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All Journal Bulletin of Electrical Engineering and Informatics Majalah Obstetri dan Ginekologi Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) SRIWIJAYA JOURNAL OF MEDICINE Indonesian Journal of Perinatology
Putri Mirani
Faculty of Medicine University of Indonesia Dr. Cipto Mangunkusumo Hospital Jakarta
Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Majalah Obstetri dan Ginekologi

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The role of stem cells in obstetrics and gynecology: A systematic review Mirani, Putri; Legiran; Kesty, Cindy; Andrina, Hana
Majalah Obstetri & Ginekologi Vol. 31 No. 3 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I32023.129-138

Abstract

HIGHLIGHTS Stem cell technology has various roles in the field of obstetrics and gynecology, including fertility study as well as tissue damage repair. Safety profile of stem cells technology use in human still need to be assessed.   ABSTRACT Objective: This study aimed to review the role of stem cells in obstetrics and gynecology. Materials and Methods: This review used several databases, the PubMed, Wiley Online Library, and ScienceDirect to search open access original and review articles in English related to stem cells, obstetrics, and gynecology in the last 10 years. The results were analyzed qualitatively. Results: Out of 1,016 records identified through database searching, fifteen articles were eligible for review. Several articles reported the role of stem cells in endometrium repair. Stem cell can also increase endometrial thickness and increase the likelihood of pregnancy. In the field of gynecology, stem cells can be used as potential treatment for stress urinary incontinence and anal incontinence. Despite of all those abilities, stem cells might have errors, such as chromosomal abnormalities, epigenetic and genetic defect, which could potentially turn the stem cells into tumor initiating cells (TICs), thus can contribute to ectopic growth of endometrium (endometriosis), leiomyoma, leiomyosarcomas, and adeno-myosis. Conclusion: Stem cell technology has various roles in the field of obstetrics and gynecology, including fertility study as well as tissue damage repair. However, in-depth research to ensure the safety profile of stem cells technology use in human is necessary.
COVID-19 in pregnancy: Maternal and perinatal outcomes at Dr. Mohammad Hoesin Hospital, Palembang, Indonesia Martadiansyah, Abarham; Mirani, Putri; Ridwan, Metta Rania; Hartati; Andriyani Liberty, Iche; Stevanny, Bella
Majalah Obstetri & Ginekologi Vol. 33 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I12025.11-20

Abstract

HIGHLIGHTS COVID-19 increases the likelihood of adverse maternal outcomes throughout pregnancy, including pneumonia, cesarean section, and ICU admission. Prompt diagnosis and treatment of COVID-19 may improve maternal outcomes. COVID-19 does not increase the likelihood of adverse perinatal outcomes. Reassurance can be provided to expectant mothers.   ABSTRACT Objective: The objective of this study was to analyze the maternal and perinatal outcomes of COVID-19 in pregnancy at Dr. Mohammad Hoesin Hospital, Palembang, Indonesia. Materials and Methods: This retrospective cohort study was carried using medical records of pregnant mothers who delivered at Dr. Mohammad Hoesin Hospital Palembang from March 2020 to August 2021. The subjects were into two groups: pregnant women with and without COVID-19. Pearson Chi-Square test was used for bivariate analysis to determine the associations between COVID-19 and maternal as well as neonatal outcomes. The data were analysed using the Stata 15 statistical software. Multivariate analysis was done using the cox regression test to determine whether maternal characteristics affected those associations. P-value of < 0.05 were considered statistically significant. Results: The study analyzed 220 subjects, including 62 COVID-19-positive (28.18%) and 158 COVID-19-negative (71.82%) patients. Among expectant mothers with COVID-19, caesarean sections were the most common maternal outcome (82.26%), while fetal distress was the most frequent perinatal outcome (12.13%). Significant associations were found between COVID-19 and maternal outcomes, including pneumonia (RR = 12.76), caesarean section (RR = 2.74), and ICU hospitalization (RR = 6.90). These associations remained significant after adjusting for maternal characteristics. However, no significant association was found between COVID-19 and perinatal outcomes. Conclusion: COVID-19 increases the likelihood of adverse maternal outcomes throughout pregnancy.
Co-Authors Adnan Abadi, Adnan Agustria, Rizky Amir Fauzi Anang Ansyori Andrina, Hana Andriyani Liberty, Iche Ansyori, Muhammad Hatta Arjanggi, Kiagus Irawan Satria Awan Nurtjahyo Beumaputra, Adyatma Utama Darmawahyuni, Annisa Dian Palupi Rini HARTATI Iche Andriyani Liberty, Iche Andriyani Irfanuddin Jhonatan, Senna Moca Kesty, Cindy Krisna Murti Krisna, Ratih Legiran Legiran Mahadika, Febrinata Martadiansyah, Abarham Muhammad Naufal Rachmatullah Muhammad Taufik Roseno, Muhammad Taufik Nurwany, Raissa Nuswil Bernolian Pangemanan, Wim Theodorus PATIYUS AGUSTIANSYAH, PATIYUS Peby Maulina Lestari, Peby Maulina Prasetiyo, Muhammad Ath Thaariq Puspitasari, Dwi Cahya Putra, Hadrians Kesuma Ridwan, Metta Rania Rizani Amran Rizany, Selly Sapitri, Ade Iriani Saputra, Tommy Siti Nurmaini Stevanny, Bella Syamsuri, Ahmad Kurdi Syaputra, Hadi Theodorus Theodorus Usman, Fatimah Wim T. Pangemanan