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All Journal Biosfer: Jurnal Tadris Biologi BIOMA : Jurnal Biologi Makassar PENDIPA Journal of Science Education Jurnal Ilmiah Biologi UMA (JIBIOMA)
CHOIRUL MUSLIM
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Immunology & microbiology Mathematics Social Sciences Other

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Pengaruh Pemberian Ekstrak Kijing (Pilsbryoconcha exilis) Pada Pemulihan Kualitas Sperma Mencit (Mus musculus) Erna Yunita Sari; Bhakti Karyadi; Aceng Ruyani; Choirul Muslim
PendIPA Journal of Science Education Vol 3, No 1 (2019): FEBRUARY
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (411.582 KB) | DOI: 10.33369/pendipa.3.1.40-44

Abstract

ABSTRACT[Effect of Kijing Extract (Pilsbryoconcha exilis) on the Recovery of Sperm Quality in Mice (Mus musculus)]. This study aims to determine the effect of Pilsbryoconcha exilis extract on the quality of M. muscullus sperm. The approach used for the study was experiment with a complete randomized design model. In this study, 4 treatments and 5 replications were conducted, including treatment 1 which only administered aquades as control (P0), treatment 2 which only given paracetamol dose 250 mg / kg (P1), and treatment 3 given paracetamol dose 250 mg / kg and P. exilis extract dose 0,46 mg / g (P2) and treatment 4 given paracetamol 250 mg / kg and extract P. exilis 0,69 mg / g (P3). Technique of data analysis using qualitative descriptive and statistical test of One Way Annova parametry, and if obtained significant difference then continued statistic test of Smallest Real Difference. From the results of the study, it was found that P. exilis and paracetamol extract had no effect on sperm quality. Keywords: Sperm; M. muscullus; extract P. exilis; paracetamol.(Received August 14 , 2018; Accepted January 20, 2019; Published February 26, 2019) ABSTRAKPenelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak Pilsbryoconcha exilis terhadap kualitas sperma M. muscullus yang diberi parasetamol. Pendekatan yang digunakan untuk penelitian adalah eksperimen dengan model rancangan acak lengkap (RAL). Pada penelitian ini menggunakan 4 perlakuan dan 5 ulangan meliputi perlakuan 1 yang hanya diberikan aquades merupakan kontrol (P0), perlakuan 2 yang hanya diberikan parasetamol dosis 250 mg/kg bb (P1), dan perlakuan 3 yang diberikan parasetamol dosis 250 mg/kg bb dan ekstrak P. exilis dosisi 0,46 mg/g bb (P2) dan perlakuan 4 yang diberikan parasetamol 250 mg/kg bb dan ekstrak P. exilis 0,69 mg/g bb (P3). Teknik analisa data menggunakan deskriptif kualitatif dan uji statistik parametri One Way Annova, dan jika didapatkan perbedaan yang bermakna maka dilanjutkan uji statistic Beda Nyata Terkecil (BNT). Dari hasil penelitian diketahui pemberian ekstrak P. exilis dan parasetamol berepengaruh tapi tidak signifikan terhadap kualitas sperma. Kata Kunci: Sperma; M. muscullus; ekstrak P. exilis; parasetamol.
Variasi Pola Sidik Jari dan Pola Palmar pada Masyarakat Suku Rejang Bengkulu Resiliani, Tiara; Kamilah, Santi Nurul; Lestari, Dian Fita; Jarulis, Jarulis; Sipriyadi, Sipriyadi; Muslim, Choirul
Jurnal Ilmiah Biologi UMA (JIBIOMA) Vol 5, No 2 (2023): November
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/jibioma.v5i2.1775

Abstract

The Rejang tribe is one of the indigenous communities in Bengkulu. They are dispersed throughout several areas of Bengkulu, however, the majority of them live in the Rejang Lebong district. The Rejang tribe is classified as a Malayan Mongoloid race. Generally, every tribe has distinctive characteristics. These characteristics include language, culture, religion, and physical characteristics. The purpose of this study was to analyze the characteristics of the Rejang tribal community residing in Pematang Sapang village, North Bengkulu, with a focus on their fingerprint and palm patterns. Data was gathered from 100 individuals of the Rejang tribe, who fulfilled the inclusion criteria. The data was analyzed quantitatively. The study determined that there are three fingerprint patterns in the Rejang community, with the loop pattern being most prevalent at 59.8%. There are only two palmar patterns; normal and simian, with the normal pattern being dominant at 94.5%. Statistical analysis revealed no significant correlation between fingerprint or palmar patterns and sex. Furthermore, there was no observable relationship between fingerprint and palmar patterns.  The Rejang tribe is characterized by the prevalence of the loop patterns for fingerprints and the normal patterns for palmar.
PROFIL GARIS PALMAR DAN SUDUT AXIAL TRIRADIUS DIGITAL PADA SISWA BERKEBUTUHAN KHUSUS DI KOTA BENGKULU Kamilah, Santi Nurul; Manurung, Widya C.; Lestari, Dian Fita; Haryanto, Hery; Sipriyadi, Sipriyadi; Muslim, Choirul
BIOMA : JURNAL BIOLOGI MAKASSAR Vol. 9 No. 2 (2024): Bioma : Juli - Desember 2024
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Hasanuddin University

