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STATUS GIZI PADA PENDERITA RETARDASI MENTAL (Studi di SLB Dharma Wanita Sidoarjo) Handayani, Ari Tri Wanodyo
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 7, No 2 (2010)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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Mental retardation or commonly known as Mental Retardation (RM) is characterized by general intelligence functions that are below average and is accompanied by reduced ability to adapt or behave in adaptive. As a result of the disorder can affect the growth and development. The purpose of this study was todetermine the nutritional status of patients with RM. This study is an observational analytic study with a cross-sectional data retrieval. The study population is students SLB Dharma Wanita Sidoarjo regency. Large study sample was 37 students were randomly taken proportionately based on the severity of the RM. The data retrieved are age, TB and BB. Further data are calculated using the nutritional status of index TB / U and BB / U based on the size of the Z-score WHO NCHS. Analysis of the data using Kruskal Wallis test followed by Mann-Whitney test. Statistical test results showed that there are significant differences in the examination of TB / U in 3 groups of RM. But on examination BB / U data analysis showed no significant difference. Furthermore, the data TB / U were analyzed again using the Mann-Whitney test and found that there are significant differences between mild to RM medium and heavy. There is no official standard measure of nutritional status of patients with RM, so that the measurement is compared to the size of the WHO standard. In anthropometry, most RM patients included in the normal range and tend to be obese. RM moderate and severe sufferers tend to be different, because the more complex as well etiology factors consequences thereof. There is a possibility RM or RM is experiencing severe disruption due to thelinear growth factor complex

UKURAN ANTHROPOMETRI ANAK SD PENDERITA GONDOK DI KABUPATEN JEMBER Handayani, Ari Tri Wanodyo
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 8, No 2 (2011)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Iodine is an essential element for humans. It is concentrated in the thyroid gland and become a vital component of thyroid hormones. Reduced concentration of iodine causes iodine deficiency disorders (IDD) are often called goiter. Thyroid hormone produced by the thyroid gland directly affect bone growth, bone maturation and physical height. Anthropometry is often used to measure the nutritional status of community. This study aims to determine the differences in anthropometry of goitrous and normal children.This study was an observational-analytic study with cross-sectional data. The sample was children of primary school, aged 72-90 months in the Sumbersari and Mayang subdistrict, Jember. Sample size was 100 people each group. The data collected was the degree of goiter (palpation method), physical height (using microtoise) and body weight (using a digital scale). The measurement results are also calculated based on the Z-score.Analysis of data using t-test.The results showed that average physical height of goitrous children was 113.53 Â± 5.20 cm and the value of Zscore was -1.28 Â± 0.98 SD. In non goitrous children average physical height was 117.59 Â± 8.40 cm and -0.94 Â± 1.41 SD (Zscore values). The average body weight of goitrous children was 18.5 Â± 3.40 kg and -0.97 Â± 1.13 SD (Z-score values). The average body weight of non goitrous children was 20.68 Â± 10.82 kg and -0.18 Â± 1.46 SD (Z-score values). T-test analysis results indicate the existence of differences in physical height and body weight in goitrous children and non goitrous children were significant. Physical height is associated with chronic malnutrition. Hypothyroidism in goitrous patients may reduce the secretion of T3 and T4 hormones, which are growth hormone. Decreasing it can inhibit accretion of linear growth (height) and becomes stunted. Chronic malnutrition that occurs in goitrous children may also predispose to nutritional balance disturbances occurred that resulted in acute malnutrition so the weight is low, as a result of decreased appetite, illness (eg diarrhea, respiratory infections), or due to lack of sufficient food is consumed

Efektivitas Ekstrak Black Garlic dalam Menghambat Pertumbuhan Candida albicans Ratih Iswari Ningtias; Dyah Indartin Setyowati; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 8 No 3 (2020): Volume 8 No. 3, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i3.12990

Black garlic has many properties naturally can be used as an antifungi. This study aims to determine the effectiveness of Black garlic extract in inhibiting the growth of Candida albicans and knowing the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of Black garlic extract against Candida albicans. This study used 5 groups of Black garlic extract concentration, namely 75%, 50%, 25%, 12.5%, and positive controls, with 5 replications. Extraction was carried out using maceration method with 96% ethanol solvent, while the antifungal test was carried out by liquid dilution method. MIC was determined by observing the turbidity and clarity of each test solution and compared to the control solution. MFC was determined by observing the presence or absence of fungi colonies growing on Sabouraud Dextrosa Agar (SDA) media after incubation for 24 hours. The results of the study carried out the Kruskall-Wallis test showed a significance value (p <0.05) which means that there were significant differences in all groups. In the Mann-Whitney test showed a significance value (p <0.05) which means there are differences between treatment groups. The conclusion is that Black garlic extract has the ability to antifungal with MIC at a concentration of 50% and MFC at a concentration of 75%.

