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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Masyarakat Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Journal of Health Education Padjadjaran Journal of Dentistry Jurnal Manajemen Informasi dan Administrasi Kesehatan Jurnal Formil (Forum Ilmiah) Kesmas Respati Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal
Dibyo Pramono
Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Polypharmacy and oral health-related quality of life in older adults: a systematic review Lelyana, Shelly; Agustina, Dewi; Hendrartini, Julita; Pramono, Dibyo
Padjadjaran Journal of Dentistry Vol 37, No 1 (2025): March 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no1.58618

Abstract

Introduction:: Patient-centered care requires medical personnel to address not only physical illnesses but also the psychosocial well-being of patients. older adultsOlder adults often have medically complex conditions, including one or more chronic diseases, requiring the use of multiple medications (polypharmacy). Polypharmacy is a common problem among older adults, with a reported prevalence of 30% to 80%. Many prescribed medications can lead to xerostomia and hyposalivation, which negatively impact the quality of life , including Oral Health-Related Quality of Life (OHRQoL). This systematic review aims to determine the impact of polypharmacy on OHRQoL in older adults and explore strategies to optimize OHRQoL in this population. Method: The dataset of articles concerning polypharmacy and OHRQoL in older adults was compiled from Google Scholar, PubMed, Semantic, and OpenAlex. The search encompassed publication from 2019 to 2024. Five articles were selected for in-depth analyses, and variations in methodologies used by the researchers in these selected studies were identified and considered. Results: Patients with polypharmacy hyposalivation exhibited significantly higher scores of the Summated Xerostomia Inventory questionnaire (SXI-PL) (8.60 ± 2.56) and the Oral Health Impact Profile-14 (OHIP-14sp) (16.0 ± 15.8). A statistically significant association was found between hyposalivation and both SXI-PL and OHIP-14sp scores (p < 0.05). Elderly individuals on continuous medication demonstrated increased odds of self-reported xerostomia (OR: 2.3; 95% CI: 1.19-4.67; P = 0.009). Conclusion: This study demonstrates an association between polypharmacy and decreased oral health-related quality of life (OHRQoL) in older adults.
Epidemiologic profile of oral squamous cell carcinoma in Yogyakarta, Indonesia Gracia, Isadora; Utoro, Totok; S., Supriatno; Astuti, Indwiani; Heriyanto, Didik Setyo; Pramono, Dibyo
Padjadjaran Journal of Dentistry Vol 29, No 1 (2017): March 2017
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.633 KB) | DOI: 10.24198/pjd.vol29no1.11614

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ABSTRACTIntroduction: Oral cancer is a major health problem in the world, indicated by a high incidence of recurrence. In Southeast Asia, oral cancer ranks sixth from all cancers on the human body. The incidence of oral cancer, especially squamous cell carcinoma types, increases every year, but the prognosis and patients life expectancy are still unsatisfying enough and the reports about the profile of oral cancer is still limited.The objective of this research was to get the epidemiological profile of oral squamous cell carcinoma (OSCC) in Yogyakarta, Indonesia. Methods: The research method was observational analytic with cross-sectional design. All new OSCC cases in three anatomic pathology laboratory installations in Yogyakarta (January 2011-December 2015) were included in this study. Data collected were gender, age, anatomical location, and histology. All data were analyzed using statistical analysis program. Results: OSCC new cases amount increasing each year: 6 cases (6.6%) in 2011, and increased to 24 cases (26.4%) in 2015. Fifty-two of the 91 cases (57.1%) were found on male. The age group with the most cases was found in group of 41-60 years (49.5%). There is no difference in the case distribution by age between male and female. Forty-eight cases were found in the lingual part (52.7%). Histological examination showed 68 cases (74.7%) were well-differentiated carcinoma. Conclusion: OSCC profile in Yogyakarta mostly found in men with anatomical location in the lingual part in the age group above 40 years of age and were having well-differentiated histology.Keywords: Oral squamous cell carcinoma (OSCC), Epidemiologic profile, Yogyakarta 
EVALUASI PROGRAM EARLY WARNING ALERT AND RESPON SYSTEM (EWARS) DALAM PELAKSANAAN SURVEILANS KLB KOTA SALATIGA PROVINSI JAWA TENGAH Wikansari, Nurvita Wikansari; Santoso, Dian Budi; Pramono, Dibyo; Widarsih, Dyah W
Jurnal Manajemen Informasi dan Administrasi Kesehatan Vol. 2 No. 1 (2019): JMIAK
Publisher : Program Studi D3 Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32585/jmiak.v2i01.449

