Garuda - Garba Rujukan Digital

p-Index From 2020 - 2025

2.928

P-Index

This Author published in this journals

All Journal Media Kesehatan Masyarakat Indonesia Idea Nursing Journal BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan SEL Jurnal Penelitian Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Jurnal Sains Riset Jurnal Health Sains International Journal of Health Science (IJHS) Chimica Didactica Acta : Journal of Chemistry and Chemistry Education Kreativitas Pada Pengabdian Masyarakat (Krepa) JIPI (Jurnal IPA dan Pembelajaran IPA) Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Pengabdian Masyarakat

Yuni Rahmayanti

Universitas Abulyatama

Author-ID : 3293114

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 18 Documents Claim Missing Document

Claim Missing Document

Articles

1 2

IDENTIFICATION OF POTENTIAL ANTIVIRUS FROM Moringa oleifera LEAF AS MPRO SARS-COV-2 INHIBITOR: STUDY OF MOLECULAR DOCKING Zaimi Afandi; Yuni Rahmayanti; Rizarullah Rizarullah
Chimica Didactica Acta Vol 10, No 1: June 2022
Publisher : FKIP USK

Corona virus disease/COVID-19 is an acute respiratory infection caused by SARS-CoV-2 and has become a pandemic. COVID-19 can be prevented by efforts such as physical distancing, washing hands, using masks and self-isolation as well as regional isolation. Moringa is a plant that can be used both as food and medicine. The purpose of this study was to observe the activity of Moringa leaf compounds in inhibiting Mpro (main protease) SARS-CoV-2. Moringa leaf compounds tested were Gamma tocopherol, Benzyl glucosinolate and Chlorogenic acid. The compound was taken from pubchem, while Mpro SARS-CoV-2 (receptor) was obtained from the world protein bank with the PDB code 6W63. This research was conducted using the In Silico method and AutoDock Vina software was used for the tethering process. The results of gridbox optimization by re-tethering control ligands obtained RMSD results of 0.122 . The results showed free energy Gibbs (ΔG) Gamma tocopherol (-6.8 kcal/mol), Benzyl glucosinolat (-6.6 kcal/mol), and Chlorogenic acid (-7.0 kcal/mol) which indicated a stable inhibitory reaction of Moringa leaf compounds against Mpro SARS-CoV-2. Based on Lipinski's rules, the compounds from Moringa leaves tested were qualified to be used as herbal medicines to be used orally.

Gambaran Cemaran Bakteri Escherichia coli pada Jajanan di SDN 70 Banda Aceh Nonie Safira; Yuni Rahmayanti; Fia Dewi Auliani
MEDIA KESEHATAN MASYARAKAT INDONESIA Vol 22, No 4 (2023): MKMI
Publisher : Fakultas Kesehatan Masyarakat, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/mkmi.22.4.256-265

