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All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal VOK@SINDO Jurnal NERS MNJ (Malang Neurology Journal) Health Notions Journal Orthopaedi and Traumatology Surabaya (JOINTS) SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Journal of Social Research Journal of Pain, Vertigo and Headache Folia Medica Indonesiana
Imam Subadi
Department Of Physical And Rehabilitative Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya/ Dr. Soetomo General Academic Hospital, Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Jurnal VOK@SINDO

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Expression of Β-Endorphin In Relieving Inflammation Pain after Dry Cupping Therapy Imam Subadi
Jurnal VOK@SINDO Vol 2, No 2 (2014)
Publisher : Program Pendidikan Vokasi Universitas Brawijaya

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Abstract

Pain is a chief complaint most frequently seen in daily practice. Dry cupping therapy has been used for pain management but the mechanism of action is unclear. Beta endorphin is an endogenous morphin that can relief pain.The objective of this study is to show the relationship betweenβ-endorphin expression and pain relief in dry cupping.This experimental study employed randomized control group post test design. Twenty four Wistar rats (Rattus norvegicus) were assigned to three groups of 8 subjects, which were normal rats (control negative), group undergoing Complete Freund’s Adjuvant (CFA) only (control positive group) and group undergoing CFA and dry cupping (negative pressure: - 200 mmHg, 5 minutes). Samples were retrieved from skin and performed immunohistochemical of monoclonal anti β-endorphin. Pain threshold reaction time was measured by hot-plate. Data were then statistically analysed by Independent-Sample t Test, Linear Regresion analysis using SPSS version 17.This study found out that expression of β-endorphin, p= 0.000 and pain threshold reaction time on dry cupping, p= 0.001 had increased compared with the control group. There was relation between increased β-endorphin with pain threshold reaction time in dry cupping (β= 0.542; p= 0.030). In other words, dry cupping can decrease pain caused by the expression of β-endorphin
Co-Authors Afifur Rafi Hilmi Aziz Ahmad Arif Ridha Ana Mursyida Andre Triade Desnantyo Andriana, RA Meisy Andriati Andriati Andriati Andriati Benni Azhari Damayanti Tinduh Dewi Septiani M K Sintia Diah Indriani Fauza Alfin Fidiana Fiequria Asri Ersyana Ganing, Sirly Nabireta Maharani Hanik Hidayati HARJANTO HARJANTO Harjanto JM Harjanto JM Hening Laswati Putra Islam, Mohamad Saiful J. A. Pangkahila Jeremy Nicolas Sibarani Kusumawardhany Airlangga Rijanti Langgeng Gunariadi Lydia Arfianti Mangestuti Agil Martino, Nieko Caesar Agung Masduchi, Reni Hendrarati Mulyana, Darian Nugraheni S. Nuniek Nuniek Nugraheni Nur Sulastri Nur Sulastri Patricia Maria Kurniawati Paulus Sugianto, Paulus Pawana, I Putu Alit Poerwandari, Dewi Putri, Nila Novia Raden Argarini Rejeki, Purwo Sri Retno Widyowati Rijanti, Kusumawardhany Airlangga Rwahita Satyawati Dharmanta Semedi, Bambang Pujo Sirly Nabireta Maharani Ganing, Sirly Nabireta Soenarnatalina Melaniani Soenarnatalina Melaniani Sony Wibisono Subagyo Subagyo Tedy Apriawan Turchan, Agus Utama Hutapea, Johannes Diandra Indra Vanydia Aisyah Wardhani, Indrayuni Lukitra Wigati, Kristanti Wanito Yuanita, Ida Yuli Indah Kurnia Yuliasih Yuliasih