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All Journal BALI MEDICAL JOURNAL (BMJ) Dental Journal (Majalah Kedokteran Gigi) Indian Journal of Forensic Medicine & Toxicology

RM Coen Pramono D

Department Of Oral And Maxillofacial Surgery Faculty Of Dental Medicine, Universitas Airlangga

Author-ID : 3196722

Dentistry Medicine & Pharmacology Public Health

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Placement of fin type dental implant in three different surgical situations of alveolar bone Coen Pramono D
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 1 (2007): March 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Three different dental implant placements according to surgical implant bed situations were observed in its bone integration 3 months after dental implant insertion. This observation was done on implant system which has plateau or fin system. Elf implants were placed in the upper jaw in two patients. In case one, two implants were inserted immediately after tooth extraction, and the other six implants were placed in the alveolar crest regions in delayed implantation or in which the teeth had been extracted over 6 months of period. In case two, three implants were inserted in the post trauma region in the anterior maxilla, which the labial plate had been lost and reconstructed with bone grafting procedure using a mixture of alloplastic and autogenous bones. The alveolar reconstruction was needed to be performed due to only thin alveolar crest width was left intact. All of those implants observed showed in good integration.

Mandible vertical height correction using lingual bone-split pedicle onlay graft technique Coen Pramono D
Dental Journal (Majalah Kedokteran Gigi) Vol. 39 No. 3 (2006): September 2006
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

As edentulous mandible become atrophic, a denture bearing area will also be reduced. Difficulty in the removable prosthesis rehabilitation will be present as well. The purpose of this paper reports an innovative surgical technique to cope a problem of unstable complete lower denture due to bone atrophy and resulted of vertical height reduction of the anterior region of the mandible necessary for denture retention. Vertical advancement of the lower jaw using lingual bone split pedicle onlay graft technique in the anterior region of the mandible and followed by secondary epithelization vestibuloplasty in achieving the vertical height dimension. The surgery was achieved satisfactorily as the vertical dimension of the mandible anterior region had increased and the denture seated more stable comparing with the previous denture worn by the patient. It concluded that the surgery was achieved with a great result as the vertical height of the anterior region of the mandible had increased positively therefore lead the denture seated more stable.

Placement of replace select Ti-Unite-coated type implants using a combination of immediate and submerge techniques after tooth extraction Coen Pramono D
Dental Journal (Majalah Kedokteran Gigi) Vol. 39 No. 2 (2006): June 2006
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

The high success rate of immediate implant placement both in the anterior and posterior regions were reported by many authors, therefore applying this techniques can be considered as a safe surgical procedure and minimizing the dental office visit for patient satisfaction. This paper reports the outcome of immediate placement of implants following extraction of anterior maxillary teeth. Combination technique of immediate and submerge implant placements including bone grafting procedure were used. Four implants with TiUnite surface type were placed immediately in two patients with the short-term result indicated that this technique may serve as a simple and safe procedure for immediate implant placement. It was concluded that immediate implant placement technique combined with TiUnite implant surface was successful in treating region directly after tooth extraction therefore this technique can be use as an alternative surgical method for dental implant rehabilitation.

Lip and allar base dimensions among adolescence in healthy and post unilateral cleft lips correction in deutro-malaid population Coen Pramono D
Dental Journal (Majalah Kedokteran Gigi) Vol. 39 No. 1 (2006): March 2006
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

The purpose of this study is to observe the differences between some anthropometric values of the lip and allar base area in normal and those who had undergone incomplete unilateral cleft lip surgical correction using Millard’s I technique. The investigation was done on male und female adolescence of 12–15 years of age. Thirteen anthropometric dimension variables were observed, as X1 = width of the allar base, X2 = the distance between two corners of the mouth, X3 = the distance between the center of the lip and the right mouth corner, X4 = the distance between the center of the lip and the left mouth corner, X5 = the distance between the center of the allar base and the center of the of upper lip, X6 = the distance between upper part of two philtrum pillars, X7 = the distance between two philtrum pillars base, X8 = the height of right philtrum pillar, X9 = the height of left philtrum pillar, X10 = the distance between the right allar base to the right mouth corner, X11 = the distance between the left allar base to the left mouth corner, X12 = the width of the right nostril, and X13 = the width of the left nostril. The t-test analysis showed the average of the anthropometric lip and allar base dimensions among male adolescence groups in variables of X1, X2, X4, X5, X6, X7, X10, X11, X12, and X13 shown with significant differences from those of some variables which had undergone incomplete unilateral cleft lip surgical correction (p < 0.05), and no significant differences shown in the variables of X3, X6, X8, and X9 (p > 0.05). The result of the test among the female group presented a significant difference in variables of X4, X5, X6, X9, X11, X12 and X13 (p < 0.05), differed what given in variables of X1, X2, X3, X7 and X8 showed with no significant difference (p > 0.05). It concluded that there are differences in dimensions of the lips and allar bases among normal and post-surgical groups both in adolescence males and females.

