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Selective Termination for Fetal Anomaly in Twin Pregnancy Mirani, Putri
Indonesian Journal of Obstetrics and Gynecology Volume. 37, No. 1, January 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.41 KB)

Objective: To discussed the ethical aspects, the technique, optimal timing and the possible outcome of selective termination in anomalous twin pregnancy. Case description: A 28-year old primigravida, 21 weeks twin gestation, with giant hygroma coli in one fetus. The normal fetus was compressed by the anomalous fetus with oligohydramnios. The parent decided to undergo selective termination of the abnormal fetus. The procedure perform was intracardiac injection of potassium chloride (KCl). Eight milliliters of KCl were injected into fetal cardiac, followed by bradicardia and asystole of the anomalous twin. A week after the procedure, the normal fetus also died and delivered spontaneously after induction. Conclusion: Selective termination for fetal anomaly in twin pregnancy have some aspects to be considered. [Indones J Obstet Gynecol 2013; 37-1: 57-60] Keywords: selective feticide, selective termination

Effectiveness of Oral Misoprostol to Prevent Postcesarean Section Urinary Retention Mahadika, Febrinata; Fauzi, Amir; Mirani, Putri; Theodorus, Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: to determine the effect of misoprostol on the incidence of urinary retention in post cesarean section patients by measuring maternal residual urine volume 6 hours after catheter removal. Methods: This was a single-blind randomized controlled trial, at Department of Obstetrics and Gynecology Mohammad Hoesin Palembang Hospital from October 2016 to February 2017. Samples were patients who underwent cesarean section, either elective or emergencies treated at Department of Obstetrics and Gynecology Hospital, Mohammad Hoesin Palembang. Subjects were allocated into two groups: treatment group (receiving misoprostol) and placebo group. Urinary retention is diagnosed if post-voiding residual urine volume after Foley catheter removal was > 200 ml. Statistical analysis was performed using SPSS 17.0 Results: There were no differences in mean time between of urination between control group (placebo) and 600μg oral misoprostol group. The average of urine volume, and residual urine volume between control group (placebo) and 600μg oral misoprostol group was significantly different. 600μg misoprostol orally can increase the amount of urine and reduce the volume of urinary residue after cesarean section. Conclusion: 600μg oral misoprostol can increase urine volume and reduce volume of residual urine post cesarean section Keywords: Misoprostol, urinary retention, cesarean section   Tujuan: untuk mengetahui pengaruh misoprostol terhadap kejadian retensi urin pada pasien operasi seksio sesaria dengan mengukur volume residu urin maternal 6 jam setelah kateter dilepaskan. Metode: Penelitian uji klinik acak berpembanding (Randomized Controlled Trial) secara single blind (tersamar tunggal) ini dilakukan di Departemen Obstetri dan Ginekologi RSUP Mohammad Hoesin Palembang mulai bulan Oktober 2016 sampai dengan Februari 2017. Sampel penelitian adalah semua pasien seksio sesaria, baik elektif maupun emergensi yang dirawat di Departemen Obstetri dan Ginekologi RSUP Mohammad Hoesin Palembang. Subjek dialokasikan menjadi 2 kelompok yaitu kelompok penanganan yang menerima misoprostol dan kelompok placebo. Retensio urin didiagnosis jika volume residu urin pasca berkemih setelah kateter Foley dilepaskan >200 ml. Analisis statistik dilakukan dengan menggunakan SPSS 17.0 Hasil:Tidak terdapat perbedaan rerata waktu urinasi antara kelompok kontrol (plasebo) dengan misoprostol peroral 600µg.Terdapat perbedaan rerata jumlah urine, dan volume residu urine antara kelompok kontrol (plasebo) dengan misoprostol peroral 600µg. Misoprostol per oral 600µg dapat meningkatkan jumlah urin dan mengurangi volume residu urin pasca persalian seksio sesaria. Kesimpulan:. Misoprostol per oral 600µg dapat meningkatkan jumlah urin dan mengurangi volume residu urin pasca persalian seksio sesaria Kata kunci: Misoprostol, retensio urin, seksio sesaria