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Abstract

Each individual is unique, one of which is the palmar line pattern on the surface of the palm skin. Children with special needs from the Down syndrome tend to have a Simian pattern. The purpose of this study was to analyze the palmar line and the angle of Axial Triradius Digital (ATD) on the palms of special needs students from the deaf, deafblind, and physically disabled groups at Sekolah Luar Biasa (SLB) Negeri 1 Bengkulu City. This research was conducted in September-October 2021 using interview and direct data collection methods on students who met the inclusion requirements. The results indicated that three distinct palmar patterns were observed in the three groups of students. The most prevalent pattern was the normal pattern, which was observed in 84.8% of deaf students, 70.4% of retarded students, and 83.3% of disabled students. The ATD of 350-500 was the most prevalent angle for entire groups of students: 87% of the deaf students, 84.3% of the deafblind students, and 100% of the physically disabled students. Furthermore, the Chi-Square test demonstrated that there was no relationship between palmar line patterns, ATD angles, and the group of special needs students. Keywords: Axial Triradius Digital (ATD) angles, Palmar, Student with special needs
Histopathological Evidence of Nephrotoxicity in Mice Administered Arcangelisia flava (L.) Merr. Stem Extract from Enggano Island Nurul Kamilah, Santi; Muslim, Choirul; Hermawati, Ely; Maulana, Sherlo Adha; Fita Lestari, Dian; Sri Astuti, R.R.; Ezer Simanungkalit, Eben; Siti Fitri Andriyani, Eka; Ananda Putri, Dea
Biosfer: Jurnal Tadris Biologi Vol 17 No 1 (2026): Biosfer: Jurnal Tadris Biologi
Publisher : UNIVERSITAS ISLAM NEGERI RADEN INTAN LAMPUNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24042/biosfer.v17i1.27294

Abstract

Arcangelisia flava (L.) Merr., an endemic Indonesian forest plant, is traditionally consumed as an aphrodisiac by the Enggano Island community, yet its safety profile remains poorly documented. This study evaluated the nephrotoxic potential of A. flava stem extract using a murine model. Fifteen ICR mice were randomly assigned to a control group receiving distilled water and a treatment group receiving 200 mg/kg body weight of ethanolic stem extract orally for 14 days. Kidney tissues were processed for hematoxylin-eosin staining and semi-quantitative histopathological scoring. Compared with controls, treated mice showed higher damage scores in the glomerulus, proximal tubule, and distal tubule, along with a reduction in glomerular diameter. Histopathological findings included podocytopenia, widened Bowman’s space, proximal tubular brush border loss, apoptotic changes, and ablation of macula densa and distal tubular epithelial cells. These findings indicate nephrotoxic activity of A. flava stem extract and highlight the need for dosage standardization before use. Bukti Histopatologis Nefrotoksisitas pada Tikus yang Diberikan Arcangelisia flava (L.) Merr. Ekstrak Batang dari Pulau Enggano ABSTRAK: Arcangelisia flava (L.) Merr. merupakan tumbuhan endemik hutan Indonesia yang secara tradisional dimanfaatkan sebagai afrodisiak oleh masyarakat Pulau Enggano, namun aspek keamanannya masih belum terdokumentasi dengan baik. Penelitian ini bertujuan mengevaluasi potensi nefrotoksik ekstrak batang A. flava menggunakan model mencit. Sebanyak 15 ekor mencit jantan galur ICR dibagi acak ke dalam kelompok kontrol yang diberi akuades dan kelompok perlakuan yang diberi ekstrak etanol batang A. flava dosis 200 mg/kg bobot badan secara oral selama 14 hari. Jaringan ginjal diproses dengan pewarnaan hematoksilin-eosin dan dianalisis menggunakan skor kerusakan histopatologi semi-kuantitatif. Dibandingkan kontrol, kelompok perlakuan menunjukkan skor kerusakan lebih tinggi pada glomerulus, tubulus proksimal, dan tubulus distal, serta penurunan diameter glomerulus. Temuan histopatologi meliputi podositopenia, pelebaran ruang Bowman, hilangnya brush border tubulus proksimal, perubahan apoptosis, serta ablasi makula densa dan sel epitel tubulus distal. Hasil ini menunjukkan aktivitas nefrotoksik ekstrak batang A. flava.
Co-Authors ACENG RUYANI BHAKTI KARYADI Dea Ananda Putri, Dea Erna Yunita Sari Ezer Simanungkalit, Eben Fita Lestari, Dian Hermawati, Ely HERNANI - Hery Haryanto ICE PURNAMAWATI Jarulis Jarulis Kamilah, Santi Nurul Lestari, Dian Fita Manurung, Widya C. Maulana, Sherlo Adha Nurul Kamilah, Santi Resiliani, Tiara Sipriyadi Siti Fitri Andriyani, Eka Sri Astuti, R.R. Sumiyati -