Problem in the surgical correction of long-face with vertical open bite Coen Pramono D
Dental Journal (Majalah Kedokteran Gigi) Vol. 38 No. 4 (2005): December 2005
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Long-face cases usually need both treatment of orthodontic and surgery. The problem appearing in the correction of long-face might be able to be related with some difficult factors such as the crowded teeth and excessive vertical height. A class III malocclusion and excessive open bite can be also followed in long face. This situation might worsen the facial aesthetic condition and increase the difficulty in orthodontic treatment. The orthodontic approach is oriented toward positioning the teeth pre-surgically to facilitate the surgical plan. The form of mandible which has grown in the downward direction in the area of mandible angle makes an extreme vertical open bite. The maxilla is usually presented with a maxillary hypolasia. Double-jaw surgery was done as the correction of the lower jaw alone would produce a flattened face appearance and difficulty in repositioning the mandible to achieve a good facial performance. Several cephalometric points were measured to observe the facial situation progress after surgery. Two cases of longface are reported, and the same surgical treatments were performed and showed different results.

The advantage of the three dimensional computed tomographic (3 D-CT) for ensuring accurate bone incision in sagittal split ramus osteotomy Coen Pramono D
Dental Journal (Majalah Kedokteran Gigi) Vol. 38 No. 1 (2005): March 2005
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Functional and aesthetic dysgnathia surgery requires accurate pre-surgical planning, including the surgical technique to be used related with the difference of anatomical structures amongst individuals. Programs that simulate the surgery become increasingly important. This can be mediated by using a surgical model, conventional x-rays as panoramic, cephalometric projections and another sophisticated method such as a three dimensional computed tomography (3 D-CT). A patient who had undergone double jaw surgeries with difficult anatomical landmarks was presented. In this case the mandible foramens were seen highly relatively related to the sigmoid notches. Therefore, ensuring the bone incisions in sagittal split was presumed to be difficult. A 3D-CT was made and considered to be very helpful in supporting the pre-operative diagnostic.

The role of ubiquinone supplementation on osteogenesis of nonvascularized autogenous bone graft Irham Taufiqurrahman; Achmad Harijadi; Roberto M. Simanjuntak; Coen Pramono D; Istiati Istiati
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 2 (2015): June 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Ubiquinone is one of food supplement which is known have positive effect in wound healing. However the study to evaluate the possible role of ubiquinone in bone healing in autogenous bone grafting after mandibular resection has not been studied. An in vitro study is required to evaluate whether ubiquinone or coenzyme Q-10 (CoQ10) has a positive effect on osteogenesis. Viability test of CoQ10 and a model of osteogenic-induced and hypoxic-condition mesenchymal stem cell culture were established to support the study. Purpose: The study was made to evaluate the role of ubiquinone in osteogenesis by analyzing the toxicity effect and the optimal dose of CoQ10 that might interfere in bone marrow derived mesenchymal stem cell (BM-MSC) that was dose in cell culture medium. The BM-MSC culture under hypoxia condition were also observed. Method: The toxicity and the optimum viability concentration of ubiquinone were observed using MTT assay. The osteogenic differentiation under hypoxic condition was done on BM-MSC in osteogenic medium that composed of ascorbic acid, glycerolphosphate and dexamethasone in hypoxia chamber for 21 days. Osteogenic differentiation and cellular hypoxia features were tested with immunocytochemical staining using anti-Runx2 and anti-HIF1α monoclonal antibody, respectively. Result: The maximum density value of 1.826 was found in the group of ubiquinone concentration of 75μM/ml, increasing of in concentration of ubiquinone resulted with the decrease ofoptical density of CoQ10. Statistic analysis using Anova showed with no significant difference among groups with various concentration. Immunocytochemical staining showed that Runx2 expression in 3% hypoxia group (p<0.05). Conclusion:Ubiquinone was found non toxic in its optimum dose of 75μM/ml, showed by optimum result in the expression ofRunx2 and HIF1α further study is necessary to evaluate the angiogenic and osteogenic effect ofubiquione.

A study of cytotoxicity and proliferation of Cosmos caudatus Kunth leaf extract in human gingival fibroblast culture Zhafira Nur Shabrina; Ni Putu Mira Sumarta; Coen Pramono
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 4 (2018): December 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Post-extraction dental sockets clinically resolve within a period of 3-4 weeks. However, complete healing and bundling of gingival fibers may require several months. Medication is therefore required to accelerate the healing process. Cosmos caudatus (C. caudatus), a local plant with antioxidant properties and high calcium content, has the potential to promote wound healing while also reportedly capable of strengthening bone. Previous studies have demonstrated the effectiveness of C. caudatus as an alternative treatment for post-menopausal osteoporosis by investigating the dynamic and cellular parameters of bone histomorphometry. Purpose: The study aimed to examine the citotoxicity and proliferation of human gingival fibroblast cells culture after the application of C. caudatus extract. Methods: Cultures of human gingival fibroblast cells with 5x104 cell density were divided into two groups and placed in a 30-well culture dish. The control group contained human gingival fibroblast cell culture without extract, while the experimental group consisted of human gingival fibroblast cells culture with extract. The concentrations of extract were 1200 μg/ml, 600 μg/ml, 300 μg/ml, 150 μg/ml, and 75 μg/ml. A toxicity test was conducted and the optimum concentration evaluated using an MTT assay, while fibroblast numbers on were calculated days 1 and 2 by means of a hemocytometer. Research data was analyzed using a one-way ANOVA test. Results: No toxicity was found. The optimum concentration was 600 μg/ml and fibroblast proliferation was significantly higher in the experimental group compared to the control group, p=0.002 (P<0.05). Conclusion: C. caudatus leaf extract is non-toxic and increases the proliferation of human gingival fibroblast culture at an optimum concentration of 600 μg/ml.