Latar belakang: Anak usia sekolah umumnya setiap hari menghabiskan sepertiga waktunya di sekolah, sehingga menyebabkan mereka menghabiskan waktu makan siangnya di sekolah. Adapun jenis jajanan yang dijajakan beraneka ragam dari mulai jajanan sehat maupun jajanan tidak sehat. Makanan sehat yang mempunyai gizi yang cukup, sedangkan makanan tidak sehat sudah terkontaminasi mikroba. Salah satu mikroba yang berbahaya bagi manusia pada makanan adalah bakteri Escherichia coli. Tujuan penelitian ini untuk mengetahui apakah terdapat cemaran bakteri Escherichia coli pada jajanan di SDN 70 Banda Aceh.Metode: Metode jenis penelitian ini adalah deskriptif. Penelitian ini menggunkana metode kuantitifikasi bakteri dengan Teknik MPN (Most Probable Number) dan TPC (Total Plate Count). Sampel dipilih dengan metode purposive sampling.Hasil: Hasil penelitian menunjukkan bahwa 3 sampel minuman yang diuji dengan metode MPN (Most Probable Number) melebihi batas maksimum. Sedangkan 6 sampel makanan yang diuji dengan meode TPC (Total Plate Count) dinyatakan masih dalam ambang batas.Simpulan: Hasil penelitian menunjukkan bahwa semua sampel minuman terkontaminasi bakteri Escherichia coli dan unutk makanan tidak terkontaminasi bakteri Escherichia coli.Kata kunci: jajanan sekolah, kontaminasi, Escherichia coli Title: Description of Contamination of Escherichia Coli Bacteria in Food at SDN 70 Banda AcehBackground: School-age children generally spend a third of their time at school every day, causing them to spend their lunch time at school. The types of snacks that are sold vary from healthy snacks to unhealthy snacks. Healthy food that has sufficient nutrition, while unhealthy food is contaminated with microbes. One of the microbes that are harmful to humans in food is Escherichia coli bacteria. The purpose of this study was to determine whether there was contamination of Escherichia coli bacteria in snacks at SDN 70 Banda Aceh.Method: This type of research method is descriptive. This study used a bacterial quantification method using MPN (Most Probable Number) and TPC (Total Plate Count) techniques. The sample was selected by purposive sampling method.Result: The results showed that 3 samples of drinks tested using the MPN (Most Probable Number) method exceeded the maximum limit. while 6 food samples tested with the TPC (Total Plate Count) method were declared to be still within the threshold. Conclusion: Showed that all drink samples were contaminated with Escherichia coli bacteria and food was not contaminated with Escherichia coli bacteria.Keywords: school snacks, contamination, Escherichia coli

Hubungan Pola Makan dan Perilaku Merokok Terhadap Penderita Gastritis di Puskesmas Kuta Baro Septia Nurrahmawati; Yuni Rahmayanti; Fauziah Hayati
MEDIA KESEHATAN MASYARAKAT INDONESIA Vol 22, No 3 (2023): MKMI
Publisher : Fakultas Kesehatan Masyarakat, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/mkmi.22.3.169-175

Latar belakang: Gastritis merupakan peradangan yang mengenai mukosa lambung. Penderita gastritis pada umumnya terjadi pada orang-orang dengan pola makan yang tidak teratur, kebiasaan mengonsumsi makanan pedas, asam, makanan instant, minum kopi, dan minuman berkarbonasi. Selain pola makan salah satu kebiasaan masyarakat Indonesia yang dapat ditemui hampir di setiap kalangan masyarakat adalah perilaku merokok. Rokok tidaklah menjadi hal baru dan asing lagi di masyarakat,baik laki-laki maupun perempuan, tua maupun muda. Penelitian ini bertujuan untuk mengetahui Hubungan Pola Makan dan Perilaku Merokok Terhadap Penderita Gastritis di Puskesmas Kuta Baro.Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain studi cross sectional. Penelitian ini dilakukan pada bulan Desember 2022 sampai Januari 2023 di poli umum Puskesmas Kuta Baro. Pengambilan sampel dengan menggunakan metode total sampling. Pengumpulan data dilakukan secara langsung melalui wawancara dan pengisian kuesioner oleh responden. Data hasil penelitian dianalisis dengan menggunakan uji statistik Chi-Square.Hasil: Hasil penelitian yang diperoleh dari 80 sampel yang terpilih dan kontrol berdasarkan uji statistik Chi-Square dimana nilai p-value = 0,734 dengan kesimpulan tidak terdapat hubungan pola makan dan perilaku merokok terhadap penderita gastritis.Simpulan: Tidak terdapat hubungan pola makan dan perilaku merokok terhadap penderita gastritis di Puskesmas Kuta Baro.Kata kunci: pola makan; perilaku merokok; penderita gastritis Title: Relationship of Diet and Smoking Behavior to Gastritis Sufferers at Kuta Baro Health CenterBackground: Gastritis is inflammation that affects the mucosa stomach. Sufferers of gastritis generally occur in people with a diet irregular, the habit of consuming spicy, sour, instant food, drink coffee, and carbonated drinks. In addition to eating patterns one habit Indonesian society that can be found in almost every society is smoking behavior. Cigarettes are not a new and foreign thing in society, either male or female, old or young.Method: This study is an observational analytic study by design cross sectional study. This research was conducted from December 2022 to January 2023 at the public polyclinic at the Kuta Baro Health Center. Sampling using total sampling method. Data collection was carried out directly through interviews and filling out questionnaires by respondents. Research data were analyzed with using the Chi-Square statistical test.Result: Research results obtained from 80 selected and control samples based on the Chi-Square statistical test where the p-value = 0.734 with conclusions There is no relationship between diet and smoking behavior on gastritis sufferers.Conclusion: There is no relationship between diet and smoking behavior gastritis sufferers at the Kuta Baro Health Center.Keywords: diet; smoking behavior; gastritis sufferers

