Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

1.578

P-Index

This Author published in this journals

All Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Jurnal Ilmiah Universitas Batanghari Jambi Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Respirasi (JR) Biomolecular and Health Science Journal Indian Journal of Forensic Medicine & Toxicology

Resti Yudhawati

Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya, Indonesia.

Author-ID : 359632

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

Published : 20 Documents Claim Missing Document

Claim Missing Document

Articles

1 2

Peran Imunitas Mukosa terhadap Infeksi Mycobacterium Tuberculosis: [The Role of Mucosal Immunity in Mycobacterium tuberculosis Infection] Irmi Syafa’ah; Resti Yudhawati
Jurnal Respirasi Vol. 2 No. 2 (2016): Mei 2016
Publisher : Faculty of Medicine Universitas Airlangga

Tuberculosis (TB) is one of major health problems in the world, with high morbidity and mortality rates. According to Global Tuberculosis Report 2015, Indonesia ranks as country with the 2nd highest number of TB cases in the world. Airway was described as a ‘gateway’ to the main pathogens, allergens and particles from the external environment. It has surveillance function that filtering beneficial and non-beneficial antigens, including Mycobacterium tuberculosis (MTB) as the causative agent of TB. MTB is a mucosal transmitted pathogen, infects human through mucosal tissue of respiratory tract. Airway mucosa was considered as the first barrier as well as inductive sites to initiate mucosal immune response against MTB. In this literature, the role of mucosal immune system, in this case especially airway mucosa, and its role against Mycobacterium tuberculosis infection in humans will be further discussed.

Imunopatogenesis Penyakit Paru Obstruktif Kronik : [Immunopathogenesis Update of COPD] Resti Yudhawati; Yuyus Dwi Prasetiyo
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory airway disease and complicated lung tissue. The airways of patients with COPD contain many inflammatory cells including neutrophils, macrophages, CD8 T lymphocytes, CD4 T lymphocytes and dendritic cells, each of which has its own role and interacts with COPD immunopathogenesis. The inflammatory response in people with COPD involves innate immunity (neutrophils, macrophages, eosinophils, mast cells, natural killer cells, and dendritic cells) and adaptive immunity (T and B lymphocytes), but there is also activation of structual cells such as alveolar epithelial cells endothelial cells and fibroblasts. Inflammation of the respiratory tract in COPD will persist even after quitting smoking, this can be caused by damage to the extracellular matrix will release proinflammatory cytokines which are neutrophil and monocyte chemotaxis, impaired alveolar macrophages which result in impaired cleaning of apoptotic cells and pathogenic microbes and oxidative stress will cause DNA double chain damage.

Peran Steroid pada Pneumocystis Pneumonia Ditinjau Berdasarkan Imunopatogenesis : [Immunopathogenesis of Steroid in Pneumocystis Pneumonia] Resti Yudhawati; Whendy Wijaksono
Jurnal Respirasi Vol. 5 No. 2 (2019): Mei 2019
Publisher : Faculty of Medicine Universitas Airlangga

Pneumocystis Pneumonia (PCP) is a potentially life-threatening infection that can occur in individuals who are immunocompromised. In PCP steroid use is still recommended especially in patients with moderate and severe severity. Corticosteroids are given along with anti-pneumocystis therapy and are known to reduce the incidence of mortality and respiratory failure associated with PCP. Innate immunity and adaptive immunity are symbiotic relationships to provide optimal defense for the lungs and other organs and tissues from infection PCP. The corticosteroid mechanism in PCP is based on an anti-inflammatory mechanism especially its role in inhibiting neutrophils. Many clinicians believe the administration of anti-pneumocystis causes the acceleration of inflammation. Because the inflammatory process increases when anti-pneumocystis therapy is started, corticosteroid therapy is useful before inflammation occurs which causes extensive damage to the lungs.

First-Line Anti-Tuberculosis Drug Resistance Pattern Ayurveda Zaynabila Heriqbaldi; Rebekah Juniati Setiabudi; Resti Yudhawati
Jurnal Respirasi Vol. 8 No. 1 (2022): January 2022
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: An important concern regarding TB currently is the case of anti-TB drug resistance; hence research on resistance patterns and risk factors is essential. This study aimed to identify the pattern of first-line anti-TB drug resistance. Methods: This descriptive retrospective study was conducted at MDR-TB polyclinic Dr. Soetomo General Hospital, Surabaya, in 2017-2019. Only complete medical records were included. The variables were first-line anti-TB drug resistance (isoniazid, rifampicin, ethambutol, streptomycin) and patients’ characteristics (age, gender, treatment history, and comorbidities). The drug resistance test was performed using certified culture methods. Results: Among 239 patients, the incidences of resistance to H, R, E, and S were 79.08%, 94.14%, 25.94%, and 20.08%, respectively. The most common patterns were HR (42.26%), R (18.83%), and HRE (12.55%). The largest age group was 45-54 years old (38%). The dominant gender was male (56.49%). The most treatment history category was relapsed patients (48%) and there were more patients with comorbidity (57%). Conclusion: The highest incidence rate of resistance was rifampicin and the most common resistance pattern was HR. Most of the patients were of working age, male, relapse patients, and had comorbidities. An appropriate TB therapy treatment plays an important role in preventing resistance.

