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All Journal Indonesian Journal of Geography Journal of Marine Research Jurnal Kelautan Tropis UNEJ e-Proceeding Jurnal Pertanian Terpadu Jurnal Wiyata : Penelitian Sains dan Kesehatan Indonesian Journal of Chemistry Jurnal Kelautan Nasional Science Midwifery Journal of Pharmaceutical Care Anwar Medika Jurnal Riset Kelautan Tropis (Journal Of Tropical Marine Research) (J-Tropimar) Environmental Pollution Journal Jurnal Riset Kelautan Tropis (J-Tropimar) Journal of Pharmacy Science and Technology
Mahmiah
Program Studi Oseanografi, Fakultas Teknik Dan Ilmu Kelautan, Universitas Hang Tuah
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Journal of Pharmacy Science and Technology

 1 
UJI DAYA ADSORPSI ARANG AKTIF DARI TUMBUHAN MANGROVE Avicennia marina Rina Andayani; Mahmiah
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Voume 1 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Indonesia has the largest mangrove forest in the world. In addition, Indonesia is also a country with the largest number of mangrove species in the world. This creates a huge potential in the utilization of mangroves in many areas of life, one of them is in the health field. Where, the majority of the plants widely used in the health sector are land plants. Charcoal has been used in the field of health for thousands years. Charcoal generally utilized in the field of health in the form of activated charcoal. Activated charcoal or activated carbon is charcoal that has been through an activation process, chemical or physical. Activated charcoal can be made from any substance containing carbon. Given that wood is a renewable raw material, the use of wood as a material manufacture of activated charcoal is recommended. In this study, the material to be used in the manufacture of activated charcoal was wood from the mangrove plant Avicennia marina. The activation process used in this study was chemical activation using ZnCl2. This study included three stages: (1) carbonization; (2) activation of charcoal; (3) adsorption test of activated charcoal. The results showed that the higher the ratio of ZnCl2 mass / charcoal mass used in the activation process, the higher the adsorption capacity of activated charcoal produced. The highest % removal of CH3COOH was obtained at a ratio of ZnCl2 mass/charcoal mass of 2 which was 30.73%.
SKRINING FITOKIMIA DAN UJI POTENSI ANTIKANKER EKSTRAK METANOL KULIT BATANG (Rhizophora mucronata (Lamk.)) MENGGUNAKAN METODE BSLT (Brine Shrimp Lethality Test) Asniyah, Asniyah; Mahmiah, Mahmiah; Sudjarwo, Giftania Wardani
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.101

Abstract

Cancer is one of the leading causes of death in the world. The main therapies for cancer include surgery, chemotherapy, radiotherapy. However, the use of chemotherapy drugs can cause side effects such as hair loss, bone marrow suppression, drug resistance. Based on these side effects, this study conducted research on natural ingredients as an alternative to cancer treatment. Rhizophora mucronata can be used as an anticancer, where people in coastal areas or around mangrove forests use mangroves as medicinal plants, and are believed to have minimal side effects so that they can be developed as traditional medicines. In this study, analysis of phytochemical screening and anticancer potential tests of methanol extract of Rhizophora mucronata stem bark was carried out from Pamurbaya, Surabaya, East Java. In this study, the BSLT (Brine Shrimp Lethality Test) method was used to test the anticancer potential with the LC50 (Letal Concentration) value as a parameter. The results of phytochemical screening of the methanol extract of Rhizophora mucronata stem bark contain tannins, saponins, alkaloids, steroids, flavonoids, anthraquinones and polyphenols and have anticancer potential with an LC50 value of 120.8656 ppm which falls into the toxic category.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK AKAR BAKAU HITAM (Rhizophora mucronata (Lamk.)) DENGAN METODE DPPH (2,2-diphenyl-1-picrylhydrazyl) Sulistiorini, Indah; Mahmiah, Mahmiah; Sudjarwo, Giftania Wardan
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.102

Abstract

Indonesia is a country that has a variety of marine ecosystems that have a lot of potential, one of which is mangroves. Rhizophora mucronata is a species in the mangrove ecosystem in Indonesia. Rhizophora mucronata or black mangroves are plants that contain various kinds of compounds. Antioxidants play an important role in the prevention of degenerative diseases. This research is motivated by the presence of carcinogenic dangers caused by consuming synthetic antioxidants at high doses synthetic antioxidants can function as prooxidants which can increase oxidative stress and damage body cells, so it wants to explore the natural antioxidant potential of Rhizophora mucronata. Rhizophora mucronata root was chosen in this study because no one has examined the potential of this plant that grows in the Pamurbaya area, Surabaya - East Java as an antioxidant. This study aims to determine the content of secondary metabolites and antioxidant activity of the root extract of Rhizophora mucronata. In this study, the antioxidant activity test used the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results showed that the antioxidant activity of the methanol extract of Rhizophora mucronata root had very weak antioxidant activity with an IC50 value of 2604.56 ppm. The antioxidant potential of the methanol extract of Rhizophora mucronata root has an IC value of 50 with a very weak antioxidant intensity
Co-Authors Alifia Putri Rahmadani Alifia Rizky Novitasari Andriyani, Febby Asniyah, Asniyah Aulia Putri Apsari Chairrany, Bibi Dandy Aditya Permana Engki Andri Kisnarti Fachrani Vebranti Millenia Farilla Intan Kurnia Rizky Fransiska Yuliasara Giftania Wardani Sudjarwo Gilmawan, Giman Giman Giman Giman Heronima Natalia Sunur Hilda Ziya Abiyana Ika Pibria Ningrum Jannatus Mega Blezensky Juniar, Kiki Marcy Valerie Anggraini Megawati Mutiara Gusti Mery Nova Sari Mulyadi Tanjung Nani Wijayanti Nanik Siti Aminah Nirmala Idha Wijaya Nirmalasari Idha Wijaya Nirmalasari Idha Wijaya Nirmalasari Idha Wijaya Nor Sa'adah Nor Sa'adah Nor Sa’adah Nor Sa’adah Pramudita Riwanti Ramanda Reza Aldiano Rheamyta Carissa Siregar Rheamyta Carissa Siregar Rina Andayani Rudi Siap Bintoro Rudi Siap Bintoro Rudi Siap Bintoro Sarah Nur Qowiyah Sari, Aprilyas Kusuma Amalia Sari, Mery Nova Sa’adah, Nor Serdian Pinaris Rama Sudjarwo, Giftania Wardan Sulistiorini, Indah Tiento Rifqy Pribadi Triski Aulia Rofilla Viv Djanat Prasita Yuliasara, Fransiska