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All Journal Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Universa Medicina Parafrase: Jurnal Kajian Kebahasaan dan Kesastraan Molekul: Jurnal Ilmiah Kimia BALABA (JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA) National Journal of Occupational Health and Safety Medical and Health Journal Biomedika

Yudhi Wibowo

Department of Public Health and Community Medicine Faculty of Medicine Jenderal Soedirman University

Author-ID : 3160210

Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Veterinary

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Incidence of malaria is clustered and buffers around plantations: a spatial analysis Yudhi Wibowo; Agung Saprasetya Dwi Laksana; Joko Mulyanto; Madya Ardi Wicaksono; Agus Y Purnomo
Universa Medicina Vol. 34 No. 2 (2015)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.138-148

BackgroundMalaria is re-emerging because of imported cases and the presence of potential vectors that can transmit and spread malaria. Malaria is a health problem in Banyumas District. Mapping the spread of infectious diseases is epidemiologically important. The purpose of this study was to determine the relationship between the variables and the epidemiology of malaria that were spatially modeled using the geographic information system (GIS).MethodsThis was a case-control study with ratio of 1:1. Cases were malaria-positive patients and controls were people without malaria, as diagnosed by microscopic examination. Minimum sample size was 139 per group and total sample size was 282 people. Chi-square was used to test the relationship between the variables, and GIS modeling to determine the spatial distribution of malaria cases.ResultsThere were significant relationships between level of income below minimum wage, not using mosquito nets, not using wire netting, not using insect repellents, habit of going out at night, history of malaria, cattle sheds not located between woods and residential area, history of going to endemic areas, residence at distances <1000 m from plantations, bushes, swamps and puddles, with incidence of confirmed malaria (p<0.001). The group of cases living <1000 meters from plantations numbered 141 (100%).ConclusionsMalaria incidence is clustered and buffers around plantations at <1000 m. Malaria hot spots are displayed as risk maps that are useful for monitoring and spatial targeting of prevention and control measures against the disease.

TEKS BERITA KONFLIK PEKERJA PT FREEPORT INDONESIA: ANALISIS WACANA KRITIS FOUCAULT Yudhi Hari Wibowo
PARAFRASE : Jurnal Kajian Kebahasaan & Kesastraan Vol 13 No 01 (2013)
Publisher : Universitas 17 Agustus 1945 Surabaya

ABSTRACT. This study reports a critical discourse analysis on news reports on labour conflicts at PT Freeport Indonesia. The study adopts Foucaultâ€™s approaches to critical discourse analysis. According to Foucault, a discourse is an organized language constructing social practice in order to change or to maintain power domination. In this perspective, language is recognized as both the power and the instrument. The analysis article examines the news on the PT Freeport Indonesia labour conflict from the viewpoints of topic, data, theme identification, the search of hidden discourse elements, the search of meaning relationship among the discourse elements, the contextualization of the discourse elements of the power-knowledge network. The results show that the difference of the wages based on biopolical practices under the basis of race discrimination among the Freeport labours triggered the horizontal conflict that was settled under the control of the company. The study also found an indication of a practice of panoptic. This control was effective to settle the conflict because it demanded the obediance productivities on the side of the labours. However, this kind of control camuflased the reality of the Freeportâ€™s massive profit gaining, Freeportâ€™s exploration that damaged the environment, and Timika peopleâ€™s living in poverty.Â Â Key words: critical discourse analysis, race discrimination, biopolitic, hidden elements, knowledge power Â

PENYELIDIKAN KEJADIAN LUAR BIASA CAMPAK DI TK NUR JAMIL DESA CEMANI KECAMATAN GROGOL KABUPATEN SUKOHARJO PROPINSI JAWA TENGAH TAHUN 2011 Wibowo Y; Rahayujati TB; Wisnuwijoyo AP
BALABA: JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA Volume 8 Nomor 1 Juni 2012
Publisher : Balai Penelitian dan Pengembangan Kesehatan Banjarnegara Badan Litbangkes Kemenkes RI

