last 3 years, 1,472 investigations have been carried out, of which 652 times were in 2016, 367 times in 2017, and 453 times in 2018.Conclusion: Mobile VCT of IPPA Bali may be one of the effective efforts in responding to the challenges of people who tend to be taboo and less concerned about sexual and reproductive health issues. Latar Belakang: Saat ini penularan HIV-AIDS sebagian besar disebabkan oleh aktivitas seksual yang berisiko dan ditemukan pada kelompok heteroseksual sekitar 76,5%. Tingginya angka tersebut mungkin disebabkan oleh stigma dan diskriminasi di masyarakat, sehingga orang yang berisiko enggan datang untuk melakukan pemeriksaan atau perawatan. Penelitian ini bertujuan untuk mengevaluasi pendekatan komprehensif dari hulu ke hilir dan budaya berbasis dalam berurusan dengan HIV-AIDS dalam bentuk Pengujian Konseling Sukarela Seluler (VCT) yang telah dilakukan oleh PKBI Bali, Indonesia.Metode: Penelitian deskriptif dengan pendekatan potong lintang ini dilakukan dalam rentang periode 2016-2018 di seluruh daerah Bali, Indonesia dengan menggunakan teknik convenience sampling. Terdapat perbedaan jumlah total layanan yang telah dilakukan dimana meliputi konseling Post-Test (+), Konseling Post-Test (-), evaluasi rapid test, konseling HIV dan tindakan pencegahan, maupun konseling VCT Pre-Test. Tim medis dan konselor datang bersama untuk bertemu langsung dengan kelompok yang berisiko terinfeksi HIV-AIDS yang disebut populasi kunci, seperti pekerja seks komersial, waria, pengguna narkoba, dan homoseksual. Data yang diperoleh dianalisis secara deskriptif menggunakan Microsoft Excel untuk Windows.Hasil: Hasil studi empiris deskriptif ini menunjukkan bahwa telah dilakukan 9 kali konseling Post-Test (+) baik pada tahun 2016 (2 kali), 2017 (3 kali), dan 2018 (4 kali). Sedangkan pada konseling Post-Test (-) terdapat 161 kali pemeriksaan pada tahun 2016, 105 kali (2017), dan 125 (2018). Secara keseluruhan dalam 3 tahun terakhir telah dilakukan sebanyak 1.472 pemeriksaan dimana sebanyak 652 kali pada tahun 2016, 367 kali pada tahun 2017, dan 453 kali pada tahun 2018.Kesimpulan: Mobile VCT PKBI Bali dapat menjadi salah satu upaya efektif dalam menanggapi tantangan orang-orang yang cenderung tabu dan kurang peduli tentang masalah kesehatan seksual dan reproduksi.