Selective Termination for Fetal Anomaly in Twin Pregnancy Mirani, Putri
Indonesian Journal of Obstetrics and Gynecology Volume 37, No. 1, January 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To discussed the ethical aspects, the technique, optimal timing and the possible outcome of selective termination in anomalous twin pregnancy. Case description: A 28-year old primigravida, 21 weeks twin gestation, with giant hygroma coli in one fetus. The normal fetus was compressed by the anomalous fetus with oligohydramnios. The parent decided to undergo selective termination of the abnormal fetus. The procedure perform was intracardiac injection of potassium chloride (KCl). Eight milliliters of KCl were injected into fetal cardiac, followed by bradicardia and asystole of the anomalous twin. A week after the procedure, the normal fetus also died and delivered spontaneously after induction. Conclusion: Selective termination for fetal anomaly in twin pregnancy have some aspects to be considered. [Indones J Obstet Gynecol 2013; 37-1: 57-60] Keywords: selective feticide, selective termination

Effectiveness of Oral Misoprostol to Prevent Postcesarean Section Urinary Retention Mahadika, Febrinata; Fauzi, Amir; Mirani, Putri; Theodorus, Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: to determine the effect of misoprostol on the incidence of urinary retention in post cesarean section patients by measuring maternal residual urine volume 6 hours after catheter removal. Methods: This was a single-blind randomized controlled trial, at Department of Obstetrics and Gynecology Mohammad Hoesin Palembang Hospital from October 2016 to February 2017. Samples were patients who underwent cesarean section, either elective or emergencies treated at Department of Obstetrics and Gynecology Hospital, Mohammad Hoesin Palembang. Subjects were allocated into two groups: treatment group (receiving misoprostol) and placebo group. Urinary retention is diagnosed if post-voiding residual urine volume after Foley catheter removal was > 200 ml. Statistical analysis was performed using SPSS 17.0 Results: There were no differences in mean time between of urination between control group (placebo) and 600μg oral misoprostol group. The average of urine volume, and residual urine volume between control group (placebo) and 600μg oral misoprostol group was significantly different. 600μg misoprostol orally can increase the amount of urine and reduce the volume of urinary residue after cesarean section. Conclusion: 600μg oral misoprostol can increase urine volume and reduce volume of residual urine post cesarean section Keywords: Misoprostol, urinary retention, cesarean section   Tujuan: untuk mengetahui pengaruh misoprostol terhadap kejadian retensi urin pada pasien operasi seksio sesaria dengan mengukur volume residu urin maternal 6 jam setelah kateter dilepaskan. Metode: Penelitian uji klinik acak berpembanding (Randomized Controlled Trial) secara single blind (tersamar tunggal) ini dilakukan di Departemen Obstetri dan Ginekologi RSUP Mohammad Hoesin Palembang mulai bulan Oktober 2016 sampai dengan Februari 2017. Sampel penelitian adalah semua pasien seksio sesaria, baik elektif maupun emergensi yang dirawat di Departemen Obstetri dan Ginekologi RSUP Mohammad Hoesin Palembang. Subjek dialokasikan menjadi 2 kelompok yaitu kelompok penanganan yang menerima misoprostol dan kelompok placebo. Retensio urin didiagnosis jika volume residu urin pasca berkemih setelah kateter Foley dilepaskan >200 ml. Analisis statistik dilakukan dengan menggunakan SPSS 17.0 Hasil:Tidak terdapat perbedaan rerata waktu urinasi antara kelompok kontrol (plasebo) dengan misoprostol peroral 600µg.Terdapat perbedaan rerata jumlah urine, dan volume residu urine antara kelompok kontrol (plasebo) dengan misoprostol peroral 600µg. Misoprostol per oral 600µg dapat meningkatkan jumlah urin dan mengurangi volume residu urin pasca persalian seksio sesaria. Kesimpulan:. Misoprostol per oral 600µg dapat meningkatkan jumlah urin dan mengurangi volume residu urin pasca persalian seksio sesaria Kata kunci: Misoprostol, retensio urin, seksio sesaria

