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All Journal ACTA VETERINARIA INDONESIANA Jurnal Veteriner Jurnal Ilmiah Ilmu-Ilmu Peternakan The International Journal of Tropical Veterinary and Biomedical Research Jurnal Medika Veterinaria

Henni Vanda

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Author-ID : 409439

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Articles

Aktivitas Hepatoprotektif Ekstrak Etanol Daun Kucing-kucingan Acalypha indica L.) pada Tikus Putih (Rattus Novergicus) yang Diinduksi Parasetamol T Armansyah TR; Amalia Sutriana; Dwinna Aliza; Henni Vanda; erdiansyah rahmi
Jurnal Ilmiah Ilmu-Ilmu Peternakan Vol. 13 No. 6 (2010): Mei 2010
Publisher : Fakultas Peternakan Universitas Jambi

The research has been conducted to determine hepatoprotective effect of ethanolic extract of Acalypha indica L. leaves on rats (Rattus novergicus) induced with paracetamol. The study was performed following a completely randomized design, using 45 male rats (Rattus novergicus) divided into 5 groups. Rats in group 1 (K1) were given CMC 1 % for 7 days and followed by aquadest administration 8 hours post given CMC on day 7. Group 2 was given CMC 1 % for 7 days and treated with paracetamol at dose 2,5 g/kg BW 8 hours post given CMC on day 7. Groups 3 (K3), 4 (K4), and 5 (K5) were pretreated with ethanolic extract of Acalypha indica L. leaves at the dose of 50, 100, and 200 mg/kg BW for 7 days respectively, followed by paracetamol administration at the dose of 2.5 g/kg BW in the next 8 hours on day 7. Paracetamol hepatotoxicity and extracts activity were measured based on SGPT and SGOT activity level on day 0, 8 hours after last administration of extract on day 7, and 24 hours post paracetamol administration. Data were analyzed using one way ANOVA. The result showed that the administration of ethanolic extract of Acalypha indica leaves at the dose of 50, 100, and 200 mg/kg BW was significantly reduced SGPT and SGOT level (P<0,05) in rats that were induced with paracetamol. Based on the results of SGPT and SGOT serum activity, it can be concluded that ethanolic extract of Acalypha indica L. potential as hepatoprotective agent.

Combination of Areca catechu , Sauropus androgynous , and Mineral Block is Effective to control Nematode in Goats Henni Vanda; Muhammad Hambal; Farida Athailah; Mustafa Sabri
The International Journal of Tropical Veterinary and Biomedical Research Vol 2, No 2 (2017): Vol. 2 (2) November 2017
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

A study has been conducted to investigate the effect of two local herbs in Indonesia; Areca catechu nut and Sauropus androgynous leaf, combined with mineral block to treat gastro intestinal nematode in goats. A.catechu is well known to have anthelmintic property due to its alkaloid and tannin content, and S.androgynus also contains tannin, alkaloid and steroid that will enhance the anthelmintic property of those herbals. As many as 80 goats had been divided into 4 groups; 20 were treated with albendazole (Group A), 20 were given A.catechu and S.androgynus (Group B), 20 were given combination of A.catechu, S.androgynus, and mineral block (Group C), and 20 as negative control (Group D). The result revealed that herbal treatment showed significantly effective toward nematodes in gastro intestinal, demonstrated by declining egg worm of Group B and C. Body weight improvement and overall performance in Group C was higher compared to other groups. However, goats treated with albendazole showed slightly better results in the decreasing amount of egg worms found after treatment. Nevertheless, A.catechu and S.androgynus are potential anthelmintic herbal; combination with mineral block will enhance the anthelmintic activity. Therefore they are good options for treating helminthiasis in livestock.

Mammary Gland Tumor In Cat And Therapeutic Approach: A Case Report Muhammad Hambal; Rizka Ayuni; Henni Vanda; Mustafa Sabri
The International Journal of Tropical Veterinary and Biomedical Research Vol 3, No 1 (2018): Vol. 3 (1) May 2018
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

This report describes a case of mammary gland tumor in a 1-year-old female cat using a mastectomy approach. The tumor was located on dexter side of mammae. Blood analysis showed good condition of the patient and ready for surgery. Mastectomy was conducted to remove the mass, and the tumor size was measured 7x5x4 cm with solid appearance. The cat was given antibiotics to prevent infection, and the wound dried in five days.

