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All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Eureka Herba Indonesia Jurnal of Syiah Kuala Dentistry Society JDS (Journal of Syiah Kuala Dentistry Society)
Dohude, Gostry Aldica
Department Of Oral And Maxillofacial Surgery, Faculty Of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
Agriculture, Biological Sciences & Forestry Dentistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Effectiveness of Curcuma longa L on the growth Inhibition of Streptococcus sanguinis Dohude, Gostry Aldica; Rusdy, Hendry; Hanafiah, Olivia Avriyanti; Br Ginting, Rachel Adinda Yule
Journal of Syiah Kuala Dentistry Society Vol 8, No 1 (2023): June 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i1.33033

Abstract

Background: A dry socket is a severe pain one to three days after tooth extraction. Streptococcus sanguinis (S. sanguinis) is reported to inhibit the healing process of dry sockets. Curcuma longa L contains flavonoids, tannins, saponins, and alkaloids which have the potential as antibacterials. Objective. This study evaluated the antibacterial properties of Curcuma longa L. on the S. sanguinis. Materials and Methods: This experimental study used a post-test-only control group design. Turmeric leaf extract is made by using the maceration extraction method. The method used in the inhibition test used Kirby-Bauer disc diffusion with five samples for each treatment. The sample consisted of five treatment groups: turmeric leaf extract with concentrations of 10%, 15%, and 20%, and positive control (clindamycin) and negative control (DMSO) groups. Data were analyzed using the One Way ANOVA and Post Hoc tests. Results. The results of data analysis using ANOVA showed a p-value of 0.00 on inhibition, which means that turmeric leaf extract can inhibit the growth of S. sanguinis. The average inhibition zone obtained was 9.52 mm at a concentration of 10%, at a concentration of 15% at 9.84 mm, and at a concentration of 20% at 10.18 mm. Conclusion: Curcuma longa L extract inhibited the growth of S sanguinis on a moderate scale. Higher concentrations showed the best inhibition values.
Effects of 3% Mobe (Artocarpus lakoocha) leaf extract gel on the post-extraction socket: In-vivo study Hanafiah, Olivia Avriyanti; Hanafiah, Diana Sofiah; Dohude, Gostry Aldica; Satria, Denny; Putri, Maharani Syahnia; Harahap, Nurul Izzatunna Jhirah
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p102-109

Abstract

Background: Mobe (Artocarpus lakoocha) is recognized for its potential in accelerating wound healing, attributed to its secondary metabolites. However, its impact on hard tissue healing on post- extraction tooth sockets has been underexplored. Purpose: This study aims to analyze the effects of 3% Mobe leaf extract gel on the number of fibroblasts, osteoblasts, osteocytes and post-extraction sockets in Wistar rats. Methods: Thirty-two male Wistar rats had their left mandibular incisors extracted and were divided into eight groups. Mobe leaf extract gel was applied to Group I-IV and Aloclair® gel was applied to Group V-VIII for 14 days, twice a day. Residual socket volume (RSV) and fibroblast counts were measured on days 3, 7, and 14, while osteoblast and osteocyte counts were assessed on days 7, 14, and 28 post extraction. The RSV data were analyzed using repeated measures analysis of variance (ANOVA) and post-hoc least significant difference (LSD) test, while fibroblasts, osteoblasts, and osteocytes counts were analyzed with one-way ANOVA and post-hoc LSD tests. Results: RSV decreased significantly in both groups on day 14 (p=0.001 and p=0.002); however, the RSV was lower on the Mobe group. The fibroblast counts were higher in the Mobe group (p=0.001), and there was a significant difference in the mean number of osteoblasts and osteocytes in the Mobe group (p= 0.043 and p=0.008). Conclusion: The study concludes that 3% Mobe leaf gel extract is better than Aloclair® in accelerating socket healing mainly due to increased proliferation of fibroblasts, osteoblasts, and osteocytes.
Antibacterial Activity of Zanthoxylum acanthopodium DC. Extract Against Staphylococcus aureus: An In Vitro Study: Antibacterial Activity of Zanthoxylum acanthopodium DC Gostry Aldica Dohude; Ahyar Riza; Hendry Rusdy; Ribka Ulina Ritonga
Journal of Syiah Kuala Dentistry Society Vol. 10 No. 2 (2025): Vol 10 No. 2 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v10i2.862

Abstract

Dry socket is an acute inflammation of the alveolar bone around an extracted tooth due to the detachment of a blood clot. Staphylococcus aureus is one of the bacteria that plays a role in dry socket occurrence. Andaliman fruit (Zanthoxylum acanthopodium DC.) contains alkaloids, flavonoids, tannins, and triterpenoids/steroids that have potential as antibacterials. This study aims to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of andaliman fruit extract against Staphylococcus aureus in vitro. This type of research is a laboratory experiment with a post-test-only control group design. The andaliman fruit extract was made using maceration extraction. The antibacterial effectiveness test used the dilution method with 4 samples for each treatment. The samples consisted of seven treatment groups, namely andaliman fruit extract concentrations of 50%, 25%, 12.5%, 6.25%, 3.125%, positive control (Chlorhexidine gluconate 0.2%), and negative control (DMSO). MIC was determined by observing the turbidity of the solution while MBC was determined by counting the number of colonies that grew on agar media. he results showed that the 3.125% concentration of andaliman fruit extract was the first clear solution compared to the negative control. The number of colonies that grew in andaliman fruit extract concentrations of 50%, 25%, 12.5%, 6.25%, 3.125% was 111.50±16.010 CFU/mL; 266.50±15.588 CFU/mL; 369.75±38.266 CFU/mL; 489.75±49.688 CFU/mL; and 744.75±14.033 CFU/mL. Data were analyzed using the Kruskal-Wallis test which showed a p-value of 0.000. The andaliman fruit extract is effective as an antibacterial against Staphylococcus aureus with MIC 3.125% while MBC was not found
Co-Authors -, Ahyar Riza -, Ayu Lestari Ahyar Riza Allisha Tanzia Astri Suryani Pasaribu Saruksuk Ayuni HG, Afifah Br Ginting, Rachel Adinda Yule Cindy Audria Denny Satria, Denny Diana Sofia Hanafiah Harahap, Nurul Izzatunna Jhirah Hendry Rusdy Hendry Rusdy Hendry Rusdy Indra Basar Siregar Indra Basar Siregar Isnandar Isnandar Matondang, Siska Ella Natassa Olivia Avriyanti Hanafiah Olivia Avriyanti Hanafiah Preetypal Kaur JOHAL Putri, Maharani Syahnia Rachel Adinda Yule Br Ginting Rahmi Syaflida Dalimunte Ranu Putra Armidin Ribka Ulina Ritonga Ridho, Muhammad Fathur Rusdy, Hendry Sepriyani, Risa Siregar, Indra Basar Syaflida, Rahmi Tanandika, Janesia Tanzia, Allisha Wirsa, Dinda Andaru Zata Amani, A Rachma