Background: On Wednesday, July 27, 2011, District Health Office Sukoharjo received a report from the health center Sukoharjo Grogol that has been an increase in clinical cases of measles in NJ kindergarten in Cemani Village. To ascertain whether there has been an measles outbreak in kindergarten NJ, it is necessary to the investigation of the outbreak. Methods: Regional tracking outbreaks of measles cases is mainly done in kindergarten NJ, Cemani. Criteria and clinical measles cases is determinated by the diagnosis with laboratory tests and measles IgM positive cases in connection with the case of the epidemiology of measles IgM positive. This investigation is an observational analytic approach to the design of case-control study. Analytic form of univariate and bivariate test using 2x2 table so as to obtain the Odds Ratio (OR) and p-value. Results: Of the 37 clinical measles cases, 100% had fever, rash with cough/cold and 81.1% of cases with symptomps of conjunctivitis. Whole blood samples showed positive IgM measles, measles outbreaks proved to be a definite. Curve shape is propagated epidemic curve, showing the spread of measles disease from person to person directly. Most cases of infection in school (47.9%), hystory of household contact (26.8%), and neighbors/peer groups (23.9%). In the cases, 54.1% had no history of immunization against measles and 83.8% had no history of measles. In contrast to the controls, 91.1% had a history of measles immunization. Related variables are statistically significant are not immunized against measles with OR 13.3 (95% CI, 3.471 to 51.223, p = 0.000), did not get sick with Vitamine A before OR = 8.4 (95% CI, 1.728 to 40.883; p = 0.003) and no history of previous measles OR = 0.456 (95% CI, 0.352 to 0.591, p = 0.025). Conclusions: The outbreak that occured in NJ TK due to the confirmation of positive measles IgM measles. Attack Rate of both boys and girls in NJ highest in the age group 4 to 4.5 years (TK 0 small) are respectively 31.4% and 32.1%. Mode of transmission is mainly through contact with people at school. Risk factors for incidence of measles is not immunized and did not receive Vitamin A before illness.

No Acute Toxicity Tests of Purwoceng (Pimpinella pruatjan Molk.) Ethanolic Extract on Male Albino Rat by Determined Hepatorenal Function Test and Histopathology Fitranto Arjadi; Dhadhang Wahyu Kurniawan; Yudhi Wibowo; Wahyu Siswandari; Lantip Rujito
Molekul Vol 14, No 2 (2019)
Publisher : Universitas Jenderal Soedirman

Pimpinella pruatjan Molkis a local indegineuos plant speciescommonly used aphrodisiac.This studywas performed to analyze the effect of acute administration of purwoceng (Pimpinella pruatjan Molk.) roots ethanol extract to liver and kidney histological damagein rats. The study used an experimental approachusing post test only with control group design. Rats were randomly divided into five groups; 3 rats in each group. Group A as a control group received aquadest, group B, C, D, and E were given purwoceng roots ethanol extract dose of 5 mg/kgBW, 50 mg/kgBW, 300 mg/kgBW, and 2000 mg/kgBW respectively.Liver histological damage was assessed by a modification of the Roenigk score, whereaskidney damage was by the semiquantitative scoring of proximal tubular necrosis. UV test was used to quantify the AST and ALT levels, the measurement of blood urea levels was using the Urease-GLDH method, and Jaffe methodwas used to access the creatinine levels.Kruskal-Wallis test showed that liver and kidney histologicalparameterswere not significantly affected, as well as theblood urea and creatinine levels (p>0.05).Meanwhile,ALT level wasonly parameters which showed the significant test (p <0.05)among groups. Study concluded that the liver and kidney histological appearance, AST, blood urea, and creatinine levels in the male albino rat were not significantly affected by acute administration of Purwoceng roots in various dosesbut the ALT level was significantly affected

Differences in Levels of Prostate Specific Antigen and Insulin-like Growth Factor 1 in GSTP1 Gene Polymorphism among Workers Nendyah Roestijawati; Yudhi Wibowo; Tri Lestari
National Journal of Occupational Health and Safety Vol 1, No 01 (2020)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Indonesia

