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All Journal Prosiding Seminar Biologi Jurnal Pendidikan Indonesia Prosiding Seminar Biologi Jurnal Pendidikan Biologi Indonesia Jurnal SOLMA Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Bioma : Jurnal Biologi Indonesia Biota Indonesian Journal of Dental Medicine Journal of Community Service and Empowerment Proceeding Biology Education Conference
Nurul Mahmudati
Fakultas Keguruan Dan Ilmu Pendidikan Universitas Muhammadiyah Malang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Antibacterial potential of robusta coffee beans (Coffea canephora var. robusta): A review Irmawati, Anis; Nurmalia, Salsabila; Rahmaputri, Annisa; Mahmudati, Nurul; Noman, Labib; Balqis, Noor Faizah
Indonesian Journal of Dental Medicine Vol. 9 No. 1 (2026): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v9i1.2026.48-55

Abstract

Background: A gram-positive bacterium, Staphylococcus aureus, is known for causing infections in areas like the skin, lungs, and mouth, and has spurred interest in natural remedies due to growing antibiotic resistance. This has led researchers to explore alternatives from sources such as Robusta coffee beans (Coffea canephora var. robusta), which contain potent bioactive substances. Purpose: The review aims to elaborate on the effectiveness of Robusta coffee beans in combating pathogens like S. aureus and to pinpoint the key ingredients contributing to their antibacterial activity. Reviews: Research indicates that Robusta coffee beans are rich in active elements (caffeine, chlorogenic acid, caffeic acid, and trigonelline), all of which demonstrate antimicrobial and antivirulence capabilities. These compounds work by compromising the integrity of the bacterial cell membrane, blocking protein production, and weakening the cell wall, ultimately resulting in cell breakdown. Chlorogenic acid, the most abundant of these, shows both inhibitory and lethal effects on bacteria. S. aureus is notorious for building tolerance to multiple antibiotics, complicating treatment. This challenge stems from its harmful traits, notably Panton-Valentine Leukocidin (PVL), which boosts its danger by destroying leukocytes and triggering tissue necrosis. Conclusion: Robusta coffee beans (C. canephora var. robusta) have great potential antibacterial activity attributed to their bioactive compounds, which inhibit pathogens such as S. aureus, Escherichia coli, Staphylococcus epidermidis, and Salmonella typhi. These findings suggest that robusta coffee beans may serve as a viable source for developing alternative natural antibacterial formulations, particularly against S. aureus associated infections.
Co-Authors Ahmad Fauzi Ambarwati, Anjar Rizki Aminullah, Yusron Andri Rudi Yanto Anis Irmawati Arista Mutiara Risa Balqis, Noor Faizah Darwis Husain Darwis Husain, Darwis Dewi Endah Sari Dwi Marga Lestari Fuad Jaya Miharja Husamah Husamah I Gusti Bagus Wiksuana Iin Hindun Iin Hindun Iman, Vikry Nurul Iman Iswanto Iswanto Iswanto Iswanto Latifah, Roimil Lise Chamisijatin Noman, Labib Nurmalia, Salsabila Nurwidodo Nurwidodo Nurwidodo Nurwidodo Nurwidodo, Nurwidodo Rahmaputri, Annisa Rr. Eko Susetyarini Sari, Dewi Endah Siti Zaenab Siti Zaenab Sukarsono . Sukarsono . Sukarsono Sukarsono Yanto, Andri Rudi Yuni Pantiwati Yusron Aminullah