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Study Direction to Oxidize a Local Pine Rosin with Potassium Permanganate Widia Edy Kuncoro; Moh. Farid Rahman; Masruri MASRURI, Ph.D; Siti Mariyah Ulfa
The Journal of Pure and Applied Chemistry Research Vol 12, No 1 (2023): Edition January-April 2023
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpacr.2023.012.01.3298

Abstract

Pine rosin acid or Gondorukem is a solid resin obtained from pine sap. It is yielded as residue from a high temperature distillation process. In industry, rosin acid is widely used and modified as raw material in paint, ink, adhesive, resin, thermoplastic, and thermosetting polymer. Modification process generally is undergone to generate rosin acid with specific properties and for certain purposes. This paper report, potassium permanganate oxidation reaction of pine rosin acid under acidic process at low temperature. Product identified as 13,14-seco-13-oxoabiet-7-ene-dioic acid (0.52%), 7,8-dihydroxy-abietic acid (6.62%), and 7-oxo-dehydroabietic acid (1.49%). The crude product was isolated as a pale to white solid. Under high temperature a yellowish product was resulted. In overall, the yield isolated in between 46.4% and 86.0%.
Screening of Aroma Compounds in Commercial Tea (Camellia sinensis) from Indonesia and Testing Their Activity as Antioxidants Warsito, Warsito; Alief, M. Fadel; Azzahra, Vina Octavia; Rahman, M. Farid; Retnowati, Rurini
Journal of Tropical Pharmacy and Chemistry Vol. 8 No. 2 (2024): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

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Abstract

Tea from tea leaves of the Camellia sinensis species is a superior industrial plant that promises superior bioactivity. For a more in-depth study of the essential oils contained in commercial teas on the market, their significant characteristic from their constituent compounds were determined. The essential oil yields of the three commercial samples were obtained by distillation using a Liken-Nickerson vessel and analyzed by gas chromatography-mass spectrometry (GC-MS), then tested for antioxidant properties by the DPPH method. The yield obtained ranged from 0.08-0.13%. The main major components (more than 0.5% identified) contained in the three samples identified were benzyl acetate, between 4,56-26.27%, and linalool compounds from tea leaves, as much as 20.59%, and 3.42% in samples C and B which were not found in sample A. As shown by our results, antioxidant activity significantly correlated with benzyl acetate and linalool composition. Sample A showed the best antioxidant profile, with highest inhibition (IC50 20.19 mg/mL).
Preparation of Carrageenan/Chitosan/Curcumin Hydrogel Films: Physicochemical Characterization and In Vitro Evaluation as a Promising Diabetic Wound Dressing Sry Agustina; Saidun Fiddaroini; Ahmad Luthfi Fahmi; Ruslan; Elvina Dhiaul Iftitah; Moh. Farid Rahman; Akhmad Sabarudin
Science and Technology Indonesia Vol. 11 No. 3 (2026): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2026.11.3.994-1015

Abstract

Wound dressings with their physical characteristics that can maintain moisture and their active content which possesses antibacterial and antioxidant properties, represent a crucial solution in addressing the delayed healing of diabetic wounds. For this purpose, in this work we prepared hydrogel films made from a combination of carrageenan, chitosan, and curcumin, and subsequently evaluated their performance for potential application as the diabetic wound dressings. There were three hydrogel film formulations fabricated using 0.5% chitosan, 0.05% curcumin, and carrageenan at varying concentrations of 1%, 1.5%, and 2%, which were subsequently designated as A1, A2, and A3, respectively. These films were examined for physical parameters, chemical profiles, antibacterial activity against Staphylococcus aureus and Escherichia coli, and antioxidant activity (DPPH assay). The A2 film formulation demonstrated optimal characteristics, as evidenced by a high swelling capacity of 1439.67 ± 20.36%, an appropriate moisture content of 20.63 ± 0.49%, a film pH of 6.23 ± 0.31%, favorable degradation behavior of 93.27 ± 1.36%, and a film thickness of 0.20 ± 0.001 mm. This formulation also demonstrated superior antibacterial activity against Staphylococcus aureus and Escherichia coli, accompanied by strong antioxidant activity (IC50 = 74.52 ppm). Such results indicate that the carrageenan/chitosan/curcumin hydrogel film, particularly formulation A2, is a promising smart hydrogel dressing candidate for diabetic wound applications.