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All Journal Majalah Kedokteran Bandung Damianus Journal of Medicine Sari Pediatri Paediatrica Indonesiana Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Urban Health Research
Edward Surjono, Edward
School Of Medicine And Health Sciences Atma Jaya Catholics University Of Indonesia
Health Professions Medicine & Pharmacology Public Health

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Antioxidant, Antimicrobial, Anti-Inflammatory, and Gut Microbiota Modulation Effects of Kombucha: a Literature Review Hananta, Linawati; Kurniawan, Sandy Vitria; Lonah; Arieselia, Zita; Surjono, Edward; Setiawan, Jonny; Lieputra, Andrew Adhytia; Puspa Bunardi, Dewi; Prayoga Tjendratama, Jason; Vallerie Satyadi, Richelle; Dewi, Rita
Journal of Urban Health Research Vol. 3 No. 2 (2025): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v3i2.6445

Abstract

Introduction: The interest in probiotics has increased significantly in recent years. While most probiotic-containing foods are dairy-based, an increasing number of non-dairy probiotic products have emerged, including kombucha. Kombucha is a fermented tea beverage originating from China, known for its high polyphenol content and potential health benefits. Methods: This literature review aims to provide a comprehensive understanding of the health benefits of kombucha. A systematic search of published studies was conducted using the keywords "kombucha," "antioxidant," "anti-inflammatory," "antimicrobial," and "gut microbiota modulation." Only English-language articles were included, and there was no restriction on publication date to capture the full spectrum of research on kombucha. Results: Kombucha exhibits significant antioxidant capacity, with green tea kombucha demonstrating the highest Ferric Ion Reducing Antioxidant Power (FRAP) due to its high polyphenol content. Additionally, kombucha possesses antimicrobial properties attributed to organic acids, lactones, aldehydes, fatty acids, and alkaloids, which act synergistically. It also exhibits anti-inflammatory effects by inhibiting nitric oxide production and downregulating pro-inflammatory cytokines such as IL-1β and TNF-α. Furthermore, kombucha modulates gut microbiota composition by inhibiting the growth of Gram-negative bacteria, leading to reduced systemic inflammation and oxidative stress. Conclusion: Kombucha, a traditional fermented tea, has notable health benefits, including antioxidant, antimicrobial, anti-inflammatory, and gut microbiota-modulating properties. These findings highlight its potential as a functional beverage for health promotion. Keywords: kombucha – antioxidant - anti-inflammatory – antimicrobial - gut microbiota modulation
Tummy Time and Development of 6- to 12-Month-Old Infants Titah, Marvella Graceria; Surjono, Edward; Prabowo, Johanes A. C.; Setiawan, Andy; Dewi, Rita
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.3928

Abstract

Early childhood development, particularly within the first 1,000 days of life, is a critical period. Globally, 5–16% of children experience developmental delays. This figure is higher in Indonesia with approximately 13–18% of children under five are facing growth and developmental issues. Adequate stimulation, including activities like tummy time, plays a vital role in a child's growth and development. This study aimed to investigate the correlation between tummy time and the developmental outcomes of infants aged 6–12 months. An analytical descriptive design with a cross-sectional approach was employed in this study that was conducted at Public Health Centers in North Sulawesi Province, Indonesia. Data collection involved questionnaires assessing the onset, frequency, and duration of tummy time, alongside the use of the Child Development Pre-Screening Questionnaire. With a minimum sample size of 96 respondents, data were analyzed using Spearman’s correlation. Findings indicated that performing tummy time more than 1–2 times per week, with each session lasting 6–20 minutes, was significantly associated with better developmental outcomes. However, no significant relationship was observed between early initiation of tummy time or the number of daily sessions with infant development. The study concluded that engaging in tummy time more than 1-2 times per week for 6-20 minutes per session can promote optimal infant development.
Co-Authors Agus Firmansyah Andy Setiawan Andy Setiawan Andy Setiawan Budiyanti, Ecie Clifford Peter Anthony Divara Ariesta Sekar Suryadi, Made Edihan Mardjuki Ellen Wijaya Ellen Wijaya Elvira, Junita Evi Ulina Margaretha Situmorang Fan, Tan Fei Gita S. Candijaya Hadiyanto Hadiyanto Jeceline Sutarto Jonny Setiawan Jose RL Batubara Kevin Gunawan Kurniawan, Sandy Vitria Lieputra, Andrew Adhytia Linawati Hananta, Linawati Lonah, Lonah Mariani Santosa, Mariani Nabila Arfimita Prabowo, Johanes A. C. Prayoga Tjendratama, Jason Puspa Bunardi, Dewi Rachel Roselany Rita Dewi Titah, Marvella Graceria Vallerie Satyadi, Richelle Vicky Sagita Hanka Vivian Angelina Harsono Yuliana Yuliana Zita Arieselia