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The percentage of macrophage numbers in rat model of sciatic nerve crush injury Satrio Wicaksono; Muhammad Ghufron; Rina Susilowati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 47, No 01 (2015)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2044.327 KB) | DOI: 10.19106/JMedSci004701201501

Abstract

ABSTRACTExcessive accumulation of macrophages in sciatic nerve fascicles inhibits regeneration of peripheral nerves. The aim of this study is to determine the percentage of the macrophages inside and outside of the fascicles at the proximal, at the site of injury and at the distal segment of rat model of sciatic nerve crush injury. Thirty male 3 months age Wistar rats of 200-230 g were divided into sham-operation group and crush injury group. Termination was performed on day 3, 7, and 14 after crush injury. Immunohistochemical examination was done using anti CD68 antibody. Counting of immunopositive and immunonegative cells was done on three representative fields for extrafascicular and intrafascicular area of proximal, injury and distal segments. The data was presented as percentage of immunopositive cells. The percentage of the macrophages was significantly increased in crush injury group compared to the sham-operated group in all segments of the peripheral nerves. While the percentage of macrophages outside fascicle in all segments of sciatic nerve and within the fascicle in the proximal segment reached its peak on day 3, the percentage of macrophages within the fascicles at the site of injury and distal segments reached the peak later at day 7. In conclusions, accumulation of macrophages outside the nerve fascicles occurs at the beginning of the injury, and then followed later by the accumulation of macrophages within nerve fascicles
Cervical cancer screening coverage in urban and rural areas: its determinants Juminten Saimin; Satrio Wicaksono; . Ashaeryanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018): SUPPLEMENT
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.221 KB) | DOI: 10.19106/JMedScieSup005001201806

Abstract

Cervical cancer is a woman’s health problem that is still widespread throughtout the world, especially in developing country such as Indonesia. The high incidence of cervical cancer related with early detection program. Visual inspection of acetic acid (VIA) is used as an alternative screening method because it is easier, cheaper and effectiveness is not much different from the Pap test. The most participant in urban and rural areas was the age group 31-40 years old, low parity, and first intercourse at ≥ 17 years old. There was asscociation between cervical cancer screening coverage with education level, knowledge and distance of service facilities. There were significant difference of education level (p = 0.000), knowledge (p = 0.000) and distance of service facilities of urban and rural participant (p = 0.000). There was no significant differences in family support of urban and rural participant (p = 0.224).
Factors Affecting the Development of Anxiety in Postmenopausal Women: A CrossSectional Study in Coastal Areas: FaktorFaktor yang Mempengaruhi Terjadinya Kecemasan pada Perempuan Pascamenopause: Suatu Studi Potong Lintang di Daerah Pesisir Juminten Saimin; Satrio Wicaksono; Junuda Junuda; Minarti Minarti
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.747 KB) | DOI: 10.32771/inajog.v6i3.775

Abstract

Objective: To analyze factors associated with anxiety in postmenopausal women. Methods: This study was descriptive analytic with cross-sectional approach conducted in 228 postmenopausal women that aged 50-64 years old in coastal areas of Kendari City. Samples were taken by simple random sampling. The technique of collecting data used questionnaires and the Taylor Manifest Anxiety Scale (T-MAS). Data were analyzed using Chi-square test with a significance value p ï‚£ 0.05. Results: The results showed that 188 respondents (82.4%) had. anxiety. Its most experienced anxiety was aged 50-54 years old (37.7%), low education (96.0%), as housewife (62.7%), low income (91.2%) and lived with a partner (54.4%). There was correlation between anxiety with age (p=0.016), education level (p = 0.009), income (p = 0.011), and residence status (p = 0.029). There was no correlation between anxiety with occupation (p = 0.351). Conclusion: There was a correlation between anxiety in postmenopausal women in coastal areas with age, education level, income, and residence status. Keywords: age, anxiety, education level, income, postmenopausal women, residence status
Socio-Demographic and Nutritional Determinants of Birth Weight in Coastal Areas: Determinan Sosio-demografikdan Gizi yang Berhubungan dengan Berat Badan Lahir Bayi di Daerah Pesisir Juminten Saimin; Amalia N Azizah; Satrio Wicaksono
Indonesian Journal of Obstetrics and Gynecology Volume 7, No. 1 January 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (63.897 KB) | DOI: 10.32771/inajog.v7i1.818