Cadmium (Cd) is classified as a carcinogen in humans (IA). In addition to causing lung cancer, the incidence of prostate cancer due to Cd exposure based on epidemiological research has also increased. This study aims to identify the GSTP1 genotypic frequency distribution and its correlation with PSA and IGF-1 levels in Cd exposed and unexposed workers. The research design used was cross sectional in 23 exposed groups (weld workers) and 40 unexposed groups (office employees) with a total of 63 people. The measurement of PSA and IGF-1 levels was carried out using the ELISA method and identification of the GSTP1 gene polymorphism using the PCR-RFLP method. Data analysis using Mann-Whitney and Spearman correlation test. The results showed that there was a relationship between PSA levels and IGF1 (p <0.01, r = 0.515) in all subjects. The results of identification of GSTP1 gene polymorphism were obtained as ile/ile genotypes as much as 30.2% and ile/val as much as 69.8%. There were no differences in PSA and IGF1 levels between ile/ile and ile/val genotypes (p> 0.05). There was a relationship between PSA and IGF1 (p <0.01, r = 0.569) in the group of Cd exposed workers and no differences in PSA and IGF1 levels between the ile/ile and ile/val genotypes (p> 0.05). There was a relationship between PSA and IGF1 (p <0.05, r = 0.342) in the unexposed group of workers and no differences in PSA and IGF1 levels between ile/ile and ile/val genotype (p>Â 0.05).

Combination of Vitamin C and E Improves Spermatogenesis of White Male Rat Model of Paradoxical Sleep Deprivation Stress Fitranto Arjadi; Mustofa Mustofa; Yudhi Wibowo; Nur Signa Aini Gumilas; Dzicky Rifqi Fuadi
Jurnal Kedokteran Brawijaya Vol. 32 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.01.2

Paradoxical Sleep Deprivation (PSD) elevates glucocorticoid and Reactive Oxygen Species (ROS) levels that cause oxidative stress, trigger spermatogenic cells damage, and reduce the number of sertoli cells. Vitamin C and E are antioxidants that could prevent spermatogenesis damage by preventing free radical formation. The study aimed to determine the effect of single and combined doses of vitamin C and E in improving spermatogenesis of white male rats (Rattus norvegicus) model of PSD. This is experimental research with post-test only and control group design on 28 white male rats distributed into four groups, i.e. group I (control, PSD), group II (PSD+vitamin C), group III (PSD+vitamin E), and group IV (PSD+a combination of vitamin C and E). Testicular preparations were stained using Hematoxylin-Eosin staining, quantitative scores of spermatogenic cells were measured using the Johnsen method, and the number of sertoli cells was counted in 10 seminiferous tubules in each of the three testicular sections. Group I has the lowest mean of Johnsen score (5.27±0.28), and group IV has the highest mean score (8.95±0.62), while the Mann-Whitney test showed a significant difference (p<0.05) between group II, III and IV compared to group I (control group). Mean sertoli cells number of group I is the lowest (10.66±1.04), and group IV has the highest sertoli cells number. The post-hoc LSD test showed a significant difference (p<0.05) between group IV and the other groups. Thus, the combination of vitamins C and E improves Johnsen score and sertoli cells number of male rats (Rattus norvegicus) experiencing PSD.