Uji Aktivitas Antidiabetes Senyawa Baru Daun Yakon (Smallanthus sonchifolius) sebagai Inhibitor Enzim DPP-4: Studi in Silico Mangatur Riverson Sinurat; Yuni Rahmayanti; Rizarullah Rizarullah*
JIPI (Jurnal IPA dan Pembelajaran IPA) Vol 5, No 2 (2021): JUNE 2021
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jipi.v5i2.20068

Diabetes melitus merupakan gangguang kesehatan global yang menjadi perhatian penting untuk menemukan pencegahan dan terapi baru. Diabetes melitus dapat diobati menggunakan obat golongan inkreitin untuk menghambat kerja enzim DPP-4. Daun yakon (Smallanthus sonchifolius) merupakan tanaman herbal yang sering digunakan untuk mengobati berbagai penyakit dan diketahui memiliki turunan senyawa sekunder baru. Tujuan penelitian ini adalah mengetahui aktivitas senyawa baru daun yakon menginhibisi enzim DPP-4 berdasarkan energi dan ikatan kimia secara in silico. Senyawa baru daun yakon adalah turunan asam octadecatrienoic dan Benzyl glikosida. Senyawa tersebut diambil dari pubchem dan digambarkan kembali menggunakan chemdraw, sedangkan enzim DPP-4 (reseptor) didapat dari bank protein dunia dengan kode PDB ID: 3F8S. Penelitian ini dilakukan dengan metode In Silico dan perangkat lunak AutoDock Vina digunakan untuk proses penambatan. Hasil optimasi gridbox dengan melakukan penambatan ulang ligan kontrol diperoleh hasil RMSD sebesar 1.628 Å. Hasil penambatan molekuler dapat disimpulkan bahwa senyawa baru daun yakon berpotensi menghambat aktivitas enzim DPP-4 sebagai antidiabetes berdasarkan nilai energi bebas ΔG dan ikatan kimia. Interaksi yang terbentuk antara ligan dan reseptor tepat pada sisi aktif enzim DPP-4 yaitu Glu205, Glu206, Asn710, Tyr662, Arg125, Ser630, Phe357, Tyr666, Tyr547 dan Ser209. Interaksi yang terjadi antara ligan dan reseptor didominasi oleh ikatan hidrogen. Senyawa 13(R)-hydroxyoctadeca-(9E,11E,15Z)-trienoic acid (ligan 1), benzyl +alcohol 7-O-α-L-arabinopyranosyl-(1"→2')-β-D-glucopyranoside (ligan 2), 13(R)-Hydroxy-octadeca-(9Z,11E,15Z)-trienoic acid (ligan 3) memiliki nilai ΔG sebesar -6.2 kkal/mol, -7.7 kkal/mol dan -5.6 kkal/mol. Namun, Benzyl alcohol 7-O-α-L-arabinopyranosyl (1"→2')-β-D-glucopyranoside (ligan 2) lebih berpotensi menghambat enzim DPP-4 karena nilai energi bebas Gibbs (ΔG) dan ikatan kimia yang terbentuk lebih negatif dan stabil dibandingkan ligan 1 dan 3

Antiviral Potential of Eucalyptus Oil (Melaleuca cajuputi) as the Primary Protease Inhibitor of SARS-CoV-2 Revealed by Molecular Docking Yuni Rahmayanti; Rizarullah Rizarullah; M Rizki Fakhrurrazi
International Journal Of Health Science Vol. 2 No. 2 (2022): July: International Journal of Health
Publisher : Pusat Riset dan Inovasi Nasional

