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All Journal Indonesian Journal of Applied Sciences Martabe : Jurnal Pengabdian Kepada Masyarakat PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) Jurnal Mandala Pharmacon Indonesia Reswara: Jurnal Pengabdian Kepada Masyarakat Vivabio : Jurnal Pengabdian Multidisiplin ACROPORA: Jurnal Ilmu Kelautan dan Perikanan Papua Jurnal Pengabdian Papua Jurnal Farmasi Sains dan Praktis JURNAL BIOLOGI PAPUA Jurnal Farmasi Indonesia
Rusnaeni Rusnaeni
Universitas Cenderawasih
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Journal : JURNAL BIOLOGI PAPUA

 1 
Aktivitas Antikoagulan dari Tumbuhan Kayu Ular (Strychnos lucida R.Br.) Elsye Gunawan; Aris A.L. Toruan; Rusnaeni Rusnaeni; Felycitae E. Appa
Jurnal Biologi Papua Vol 14, No 2 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.726 KB) | DOI: 10.31957/jbp.1494

Abstract

The stem of the snakewood plant (Strychnos lucida) has been used empirically as a malaria drug, relieves fever, treats stomach pain, hemorrhoids, rheumatism, stroke symptoms, and improves blood circulation. Tannins as one of the secondary metabolites of snakewood stems contain gallic acid compounds which are known to thin the blood. The purpose of this study was to determine the anticoagulant activity of the ethanolic extract of snakewood stems on blood group samples, namely A, B, AB, and O. The method used for extraction was maceration, for testing anticoagulants used method modified Lee-White and blood smears, as well as for data analysis carried out descriptively. The results obtained by the Lee-White modification method on blood group samples were visually not clotting. For anticoagulant activity by blood smear method, it was shown that microscopically snakewood bark extract prevented the presence of blood clots which could be observed with unrelated blood cells, intact and separated from each other.Key words: S. lucida; Lee-White modification; blood smear; anticoagulants
Uji Perbandingan Penetapan Kadar Sediaan Tablet Allopurinol 300 mg Generik dengan Nama Dagang Beredar di Distrik Sentani, Jayapura Rusnaeni Rusnaeni; Eva S. Simaremare
Jurnal Biologi Papua Vol 11, No 1 (2019)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.124 KB) | DOI: 10.31957/jbp.770

Abstract

Allupurinol is a medicine to treat gout especially to minimize the quantity of uric acid inside human blood. This study aims to understand the quality of gout drugs particularly the standard of Allupurinol between generic 300 mg and others Allupurinol tablet in retails at Jayapura Regency. Survey method has been used and samples were collected from Sentani district, Jayapura Regency. Spectrophotometer was used to determine the rate of Allupurinol. The results proved that in Allupurinol generic (A) the rate was 100.28% and generic (B) was 99.044%. For others tablet non generic with naming (a) the rate of Allupurinol as 99.46% while (b) was 100.77%. It means the averages of Allupurinol contain in generic was 99.6% and non-generic was 100.12%. According to Indonesian Farmakope Manual 4th Edition, the rate of Allupurinol contains in a drug must be 93.0% for minimum and can’t be more than 107.0%. Our study shown that Allupurinol generic with (A) label and non-generic with (b) label are based on the Indonesian Farmakope Standard 4th Edition.  Key words: Tablet Allopurinol, Penetapan generik, Jayapura.  
Co-Authors Allowisya Futwembun Andre Anusta Barus Aris A.L. Toruan Claudius Hendraman B. Tobi D. Pratiwi, Rani David W. Rumanasen Desy Ilmawati Sinaga Dina Ayomi Elfride Irawati, Elfride Elsye Gunawan Febrianty, Silva Dewi Febriyanti, Christine Felycitae Ekalaya Appa Fitria Lanuru G. Kendenan, Bryan Graciano Aristides Maturbongs Imelda Meriyanti Payungallo Irene Sondang Lingga Irpa, Makdalena Is Ika Ulfiani J. S. Sipahelut, Vrysel Juniarto Mende Krisna Dewi Krisna Dewi, Krisna Muayyidah, Nurita A. S. Mustika Endah Pratiwi Nur Fadilah Bakri Nurhidayah, Annisa Parandan, Ronald R. Reniurwarin, Sulis Rani Dewi Pratiwi Rosa, Stella S. Lingga, Irene Sarhana Sarhana Rassya Aulyah Said Soltief, Sitti Nurdjaja Suthelie, Chinry Charolina T. R. Setyoningrum, Retno Ulva, Dea A. Yohana Krisostoma Anduk Mbulang