Pulmonary hypertension in pregnancy Bernolian, Nuswil; Kesty, Cindy; Mirani, Putri; Lestari, Peby Maulina; Martadiansyah, Abarham; Agustria, Rizky
Indonesian Journal of Perinatology Vol. 5 No. 1 (2024): Available online: 1 June 2024
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v5i1.36

Pulmonary hypertension (PH) is a persistent increase in mean pulmonary arterial pressure (mPAP) of at least 20–25 mm Hg during right cardiac catheterization. For every million patients, there were 97 PH cases. Women are more likely than men (1.7:1) to receive a diagnosis, with a mean age of 37 years. The classification, pathophysiology, mechanism, and management of postpartum hemorrhage (PH) are the main aims of this review study. Pulmonary artery hypertension (PAH), pulmonary hypertension (PH) associated with left heart disease, pulmonary hypoxia and/or lung illnesses, chronic thromboembolic PH, and PH with unknown multifactorial processes are the five categories into which PH is divided. Women, particularly those of reproductive age, make up about 80% of individuals with idiopathic PAH. Pregnancy-related PH is one of the long-standing heart conditions with a significant morbidity and mortality rate. Its estimated death rate ranges from 30.56%. Pregnancy is therefore not advised in PH patients. Treating people with PH requires early diagnosis and effective treatment. These patients have optimism because of the impending PH medications (phosphodiesterase type 5 inhibitors, nitric oxide, endothelin receptor antagonists, and calcium channel blockers) as well as the advancements in hemodynamic monitoring and intensive care in PH specialty facilities. Pregnant women with PH should be treated with a multidisciplinary approach, such as obstetricians, cardiologists, intensivists, and neonatologists.

The role of stem cells in obstetrics and gynecology: A systematic review Mirani, Putri; Legiran; Kesty, Cindy; Andrina, Hana
Majalah Obstetri & Ginekologi Vol. 31 No. 3 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I32023.129-138

HIGHLIGHTS Stem cell technology has various roles in the field of obstetrics and gynecology, including fertility study as well as tissue damage repair. Safety profile of stem cells technology use in human still need to be assessed. ABSTRACT Objective: This study aimed to review the role of stem cells in obstetrics and gynecology. Materials and Methods: This review used several databases, the PubMed, Wiley Online Library, and ScienceDirect to search open access original and review articles in English related to stem cells, obstetrics, and gynecology in the last 10 years. The results were analyzed qualitatively. Results: Out of 1,016 records identified through database searching, fifteen articles were eligible for review. Several articles reported the role of stem cells in endometrium repair. Stem cell can also increase endometrial thickness and increase the likelihood of pregnancy. In the field of gynecology, stem cells can be used as potential treatment for stress urinary incontinence and anal incontinence. Despite of all those abilities, stem cells might have errors, such as chromosomal abnormalities, epigenetic and genetic defect, which could potentially turn the stem cells into tumor initiating cells (TICs), thus can contribute to ectopic growth of endometrium (endometriosis), leiomyoma, leiomyosarcomas, and adeno-myosis. Conclusion: Stem cell technology has various roles in the field of obstetrics and gynecology, including fertility study as well as tissue damage repair. However, in-depth research to ensure the safety profile of stem cells technology use in human is necessary.