The disease caused by the Corona Virus has afflicted hundreds of millions of individuals. The virus that causes the disease is SARS-CoV-2. To treat a variety of ailments, the Indonesian population favours the usage of medicinal herbs. The 1,8- cineol, karyophyllene, limonene, α-terpineol, α-pinene, dan β-pinene chemicals are present in eucalyptus oil (Melaleuca cajuputi) used in traditional medicine. This research was undertaken in silico to investigate the efficacy of these drugs as SARS-CoV-2 Main Protease (Mpro) inhibitors. The 1,8- cineol, karyophyllene, limonene, α-terpineol, α-pinene, dan β-pinene chemicals were molecularly docked using AutoDock Vina. Berdasarkan hasil molecular docking diperoleh Gibbs free energy (ΔG) dari kariofilen (-5.6 Kkal/mol), 1,8-cineole (-5.2 Kkal/mol), α-terpineol (-5.0 Kkal/mol), α-pinen (-4.9 Kkal/mol), β-pinen (-4.9 Kkal/mol), dan limonen (-4.8 Kkal/mol). Based on the results, the molecular docking data on these compounds likewise demonstrated no RMSD value greater than 2 Å. It indicates that the connection between the receptor and ligand is stable and that the response can occur spontaneously. The active site of the Mpro enzyme is the amino acid residue, where the interaction between the receptor and ligand occurs. Based on the bioactivity test, it can be inferred that the 1,8- cineol, karyophyllene, limonene, α-terpineol, α-pinene, dan β-pinene chemicals have varying bioactivities on different pharmacological targets. Because they satisfy Lipinski's requirements, these chemicals can also be utilized as oral medications. In addition, the toxicity test demonstrated that the test ligands exhibited minimal toxicity.

Hubungan Dukungan Suami Dengan Pelaksanaan Inisiasi Menyusu Dini (IMD) Di Wilayah Kerja Puskesmas Seulimeum Kabupaten Aceh Besar Martina; Yuli Zuhkrina; Yuni Rahmayanti
Medic Nutricia : Jurnal Ilmu Kesehatan Vol. 3 No. 3 (2024): Medic Nutricia : Jurnal Ilmu Kesehatan
Publisher : Cahaya Ilmu Bangsa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5455/nutricia.v3i3.5603

IMD (Early Initiation of Breastfeeding) is a very important opportunity and must be given immediately to newborns by placing the baby on the mother's stomach. Breastfeeding starting with IMD makes a big contribution to reducing infant mortality. IMD can prevent 22% of infant deaths at the age of 28 months. This research aims to determine husband's support in implementing early breastfeeding initiation (IMD) in the Seulimeum Community Health Center Working Area, Aceh Besar Regency. This research is an analytical research with a cross sectional approach. Sample determination was carried out using Non-Random Sampling using the Accidental Sampling technique, namely all mothers giving birth in the Seulimeum Aceh Besar Community Health Center area from 20 June to 30 July 2024 with a total of 30 samples. The results of the research show that there is a significant relationship between husband's support and the implementation of early breastfeeding initiation (IMD) in the Seulimeum Community Health Center Work Area, Aceh Besar Regency. The conclusion is that there is a significant relationship between husband's support and the implementation of early breastfeeding initiation (IMD) in the Seulimeum Community Health Center Working Area, Aceh Besar Regency.