Abstract

Outbreaks of disease can result in a large increase in morbidity and mortality, have an impact on tourism, economics and social, so there is a need for an Extraordinary Early Response and Response System (EWARS) (Early Warning and Response System). SKDR has been socialized and replicated gradually throughout Indonesia. Salatiga is one of the cities in Central Java Province and has 6 health centers that have been running the EWARS program in early detection of outbreaks but still occur every year. It is necessary to evaluate the EWARS Program at the Salatiga City Health Service.Evaluation was carried out with a descriptive study of analysis, namely evaluating aspects of input, process, output and outcome by interviewing questionnaires to EWARS health center program administrators and Salatiga City Health Service.The problem with input is that officers have multiple tasks ?2 (67%) and there are no adequate funds. In the process of targeting and planning (50%) and coordination across sectors (33%). At the output, the officer did not send the report on time and in the outcome of the detection of outbreaks as early as possible but there was no epidemiological bulletin to inform public health every week.There are a number of things that need to be addressed in the EWARS program in Salatiga, namely human resources, facilities and infrastructure as well as planning and implementation. There needs to be equal employment, EWARS training for puskesmas officers and municipal health offices so that they can detect and analyze potentially outbreak diseases as early as possible.
Effect of diabetes mellitus as a modifier with periodontitis severity and oral health–related quality of life in older adults: a cross-sectional study Utami, Sri; Kusnanto, Hari; Pramono, Dibyo; Ratna Astuti, Novitasari Ratna; Hasnasari Heningtyas, Afina; Oktavia, Nova; Afrilyana Ulzanah, Fannisa
Padjadjaran Journal of Dentistry Vol 38, No 1 (2026): March 2026
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol38no1.67700

Abstract

Introduction: The main complication of diabetes mellitus (DM) in the oral cavity is periodontitis. Periodontitis is one of the conditions that affects quality of life because it causes psychological discomfort, stress, interpersonal relationship problems, and difficulties in daily activities. The objective of this study was to analyze the effect of diabetes mellitus as a modifier with periodontitis severity and oral health–related quality of life in older adults. Methods: This study is a cross-sectional study, where this design can be used to provide the groundwork to infer preliminary evidence for a causal relationship. The subjects were 302 elderly individuals aged ≥ 60 years who still had at least 6 teeth representing 6 regions. The study variables were the severity of periodontitis, Oral Health-Related Quality of Life (OHRQoL), and diabetes mellitus (DM). Periodontitis was diagnosed using the classification from the American Association of Periodontology (AAP) and the European Federation of Periodontology (EFP) in 2018, using the Clinical Attachment Loss (CAL) indicator. The Geriatric Oral Health Assessment Index (GOHAI) was used to measure OHRQoL. DM status was diagnosed using HbA1c levels. Data analysis was performed using multiple linear regression with a significance level of 0.05. Results: The majority of participants had severe periodontitis (73.8%) followed by moderate periodontitis (22.2%) and mild periodontitis (4%). The results of multiple linear regression analysis showed that there was an interaction between uncontrolled DM and periodontitis on OHRQoL (Adj.β = -11, p=0.05). Conclusions: Diabetes mellitus acts as a modifier effect on the relationship between the severity of periodontitis and OHRQoL. The more severe the periodontitis, the lower the OHRQoL. Uncontrolled DM influences the direct relationship between periodontitis severity and OHRQoL. The relationship between periodontitis severity and OHRQoL is stronger and more pronounced in uncontrolled DM
Co-Authors A.A. Ketut Agung Cahyawan W Adi Utarini Afrilyana Ulzanah, Fannisa Ahmad Hamim Sadewa Alfasunu, Serafim Dede Kurniawan Dewi Agustina Dewi Ratnawati dharmawijaya, isa Didik Setyo Heriyanto Firdaus Hafidz As Shidieq Hanafi, Arif Riswahyudi Hari Kusnanto Hasnasari Heningtyas, Afina Imelda, Priscillia Indwiani Astuti Isadora Gracia, Isadora Jayusman, Achmad Mulawarman Julita Hendrartini Junaedi Junaedi Khabib Mualim, Khabib Khasanah, Faridatun Laelia Dwi Anggraini, Laelia Lelyana, Shelly Ning Rintiswati Oktavia, Nova Pratiwi, Rita Dian Pratiwi, Rita Dian Prihastuti, Rieski Ratna Astuti, Novitasari Ratna Rinaldi Budi Utomo Riris Andono Ahmad Sa'adah, Nur Raudatus Santoso, Dian Budi Siti Boedina Kresno Sofia Mubarika Haryana Sri Sahayati Sri Utami Sunarno, Sunarno Supriatno Totok Utoro Widarsih, Dyah W Wikansari, Nurvita Wikansari yuningrum, hesti