Abstract

Abstract Objective : To identify socio-demographic and nutritional determinant associated with birth weight in coastal areas. Method : A cross sectional study using simple random sampling method. Data of labour in coastal areas of Kendari City was analyzed. Total of 215 women who aterm delivery in Community Health Centre of Mata, Nambo and Abeli on January to December 2016 were included in this study. Birth weight was examined in association with independent variable as maternal age, education, occupation, husband’s job, parity, antenatal care, iron tablets consumption and upper arm circumference. Results : Most participants were aged 20-25 years old, primary education, as housewife, multiparity and husband work as self-employed. There was 8.9% low birth weight in coastal areas. Maternal age, education and ANC visits were significantly associated with birth weight (p < 0.05). Consumption of iron tablets and upper arm circumference were significantly associated with birth weight (p < 0.05). Conclusion :Maternal age, education and ANC visits were socio-demographic determinant that associated with birth weight. Iron tablets consumption and upper arm circumference were nutritional determinant that significantly associated with birth weight. Keywords : age, antenatal care, birth weight, education, iron tablets, upper arm circumference Abstrak Tujuan :Mengidentifikasi determinan sosio-demografik dan gizi yang berhubungan dengan berat badan lahir bayi di daerah pesisir. Metode :Penelitian potong lintangdengan pengambilan sampel secara simple random sampling. Dilakukan analisis terhadap 215 ibu hamil yang melahirkan bayi cukup bulan di wilayah kerja Puskesmas Mata, Nambo dan Abelipada bulan Januari sampai Desember 2016. Varia beli independen berupa usia ibu, tingkat pendidikan, pekerjaan, pekerjaan suami, paritas, antenatal care, konsumsi tablet besi dan ukuran lingkar lengan atas. Hasil :Responden terbanyak berusia 20-25tahun, berpendidikan rendah, bekerja sebagai ibu rumah tangga, multiparitas dan pekerjaan suami wiraswasta. Terdapat8,9% bayi BBLR. Terdapat hubungan yang bermakna antara usia ibu, tingkat pendidikan dan ANC dengan BBL (p < 0.05). Terdapat hubungan yang bermakna antara konsumsi tablet besi dan ukuran LILA dengan BBL (p < 0.05). Kesimpulan :Determinan sosio-demografik yang berhubungan dengan BBL adalah usia, tingkat pendidikan, dan ANC. Sedangkan determinan gizi yang berhubungan dengan BBL adalah konsumsi tablet besi dan ukuran LILA. Kata kunci: ANC, BBL, LILA, pendidikan, tablet besi, usia
Uterine Prolapse in Postmenopausal Women in the Coastal Areas: Prolaps Uteri pada Perempuan Postmenopause di Daerah Pesisir Juminten Saimin; Indria Hafizah; Nina Indriyani; Ashaeryanto; Satrio Wicaksono
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 4 October 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v8i4.1349

