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All Journal Natural Science: Journal of Science and Technology Jurnal Bios Logos Warta Rimba Biocelebes Journal of Health and Nutrition Research Mitra Sains
Ramadanil Pitopang
Jurusan Biologi, Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Tadulako
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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POLA DISTRIBUSI DAN KERAPATAN ROTAN (Daemonorops robusta Warburg) DI HUTAN PEGUNUNGAN SEKITAR NOKILALAKI KECAMATAN PALOLO KABUPATEN SIGI SULAWESI TENGAH Ramadanil; Grisnayanti
Biocelebes Vol. 15 No. 1 (2021)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v15i1.15557

Abstract

Penelitian tentang ’’Pola Distribusi dan Kerapatan Rotan (Daemonorops robusta Warburg) di Hutan Pegunungan Sekitar Nokilalaki Kecamatan Palolo Kabupaten Sigi Sulawesi Tengah’’ telah dilakasanakan dari bulan Desember 2018 sampai Februari 2019. Penelitian ini menggunakan metode survey eksploratif dengan menjelajah kawasan pegunungan Nokilalaki, untuk mencari populasi D. robusta Warburg. Proses pengambilan sampel menggunakan metode garis transek yang berukuran 50 x 10 m dengan penempatan transek secara purposive sampling sebanyak 7 buah. Hasil pengamatan menunjukan bahwa hasil Indeks Morisita pada D. robusta Warburg yaitu mengelompok dan nilai kerapatan relatif tertinggi pada tingkat anakan terdapat pada transek I yaitu 32,4%,terendah pada transek III yaitu 8,1% dan nilai kerapatan relatif tertinggi pada tingkat dewasa terdapat pada transek I 38,4% dan terendah pada transek II dan VI yaitu 11,5%.
PEMANFAATAN TUMBUHAN SEBAGAI OBAT TRADISIONAL OLEH ETNIS TO BALAESANG DI DESA RANO, KABUPATEN DONGGALA, SULAWESI TENGAH: Traditional Usage of Plant as Medicine by “To Balaesang” Ethnic In the Donggala District, Central Sulawesi Ramadanil Pitopang; Dandy Prayoga; PUTI ANDALUSIA BANILAI; Moh Iqbal
Biocelebes Vol. 16 No. 1 (2022)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v16i1.15878

Abstract

This paper discusses the result of the study on "traditional plant use as medicine by the Balaesang tribal community in Rano village, Balaesang, Donggala district, Central Sulawesi", Indonesia. The research was conducted from December 2020 to March 2021. The basic data of traditional plant used by local ethnic were collected through an in-depth interview initiated by an informed consent using a questionnaire containing open-ended questions. A snowball technique was used to obtain appropriate respondents including the village leader and traditional healers. The results showed that there were 42 plants species (consist of 26 families) that are used as traditional medicine by the Balaesang tribe. Some of plants were utilized for beauty purpose, chronic diseases, skin, hypertension, gastrovascular and other diseases. The preparation method is boiled, ground, consumed directly, squeezed, smeared, and chewed
FITOKIMIA, DAN AKTIFITAS ANTIBAKTERI DARI Etlingera sublimata Poulsen (ZINGIBERACEAE), TUMBUHAN ENDEMIK SULAWESI: Phytochemical and Antibacterial Activity of Etlingera sublimata Poulsen (Zingiberaceae), Endemic Plant to Sulawesi Ramadanil Pitopang; Endang Lestari; PUTI ANDALUSIA SARIGANDO Banilai; Wahyu Harso
Biocelebes Vol. 16 No. 2 (2022)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v16i2.15957

