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All Journal Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Majalah Kesehatan FKUB Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan JOMIS (Journal of Midwifery Science) Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Diponegoro International Medical Journal (DIMJ) Jurnal Ilmiah Kesehatan Jiwa
Innawati Jusup
Department Of Psychiatry, Faculty Of Medicine, Diponegoro University
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Hubungan Mekanisme Koping dengan Skor Depresi dan Risiko Bunuh Diri pada Orang dengan Gangguan Kepribadian Ambang Natalia Dewi Wardani; Alifiati Fitrikasari; Innawati Jusup; Titis Hadiati; Widodo Sarjana AS; Hang Gunawan Asikin; Tanjung Ayu Sumekar; Kezia Natalia Daniast Susilo; Diana Atmaja
Majalah Kedokteran Indonesia Vol 76 No 1 (2026): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.76.1-2026-1825

Abstract

Introduction: Borderline Personality Disorder (BPD) is associated with a high prevalence of depressive symptoms and an increased risk of suicidal behavior. Approximately 75% of individuals with BPD have attempted suicide, while self- injurious behavior occurs in 17% of young adults and 6% of the general adult population. Psychological stress and coping mechanisms play important roles in these outcomes.Methods: This cross-sectional quantitative study included 80 patients diagnosed with BPD. Coping strategies were assessed using the Brief COPE questionnaire and categorized into problem-focused or emotion-focused coping. Depression severity was measured using the GRID Hamilton Depression Rating Scale (GRID HAM-D), and suicide risk was assessed using the Columbia-Suicide Severity Rating Scale (C-SSRS). Coping strategies were subsequently categorized into problem-focused coping or emotion-focused coping based on the participant’s predominant response patterns.Results: Problem-focused coping showed a significant positive correlation with suicide risk (p = 0.002; r = 0.386). In contrast, emotion-focused coping demonstrated a significant negative correlation with suicide risk (p = 0.044; r = −0.479). Neither coping strategy was significantly associated with depression scores (p = 0.786 and p = 0.121, respectively).Conclusion: Problem-Focused Coping is associated with increased suicide risk behavior, while Emotion-Focused Coping is associated with lower levels of suicide risk behavior.
The Effect of Folic Acid Supplementation on the Liver Function in Chronic Schizophrenia Patients Alifiati Fitrikasari; Julianata Asady; Innawati Jusup; Hang Gunawan Asikin
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 17 No 2 (2023): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v17i2.5941

Abstract

Oxidative stress caused by free radicals and long-term antipsychotic use in chronic schizophrenic patients may result in liver cell damage and impaired liver function. Folic acid is an exogenous antioxidant that can boost the antioxidant defense mechanism (Glutathione Reductase), lowering free radicals and improving liver function. Determine the correlation between adjuvant folic acid and liver function in chronic schizophrenic patients. This was a placebo-controlled, double-blinded randomized control trial. The study sample included 36 patients in the control group and 36 patients in the treatment group. Subjects were patients who had suffered from schizophrenia for at least 2 years and received antipsychotics. Research subjects in the treatment group received folic acid supplementation. The intervention was conducted for 21 days during hospitalization. The level of AST (U/L) and ALT (U/L) was measured before and after supplementation. Following folic acid supplementation, AST levels were significantly improved (26.950 U/L compared to prior to treatment 33.09 U/L, p= <0.001). ALT levels after treatment were increased but there was no significant difference observed (p= 0.835). Folic acid supplementation improves AST levels significantly.
CORRELATION BETWEEN STRESS AND ANXIETY AND ACADEMIC BURNOUT AMONG FIRST-YEAR MEDICAL STUDENTS AT DIPONEGORO UNIVERSITY Salsabila Dewi Febrianti; Hang Gunawan; Widodo Sarjana; Innawati Jusup
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 15, No 5 (2026): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v15i5.53413

Abstract

Background: Entering university is a critical transition for first-year students, marked by numerous academic, social, and personal adjustments. Navigating these changes requires substantial mental resilience. Failure to adapt may lead to psychological strain, particularly stress and anxiety, which can escalate into academic burnout. Medical students are at higher risk than other undergraduates. Objective: To analyze the relationship between stress, anxiety, and academic burnout among first-year medical students. Methods: This analytical cross-sectional study involved 81 first-year medical students from the Faculty of Medicine, Diponegoro University. Participants were recruited through purposive sampling. Stress levels were assessed using the Perceived Stress Scale (PSS), anxiety was measured with the Beck Anxiety Inventory (BAI), and academic burnout was evaluated using the Maslach Burnout Inventory–Student Survey (MBI-SS). Descriptive statistics were applied to present frequency distributions, while correlations were examined using Spearman’s rank and Lambda tests. Results: Most participants experienced moderate stress (55.6%), mild anxiety (60.5%), and moderate academic burnout (48.1%). Stress was very strongly correlated with academic burnout (r = 0.799, p < 0.001), while anxiety showed a strong correlation (r = 0.597, p < 0.001). Conclusion: Stress and anxiety were both significantly associated with academic burnout in first-year medical students. Stress exhibited a very strong positive relationship, whereas anxiety demonstrated a strong positive association. These findings highlight the importance of early intervention strategies to reduce stress and anxiety, while also underscoring the need for stress management and mental health support programs tailored to early-year medical students to mitigate burnout risk.
Co-Authors Ainun Rahmasari Gumay Alifiati Fitrikasari Alifiati Fitrikasari Alifiati Fitrikasari Andrew - Johan Bantar Suntoko Devina Afraditya Paveta Diana Atmaja Djuara P Lubis Fanti Saktini Fulyani, Faizah Gianina Dinda Pamungkas Hang Gunawan Hang Gunawan Asikin Hang Gunawan Asikin Hardian Hardian Heny Puspita Sari Ichdinavia Harsaya Julianata Asady Kezia Natalia Daniast Susilo Liko Maryudhiyanto Linda Kartika Sari Lusiana Batubara Mohammad Sulchan Muchlis Achsan Udji Sofro Natalia Dewi Wardani Natalia Dewi Wardani Prima Kusumastuti Putri Theresia Lemmo Ate Bancin Rani Rahayu Regina Oktavia Rihadini Salsabila Dewi Febrianti Soesmeyka Savitri Tanjung Ayu Sumekar Tanjung Ayu Sumekar Tanjung Ayu Sumekar Tanjung Ayu Sumekar Titis Hadiati Titis Hadiati Titis Hadiati Tommy Raharja Tommy Raharja Widodo Sarjana Widodo Sarjana AS