Abstract

Objective: To assess the characteristics of postmenopausal women in the coastal areas that experience uterine prolapse.Methods: This was a retrospective descriptive study conducted at Alpha Gynecology Clinic in Kendari. Samplesare cases of uterine prolapse from coastal areas that visited in January to December 2017. Samples were taken by consecutive sampling. The diagnosis of uterine prolapse is based on the Pelvic Organ Prolapse Quantification system. Data is presented with tables and narration.Results: There were 21 respondents who experienced uterine prolapse. Most respondents were aged 61-70 years (42.8%), work as housewives (71.4%), parity more than 4 (85.7%), and duration of menopause >5 years (100.0%). The most common complaint at the fi rst time was a feeling of a lump in the vagina (81.0%), in the third degree of uterine prolapse (57.1%), and accompanied by comorbidities (66.7%). Conclusions: Uterine prolapse in postmenopausal women in the coastal areas was found in housewives, aged 61-70 years, grande-multiparous, and duration of menopause >5 years. The main complaint was felt a lump in the vagina, in the third degree and accompanied by comorbidities. Counselling, information and education regarding symptoms and management of uterine prolapse need to be done.Keywords: coastal areas, postmenopausal women, uterine prolapse.AbstrakTujuan: Mengetahui karakteristik perempuan postmenopause di daerah pesisir yang mengalami prolapsus uteri.Metode: Penelitian ini bersifat deskriptif retrospektif yang dilakukan di Klinik Ginekologi Alfa di Kendari. Sampel adalah kasus prolapse uteri yang berasal dari daerah pesisir yang berkunjung pada bulan Januari sampai Desember 2017. Sampel diambil secara consecutive sampling. Diagnosis prolapsus uteri berdasarkan sistem Pelvic Organ Prolapse Quantification. Data disajikan dalam bentuk tabel dan narasinya.Hasil: Hasil penelitian menunjukkan terdapat 21 responden yang mengalami prolapsus uteri. Responden terbanyak berusia 61-70 tahun (42,8%), pekerjaan sebagai ibu rumah tangga (71,4%), paritas lebih dari 4 (85,7%), dengan lama menopause lebih dari 5 tahun (100,0%). Keluhan yang paling sering dialami pada saat pertama datang adalah terasa ada yang mengganjal di jalan lahir (81,0%), dengan diagnosis prolapsus uteri derajat 3 (57,1%), dan disertai penyakit penyerta (66,7%).Kesimpulan: Prolapsus uteri pada perempuan postmenopause di daerah pesisir ditemukan pada ibu rumah tangga, usia 61-70 tahun, grande multipara, menopause >5 tahun. Keluhan utama terasa ada yang mengganjal di jalan lahir disertai penyakit penyerta, dengan diagnosis prolapse uteri derajat 3. Perlu dilakukan penyuluhan, konseling dan edukasi mengenai gejala dan penatalaksanaan prolapsus uteri.Kata kunci: daerah pesisir, prolaps uteri, perempuan postmenopause.
HUBUNGAN MOTIVASI INTRINSIK TERHADAP PELAKSANAAN PEMBELAJARAN LANGSUNG DI FAKULTAS KEDOKTERAN HALU OLEO UNIVERSITAS KENDARI Ashaeryanto Ashaeryanto; Satrio Wicaksono; Juminten Saimin; Rezki Fitrianti
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol 2, No 2 (2019): Emergency Medicine
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/aimj.v2i2.3958

Abstract

Self-Directed Learning (SDL) is a student-centered learning in which the process and experience of learning are individually regulated and controlled by the student. The implementation of SDL is an interaction of several aspects, including self-motivation, self-control, and self-monitoring skills. Students with strong motivation in the learning process will have more consistency in implementing the SDL. Inner self-motivation will give better impacts than that obtained from the outside. This study aimed to analyze the correlation of intrinsic motivation to SDL implementation in the Faculty of Medicine of Halu Oleo University. The study was quantitative research using a cross-sectional design. Subjects were 91 sophomores of the Faculty of Medicine of Halu Oleo University (UHO). Data were collected using a total sampling method. SDL implementation and intrinsic motivation were measured using Self-Directed Learning Readiness Scale (SDLRS) and Intrinsic Motivation Inventory (IMI) questionnaires, respectively. Data were statistically analyzed using Pearson’s correlation. Second-year of medical students of UHO showed a high intrinsic motivation and SDL implementation. Students with high intrinsic motivation were found to apply high implementation of SDL. Moreover, students with moderate intrinsic motivation also showed high implementation of SDL. There is a significant correlation between intrinsic motivation to SDL implementation among medical students of UHO. Further research is required to investigate other factors that affect the SDL implementation of medical students.
Neuroprotective Effect of Brain-Derived Neurotrophic Factor (BDNF) on Cerebral Infarct Volume and Clinical Severity of Acute Ischemic Stroke Satrio Wicaksono; Andi Kurnia Bintang; Muhammad Akbar; Muhammad Yunus Amran; Cahyono Kaelan; Isra Wahid
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 1 (2024): Desember
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v12i1.45