The role of family history as a risk factor for non-syndromic cleft lip and/or palate with multifactorial inheritance Agung Sosiawan; Mala Kurniati; Coen Pramono Danudiningrat; Dian Agustin Wahjuningrum; Indra Mulyawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 54 No. 2 (2021): June 2021
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v54.i2.p108-112

Background: Cleft lip with or without cleft palate (CL/P) is a facial growth ‘disorder that occurs during gestation and has multifactorial causes owing to both genetic and environmental factors. Several factors can increase the likelihood of CL/P, and one of them is family history. Differences in results obtained from studies conducted across several countries concerning family history as a risk factor for CL/P suggest there is no consensus on how the condition is inherited. Purpose: This study aims to review the literature on the role of family history as a risk factor contributing to the incidence of non-syndromic CL/P (NSCL/P). Review: This review discusses the etiology of CL/P and the risk factors influencing the incidence of CL/P. The review also examines the criteria for inheriting multifactorial disorders to calculate the risks involved should there be a recurrence of the condition based on family history. Conclusion: CL/P is a type of multifactorial disorder with unclear etiology. Therefore, it is important to investigate the risk factors stemming from family history (which play an important role) related to the recurrence risk. Additionally, there should be focus on increasing genetic education and offering counselling to parents and pregnant women.

Degradation rate and weight loss analysis for freeze-dried, decellularized, and deproteinized bovine bone scaffolds Vidarta, Ramadhan Pramudya; Kamadjaja, David Buntoro; Danudiningrat, Coen Pramono; Amir, Muhammad Subhan; Rizqiawan, Andra; Yuliati , Anita; Darwis, Darmawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 1 (2025): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i1.p23-29

Background: Mandibular defects, often caused by trauma, tumors, infections, and congenital issues, are commonly treated with bone grafts. Tissue engineering plays a crucial role in bone reconstruction, with scaffolds such as deproteinized bovine bone matrix (DBBM), freeze-dried bovine bone (FDBB), and decellularized FDBB (Dc-FDBB) being studied for their efficacy. Decellularization reduces the antigenic potential of FDBB. These scaffolds are designed to degrade within the body. Purpose: To analyze the weight loss and degradation rates of FDBB and Dc-FDBB materials, using DBBM as a control. Methods: This in vitro experimental study, conducted over 2 months, employed a cross-sectional approach to analyze the weight loss and degradation rates of FDBB, Dc-FDBB, and DBBM scaffolds in a simulated body fluid (SBF) solution. Results: Under dynamic immersion conditions, DBBM exhibited the highest daily weight loss at 0.741% and a degradation rate of 0.466 mg/cm²/day, followed by Dc-FDBB at 0.568% and 0.418 mg/cm²/day and FDBB at 0.525% and 0.385 mg/cm²/day. Under static immersion conditions, DBBM also showed the highest weight loss at 0.255%, with a degradation rate of 0.165 mg/cm²/day, followed by Dc-FDBB at 0.245% and 0.163 mg/cm²/day, and FDBB at 0.168% with a degradation rate of 0.126 mg/cm²/day. Significant differences were observed between scaffold groups (p = 0.000). Conclusion: DBBM, Dc-FDBB, and FDBB scaffolds meet the optimal requirements for tissue engineering materials based on their weight loss and degradation rates. DBBM demonstrated the highest values among the scaffolds analyzed.

Co-Authors Achmad Harijadi Agung Sosiawan Amir, Muhammad Subhan Andra Rizqiawan Anita Yuliati Darmawan Darwis David B. Kamadjaja David Sontani Perdanakusuma Deya Karsari, Deya Dian Agustin Wahjuningrum Djodi Asmara Eryk Hendrianto Ester Arijani Rachmat Fedik A. Rantam, Fedik A. Hari Basuki Notobroto Helen Susilowati, Helen Istiati Istiati Kurniati, Mala Mala Kurniati Ni Putu Mira Sumarta Ni Wayan Tirtaningsih Pratiwi Soesilawati Roberto M. Simanjuntak Rosa Sharon Suhono Sularsih Sularsih Vidarta, Ramadhan Pramudya Yuliati , Anita Zhafira Nur Shabrina

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