Pengaruh ï¢-Blocker Terhadap Prognosis Gagal Jantung Dengan/Tanpa Penyakit Paru Obstruktif Kronis Tafana Fadhillah Laili; Johanes Nugroho; Resti Yudhawati
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Gagal jantung merupakan sindroma klinis oleh adanya kelainan struktural maupun fungsional jantung. Gagal jantung sering dijumpai berdampingan dengan Penyakit Paru Obstruktif Kronis (PPOK). Penyakit komorbiditas antara gagal jantung dan PPOK memiliki keterkaitan sehingga memengaruhi pemilihan terapi. Pemberian b-blocker umum diberikan dalam perawatan pasien gagal jantung, sedangkan pada gagal jantung dengan PPOK dikenal cukup menguntungkan untuk menurunkan mortalitas dan menurunkan eksaserbasi. Untuk mengetahui pengaruh b-blocker terhadap prognosis gagal jantung dengan/tanpa PPOK ditinjau dari BNP, NT-proBNP, dan FEV-1. Penelitian ini merupakan systematic review dari literatur yang dipublikasi pada PubMed, Science Direct, dan ClinicalTrial.gov. Sampel penelitian yang sesuai dengan kriteria inklusi dan eksklusi melibatkan 5 literatur dengan total 459 partisipan. Unsur yang dianalisis yaitu efikasi ð›½-blocker terhadap nilai klinis meliputi FEV-1, NT- proBNP, dan plasma BNP pada pasien gagal jantung dengan/tanpa PPOK. Keseluruhan artikel yang ditelaah dalam systematic review ini merupakan studi Randomized Controlled Trials (RCT). Studi komparasi seluruh penelitian memaparkan penurunan kadar BNP dan NT-proBNP pada seluruh populasi gagal jantung dengan/tanpa PPOK lebih signifikan oleh pemberian carvedilol namun berisiko menurunkan nilai FEV-1 pada gagal jantung dengan PPOK. Pada pemberian bisoprolol tidak memiliki dampak yang signifikan terhadap perbaikan BNP atau NT-proBNP namun mampu meningkatkan hasil FEV-1 pada total populasi. Pemberian b-blocker pada gagal jantung dengan/tanpa PPOK dapat dijadikan pertimbangan sebagai terapi pilihan disesuaikan dengan selektivitas kinerja golongan obat dalam blokade reseptor serta perlu dilakukan titrasi dosis untuk mengetahui efek dosis minimum hingga toleransi maksimum.

IDENTIFICATION OF INFLUENZA VIRUSES IN HUMAN AND POULTRY IN THE AREA OF LARANGAN WET MARKET SIDOARJO-EAST JAVA, INDONESIA Frederika, Edith; Mareta, Aldise; Poetranto, Djoko; Wulandari, Laksmi; Setyoningrum, Retno Asih; Setyowati, Lucia Landia; Yudhawati, Resti; Soegiarto, Gatot; Yamaoka, Masaoki
Indonesian Journal of Tropical and Infectious Disease Vol. 4 No. 4 (2013)
Publisher : Institute of Topical Disease Universitas Airlangga

Background: Influenza is a viral infection that attacks the respiratory system (nose, throat, and lungs) that commonly known as "flu”. There are 3 types of influenza viruses, such as type A, type B, and type C. Influenza virus type A is the type of virus that can infect both human and animals, virus type B are normally found only in human, and Influenza virus type C can cause mild illness in human and not causing any epidemics or pandemics. Among these 3 types of influenza viruses, only influenza A viruses infect birds, particularly wild bird that are the natural host for all subtypes of influenza A virus. Generally, those wild birds do not get sick when they are infected with influenza virus, unlike chickens or ducks which may die from avian influenza. Aim: In this study, we are identifying the influenza viruses among poultry in Larangan wet market. Method: Around 500 kinds of poultry were examined from cloacal swab. Result: Those samples were restrained with symptoms of suspected H5. The people who worked as the poultry-traders intact with the animal everyday were also examined, by taking nasopharyngeal swab and blood serum. Conclusion: Identification of influenza viruses was obtained to define the type and subtype of influenza virus by PCR.