CXC Motif Chemokine Receptor 2: Glimpses into the Molecular Pathogenesis of Placenta Accreta Spectrum Disorder Mirani, Putri; Lestari, Peby Maulina; Murti, Krisna; Liberty, Iche Andriyani; Kesty, Cindy; Andrina, Hana; Stevanny, Bella
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.481

Investigation into the mechanism underlying excessive trophoblast invasion yields further strategies and insights for the diagnosis and treatment of placenta accreta spectrum disorder (PASD). We conducted a comprehensive literature review to analyze the relationship between CXCR2 expression and PASD, as well as the possibility of CXCR2 being used as a therapeutic and diagnostic biomarker for PASD. Chemokines are well-known mediators in the immune system, particularly for cell recruitment, angiogenesis, and tumor infiltration. CXCR2 is an important component of the immune system, particularly in neutrophils. One of the CXCR2 ligands, IL-8, has also been found to be expressed in the decidua and trophoblasts of humans and to promote autocrine or paracrine trophoblast migration and invasion. The potential role of CXCR2 in trophoblast invasion in PASD provides researchers with a glimpse into the molecular pathogenesis of PASD.CXC Motif Chemokine Receptor 2: Sekilas tentang Patogenesis Molekuler Gangguan Spektrum Plasenta AkretaAbstrakInvestigasi mekanisme invasi berlebihan trofoblas pada gangguan Spektrum Plasenta Akreta (SPA) akan memberikan lebih banyak strategi dan ide untuk diagnosis dan pengobatan. Kami melakukan tinjauan literatur yang komprehensif untuk menganalisis hubungan antara ekspresi CXCR2 dan SPA serta potensi CXCR2 sebagai penanda terapeutik dan diagnostik untuk SPA. Kemokin berperan sebagai mediator dalam sistem imun karena perannya dalam perekrutan sel, angiogenesis, dan infiltrasi tumor. CXCR2 mempengaruhi sistem imun, terutama pada neutrofil. Salah satu ligan CXCR2, IL-8, juga telah ditemukan diekspresikan dalam desidua dan trofoblas manusia serta untuk mempromosikan migrasi dan invasi trofoblas autokrin atau parakrin. Peran CXCR2 dalam invasi trofoblas pada SPA memungkinkan para peneliti untuk melihat sekilas patogenesis molekuler SPA.Kata kunci: penanda; CXCR2; plasenta akreta

Pencegahan Abortus pada Awal Kehamilan Bernolian, Nuswil; Pangemanan, Wim T.; Syamsuri, Ahmad Kurdi; Ansyori, M. Hatta; Mirani, Putri; Lestari, Peby Maulina; Martadiansyah, Abarham; Kesty, Cindy
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 3 November 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v6i3.403

Abortus merupakan suatu kejadian terminasi kehamilan dengan usia kehamilan <20 minggu dan berat janin <500 g. Angka kejadian abortus disebutkan sekitar 15% dari seluruh kehamilan. Terdapat beberapa faktor risiko abortus yaitu faktor risiko yang dapat dimodifikasi dan tidak dapat dimodifikasi. Beberapa faktor risiko yang dapat dimodifikasi yaitu faktor nutrisi, konsumsi kafein, alkohol, kebiasaan merokok, infeksi, paparan radiasi, beban kerja, dan pengaruh obat-obatan. Beberapa faktor risiko yang tidak dapat dimodifikasi, yaitu genetik, kelainan kongenital, dan lain-lain. Dengan mengetahui faktor risiko tersebut, dokter dapat melakukan pencegahan dan intervensi yang sesuai dengan kondisi masing-masing pasien yang mengalami abortus. Metode yang digunakan adalah tinjauan pustaka dengan menggunakan beberapa database seperti Pubmed, Wiley Online Library, dan ScienceDirect dari 10 tahun terakhir.Prevention of Miscarriage in Early PregnancyAbstractMiscarriage is an event of termination of pregnancy with < 20 weeks of gestation and fetal weight < 500 grams. The incidence of miscarriage is around 15% of all pregnancies. There are several risk factors for miscarriage, namely modifiable and non-modifiable risk factors. Some modifiable risk factors are nutritional factors, consumption of caffeine, alcohol, smoking habit, infection, radiation exposure, workload, and the influence of drugs. Several risk factors that can not be modified, namely genetics, congenital abnormalities, and others. By knowing these risk factors, doctors can carry out prevention and intervention according to the conditions of each patient who undergoes miscarriage. The method used is a literature review using several databases such as Pubmed, Wiley Online Library, and ScienceDirect from the last 10 years.Key words: miscarriage, prevention, risk factors, pregnancy.