Abstract

The research entitled "Phytochemical Screening and antibacterial activity of Etlingera sublimata Poulsen (Zingiberaceae), an Endemic Sulawesi of Plants was conducted from January 2020 to June 2020, at the Plant Biosystematics Laboratory and Biotechnology Laboratory, Department of Biology, Faculty of Mathematics and Natural Sciences, Tadulako University. Samples of E. sublimata were collected from the mountane forests of the Lore Lindu National Park (LLNP), arround Sedoa village, Lore Utara District, Poso Regency The objectives of the research were to analyze the secondary metabolite compounds in E. sublimata plants and to determine the antibacterial activity of E. sublimata leaves extract in againts Salmonella thypii bacteria. Plant samples were extracted by maceration methods with 96% ethanol as a solvent. Actibacterial activity was tested by using agar well diffusion methods. The experiment was designed by Completely Randomized Design (CRD) with seven different concentration of E. sublimata extract (15, 25, 50, 75 and 85%). Extract and standard drugs were prepared in double-distilated water using Nutrient Agar tubes. 2% Chloramphenicol as standard drugs was used as a positive control and sterile aquadest was used as a negative control. The inhibition zone of bacteria and yeast growth around the disk was measured after 18 to 24 h incubation at 37°C. The results showed that the stem contains alkaloids, flavonoids, terpenoids, tannins and saponins. The rhizome containts alkaloid, flavonoids, terpenoids, tannins and saponins, the flowers containts alkaloid, terpenoids and tannins, while the leaves containts tannin and saponin compounds. Leaves extract of E.sublimata has inhibition activity on the cell growth a pathogenic Salmonella thypi bacteria that the effective extract concentration was 50% with an average inhibition zone ​​2.67 mm.
An Ethnomedicinal study of Medicinal Plants Used against Gastrointestinal Complaints By “Kaili Ledo Ethnic” in Central Sulawesi, Indonesia Mohammad Yant Pratama; Yusran Yusran; Ramadanil Pitopang
Mitra Sains Vol 9 No 1 (2021): Maret
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/ms26866579.2021.v9.i1.pp26-33

Abstract

The research entitled “An ethnomedicinal study of medicinal plants used against gastrointestinal complaints by Kaili Ledo Ethnic in central Sulawesi, Indonesia was undertaken from May 2019 to March 2020. The research site was located in Raranggonau, an oldest subvillage of Kailinese Ledo aimed to conserve the ethnomedicinal knowledge of Kaili Ledo ethnic in using plants for healing gastrointestinal complaints and to select candidate medicinal plants for further phytochemical and pharmacological investigation. The data indigenous knowledge of medicinal plant has been collected by using in-depth interview with prior informed consent using an open-ended questionaire. A snowball technique was performed to obtain a appropriate respondents. Descriptive statistical method was employed to analyse and summarize the ethnobotanical data on the reported medicinal plants and associated knowledge. The result showed that there were 25 plants belonging to 16 families were found to be used against gastrointestinal complaints in the studied area. Most dominant family used against gastrointestinal complaints was Lamiaceae (3 plants), followed by Poaceae, Fabaceae, Euphorbiaceae and Asteraceae (2 plants each). Solanaceae, Asparaginaceae, Araucariaceae, Rosaceae, Rubiaceae, Musaceae, Melastomataceae, Caricaceae, Basellaceae and Balsaminaceae (1 plant each).
POPULASI & POLA DISTRIBUSI Buchanania arborescens (Blume) Blume (Anacardiaceae) PADA TANAH ULTRA- MAFIK DESA PODI, KECAMATAN TOJO, KABUPATEN TOJO UNA-UNA, SULAWESI TENGAH Pitopang, Ramadanil; Syam, Nurfadilah; Rasyiid, Mustafid
Biocelebes Vol. 18 No. 1 (2024)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v18i1.17197

