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Aktivitas Antibakteri Ekstrak Etanol Biji Keluak (Pangium Edule) Terhadap Bakteri Salmonella Typhi Ricko Arie Jatmiko; Alvi Milliana; Christyaji Indradmojo
Journal of Islamic Medicine Vol 7, No 1 (2023): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2023
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v7i1.10546

Background: Typhoid fever often occurs in various countries in the world and generally occurs in countries with low levels of cleanliness. Typhoid fever is a systemic disease caused by Salmonella typhi bacterial infection. The main therapy for typhoid fever is antibiotics. The challenge of using synthetic antibiotics nowadays is the emergence of side effects of resistance. One of the plants that can be used as an antibacterial is extract of keluak seed (Pangium edule). This study aims to determine the antibacterial activity of keluak seed (Pangium edule) antibacterial extract on the growth of Salmonella typhi. This research is a quantitative type of experimental research with true experimental post-test control design). Method: The method used in this study used a qualitative phytochemical test and dilution of the tube. This study uses 6 concentrations which are 5, 10, 15, 20, 25, and 30 mg/ml. Bacterial suspension was used as negative control and extract 100 mg/ml was used as positive control. Result: Based on the phytochemical test show that the seeds of the keluak seed (Pangium edule) contain alkaloids and terpenoids. The extract of keluak seed seed has a MIC at a concentration of 10 mg/ml and MKC 30 mg/ml. MKC data were analyzed by the KruskalWallis test (significance p = 0,000) with (coefficient correlation= -0,990) the relationship between the two variables is very strong. Conclusion: The extract keluak seed (Pangium edule) seeds can inhibit the growth of S. typhi bacteria.

Pregnancy Complication Due to Malaria in Mice BALB/C : The Role of TNF-α, Anemia, and Low Birth Weight Alvi Milliana; Nurfianti Indriana; Zainabur Rahmah
Journal of Islamic Medicine Vol 7, No 1 (2023): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2023
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v7i1.20828

Background : Malaria infection in pregnant women or called placental malaria is characterized by the accumulation of Plasmodium-infected red blood cells in the intervillous space of the placenta. This causes adverse perinatal outcomes such as stillbirth, low birth weight, premature birth, and small neonates of gestational age while in the mother it causes anemia. Inflammatory responses such as TNF-α expression can promote complications in pregnancy. TNF-α plays an important role in the immune response in acute malaria but inhibits erythropoiesis. Objective : This study aims to determine the relationship between malaria infection and TNF-α expression with the incidence of anemia and birth weight in pregnant mice infected with Plasmodium berghei. Methods: Twenty BALB/C pregnant mice were divided into 2 groups, control group (10 pregnant mice without infection) treatment group (10 pregnant mice infected with Plasmodium berghei). TNF-α expression was observed by immunohistochemical method using anti-TNF-α Chip Grade antibody from abcam, anemia examination using Cyanmethemoglobin and all fetuses were weighed using an analytical balance. Statistical analysis using Structural Equation Modeling. Results: Malaria infection causes high expression of TNF-α in the placenta (tcount=2.97≥ ttable = 1.96), causes anemia (tcount=1,97≥ttable = 1.96) and causes low fetal weight tcount=2,16 ≥ ttable =1, 96. Conclusion: Malaria infection can cause high expression of TNF-α in the placenta causing anemia and low birth weight of the fetus

Innovation in the Utilization of Lemon for Phytonutrient Products as an Effort to Increase Income Generation for the Bocek Village Community Rahmi Annisa; Usman Pagalay; Alvi Milliana; Wirda Anggraini; Fitriyani Fitriyani; M Abbas Arriziq; Roihatul Mutiah
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 6, No 3 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v6i3.10095

Bocek Village is one of the villages in Karangploso District, Malang Regency, East Java Province, which has lemon production reaching 30 tons per month but is not supported by good sales management. Lemon (Citrus lemon) is one of the species of the genus citrus, and it has many benefits, such as anti-inflammatory, antimicrobial, anticancer, and antiparasitic activities. This community service aims to create innovative lemon-based products for phytonutrients to increase income generation for Bocek village, Karangploso district, Malang regency. The method used is ABCD (Asset Based Community Development). The activity was carried out on August 19 2023, in Bocek village, Karangploso district, Malang regency, with the participation of 30 housewives. The results of the activity were successful socialization and demonstrations of lemon slice and lemon squash products that were successfully made, and there were levels of public understanding with good (60%), sufficient (23%), and poor (17%) percentages. So, it can be concluded that training activities on using lemons for phytonutrient products can increase public knowledge and generate income in the future.

Pregnancy Complication Due to Malaria in Mice BALB/C : The Role of TNF-α, Anemia, and Low Birth Weight Milliana, Alvi; Indriana, Nurfianti; Rahmah, Zainabur
Journal of Islamic Medicine Vol 7, No 1 (2023): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2023
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v7i1.20828

Background : Malaria infection in pregnant women or called placental malaria is characterized by the accumulation of Plasmodium-infected red blood cells in the intervillous space of the placenta. This causes adverse perinatal outcomes such as stillbirth, low birth weight, premature birth, and small neonates of gestational age while in the mother it causes anemia. Inflammatory responses such as TNF-α expression can promote complications in pregnancy. TNF-α plays an important role in the immune response in acute malaria but inhibits erythropoiesis. Objective : This study aims to determine the relationship between malaria infection and TNF-α expression with the incidence of anemia and birth weight in pregnant mice infected with Plasmodium berghei. Methods: Twenty BALB/C pregnant mice were divided into 2 groups, control group (10 pregnant mice without infection) treatment group (10 pregnant mice infected with Plasmodium berghei). TNF-α expression was observed by immunohistochemical method using anti-TNF-α Chip Grade antibody from abcam, anemia examination using Cyanmethemoglobin and all fetuses were weighed using an analytical balance. Statistical analysis using Structural Equation Modeling. Results: Malaria infection causes high expression of TNF-α in the placenta (tcount=2.97≥ ttable = 1.96), causes anemia (tcount=1,97≥ttable = 1.96) and causes low fetal weight tcount=2,16 ≥ ttable =1, 96. Conclusion: Malaria infection can cause high expression of TNF-α in the placenta causing anemia and low birth weight of the fetus