Hubungan Tingkat Kebersihan Gigi dan Mulut dengan Karies pada Nelayan di Pesisir Pantai Watu Ulo Kabupaten Jember Yona Anindita; Kiswaluyo Kiswaluyo; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.8654

Activity to cleanse and refresh the teeth and mouth is oral hygiene. Caries and periodontal disease will occure if not treating well, so they need to do the treatment to maintain the oral health. Fishermen usually sail in the afternoon and return in the next morning, sometimes they stay in the sea for a day. This situation causes the lack of attention of oral hygiene and increases the occurrence of dental caries. Researcher interests to analyze the relationship of oral hygiene levels with the caries of fishermen at Dusun Watu Ulo, Sumberejo Village, Jember District, East Java. This study performs oral hygiene examination using OHI-S index and caries examination using DMF-T index. This study aimed to determine the relationship between the level of oral hygiene with caries in fishermen at the coast of Watu Ulo Beach, Jember District.This observational analytic research was conducted by cross sectional approach. The method for sampling used Cluster Sampling. he average score of OHI-S fishermen at Watu Ulo coastal Jember District was 3.90 (bad category) and the average DMF-T index score was 3.10 (medium category). There was a weak relationship between oral hygiene with caries. Keywords: Oral hygiene, Caries, OHI-S, DMF-T, Fishermen.

Kadar Kolesterol pada Mencit (Mus-Musculus) Diabetes Setelah Konsumsi Ekstrak Rumput Laut Coklat (Phaeophyta) Irene Fransiska; Didin Erma Indahyani; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 8 No 1 (2020): Volume 8 No. 1, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i1.11349

In the case of Diabetes Mellitus, it will trigger some changes in lipid metabolism and lipoprotein composition, one of them is cholesterol. Cholesterol is a lipid that plays an important role in the structure of cell membranes. Seaweed contains bioactive components of flavonoids which reduce cholesterol levels. Brown seaweed contains bioactive components of alkaloids, flavonoids, triterpenoids, saponins, phenol hydroquinone, tannins, chlorophyll and β-carotene pigments. The bioactive component of brown seaweed also has strong antioxidant activity that can prevent damage caused by oxidative stress on pancreatic β cell function and acts as a trap for various free radicals and can reduce diabetic rat lipid peroxidation. This study to analyze the effect of giving brown seaweed extract on cholesterol levels in diabetic mice.This study was divided into 4 sample groups, namely the normal group, negative controls (diabetic mice), positive controls (diabetic mice + 1.3 mg / 20 gr BB metformin), K1 (diabetic mice + brown seaweed extract). The seaweed dose of 10mg / 20grBB is given on a daily basis for 21 days. Checking blood cholesterol levels in serum using the POD CHOD method and measured using biolysers. Diabetic mice with brown seaweed extract were significantly (p <0.05) lower cholesterol level of 68.94 mg / dL than diabetic mice 81.75 mg / dL. It was concluded that brown seaweed extract had an effect on reducing total cholesterol levels in diabetic mice. Keywords : Cholesterol levels, Diabetic mice, Brown Seaweed