Abstract

ABSTRACT Background: Brain-Derived Neurotrophic Factor (BDNF) plays a crucial role in protecting nerves following ischemic stroke. The neuroprotective effects of BDNF on cerebral infarct volume and clinical severity after ischemic stroke need to be further studied in-depth. Purpose(s): The purpose of this study is to understanding the relationship between BDNF levels, cerebral infarct volume, and the severity of clinical conditions in acute ischemic stroke patients. Methods: This study is an observational nalytical research with a cross-sectional design. A total of 30 individuals who meet the inclusion criteria were included as samples. Cerebral infarct volume was measured using non-contrast head CT scans with the Broderick formulation, and clinical severity was assessed using the National Institutes of Health Stroke Scale (NIHSS). The collected data were then analyzed using statistical tests. Results: There is a significant relationship between serum BDNF levels and cerebral infarct volume with a p-value of 0.004 and a correlation coefficient (r) of -0.509. Similarly, a significant relationship exists between serum BDNF levels and NIHSS with a p-value of 0.042 and a correlation coefficient (r) of -0.374. Conclusion: There is a negative correlation between serum BDNF levels and cerebral infarct volume in acute ischemic stroke patients, as well as a negative correlation between serum BDNF levels and clinical severity in acute ischemic stroke patients. Keywords: BDNF; Infarct Cerebri Volume; NIHSS
Peningkatan Pengetahuan dan Keterampilan Penanganan Low Back Pain bagi Kader Kesehatan di Puskesmas Kecamatan Kendari Barat, Kota Kendari Sulawesi Tenggara Tahun 2025 [Enhancing Knowledge and Skills in Managing Low Back Pain for Health Fasililator at the Kendari Barat District Community Health Center, Kendari City, Southeast Sulawesi in 2025] Satrio Wicaksono; Sufiah Asri Mulyawati; Ashaeryanto Ashaeryanto; Muhammad Rustam H Noertika; Mariana Asmaningdiah; Dewinta Nur Alvionita; Lindia Aksa; Izur Fisabilillah Aminuddin
Indonesia Berdaya Vol. 7 No. 1 (2026)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.20261415

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Low back pain (LBP) is one of the most common musculoskeletal disorders worldwide, with a global prevalence of 60–80% among adults. This condition results in limitations of daily activities, decreased productivity, and reduced quality of life. In Indonesia, LBP is frequently reported among both productive and elderly age groups, with major risk factors including non-ergonomic working postures, insufficient physical activity, and degenerative processes. In Kendari Barat District, LBP cases are often encountered at community health centers , particularly among individuals with diverse occupations such as office workers, traders, and laborers. These jobs often involve repetitive physical activity or prolonged static postures, highlighting the need for stronger promotive and preventive interventions at the community level.The purpose of this community service program is to strengthen the capacity of health fasilitators in understanding, preventing, and managing LBP through education, ergonomic training, and stretching exercises. The methods applied include interactive counseling, practical simulations, and cadre mentoring at the Kendari Barat Community Health Center. A total of 60 health cadres participating in this activity are expected to contribute by providing education to the community in their respective environments.                                                              Abstrak. Low back pain (LBP) merupakan salah satu gangguan muskuloskeletal dengan prevalensi global tinggi, yaitu 60–80% pada orang dewasa, dan berdampak pada keterbatasan aktivitas, penurunan produktivitas, serta kualitas hidup. Di Indonesia, keluhan LBP banyak dijumpai pada kelompok usia produktif maupun lanjut usia, dengan faktor risiko utama berupa postur kerja tidak ergonomis, kurangnya aktivitas fisik, serta proses degeneratif. Di Kecamatan Kendari Barat, kasus LBP sering ditemukan di Puskesmas, terutama pada masyarakat dengan variasi pekerjaan seperti pegawai kantoran, pedagang, dan buruh. Kondisi ini menegaskan perlunya intervensi promotif dan preventif yang lebih kuat di tingkat komunitas. Tujuan dari program pengabdian masyarakat ini adalah meningkatkan kapasitas kader kesehatan dalam memahami, mencegah, dan menangani LBP secara sederhana melalui edukasi, pelatihan ergonomi, serta latihan peregangan. Metode yang digunakan meliputi penyuluhan interaktif, simulasi praktik, dan pendampingan kader di Puskesmas Kecamatan Kendari Barat. Sebanyak 60 kader kesehatan yang mengikuti kegiatan ini diharapkan mampu memberikan berkontribureka dalam memberikan edukasi kepada Masyarakat dilingkungan mereka masing-masing.
Edukasi dan Pemeriksaan Kesehatan untuk Meningkatkan Kesadaran Masyarakat tentang Stroke di Wilayah Pesisir Toronipa, Soropia Ashaeryanto; Sufiah Asri Mulyawati; Satrio Wicaksono; Sulastrianah; Muhammad Rustam HN; Yenti Purnamasari; Aan Maulana; Izur Fisabilillah Aminudin
Jurnal Pengabdian Meambo Vol. 4 No. 1 (2025): Jurnal Pengabdian Kepada Masyarakat MEAMBO
Publisher : PROMISE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56742/jpm.v4i1.103