Abstract

This study aims to determine the distribution pattern and population density of Buchanania arborescens (Blume) Blume in Ultramafic Soil, Podi Village, Tojo District, Tojo Una-Una District, Central Sulawesi. Observations were made using the purposive sampling method by establishing five (5) transects 50x10 m in size which there were subplots with size 10x10 m to observe tree (DBH >10 cm), 5x5 m for the sapling and 2x2 m for seedling with a distance of 20 m between transects. The distribution pattern of Buchanania arborescens at the study site was determined by calculating the morbidity index with the results of calculations on seedling phase Id (0.04), sapling Id (0.05) and tree Id (-1.00). The highest density of Buchanania arborescens is in the seedling phase with a value of 200 individuals/Ha, the sapling phase is 176 individuals/Ha and the lowest value is in the tree phase with a total density of 40 individuals/Ha. The results showed that the distribution pattern of Buchanania arborescens for the seedling and sapling phases were clumped, while the tree phase was uniform. The density of Buchanania arborescens was rare density category.
The Anticancer Activity of Ethanol Extract of Begonia medicinalis on Colorectal Cancer Rat Model Induced With 7,12-Dimethylbenz[A]Anthracene Guli, Musjaya; Ardiputra, Muh Akbar; Pitopang, Ramadanil; Sari, Retno; Hatta, Mochammad; Prawiro, Sumarno Reto; Saifah, Andi; Sardi, Bambang; Rahma, Rahma; Rahmawati, Nurul Dina
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.411

Abstract

Colorectal cancer remains one of the leading causes of cancer-related deaths after lung cancer, highlighting the urgent need for more effective therapies with minimal side effects. Begonia medicinalis has been reported to have potential anticancer properties. This study aimed to evaluate the anticancer activity of Begonia medicinalis extract by assessing neutrophil concentration in a 7,12-dimethylbenz[a]anthracene (DMBA)-induced colorectal cancer rat model. The research employed a laboratory-based experimental approach with a post-test-only group design, comprising five groups with five replications each: treatment group I receiving a 25 mg/kg body weight, treatment group II receiving a 50 mg/kg body weight, treatment group III receiving a 100 mg/kg body weight, an normal group that was not DMBA-induced and did not receive therapy, and a negative control group that was DMBA-induced but did not receive therapy. The results of this study demonstrate that Begonia medicinalis extract effectively suppresses neutrophil concentration in a DMBA-induced colorectal cancer rat model. Treatment with 50 mg/kg body weight and 100 mg/kg body weight doses successfully reduced neutrophil cell levels in the experimental subjects, with the best results seen at the 100 mg/kg body weight dosage. This study provides new insights into the effects of plant-based therapies, Begonia medicinalis extract, in modulating the immune system by suppressing neutrophil concentration in a colorectal cancer rat model.
Co-Authors Achmad Ramli Adhil, Adhil Alvionita Alvionita Andi Saifah Andi Wirdani Pettalolo Annawaty Annawaty, Annawaty Ardiputra, Muh Akbar Bambang Sardi Bratawinata, Ariffien Dandy Prayoga Eka Putri Dayanti Endang Lestari Eny Yuniati Erwin Taslim Evanjeli Evanjeli Fat Hulia Fitriani Dg. Kalla Grisnayanti Guli, Musjaya Hijrah Hijrah I Nengah Suwastika Iis Salihat Inayanti, Fanny Is Patuh Hallianah Kambuno, Iring R. F. Kurniawan P. Bandjolu M Saleh, M Fajri Ramadan Mochammad Hatta Moh Iqbal Moh Iqbal Moh. Iqbal, Moh. Mohammad Ihsan Mohammad Yant Pratama Mustafid Rasyiid Naharuddin Naharuddin Neneng Sukmawati Nunung Safriana Nur Afiyah Labambe Orryani Lambui Paserang, Asri P. Prawiro, Sumarno Reto PUTI ANDALUSIA BANILAI PUTI ANDALUSIA SARIGANDO Banilai Rahma Rahma Rahmawati, Nurul Dina Rahmita, Rahmita Ramawangsa, Panji Retno Sari Risma Risma Rizaldi, Reza Roland P P Ahmad Rusmin Rusmin Samsurizal, M. Sulaeman Sari, Riska Satria Dhika Saputra Sigit Hardwinarto, Sigit Stevani Tamawiwi Syam, Nurfadilah Wahyu Harso Yayang Istikana Yusran Yusran Zubair Zubair