NOVEL METHOD THYROID HORMONE MEASUREMENT Ari Tri Wanodyo Handayani
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Iodine is an essential mineral of thyroidhormones produced by the thyroid gland. These areessential for life which therefore, makes iodinecrucial. Although goiter is the most visible sequelaeof iodine deficiency, the major impact ofhypothyroidism due to iodine deficiency (1). Thereare 2 billion people are at risk of goiter due toinsufficient intake of iodine. Nearly 266 millionschool-aged children world-wide have insufficientiodine intake (2). The school children formedrepresentative study population for iodine statusestimation as they represent community (3).Decreased thyroid hormones levels(hypothyroidism), by contrast, is associated withdecreased metabolic rate. Most of these effects aredue to the direct action of thyroid hormones ontarget tissues and direct actions on genes expression(4).Thyroid stimulating hormone (TSH),secreted by the anterior pituitary in response tofeedback from circulating thyroid hormone. TSHregulates iodide uptake mediated by thesodium/iodide symporter, followed by a series ofsteps necessary for normal thyroid hormonesynthesis and secretion. Thyroid hormone isessential for normal development, growth, neuraldifferentiation, and metabolic regulation (5).Although the presence of thyroid hormoneis crucial, it has not become part of a routine checkup on the public service because it is costly. Centralpublic health laboratory does not serve the thyroidhormone tests (6). Besides, blood test to measurethyroid hormone is considered quite painful. Lately,research on oral fluid (saliva) which can be used asthe unit of test analysis emerged. saliva can be seenin many cases as a reflection of the physiologicalfunction of the body. There have been concernsabout the use of saliva for diagnostic purposes dueto its low concentration of analytes in comparison toblood (7). However, the examination of the thyroidhormones using saliva have not been used. Thepresent investigation was aimed to analyze thethyroid hormone assays using saliva.MATERIAL AND METHODSThe research was an experimental laboratory. Theused animals were male Wistar rats aged 10-11weeks as many as 21 rats which were divided into 3groups. K was control group which received the 6-week standard food and drink. P1 was the firsttreatment group (iodine deficiency) which receivedPTU (6mg/kg/BW) using intragastric intubationmethod for 6 weeks. P2 was the second treatmentgroup which received PTU (6mg/kg/BW) usingintragastric intubation method for 6 weeks followedby Levothyroxine (10μg/100mg/BW) administrationusing the same method for 4 weeks. At the end ofthe study, saliva and blood of rats was taken andthen the rats were sacrificed. The specimen wereexamined for the levels of T3, T4, TSH using ELISAprocedure using Rat U-T3 (UltrasensitivityTriiodothyronine) kit, Catalog No: E-EL-R1050(Elabscience); Rat T4 (Thyroxine) kit, Catalog No: EEL-R0981 (Elabscience); and Rat TSH (ThyroidStimulating Hormone) kit, Catalog No: E-EL-R0976(Elabscience). The data were collected andstatistically analyzed using ANOVA Mutivariate.

Oral health profile of the elderly people in the Pandalungan community Amandia Dewi Permana Shita; Zahreni Hamzah; Zahara Meilawaty; Tecky Indriana; Ari Tri Wanodyo Handayani; Dyah Indartin Setyowati
Dental Journal (Majalah Kedokteran Gigi) Vol. 53 No. 4 (2020): December 2020
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v53.i4.p217-222

Background: The Pandalungan community is a unique community established through the assimilation of two dominant cultures: the Javanese and Madurese. Both of these communities created a community with a new culture called the Pandalungan community culture. The people of this community live in coastal, rural and urban areas. Generally, research on the uniqueness in the oral health behaviour of the Pandalungan community has not been conducted since the oral health practices of the Pandalungan community are considered to be the same as that of the Javanese community. Purpose: In order to develop programmes for oral health prevention, this research aims at comparing the oral health profiles of the elderly (classified as per age) living in the rural and urban areas in the Jember Regency. Methods: The research employs a cross-sectional approach. The subjects of the research were selected on the basis of the total number of elderly people who attended the monthly meetings of the Karang Werda (those not willing to participate in the study were excluded). The study was conducted by organising extensive interviews, performing observations and intraoral examinations. Each group was classified into three subgroups on the basis of age: pre-elderly, elderly and high-risk elderly. The intraoral examination conducted included the oral hygiene index-simplified (OHI-S), the number of teeth missing, the depth of the pocket and the number of all functional tooth units (all-FTU). Results: The oral health profile of people in the rural community was poor when compared to the oral health profile of people living in the urban community (by accounting for nearly all the variables in the examination). Conclusion: The oral health profile of the elderly people in the Pandalungan community was poor. Adequate prevention and care are essential to maintain the oral health of people in the Pandalungan community.

STATUS GIZI PADA PENDERITA RETARDASI MENTAL (Studi di SLB Dharma Wanita Sidoarjo) Ari Tri Wanodyo Handayani
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 7 No 2 (2010)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Mental retardation or commonly known as Mental Retardation (RM) is characterized by general intelligence functions that are below average and is accompanied by reduced ability to adapt or behave in adaptive. As a result of the disorder can affect the growth and development. The purpose of this study was todetermine the nutritional status of patients with RM. This study is an observational analytic study with a cross-sectional data retrieval. The study population is students SLB Dharma Wanita Sidoarjo regency. Large study sample was 37 students were randomly taken proportionately based on the severity of the RM. The data retrieved are age, TB and BB. Further data are calculated using the nutritional status of index TB / U and BB / U based on the size of the Z-score WHO NCHS. Analysis of the data using Kruskal Wallis test followed by Mann-Whitney test. Statistical test results showed that there are significant differences in the examination of TB / U in 3 groups of RM. But on examination BB / U data analysis showed no significant difference. Furthermore, the data TB / U were analyzed again using the Mann-Whitney test and found that there are significant differences between mild to RM medium and heavy. There is no official standard measure of nutritional status of patients with RM, so that the measurement is compared to the size of the WHO standard. In anthropometry, most RM patients included in the normal range and tend to be obese. RM moderate and severe sufferers tend to be different, because the more complex as well etiology factors consequences thereof. There is a possibility RM or RM is experiencing severe disruption due to thelinear growth factor complex

