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All Journal Jurnal Keperawatan Indonesia Jurnal Penelitian Kesehatan Suara Forikes Jurnal Keperawatan Silampari International Journal of Nursing and Health Services (IJNHS) Faletehan Health Journal Human Care Journal Real in Nursing Journal Jurnal Riset Kesehatan Nasional Jurnal Ners Jurnal Persatuan Perawat Nasional Indonesia (JPPNI) Journal of Telenursing (JOTING) Indonesian Journal of Global Health research Jurnal Menara Medika Nursing Sciences Journal Jurnal Ipteks Terapan : research of applied science and education JRKN Jurnal Nurse Jurnal Sahabat Keperawatan Malahayati International Journal of Nursing and Health Science Holistik Jurnal Kesehatan Indonesian Journal of Global Health Research
Dikha Ayu Kurnia
Fakultas Ilmu Keperawatan, Universitas Indonesia
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Efektivitas terapi komplementer alami untuk uremic pruritus: A systematic review Estefania Dos Santos; Riri Maria; Dikha Ayu Kurnia
Hik Vol. 20 No. 3 (2026): Volume 20 Nomor 3
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v20i3.2747

Abstract

Background: Uremic pruritus is an inflammatory skin condition that is a common problem among patients with chronic kidney disease (CKD), particularly those undergoing hemodialysis Purpose: To determine the effectiveness of natural topical complementary therapies in reducing uremic pruritus. Method: This literature review utilized the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The article search was designed using the PICOS framework: P (problem, patient, or population), I (intervention, prognostic factor, or exposure), C (comparison or control), O (outcome), and S (study). The literature search was conducted using ClinicalKey, ClinicalKey for Nursing, ProQuest, ScienceDirect, Scopus, EBSCOhost, Taylor & Francis, and Wiley, resulting in the extraction of 8 relevant and usable articles. Results: A total of 8 articles met the inclusion criteria. Nine types of natural ingredients were identified: violet oil, cannabis, Ziziphus jujube, Anethum graveolens (dill), sesame oil, Avena sativa, ostrich oil, and almond oil. These interventions were administered with and without manipulation. The studies showed a significant reduction in pruritus intensity (p < 0.05), with the most common administration method being topical application twice daily for 2–4 weeks. Additional benefits such as improvement in dry skin, sleep quality, and quality of life were also reported. No significant side effects were found. Conclusion: Natural topical complementary therapies are effective, safe, and well-tolerated in alleviating uremic pruritus in patients with chronic kidney disease (CKD) and those undergoing hemodialysis. Plant-based extracts are preferred due to their ease of extraction and patient acceptance. These therapies can serve as an adjunct modality in nursing practice and the management of CKD symptoms.   Keywords: Chronic Kidney Disease; Complementary Therapy; Hemodialysis; Uremic Pruritus.   Pendahuluan: Uremic pruritus merupakan kondisi inflamasi kulit yang sering menjadi masalah pada pasien dengan chronic kidney disease (CKD) terutama yang menjalani hemodialisis Tujuan: Untuk mengetahui efektivitas terapi komplementer topikal alami dalam menurunkan uremic pruritus. Metode: Penelitian literature review menggunakan metode Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Desain pencarian artikel dengan merumuskan PICOS yaitu P (problem, patient, or population), I (intervention, prognostic factor, or exposure), C (comparison or control), O (outcome) dan S (study). Pencarian literatur yang digunakan berasal dari clinicalkey, clinicalkey for nursing, Proquest, Sciencedirect, Scopus, Ebscohost, Taylor & francis dan Wiley kemudian diekstraksi mendapatkan 8 artikel yang relevan dan dapat digunakan. Hasil: Sebanyak 8 artikel yang memenuhi kriteria inklusi. Terdapat 9 jenis bahan alami yang diidentifikasi: violet oil, cannabis, Ziziphus jujube, Anethum graveolens (dill), sesame oil, Avena sativa, ostrich oil, dan almond oil. Intervensi ini dilakukan dengan dan tanpa manipulasi. Studi menunjukkan penurunan intensitas pruritus yang signifikan (p<0.05) dengan metode pemberian terbanyak berupa aplikasi topikal 2 kali sehari selama 2-4 minggu. Efek tambahan lainnya seperti perbaikan kulit kering, kualitas tidur, dan kualitas hidup juga dilaporkan. Tidak ada efek samping signifikan yang ditemukan. Simpulan: Terapi komplementer topikal alami efektif, aman, dan dapat diterima dalam menurunkan uremic pruritus pada pasien CKD dan yang menjalani hemodialisis. Ekstrak berbasis tumbuhan lebih direkomendasikan karena kemudahan ekstraksi dan penerimaan pasien. Terapi ini dapat dijadikan modalitas tambahan dalam praktik keperawatan dan manajemen gejala CKD.   Kata Kunci: Gagal Ginjal Kronis; Hemodialisis; Pruritus Uremik; Terapi Komplementer.
Co-Authors Agung Waluyo Amelia Kurniati Aminah Soemadi Al Djuwardi Ardiyati, Adelina Vidya Debbie Dahlia Debie Dahlia Dewi Ayu Pratiwi Dwi Cahya Rahmadiyah Efadatus Zakiyah Elly Nurachmah Estefania Dos Santos Etty Rekawati Eva Yulianti Fathiya Hanisya Fina Mahardini Gipta Galih Widodo Hanisya, Fathiya I Made Kariasa I Putu Adi Suryawan I Putu Adi Suryawan Imelda Imelda Indira Mastura Pulungan Jesica Pasaribu Laode Saltar Maria Fulgensia Bengu Ndona Nekka Juliani Neng Intan Ni Wayan Astiti Pertiwi Novrin Senselia Putri Ziliwu Nurul Aini Sabichiyyah Nurul Azizatunnisa Pius Almindu Leki Berek Priyanto Priyanto Rachmawati, Utami Rahmadiya, Siska Retno Yuli Hastuti Ria Andriani Rima Novia Putri Rinda Apriani Riri Maria Riri Maria Rizky Hidayat Siska Rahmadiya Sri Hariyanti Sri Yona Susanti Niman Tuti Herawati Umi Solekhah Umi Solekhah Utari Christya Wardhani Vetty Priscilla Wahyuni, Anyta Hera Yeane Anastania Yulia Yulia Yunizar Gultom