THE EFFECT OF USING THE VISITING PATIENT APPLICATION ON THE STRESS LEVEL OF INPATIENTS AT MARGONO SOEKARJO HOSPITAL Hasnah Mutfii; Wahyudin Wahyudin; Lily Kusumawati Burkon; Yudhi Wibowo; Thianti Sylviningrum
Medical and Health Journal Vol 2 No 1 (2022): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Latar belakang: Stres adalah perasaan psikologis akibat adanya tekanan mental dan dapat memberi respon negatif terhadap kesehatan. Stres dapat berkurang dengan adanya penambahan pengetahuan melalui suatu informasi dan edukasi yang disampaikan dari media aplikasi. Aplikasi visiting patient adalah aplikasi berbasis android berisi tentang keutamaan orang yang sedang sakit. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan aplikasi visiting patient terhadap tingkat stres pasien rawat inap RS Margono Soekarjo. Metode: Penelitian ini menggunakan jenis kuantitatif quasi experimental dengan rancangan penelitian pre and post-test with control group design. Teknik pengambilan data secara non random sampling dengan pendekatan consecutive sampling. Jumlah responden 24 kontrol dan 24 intervensi. Pengukuran tingkat stres menggunakan kuesioner Depression and Anxiety Stress Scale (DASS) 21. Hasil: Rerata tingkat stres pre-test pada kelompok kontrol 9.67 dan pada kelompok intervensi 11.92, sedangkan rerata post-test pada kelompok kontrol 10.67 dan pada kelompok intervensi 10.25. Hasil uji Dependent T-Test kelompok intervensi didapatkan p=0.069 (p>0.05) yang berarti tidak ada perbedaan yang bermakna pada kelompok intervensi, sedangkan kelompok kontrol didapatkan p=0.037 (p<0.05) yang berarti ada perbedaan yang bermakna pada kelompok kontrol. Hasil uji Independent T-Test didapatkan p=0.796 (p>0.05) yang berarti tidak ada perbedaan yang bermakna pada kelompok intervensi dan kontrol. Kesimpulan: Penggunaan aplikasi visiting patient tidak mempengaruhi tingkat stres pasien rawat inap di RS Margono Soekarjo, tetapi hanya menambah pengetahuan pasien yang setidaknya mampu merubah sikap dan pola pikir.

DISTRIBUSI SPASIAL KUALITAS AIR TANAH DAN DESKRIPSI PENYAKIT YANG BERKAITAN DENGAN AIR DI DESA BRINGKENG, KECAMATAN KAWUNGANTEN, KABUPATEN CILACAP Siti Munfiah; Hajid Rahmadianto Mardihusodo; Tirta Wardana; Yudhi Wibowo; Joko Mulyanto
Medical and Health Journal Vol 2 No 2 (2023): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Access to clean water is fundamental for the population health, but for many rural and remote areas in Indonesia include Cilacap Regency those accesses are still limited. Furthermore, studies that assess the water quality in remote and rural areas in Indonesia are still lacking. Most of the people in Cilacap regency use dug wells and ponds as sources of clean water. Preliminary observations indicate that well and pond water smells fishy, reddish-yellow, or brownish. This condition indicates high iron levels. The test results showed that the iron content exceeded the standard in the pond in Sumbereja Hamlet, RT 03 RW 02, which was 9.8 mg/l (standard quality of 1 mg/l). This study aims to determine the spatial distribution of the water quality and the health-related problems in the rural areas of Cilacap Regency, Central Java, Indonesia. This was a descriptive observational study with a cross-sectional approach. We purposely sampled 40 wells and ponds located in Bringkeng Village, Cilacap Regency, Indonesia and assess the water quality by measuring the level. The results showed the lowest and the highest level of TDS (125.90-5090 mg/l), color (40 -2047 TCU), iron (0.16-6.45 mg/l), manganese (<0.1- 3.61 mg/l). Health problems experienced by respondents and or their families during the last three months, namely 3 people with diarrhea, 7 people with diabetes, 12 people with gout arthritis, 10 people with hypertension, 1 person with nervous system disorders, and 7 people with dry skin disorders/scaly. All dug wells and ponds did not meet the quality standards based on TDS, color, iron, and manganese levels. Water from dug wells and ponds needs special treatment to obtain water that is suitable for hygiene and sanitation purposes.

The Levels of Cholinesterase Enzyme and Hemoglobin in Linggasari Villageâ€™s Farmers Siti Munfiah; Yudhi Wibowo; Octavia Permata Sari; Diah Krisnansari; Muhammad Zaenuri Syamsu Hidayat
Jurnal Kesehatan Masyarakat Vol 18, No 4 (2023)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v18i4.40451

