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I Wayan Muderawan
Universitas Pendidikan Ganesha
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Journal : GANESHA MEDICINA

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KAJIAN TERHADAP KLAIM “ARAK BALI DAN KOPI CAMPUR ARAK SEMBUHKAN COVID-19” Muderawan, I Wayan; Giri, Made Kurnia Widiastuti; Budiawan, Made; Suja, I Wayan
Ganesha Medicina Vol. 1 No. 2 (2021)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (515.123 KB) | DOI: 10.23887/gm.v1i2.38386

Abstract

Covid-19 merupakan penyakit sistem saluran pernapasan yang disebabkan oleh genus β-coronavirus, severe acute respiratory syndrome coronavirus 2, dari famili Coronaviradae. Covid-19 dapat menular dari manusia ke manusia melalui kontak erat dan percikan cairan pada saat bersin dan batuk. Covid-19 menyebar dengan cepat ke seluruh dunia, dan berdampak pada sistem kesehatan dan sosial ekonomi masyarakat dunia. Virus korona penyebab Covid-19 sudah mengalami mutasi, menghasilkan varian yang sangat berbahaya, meliputi varian alpa, beta, gamma dan delta.Varian baru ini menyebabkan lonjakan kasus Covid-19.  Sampai saat ini belum ada obat anti virus korona yang dapat menyembuhkan Covid-19. Arak Bali dicampur dengan ekstrak daun jeruk purut (Citrus hystrix) dan minyak kayu putih (Eucalyptus) serta kopi canpur arak yang diklaim dapat menyembuhkan Covid-19, sampai saat ini belum terbukti dan tidak bisa diyakini kebenarannya. Ini merupakan klaim subjektif dan tidak didukung oleh data ilmiah.
Toxicological Evaluation of Ginger (Zingiber afficinale) and Kayu Secang (Biancaea sappan) Extracts using Brine Shrimp (Artemia Salina L.) Giri, Made Kurnia Widiastuti; I Wayan Muderawan
Ganesha Medicina Vol. 4 No. 2 (2024)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/gm.v4i2.85425

Abstract

Ginger (Zingiber oficinale) and sappan wood (Biancaeae sappan) are herbaceous plants that are commonly used as herbal decoctions. Due to their wide biological and pharmacological activity, many natural compounds can serve as the foundation for the creation of modern medicines. Some of them are also known to have toxicological characteristics that are important in the development of cancer drugs. Objective: This study aims to evaluate the toxic effects of secang wood extract (Biancaeae sappan) and ginger (Zingiber oficinale) on saltwater shrimp (Artemia salina L.).Methods:  The design of this study was a laboratory experimental analysis using the Brine Shrimp (Artemia Salina L.) method. The extract was prepared using standard methods and its toxicity was evaluated using a saltwater shrimp death test. Results: The results of the study were shown by determining its lethal concentration (LC50) which affects 50% of the shrimp population.  showed that ginger extract was very toxic to shrimp brine with an LC50 value of 12.91. This shows that both extracts have high toxicity and can have a good effect on cells undergoing carcinogenesis even at relatively low concentrations. Conclusion: These findings highlight the importance of careful use and proper handling of extracts to minimize the potential health risks associated with the toxicity of herbal extracts. Further research is needed to elucidate the specific components responsible for the observed toxicity and to explore the potential use of herbal extracts as anti-cancer and antioxidants.
Co-Authors Adiningsih, Made Darmaprathiwi Anggi Priliyanti Bgeholz, Susanne Daiwataningsih, Ni Ketut Prati Darma, I Dewa Gede Abi Dr. I Nyoman Tika,M.Si . Eky, Vicky Enggy Clovidea Indra Fenica, Istiqomah Frieda Nurlita Frieda Nurlita Gede Agus Beni Widana Gede Billy Oktavio Putra Hemayanti, Ketut Lia I Dewa Gede Abi Darma I Gusti Lanang Wiratma I Gusti Ngurah Bayu Sucitra I Gusti Ngurah Bayu Sucitra, I Gusti Ngurah Bayu I Ketut Supir I Komang Wisnu Budi Wijaya I Made Ary Sudiatmika I MADE KARTAMA . I Nyoman Sujana I Wayan Karyasa I Wayan Mudianta I Wayan Rai I Wayan Rai I Wayan Sadia I Wayan Suastra I Wayan Subagia I Wayan Suja Ida Ayu Kade Sastrika Istiqomah Fenica Ketut Lia Hemayanti Laksmi, Pande Putu Diah Suci Luh Lian Pertiwi Luh Mitha Priyanka Luh Putu Renis Ukirsari Made Budiawan Made Darmaprathiwi Adiningsih Made Kurnia Wiastuti Giri Made Kurnia Widiastuti Giri Marthen Reda Boro Matthiesen, Finn Mudianta, I Wayan Muthia Zahra Nabila N. Ramadiyanti Nabila, Muthia Zahra Ni Ketut Prati Daiwataningsih Ni Made Sih Widyasti Ni Putu Giyan Adnya Antari . NI PUTU MARHENI . Ni Putu Novi Puspitadesi Ni Putu Rahayu Kusuma Pratiwi Ni Putu Wulan Romianingsih Ni Putu Wulan Romianingsih Ni Wayan Martiningsih NI WAYAN NITA ULANTARI . NUR RAMADIYANTI . Nurlita, Frieda Pertiwi, Luh Lian Pratiwi, Ni Putu Rahayu Kusuma Priliyanti, Anggi Priyanka*, Luh Mitha Prof. Dr.I Nengah Suparta,M.Si . Puspitadesi, Ni Putu Novi Putra, Gede Billy Oktavio Putu Widiartini Ramadiyanti, N. Reda Boro, Marthen Romianingsih, Ni Putu Wulan Siti Maryam Sudiatmika, I Made Ary Ukirsari, Luh Putu Renis Vicky Enggy Clovidea Indra Eky Widiartini, Putu Widyasti, Ni Made Sih Young, David James