Hubungan andropause dengan skor IPSS pada pegawai di institusi pusat pemerintahan Kabupaten Badung-Bali Assuncao Caviota Da Silva Pinto; Yukhi Kurniawan; I Gusti Ngurah Pramesemara
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Background: Andropause is a term which indicate reduced male testosterone levels. The mechanism of andropause is due to decreased male reproductive function which results in decreased levels of testosterone in the blood below normal levels. On the other hand, almost 50% of men aged 45-60 years experience complaints of urination due to Benign Prostate Hyperplasia (BPH). Until now, BPH is believed to be related to the aging process and decreased levels of the hormone testosterone or andropause. However, no clear evidence indicate a relathionship between andropause and severe micturition probelm. This study aims to determine the relathionship of andropause and the IPSS score.Methods: This study is an analytic observational study with a cross sectional method. Sampling in this study using purposive sampling with respondent taken from the Central Government Institution of Badung Regency, Bali. The total number of research respondents was 40 man. Symptoms and signs of andropause were evaluated using the Androgen Deficiency in the Aging Male (ADAM) questionnaire, while the degree of symptoms of micturition was determined by the International Prostate Symptom Score (IPSS). The data was analyze descriptively and analytically with Chi-square to determine the relationship between andropause status and the degree of micturition problem.Results: Complaints of moderate micturition problem were the most common complaint in andropause respondents (45.5%) while mild complaints were the most common among respondents who did not experience andropause (72.2%). The results showed a significant relationship between respondents who experienced andropause and the tendency to complain of symptoms of obstruction due to prostate enlargement as assessed by the IPSS score (p = 0.038).Conclusion: There is a significant relationship between respondents experiencing andropause and the tendency to complain of symptoms of obstruction due to prostate enlargement. Pendahuluan: Andropause merupakan suatu istilah yang berarti menurunnya kadar hormon testosteron pada laki-laki. Mekanisme terjadinya andropause adalah karena menurunnya fungsi reproduksi laki-laki yang berakibat menurunnya kadar testosteron dalam darah dibawah angka normal. Disisi lain, laki-laki usia 45-60 tahun hampir 50% mengalami keluhan miksi akibat Benign Prostate Hyperplasia (BPH). BPH hingga saat ini diyakini berhubungan dengan proses penuaan dan penuruan kadar hormon testosteron atau andropause. Akan tetapi belum banyak bukti menunjukan hubungan andropause dengan beratnya gangguan miksi akibat BPH. Penelitian ini bertujuan untuk mengetahui hubungan status andropause dengan skor IPSS.Metode: Penelitian ini merupakan penelitian observasional analitik dengan metode potong lintang. Pengambilan sampel pada penelitian ini menggunakan purposive sampling dengan responden diambil dari Institusi Pusat Pemerintah Kabupaten Badung, Bali. Keseluruhan responden penelitian berjumlah 40 orang. Gejala dan tanda andropause dievaluasi dengan kuisioner Androgen Deficiency in the Aging Male (ADAM) sedangkan derajat gejala gangguan miksi ditetukan dengan skor International Prostate Symptom Score (IPSS). Analisis data berupa deskriptif serta analitik dengan Chi-square untuk menentukan hubungan status andropause dengan derajat gangguan miksi.Hasil: Keluhan gangguan miksi derajat sedang merupakan tingkat keluhan paling umum pada responden andropause (45,5%) sedangkan keluhan ringan merupakan keluhan paling umum pada responden tidak mengalami andropause (72,2%). Hasil penelitian menunjukkan hubungan yang signifikan antara responden yang mengalami andropause dan kecenderungan mengeluhkan gejala obstruksi akibat pembesaran prostat yang dinilai melalui Skor IPSS (p=0,038).Simpulan: Terdapat hubungan yang signifikan antara responden yang mengalami andropause dan kecenderungan mengeluhkan gejala obstruksi akibat pembesaran prostat.

Co-Authors Ahmad Ricardo Syukur Silalahi Albert Salim Alexander Petra Sihite Alexander Petra Sihite Alycia Madeleine Amelia Heryanto Anak Agung Ayu Dian Indah Lestari Anak Agung Gde Ryantha Indra Pranamartha Anak Agung Ngurah Perdana Anantadiva Anak Agung Sintya Padma Dewi Andhika Bhayangkara Putra Anak Agung Gde Assuncao Caviota Da Silva Pinto Benediktus Bosman Ariesta Gusti Putu Dwijo Anargha Sindhughosa Dyah Pradnyaparmita Duarsa G. Wirata I Gusti Ayu Pramitaresthi I Gusti Ayu Widianti I Putu Yuda Prabawa I Wayan Surudarma I Wayan Surudarma I. A. Sanjiwani I.A. Sanjiwani Ida Bagus Amertha Putra Manuaba Judie Hartono L.M. Puspita M. H. S. Nugraha N. A. J. Raya Ni Made Dian Hartaningsih Ni Made Dian Kurniasari Ninik Andrias Rezia Octarina Rossy Sintya Marthasari Tanojo, Tjahjo Djojo Yukhi Kurniawan Yukhi Kurniawan Yukhi Kurniawan Kurniawan

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