OPTIMALISASI DAPUR SEHAT YANG AMAN DAN BERGIZI DALAM UPAYA PENCEGAHAN STUNTING DI DESA LUBUK SUKON KECAMATAN INGIN JAYA KABUPATEN ACEH BESAR Yuli Zuhkrina; Yuni Rahmayanti; Martina; Lai Yin Ling; Lensoni
Kreativitas Pada Pengabdian Masyarakat (Krepa) Vol. 2 No. 8 (2024): Kreativitas Pada Pengabdian Masyarakat (Krepa)
Publisher : CV SWA Anugerah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.8765/krepa.v2i8.5605

Providing appropriate complementary foods when children are 6 months and older plays an important role in fulfilling children's nutritional intake. Malnutrition at the beginning of life will have an impact on the quality of human resources (HR) in the future. Children will experience growth failure. Nutrition problems for toddlers in Indonesia based on the 2018 Riskesdas are still very high, such as the prevalence of stunting in toddlers is 30.8%, the prevalence of very poor and very thin toddlers is 10.2% and obese toddlers are 8%. The nutritional status of toddlers can be caused by maternal knowledge, parenting patterns, food intake, exclusive breastfeeding and infectious diseases. One effort that can be made to support the provision of optimal nutritional intake is by increasing the knowledge and skills of mothers of toddlers in processing MPASI using local and diverse food ingredients in a good, practical and safe manner through education. The methods used in this education are lectures and questions and answers, and pretests and posttests are also carried out. As a result of the outreach and outreach, there was an increase in the number of mothers who had good knowledge about quality MP-ASI, namely from 17.31% to 75%. It is hoped that health workers can provide education about providing quality MP-ASI by utilizing local food sources and increasing material about nutrition as well as motivating mothers to maintain good and correct parenting patterns

PENDAMPINGAN STIMULASI LITERASI MELALUI STRATEGI MEMBACA BEBAS TERBIMBING (MBT) PADA ANAK-ANAK MIGRAN Tuti Marjan Fuadi; Yuni Rahmayanti; Riska Nasuha; Nabilla Aprilya; Saskia Putri
BESIRU : Jurnal Pengabdian Masyarakat Vol. 1 No. 10 (2024): BESIRU : Jurnal Pengabdian Masyarakat, Oktober 2024
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/qzm3ns24

Tidak sedikit anak-anak pekerja migran Indonesia di Malaysia tidak bisa bersekolah di lembaga pendidikan formal, dengan berbagai masalah dan penyebabnya. Sehingga anak-anak migran memilih lembaga pendidikan non formal untuk dapat memperoleh pendidikan. Salah lembaga pendidikan non formal yang membantu proses pembelajaran bagi anak-anak migran di Malaysia, khususnya di Kuala Lumpur adalah salah satunya Sanggar bimbingan Hulu Kelang. Pengabdian ini bertujuan melakukan pendampingan dan membantu stimulasi literasi melalui strategi membaca bebas terbimbing (MBT) pada anak-anak migran. Metode penelitian yang digunakan adalah kualitatif dengan memberikan pendampingan, menyusun kegiatan belajar dan mengajar serta menerapkan strategi membaca bebas terbimbing. Adapun lokasi Sanggar bimbingan Hulu Kelang jalan Changkat Permata No 2757 Tingkat 3, 53100 Kuala Lumpur, letak sanggar ini berada di lantai 3 sebuah kawasan pertokoan. Program yang dirancang dalam kegiatan pengabdian ini berjalan dengan lancar, strategi MBT dilaksanakan dengan sembilan tahapan mulai dari persiapan, pengantar, pemilihan bacaan, waktu membaca, monitoring, diskusi, refleksi tertulis, presensi dan berbagi serta evaluasi.

Co-Authors Aditya Chandra Cut Oktaviyana Denafianti Denafianti Dewi Karlina Rusly Fauziah Hayati Fia Dewi Auliani Fitrah Rizqi Qaedi Papilaya Fitria Fitria Galih Ramadhan Sifa Isfanda Isfanda Isfanda, Isfanda Jumal Husni Lai Yin Ling M Rizki Fakhrurrazi Mahmud Hary Pranggono Mangatur Riverson Sinurat Martina Miftahul Amalia Muhammad Fakhruri Nabilla Aprilya Nana Trebna Zulvia Nonie Safira Riska Nasuha Rizarullah, Rizarullah Saskia Putri Septia Nurrahmawati Syarifah Nora Andrianty Tuti Marjan Fuadi ulaiya fazira Yuli Zuhkrina Zaimi Afandi

Title Search

Found 18 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 18 Documents
Search