Association Between Stress Level, Sleep Quality, Physical Activity With Cardiorespiratory Fitness In Medical Students: A Cross Sectional Study Rachmawati, Ermin; Milliana, Alvi; Filzah, Sefira Maulida; Kresnanda, Adhitya Wishnu
Journal of Islamic Medicine Vol 7, No 1 (2023): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2023
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v7i1.20429

Introduction Modern life style and high burden of academic tasks contribute to the upsurge of stress, poor sleep quality, lack of sufficient physical activity in medical student society nowadays. The unhealthy life style act as one cardiovascular risk factor which can be predicted using Cardiorespiratory Fitness (CRF) examination. Objectives to identify the association between stress, sleep quality, physical activity with CRF level among medical students. Design The cross-sectional data was collected between September until November 2021. A total of 38 male and 73 female students of Faculty of Medicine and Health Sciences UIN Maulana Malik Ibrahim Malang were participated in this study. Stress level was assessed with DASS-21, sleep quality with PSQI, physical activity with GPAQ questionnaire. The level of CRF was measured using the Harvard Step Test. Statistical analysis for bivariate correlation ordinal scale was tested using Spearman Rank. Results 83 participants (74,8%) had low CRF. Meanwhile, 76 participants (68,5%) experienced no stress. In addition, 75 participants (67,6%) had poor sleep quality. A total number of 79 participants (71%) had low physical activity. There was no significant correlation between stress level, sleep quality, physical activity with CRF ( p=0,962; 0,772; 0,114, respectively). The participants who had low physical activity and low CRF was found in 56 participants (50,45%). Conclusions There was no association between stress level, sleep quality, physical activity with CRF among medical students. Keywords: Cardiorespiratory fitness; Stress; Sleep quality; Physical activity.

Aktivitas Antibakteri Ekstrak Etanol Biji Keluak (Pangium Edule) Terhadap Bakteri Salmonella Typhi Jatmiko, Ricko Arie; Milliana, Alvi; Indradmojo, Christyaji
Journal of Islamic Medicine Vol 7, No 1 (2023): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2023
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v7i1.10546

Background: Typhoid fever often occurs in various countries in the world and generally occurs in countries with low levels of cleanliness. Typhoid fever is a systemic disease caused by Salmonella typhi bacterial infection. The main therapy for typhoid fever is antibiotics. The challenge of using synthetic antibiotics nowadays is the emergence of side effects of resistance. One of the plants that can be used as an antibacterial is extract of keluak seed (Pangium edule). This study aims to determine the antibacterial activity of keluak seed (Pangium edule) antibacterial extract on the growth of Salmonella typhi. This research is a quantitative type of experimental research with true experimental post-test control design). Method: The method used in this study used a qualitative phytochemical test and dilution of the tube. This study uses 6 concentrations which are 5, 10, 15, 20, 25, and 30 mg/ml. Bacterial suspension was used as negative control and extract 100 mg/ml was used as positive control. Result: Based on the phytochemical test show that the seeds of the keluak seed (Pangium edule) contain alkaloids and terpenoids. The extract of keluak seed seed has a MIC at a concentration of 10 mg/ml and MKC 30 mg/ml. MKC data were analyzed by the KruskalWallis test (significance p = 0,000) with (coefficient correlation= -0,990) the relationship between the two variables is very strong. Conclusion: The extract keluak seed (Pangium edule) seeds can inhibit the growth of S. typhi bacteria.

Evaluation of Health Screening for Hajj Pilgrims at Hajj Dormitory in Preventing the Spread of Infectious Diseases Widowati, Ade Triana; Astari, Lina Fitria; Milliana, Alvi
PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS Vol. 4 No. 2 (2025): APRIL
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/comorbid.v4i2.1716

Coronavirus disease 2019 (COVID-19) is a pneumonia caused by a new type of coronavirus, named Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The risk of spreading infectious diseases during Hajj is very high, given the mass migration of pilgrims from different countries. In the process of receiving pilgrims at the Sukolilo Hajj Dormitory in Surabaya, efforts to screen for COVID-19 and other infectious diseases are carried out by monitoring temperature using a thermal scanner. This study aims to evaluate the effectiveness of health screening of pilgrims at the Sukolilo Surabaya Hajj Dormitory in preventing the spread of infectious diseases, especially COVID-19. In addition, this study identifies factors that influence pilgrims' compliance with screening procedures as well as policy implications in improving health surveillance in the future. This study used a descriptive method with an observational approach to assess the health screening process of pilgrims arriving at the Sukolilo Hajj Dormitory in Surabaya in 2024. The research sample was selected using purposive sampling technique, involving pilgrims who had a body temperature ≥37.5°C or experienced respiratory symptoms. The results showed that most pilgrims who underwent body temperature screening and follow-up examinations complied with the established procedures. However, several factors were found to influence compliance, such as the level of understanding of the importance of screening, fear of the swab procedure, and post-travel fatigue factors. In this case, education provided by health workers is proven to increase pilgrims' compliance with the screening.

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