UKURAN ANTHROPOMETRI ANAK SD PENDERITA GONDOK DI KABUPATEN JEMBER Ari Tri Wanodyo Handayani
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 8 No 2 (2011)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Iodine is an essential element for humans. It is concentrated in the thyroid gland and become a vital component of thyroid hormones. Reduced concentration of iodine causes iodine deficiency disorders (IDD) are often called goiter. Thyroid hormone produced by the thyroid gland directly affect bone growth, bone maturation and physical height. Anthropometry is often used to measure the nutritional status of community. This study aims to determine the differences in anthropometry of goitrous and normal children.This study was an observational-analytic study with cross-sectional data. The sample was children of primary school, aged 72-90 months in the Sumbersari and Mayang subdistrict, Jember. Sample size was 100 people each group. The data collected was the degree of goiter (palpation method), physical height (using microtoise) and body weight (using a digital scale). The measurement results are also calculated based on the Z-score.Analysis of data using t-test.The results showed that average physical height of goitrous children was 113.53 ± 5.20 cm and the value of Zscore was -1.28 ± 0.98 SD. In non goitrous children average physical height was 117.59 ± 8.40 cm and -0.94 ± 1.41 SD (Zscore values). The average body weight of goitrous children was 18.5 ± 3.40 kg and -0.97 ± 1.13 SD (Z-score values). The average body weight of non goitrous children was 20.68 ± 10.82 kg and -0.18 ± 1.46 SD (Z-score values). T-test analysis results indicate the existence of differences in physical height and body weight in goitrous children and non goitrous children were significant. Physical height is associated with chronic malnutrition. Hypothyroidism in goitrous patients may reduce the secretion of T3 and T4 hormones, which are growth hormone. Decreasing it can inhibit accretion of linear growth (height) and becomes stunted. Chronic malnutrition that occurs in goitrous children may also predispose to nutritional balance disturbances occurred that resulted in acute malnutrition so the weight is low, as a result of decreased appetite, illness (eg diarrhea, respiratory infections), or due to lack of sufficient food is consumed

Profil Kesehatan Gigi dan Mulut Berdasarkan Standar WHO pada Masyarakat Kecamatan Kaliwates Kabupaten Jember Chintya Monica Amelinda; Ari Tri Wanodyo Handayani; Kiswaluyo Kiswaluyo
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 19 No 1 (2022)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v19i1.30700

Indonesia's oral and dental health problems are quite high, including in Kaliwates Subdistrict. The newest method for looking at oral and dental health conditions operates WHO standard dental and oral health forms. Oral health data can be used as preventive, curative, and rehabilitative measures. The aim of this study was to determine oral health profile based on WHO standards in Kaliwates Subdistrict, Jember Regency. The research conducted was a descriptive observational with the cross-sectional approach by multiple clusters random sampling. The respondents were 97 people who stayed in Kaliwates and were 35-44 years old. Examination based on WHO standard dental and oral health form included dentition status, periodontal status, loss of attachment, email fluorosis, dental erosion, oral mucosal lesion, intervention urgency, and denture status. Data was processed based on each variable using the SPSS frequency distribution and presented in the table. Oral and dental health features were crown caries (99%) and roots (8.2%), restoration with caries (13.4%) and without caries (14.4%), extracted due to dental caries (38.1%) and other causes (3.1%), fixed prosthesis (2.1%), unerupted tooth (67%), fissure sealant (0%), gingival bleeding (72.2%), pocket 4- 5 mm (55.7%) and ≥ 6mm (1%), attachment loss of 0-3 mm (46.4%) and 4-5 mm (53.6%), very mild fluorosis (1%), enamel erosion (16, 5%) and dentin (3.1%), oral mucosal lesions ie other lesions (2.1%), need for non-urgency treatment (95.9%), and removable dentures (3.1%). Oral health profile based on WHO Standards in Community of Kaliwates Subdistrict showed some cases of oral disease that wasn’t need urgency treatment.

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