Farmers in Linggasari Village often mix pesticides, did not use pesticides that follow the dose, did not use PPE completely, eat, drink or smoke did not clean themselves after spraying. Some types of pesticides can reduce cholinesterase enzyme and hemoglobin levels. The study aimed to analyze the factors that correlated with cholinesterase enzyme and hemoglobin levels of spraying farmers. This was a cross-sectional study conducted from March to April 2022. The population of this study was all farmers who use pesticides, as many as 30 farmers qualify the inclusion criteria, namely male spraying farmers aged over 18 years, the maximum last contact time with pesticides was two months before the study was conducted. The independent variables were age, BMI, working period, frequency of spraying, duration of spraying, and PPE usage score. The dependent variables included cholinesterase and hemoglobin levels. Bivariate analysis was assessed with Pearson Correlation Test or Spearman Correlation Test, while multivariate analysis used linear regression. The results showed that age (p=0,032, r=0,391) and BMI (p=0,036, r= 0,385) correlated with cholinesterase enzyme, and age (p=0,000, r=0,615) correlated with farmers' hemoglobin levels. The results of multivariate analysis that the most influential factor on cholinesterase enzyme and hemoglobin levels was age.

PERBEDAAN KARAKTERISTIK PEKERJA DAN BIOMARKER PAPARAN LINGKUNGAN KERJA PADA PEKERJA BENGKEL LAS DAN KANTOR Nendyah Roestijawati; MM Rudi Prihatno; M. Zaenuri Syamsu Hidayat; Yudhi Wibowo; Diah Krisnansari
Biomedika Vol 15, No 2 (2023): Biomedika Agustus 2023
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v15i2.3313

ABSTRACT Occupational diseases are caused by the interaction of workers, workload, and work environment factors. This study aims to determine the correlation of worker factors with biomarkers of occupational exposure MT1a, GSTp1, and PSA. The research design used was comparative cross-sectional. The research subjects were 30 welding workers and 30 administrative office employees who were taken by purposive sampling. The variables studied were worker factors such as age and BMI, levels of the enzyme GSTp1, MT1a and PSA. Measurement of GSTp1, MT1a, and PSA in blood was performed using the sandwich ELISA method. Data analysis was performed using the Mann-Whitney test. The results of the study found that there were significant differences in age, BMI, and PSA levels in the two groups. There is no differences in GSTp1 and MT1a level between groups. We concluded that the PSA levels of the group of office workers were higher than those of the group of welding workshop workers, perhaps because the average age was older. ABSTRAK Penyakit akibat kerja disebabkan oleh adanya interaksi faktor pekerja, pekerjaan dan lingkungan kerja. Penelitian bertujuan mengetahui perbedaan karakteristik dan biomarker paparan lingkungan kerja seperti: MT1a, GSTp1 dan PSA antara pekerja bengkel las dan pekerja kantor administrasi. Desain penelitian yang digunakan adalah cross sectional. Subyek penelitian adalah 30 orang pekerja bengkel las dan 30 orang pekerja kantor administrasi yang diambil secara purposive sampling. Variabel yang diteliti adalah factor pekerja berupa usia dan IMT, kadar enzim GSTp1, MT1a dan PSA. Pengukuran GSTp1, MT1a dan PSA dalam darah dilakukan menggunakan metode ELISA sandwich. Analisis data dilakukan dengan uji Mann-Whitney. Hasil penelitian menunjukkan adanya perbedaan signifikan usia, IMT dan kadar PSA pada kedua kelompok, dan tidak ada perbedaan signifikan kadar GSTp1 dan MT1a antara kelompok. Kesimpulannya bahwa kadar PSA kelompok pekerja kantor lebih tinggi dibandingkan kelompok pekerja bengkel las, dimungkinkan karena rerata usia yang lebih tua.

Co-Authors Agung Saprasetya Dwi Laksana Agus Y Purnomo Aminuyati Dhadhang Wahyu Kurniawan Diah Krisnansari Diah Krisnansari Dzicky Rifqi Fuadi Fitranto Arjadi Fitranto Arjadi Hajid Rahmadianto Mardihusodo Hasnah Mutfii Joko Mulyanto Joko Mulyanto Lantip Rujito Lily Kusumawati Burkon M. Zaenuri Syamsu Hidayat Madya Ardi Wicaksono MM Rudi Prihatno, MM Rudi Muhammad Zaenuri Syamsu Hidayat Nendyah Roestijawati Nur Signa Aini Gumilas Octavia Permata Sari Rahayujati TB Siti Munfiah Thianti Sylviningrum Tirta Wardana Tri Lestari Wahyu Siswandari Wahyudin Wahyudin Wisnuwijoyo AP

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