Multigravida 37 Weeks Pregnant Not in Labour with Carotid Cavernous Fistula Life Single Fetus Head Presentation: Case Report Puspitasari, Dwi Cahya; Bernolian, Nuswil; Pangemanan, Wim Theodorus; Syamsuri, Ahmad Kurdi; Ansyori, Muhammad Hatta; Mirani, Putri; Lestari, Peby Maulina; Martadiansyah, Abarham
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.611

Background: Carotid cavernous fistula (CCF) is an abnormal shunt from the carotid artery to the cavernous sinus. The management of pregnant patients with CCF is individualized. The aims of this case report are to document a rare presentation of a multigravida at 37 weeks of gestation with a carotid cavernous fistula, describe clinical symptoms and management, report outcomes, and contribute insights to the medical literature.Case Report: The referred patient, G2P1A0, who was 37 weeks pregnant with a live single fetus in cephalic presentation, presented with left eye swelling persisting since the first pregnancy at 6 months gestation, associated with headaches. The patient underwent neurosurgical intervention at Mohammad Hoesin Hospital, including digital subtraction angiography (DSA). Currently, experiencing preterm labor symptoms, the management includes inpatient care, blood transfusion (Hb > 10 g/dL), and termination via the perabdominal approach.Discussion: A multigravida at 37 weeks pregnant in labor with carotid cavernous fistula and a live single fetus in head presentation, as existing literature suggests, has no clear link between maternal carotid cavernous fistula history and fetal outcomes. Despite concerns about potential fetal abnormalities and cancer risk from endovascular embolization therapy during pregnancy, postpartum follow-up with advanced digital subtraction angiography (DSA) is planned.Conclusion: The complexity of managing a multigravida at 37 weeks pregnant in labor with carotid cavernous fistula and a live single fetus in head presentation emphasizes the importance of a multidisciplinary approach for optimal maternal and fetal outcomes.Multigravida Hamil 37 Minggu Belum Inpartu dengan Fistula Cavernosa Karotis Janin Tunggal Hidup Presentasi Kepala: Laporan KasusAbstrakLatar belakang: Fistula kavernosus karotis (CCF) adalah celah/ lubang abnormal dari arteri karotis ke sinus kavernosus. Penatalaksanaan pasien hamil dengan CCF bersifat individual. Tujuan dari laporan kasus ini adalah untuk mendokumentasikan presentasi langka seorang multigravida pada usia kehamilan 37 minggu dengan fistula kavernosus karotis, mendeskripsikan gejala klinis dan penatalaksanaannya, melaporkan hasil, dan menyumbangkan wawasan untuk literatur medis.Laporan Kasus: Pasien yang dirujuk, G2P1A0, pada usia kehamilan 37 minggu dengan janin tunggal hidup dengan presentasi kepala, datang dengan pembengkakan mata kiri yang berlangsung sejak kehamilan pertama pada usia kehamilan 6 bulan, yang berhubungan dengan sakit kepala. Pasien menjalani intervensi bedah saraf di Rumah Sakit Mohammad Hoesin, termasuk Digital Subtraction Angiography (DSA). Saat ini, mengalami gejala persalinan prematur, penatalaksanaan yang dilakukan meliputi rawat inap, transfusi darah (Hb > 10 g/dL), dan terminasi melalui pendekatan perabdominal.Diskusi: Seorang multigravida dengan usia kehamilan 37 minggu yang melahirkan dengan fistula kavernosa karotis dan janin tunggal hidup dengan presentasi kepala, merupakan kasus yang jarang terjadi, karena literatur yang ada menunjukkan tidak ada hubungan yang jelas antara riwayat fistula kavernosa karotis ibu dan hasil janin. Meskipun ada kekhawatiran mengenai potensi kelainan janin dan risiko kanker dari terapi embolisasi endovaskular selama kehamilan, tindak lanjut pascapersalinan dengan angiografi pengurangan digital (DSA) lanjutan direncanakan.Simpulan: Kompleksitas pengelolaan multigravida dengan usia kehamilan 37 minggu dalam persalinan dengan fistula kavernosa karotis dan janin tunggal hidup dengan presentasi kepala, menekankan pentingnya pendekatan multidisiplin untuk luaran ibu yang optimal. Perlunya pendektanan multidispilin keilmuan memeberiksan hasil yanga baik pada ibu dan bayinya.Kata kunci: Fistula Kavernosa Karotis, Angiografi Pengurangan Digital

