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All Journal VALENSI GRADIEN Jurnal Ilmu Kefarmasian Indonesia Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Pharmacopoeia Bencoolen Journal of Pharmacy Rafflesia Journal of Natural and Applied Sciences (RJNAS) Jurnal Sains & Kesehatan Darussalam
Dwita Oktiarni
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Assessment of Macronutrient Dynamics in a Tropical Watershed: A Study from Bengkulu River and Estuary Indonesia Wiwit, Wiwit; Ikhsani, Idha Yulia; Nurhamidah, Nurhamidah; Oktiarni, Dwita; Wong, Kuo Hong
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 1, May 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i1.42477

Abstract

This study assesses the sources, transport, and distribution of macronutrients, including nitrate, nitrite, silicate, and phosphate, starting from the upper stream of the Bengkulu River, which is the biggest river in Bengkulu Province, to the coastal seawater of the eastern tropical Indian Ocean. The sampling was conducted using an acid-washed polypropylene beaker and placed in acid-cleaned 5 L polyethylene containers during the dry season in July 2024. The water samples were collected from the surface waters of 15 stations. The macronutrients in the water samples were determined using a spectrophotometer UV-Vis following the Strickland and Parsons method. Macronutrient analysis was conducted in LATERIO BRIN, Jakarta, Indonesia. The concentration of analysed macronutrients ranged from 0.005 - 0.058 mgN-NO3/L for nitrate, <0.001 - 0.014 mgN-NO2/L for nitrite, 0.163 - 9.314 mgSi-Si(OH)4/L for silicate, and 0.01 - 0.085 mgP-PO4-/L for phosphate. Several stations, including Stations 6, 10, and 14, exhibited relatively elevated nitrate concentrations, which were further supported by similarly high phosphate levels. Stations 6, 10, and 14, situated near areas of intense anthropogenic activity in Bengkulu City, suggest that human-induced inputs have enriched the water environment with macronutrients. The highest silicate concentration was observed at Station 1, located upstream in the Bengkulu River. This aligns with previous findings and underscores the role of weathering processes in controlling silicate distribution. Compared to the macronutrient concentration guidelines for river water set by Indonesian Government Regulation 2021 No. 22, the nitrite concentrations at certain river stations exceeded the safety threshold for aquatic biota. In contrast, nitrate and phosphate levels remained within the safe range.
Aktivitas Antibakteri Secara In-Vitro Ekstrak Metanol Excoecaria cochinchinensis Lour dan Kombinasinya dengan Obat Komersial Nurhasana, Devi; Febriansyah, Rahmaga; Avidlyandi, Avidlyandi; S., Salprima Yudha; Banon, Charles; Oktiarni, Dwita; Adfa, Morina
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1383

Abstract

The purpose of this study was to look into the antibacterial activity of methanolic extract of Excoecaria cochinchinensis as well as the effect of its combination with antibiotics on the growth of Klebsiella pneumoniae, Enterobacter aerogenes, and Staphylococcus epidermidis. The antibacterial activity test was carried out using the well diffusion method, and the combined effect of the extract and antibiotics was observed using the paper strip diffusion method. At various concentrations (25, 50, 75, 100, 150, 200, and 250 mg/mL), the extract significantly inhibited the growth of K. pneumoniae, E. aerogenes, and S. epidermidis. The inhibitory zone's diameter increased proportionally with the extract concentration. The growth of K. pneumoniae and S. epidermidis was then classified as extremely sensitive (+++) to the addition of the extract at 200 and 250 mg/mL concentrations, meanwhile, E. aerogenes’s with 250 mg/mL of the extract. Secondary metabolites such as oleanolic acid, arjunolic acid, scopoletin, kaempferol, quercetin, diterpenoid compounds, tannins, and other phenolics have been reported from E. cochinchinensis leaves and are thought to be responsible for its antimicrobial activity. The effect of the extract’s combination with antibiotics was insignificant compared to their individual activity, thereby classifying them as indifferent.
Co-Authors A.A. Ketut Agung Cahyawan W Agus Martono Agus Martono Hadi Putranto Avidlyandi, Avidlyandi Charles Banon Deni Agus Triawan Dominica, Dwi Dyah Fitriani Eka Angasa Febriansyah, Rahmaga Firza, Bunga Al Gaol, Amelia Debora Lumban Harianti Putri, Yona Idha Yulia Ikhsani, Idha Yulia Irfan Gustian Lusiana Lusiana Morina Adfa Nabila Zhavira Nesbah Nesbah Nesbah, Nesbah Nurhamidah Nurhamidah Nurhasana, Devi Oktoviani Oktoviani Putri, Yona Harianti Rahmawati, Reza Sal Prima Yudha S SALPRIMA YUDHA S Suripno Suripno Syalfinaf Manaf Virania, Geatika Wiwit, Wiwit Wong, Kuo Hong Yona Harianti Putri