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Stroke menjadi penyebab utama kematian di Indonesia, termasuk di Kelurahan Toronipa, Soropia. Rendahnya pemahaman masyarakat tentang faktor risiko seperti hipertensi dan gaya hidup tidak sehat diperburuk oleh faktor geografis dan keterbatasan akses layanan kesehatan. Pengabdian ini bertujuan untuk meningkatkan kesadaran masyarakat terhadap pencegahan stroke secara efektif. Kegiatan dilaksanakan tanggal 20 November 2024, di Kantor Kelurahan Toronipa. Pendekatan berbasis penyuluhan, edukasi, dan pemeriksaan kesehatan gratis, melibatkan tenaga medis, kader, dan tokoh masyarakat. Penyuluhan mencakup bahaya stroke, faktor risiko, dan deteksi gejala awal dengan metode FAST. Pemeriksaan kesehatan meliputi pengukuran tekanan darah, gula darah, kolesterol, dan konsultasi medis. Peserta berjumlah 50 orang. Hasil pengabdian menunjukkan bahwa mayoritas responden perempuan (74%), dengan risiko meningkat pasca-menopause. Kelompok dewasa (42%) dan pra lansia (38%) menjadi fokus pencegahan dini, sementara lansia (20%) memerlukan manajemen penyakit kronis. Faktor risiko utama meliputi kolesterol tinggi (38%), diabetes (10%), dan hipertensi (54%). Edukasi gaya hidup sehat efektif menurunkan risiko. Kesimpulan pengabdian adalah bahwa meningkatkan kesadaran pencegahan stroke melalui edukasi, deteksi dini, dan gaya hidup sehat, dengan dampak positif jangka panjang.
Workshop Bantuan Hidup Dasar dan Penggunaan AED Petugas Pintu Masuk Pelabuhan dan Bandara Asmarani; Nina Indriyani Nasruddin; Arimaswati; Satrio Wicaksono; Sri Susanty
Jurnal Pengabdian Meambo Vol. 4 No. 1 (2025): Jurnal Pengabdian Kepada Masyarakat MEAMBO
Publisher : PROMISE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56742/jpm.v4i1.109

Abstract

Pelabuhan dan bandara merupakan lokasi strategis dengan intensitas lalu lintas manusia yang tinggi, sehingga membutuhkan petugas yang terlatih dalam Bantuan Hidup Dasar (BHD) dan penggunaan Automated External Defibrillator (AED) untuk menangani keadaan darurat medis. Tujuan pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan dan keterampilan petugas pintu masuk pelabuhan dan bandara dalam memberikan pertolongan pertama yang cepat dan tepat. Metode pengabdian dilakukan dalam bentuk workshop di Gedung Wilker Bandara, Konawe Selatan, yang melibatkan teori, praktik langsung, simulasi, serta evaluasi melalui pretest dan posttest. Peserta merupakan petugas dari Balai Karantina Kesehatan Kelas 1 Kendari. Hasil pengabdian menunjukkan terdapat peningkatan signifikan dalam skor pengetahuan dan keterampilan peserta. Pada pengetahuan, skor 80 meningkat dari 0% (pretest) menjadi 33,3% (posttest). Pada keterampilan, skor 80 meningkat dari 0% (pretest) menjadi 40% (posttest). Kesimpulan pengabdian adalah efektif dalam meningkatkan pengetahuan dan keterampilan peserta terkait BHD dan penggunaan AED, sehingga dapat meningkatkan kesiapan mereka dalam menghadapi situasi darurat medis.