8. Aedes Mosquitoes Abundance In Relation To Some Climatic Factors In Banda Aceh City, Indonesia Farida Athaillah; Muhammad Hambal; Yudha Fahrimal; Muttaqien Bakri; Ellyawardani Ellyawardani; Henni Vanda; Abu Hassan Ahmad
The International Journal of Tropical Veterinary and Biomedical Research Vol 1, No 1 (2016): Vol. 1 (1) May 2016
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Dengue viruses and their mosquito vectors as an endemic disease in Indonesia are sensitive to their environment. The rising incidence of dengue is influenced by many factors, climate is one of them. Temperature, rainfall and humidity have well-defined roles in the transmission cycle. Changes in these conditions may contribute to increasing incidence. The purpose of this research was to determine the correlation between the dengue vector abundance and some climatic factors (temperature, rainfall and humidity) in Banda Aceh city after the tsunami. We also examined the potential effects of climate variations on dengue epidemiological pattern in indoor and outdoor of tsunami affected areas in Banda Aceh City during January â€“ December 2010. Data processing was performed using SPSS and will be presented in tabular form. Pearson correlation test for parametric test and Spearman correlation coefficients for non-parametric test were performed to investigate the overall correlation between Aedes eggs abundance rates and some meteorological variables such as temperatures (0C), relative humidity (RH), and rainfall (RR). The result showed that the total egg populations in indoor and outdoor of tsunami affected areas are not significantly different among those factors. There was a positive correlation between eggs abundance and rainfall, but negatively correlated with temperature and relative humidity. From this result we can conclude that the abundance of Aedes eggs is not significantly correlated to temperature and humidity in indoor and outdoor of tsunami affected areas in Banda Aceh City.

Black Cumin Seed Extract Decrease Motility and Shortening Mortality Time of Ascaridia galli Worm In Vitro Henni Vanda; Ahmad Khairi Abadi; Muhammad Hambal; Farida Athaillah; Wahyu Eka Sari; Frengki Frengki; Daniel Daniel
Jurnal Veteriner Vol 24 No 1 (2023)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/jveteriner.2023.24.1.63

Ascaridiasis caused by roundworm Ascaridia galli is one of important diseases in poultry industry in Indonesia. This disease can affect economic losses in the form of death, growth retardation, reduced egg production as well as trigger for secondary viral or bacteria infections. Control of this nematode requires a good strategy to avoid the risk of anthelmintic resistance, one of which is the use of herbal medicine such as black cumin seed (Nigella sativa). This study was aimed to determine the level of motility and mortality time of A. galli after treated with black cumin seed extract in vitro. In this study, black cumin seed was extracted using ethanol 96%, and then diluted to 15% (P1), 25% (P2), and 45% (P3) concentration. Pyrantel pamoate preparation was used as positive control (C1), and carboxymethyl cellulose (CMC) solution as negative control (C0). Observations were carried out every 15 minutes until all the treatment worms died. The results revealed that the motility and mortality time of A. galli were significantly different in some treatment groups. The mortality time of group C0, C1 , P1, P2, and P3 were 2592, 801, 1557, 1350, and 612 minutes, respectively. 45% of black cumin seed extract had the ability to decrease worm motility, and it showed the shortest mortality time compared to other treatment groups. It can be concluded that ethanolic extract of black cumin seeds had potential anthelmintics property on A. galli worms

Nigella Sativa Seed Extract has Potential Antimicrobial Activity on Pasteurella multocida in Vitro Vanda, Henni; Zakya Ardi; Sari, Wahyu Eka; Hambal, Muhammad
Acta VETERINARIA Indonesiana Vol. 11 No. 3 (2023): November 2023
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.11.3.228-233

Nigella sativa known as black cumin has various bioactive compounds to treat many diseases. Some of the benefits of N. sativa seed are as immune booster, antihistamin, anti-diabetic, antihypertension, antiinflammatory, antimicrobial, and antitumor. This study aimed at determining the antimicrobial activity and finding out the effective concentration of N. sativa seed ethanolic extract on Pasteurella multocida in vitro. N. sativa seed extract was divided into three groups consisting of 15% extract (T1), 25% extract (T2), 45% extract (T3), and chloramphenicol was used as positive control. For antimicrobial test, Kirby Bauer diffusion method was used, and the data were analyzed by ANOVA. The results revealed that T3 had the most effective antimicrobial activity, shown by the largest inhibition zone (17.72 mm), followed by T2 (15.93 mm) and T1 (10.75 mm). ANOVA test results showed significant differences (P<0.05) in each group. The antimicrobial effect of T3 and T2 was categorized as strong, whilst T1 as moderate. From the results it can be concluded that N. sativa seed extract had strong and moderate inhibition activity on the growth of P. multocida, therefore, N. sativa seed is a potential candidate for antimicrobial drug development againts P. multocida.

