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All Journal Jurnal AGROTEKNOLOGI Innofarm Jurnal Inovasi Pertanian Health Notions JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Teknologi Pertanian Andalas J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Community Development Journal: Jurnal Pengabdian Masyarakat Journal SAGO Gizi dan Kesehatan Jurnal Riset Ilmiah
Septy Handayani
Program Studi Gizi, Fakultas Kesehatan Masyarakat, Universitas Jember
Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENGARUH STATUS GIZI TERHADAP FERTILITAS WANITA: LITERATURE REVIEW Rista Dwi Hermilasari; Septy Handayani; Nurul Ulya Luthfiyana
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 7 (2026): SINERGI : Jurnal Riset Ilmiah, Juli 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i7.2733

Abstract

Infertility is a reproductive health issue influenced by various factors, including nutritional status. Nutritional status is a modifiable determinant that plays an important role in the regulation and maintenance of reproductive function. Both undernutrition and overnutrition have the potential to affect female reproductive function through metabolic, hormonal, and inflammatory mechanisms. This study aimed to provide a comprehensive overview of the influence of nutritional status on female fertility. A literature review was conducted by searching articles in the Scopus, PubMed, and ScienceDirect databases using the keywords nutritional status, obesity, overweight, malnutrition, body mass index, female fertility, infertility, and reproductive health. The findings indicate that nutritional status has a complex relationship with female fertility. Increased adiposity and obesity may adversely affect reproductive function, including ovarian reserve, oocyte quantity, reproductive outcomes, and the risk of obstetric complications. In addition, relative fat mass has the potential to be a more sensitive indicator than body mass index for evaluating the risk of female fertility disorders. Therefore, the use of more comprehensive adiposity indicators is needed to improve the understanding of the relationship between nutritional status and female fertility.
Efek diet tinggi lemak terhadap berat testis dan kadar glukosa darah puasa tikus Wistar jantan Rista Dwi Hermilasari; Septy Handayani; Ellanda Rima Ervyanna
Jurnal SAGO Gizi dan Kesehatan Vol 7, No 2 (2026): Agustus
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v7i2.3138

Abstract

Background: Globally, modern lifestyle trends are characterized by increased consumption of high-fat food, which contribute to metabolic disorders. High-fat diets can also cause disorders in the male reproductive system. However, evidence regarding the association between changes in testicular weight and glycemic dysregulation as indicators of metabolic-reproductive disorders in animal studies remains limited.Objectives: This study aimed to evaluate the effect of high-fat diet on testicular weight and fasting blood glucose levels inmale Wistar rats.Methods: This study was conducted in June toJuly 2024 at the Basic Dentistry Laboratory, University of Jember using a randomized posttest-only control group design. A total of 14 male Wistar rats were divided into two groups: P1 (normal diet) and group P2 consisting of 2 ml of egg yolk given for 28 days. The rats were provided with drinking water ad libitum. Fasting blood glucose levels were measured using an Easy Touch GCU glucometer. After the rats were euthanized and dissected, testicular weight was measured using a digital scale with an accuracy of 0,1 g. Data were analyzed using an independent t-test with a significance value of p < 0.05.Results: Administration of a high-fat diet to male Wistar rats showed lower testicular weight compared with the normal diet group, but the difference was not statistically significant (p = 0.315).In contrast , administration of high-fat diet to Wistar rats showed a significant difference in fasting blood glucose levels compared the normal diet group (p < 0.001).Conclusion: A high-fat diet significantly increases fasting blood glucose levels, indicating impaired glucose homeostasis and potentially contributing to changes in testicular weight, which may disrupt reproductive function.
Co-Authors Abdul Azis Akbar Aji Sukoco Ana Islamiyah Syamila Andi Eko Wiyono, Andi Eko Aryatika, Karera Azifa Nur Hasanah Devi Arine Kusumawardani Dian Purbasari Ellanda Rima Ervyanna Eri Witcahyo Farida Wahyu Ningtyias Fuji Kurniawati Ginata Ayu Maulana Manik Nur Hidayati Muhammad Rivai Ninna Rohmawati Nurul Ulya Luthfiyana Oktafiani, Lirista Dyah Ayu Puspita Sari Ramadhan Taufika Rista Dwi Hermilasari Rofrofiyyah Ula Ruli Bahyu Antika Sartono Joko Santosa Septi Nur Rachmawati Triana Lindriati Yunita Satya Pratiwi