Prevalence and Distribution of Risk Factors for Preterm Labor in RSUP DR. Mohammad Hoesin Palembang Period January 1 2020 – December 31 2023 Beumaputra, Adyatma Utama; Martadiansyah, Abarham; Nurwany, Raissa; Mirani, Putri; Putra, Hadrians Kesuma
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 1 Maret 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i1.825

Objective: This study aims to determine the prevalence and distribution of risk factors for preterm labor.Methods: This is a descriptive observational study with a cross-sectional design. The data used in this study were secondary data obtained with the total sampling method from the medical records of Dr. Mohammad Hoesin Palembang Hospital from January 1, 2020 to December 31, 2023.Results: This study found 1,654 cases of preterm labor from January 1, 2020 to December 31, 2023. The analysis of risk factors among mothers indicated that those within the high-risk age categories (<20 years and >35 years) constituted 31.7%. Multiparous and grand multiparous women represented 41.7%, while multiple pregnancies accounted for 6.6%. A history of premature rupture of membranes was noted in 25.4% of cases, polyhydramnios was observed in 1.3%, and a history of cesarean delivery was found in 25.4%. Furthermore, 33% suffered from hypertension, and 2.5% had diabetes. Anemia was prevalent in 47.9% of the mothers, and infection was reported in 42.8%. A history of preterm delivery was noted in 13.7%, risky gestational distance was found in 10.6%, and 25% had a history of antepartum hemorrhage. Finally, obesity was observed in 14.5% of the mothers.Conclusion: The number of deliveries continued to decrease, but the prevalence of preterm labor increased from 2020 to 2023. Anemia is the most common risk factor found in mothers with preterm labor.Prevalensi dan Distribusi Faktor Risiko Persalinan Prematur di RSUP Dr. Mohammad Hoesin Palembang dalam Tiga TahunAbstrakTujuan: Penelitian ini bertujuan untuk mengetahui prevalensi serta distribusi faktor risiko persalinan prematur.Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross-sectional. Data yang digunakan dalam penelitian ini merupakan data sekunder dengan metode total sampling dari data rekam medik RSUP Dr. Mohammad Hoesin Palembang periode 1 Januari 2020 – 31 Desember 2023.Hasil: Terdapat 1654 kasus persalinan prematur dengan periode 1 Januari 2020 – 31 Desember 2023. Distribusi faktor risiko didapatkan ibu dengan usia berisiko (<20 tahun dan >35) tahun (31,7%), paritas multipara dan grandemultipara (41,7%), kehamilan multipel (6,6%), riwayat ketuban pecah dini (25,4%), polihidramnion (1,3%), riwayat persalinan sesar (25,4%), hipertensi (33%), diabetes (2,5%), anemia (47,9%), infeksi (42,8%), riwayat persalinan prematur (13,7%), jarak kehamilan berisiko (10,6%), riwayat perdarahan antepartum (25%), obesitas (14,5%). Kesimpulan: Jumlah persalinan terus mengalami penurunan, namun prevalensi kejadian persalinan prematur terus mengalami peningkatan dari tahun 2020-2023. Anemia menjadi faktor risiko paling banyak yang ditemukan pada ibu dengan persalinan prematur.Kata kunci: Prevalensi, Persalinan Prematur, Faktor Risiko

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