Effectiveness of Kersen Leaf Extract Cream (Muntingia calabura L.) on The 3rd Day of Incision Healing Process on The Skin of Streptozotocin Induced White Rats (Rattus norvegicus) Salim, M. Nur; Azhar, Nurul Sakinah; Masyitha, Dian; Vanda, Henni; Rosmaidar, Rosmaidar; Zainuddin, Zainuddin
Jurnal Medika Veterinaria Vol 18, No 2 (2024): J. Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v18i2.40208

A wound is a break in the continuity of tissue, which physiologically undergoes several phases of healing: hemostasis, inflammation, proliferation, and maturation. The wound healing phase can be prolonged if one experiences metabolic disorders such as diabetes mellitus (DM). Treatment is necessary to prevent the prolongation of the wound healing phase in DM patients, one of which involves using traditional medicine, specifically cherry plants. This study aimed to determine the effectiveness of cherry leaf extract cream in the healing process of incision wounds on day 3 on the skin of white rats induced by streptozotocin. The samples used were 12 white rats, aged approximately 3 months, with a body weight of 179.25 12.64 g. The rats were injected intraperitoneally with streptozotocin at a dose of 45 mg/kg BW. After 72 hours, an incision was made in the paravertebral section with a length of 2 cm and a depth reaching the subcutaneous layer. Therapy was administered for 3 days in several groups. Group KI served as the negative control (cream base), KII as the positive control (metformin 4.5 mg/kg BW and silver sulfadiazine 0.1% cream), KIII (2 ml cherry leaf extract and topical therapy with 5% cherry leaf extract cream), and KIV (2 ml cherry leaf extract and 15% cherry leaf extract cream). The results of the average number of inflammatory cells in KI, KII, KIII, and KIV were 117.403.17; 87.878.97; 104.405.97; and 91.405.39, respectively, with P0.05. The average number of new blood vessels in KI, KII, KIII, and KIV were 1.070.64; 4.870.64; 5.800.80; and 6.001.31, respectively, with P0.05. The conclusion of this study is that the administration of cherry leaf extract and 15% cherry leaf extract cream can reduce inflammatory cell infiltration and accelerate the growth of new blood vessels

In Vitro Analysis of Antibacterial Activity of Black Seed Oil Against Salmonella Typhi Zulfayanto, Indri; Vanda, Henni; Hambal, Muhammad; Sari, Wahyu Eka; Muttaqien, Muttaqien
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.48983

Salmonella sp. is one of the bacteria that causes diarrhea in animals and humans, especially in naive animals whose immune systems have not yet been formed. In relation to the emergence of antibiotic resistance against Salmonella typhi, it is necessary to develop an innovation regarding alternative medicines that use herbal medicines as antibacterials, one of which is black seed oil which contains active substances such as thymoquinone. Nigella sativa, commonly known as black seed, has long been used as herbal medicine with many benefits. This study aimed to determine the antibacterial activity of black seed oil against S. typhi bacteria in vitro. This study used S. typhi ATCC 14028, which had been previously re-identified using Gram staining. The black seed oil for the antibacterial test was prepared with three concentrations, 45%, 70%, and 100%, with dimethyl sulfoxide (DMSO) as a negative control and ciprofloxacin as a positive control. Black seed oil's antibacterial test was carried out using the Kirby Bauer method. The data was analysed descriptively. The results showed that black seed oil was not effective in inhibiting the growth of S. typhi, where the inhibition zone formed was less than 5 mm. This is because the antigenic structure of S. typhi has Vi antigens or capsular antigens which are made of polysaccharide polymers found outside the cell to protect the bacteria from outside influences. Therefore, the active ingredients in the black seed oil was unable to reach the site of action on the bacteria so they failed to inhibit or kill the S. typhi bacteria. It can be concluded that the black seed oil used in this study was not effective in inhibiting the growth of S. typhi ATCC 14028

Co-Authors Abu Hassan Ahmad Ahmad Khairi Abadi Amalia Sutriana Azhar, Nurul Sakinah Daniel Daniel Dian Masyitha Dwinna Aliza Ellyawardani Ellyawardani Erdiansyah Rahmi Erdiansyah Rahmi Farida Athailah Farida Athaillah Farida Athaillah FRENGKI FRENGKI M. Nur Salim Muhammad Hambal Muhammad Hambal Muhammad Hambal Mustafa Sabri Muttaqien Bakri Muttaqien Muttaqien, Muttaqien Rizka Ayuni Rosmaidar Rosmaidar, Rosmaidar Sari, Wahyu Eka T Armansyah TR Yudha Fahrimal Zainuddin, Zainuddin Zakya Ardi Zulfayanto, Indri

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