THE CLINICAL PROFILES OF AVIAN INFLUENzA IN ENDEMIC AND NON-ENDEMIC REGIONS IN INDONESIA. HOSPITAL-BASED STUDIES AND ITS IMPLICATION ON CLINICAL MANAGEMENT IN THE FUTURE Wibisono, Muhammad Jusuf; Meliana, Resti Yudhawati
Indonesian Journal of Tropical and Infectious Disease Vol. 1 No. 3 (2010)
Publisher : Institute of Topical Disease Universitas Airlangga

Indonesia is a greatest burden country of H5N1 avian influenza (AI) virus infection in the world, since first outbreak in Central Java 2005 until August 2010 there was 168 confirmed cases and 138 dead cases. The incidence increasing rapidly in widespread area endemic in Java, Sumatera, Bali and Sulawesi, and sporadic outbreaks in other areas. The World Health Organization stated that AI still became a treat in the next pandemic. H5N1 AI virus infection spreads in almost all provinces, but its endemic in Jakarta, Tangerang and Banten and in other area such Surabaya, Bali were sporadic outbreaks. There are 27 confirmed H5N1 AI infection cases in Jakarta from 296 suspected cases, while in Surabaya only 5 confirmed H5N1 AI infection cases from 12 suspected cases. The age of patient mean with H5N1 AI infection was 16.9 ± 11.6 yo in Jakarta and 24 ± 8.51 yo in Surabaya. There was no difference between male and female. Mortality rate was 77.7% in Jakarta and 60% in Surabaya. A large number of case has indirect contact history, predominantly by visiting market or areas where outbreaks of poultry disease. The clinical feature H5N1 AI virus infection could manifest as mild until severe pneumonia that often progress rapidly to ARDS. In Jakarta, 74% case showed abnormality chest radiography as bilateral pneumonia, while in Surabaya showed lobar pneumonia and bilateral pneumonia. Management patient of H5N1 AI infection is supportive therapy and antiviral, whereas a large number of cases needed mechanical ventilator support.

Screening Lung Cancer in Sampang Regency, Madura Through Empowerment and Health Cadres Formation Yudhawati, Resti; Wulandari, Laksmi; Febriani, Anna; Wati, Farah Fatma; Thendeyas, Richar Tomy; Atik, Nurul; Hariputri, Wulan Rahmawati; Novananda, Donny Ardika; Riyanto, Shandy Billy
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 10, No 2 (2024): June
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpkm.92549

Treatment for lung cancer remains challenging since most of the patients seek medical advice at an advanced stage of disease. Sampang is one of the regencies that refers many lung cancer patients in late stages to Dr. Soetomo Hospital, Surabaya, due to lack of information of lung cancer and early detection. Limited number of health workers to deliver comprehensive education to all areas requires community volunteers to fill this gap. The objective of this study was to educate and promote lung cancer awareness to the health cadres in Sampang as well as training them to early detecting individuals in the community with high-risk factors, as an attempt to bridge between the health workers and community, therefore the number of lung cancer early detection may be improved. Early identification of cancer may result in reduced morbidity and mortality, and in some cases, if detected early enough, therapy may involve only surgery. The education was provided for the health cadres by providing information related to lung cancer and guidance to fill the questionnaire and scoring of lung cancer risk factors. The participants' understanding was measured using a pretest-posttest design. Thirty health cadres have been successfully formed, and they have gained knowledge of lung cancer and mastered capability to perform early-screening of lung cancer in the community as shown by the increase of post-test result compared to pre-test. The health cadres then implemented their knowledge of lung cancer early-screening by distributing questionnaires of lung cancer risk factor scoring to residents using door to door methods. The questionnaires’ evaluation collected by the health cadres showed that there were 93 residents with high-risk factors of lung cancer. In conclusion, the health cadres has been capable to detect high-risk factors individuals in the community which further be followed up by community health workers comprehensively.

Case Report: Survival of A Coronavirus Disease-2019 (Covid-19) Patient with Acute Respiratory Distress Syndrome (ARDS) in Dr. Soetomo Hospital, Surabaya, Indonesia Soedarsono, Soedarsono; Semedi, Bambang Pudjo; Setiawati, Rosy; Meliana, Resti Yudhawati; Kusmiati, Tutik; Permatasari, Ariani; Bakhtiar, Arief; Syafa'ah, Irmi; Indrawanto, Dwi Wahyu
Folia Medica Indonesiana Vol. 56 No. 3 (2020): September
Publisher : Universitas Airlangga

An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China has spread rapidly in multiple countries of the world and has become a pandemic. Currently, there is no vaccine or specific antiviral for COVID-19. A study reported 7.3% of critical patients admitted to ICU, 71% of them required mechanical ventilation, and 38.5% of them were survived. Herein, we reported a 54 year old man with Acute Respiratory Distress Syndrome (ARDS) of COVID-19 who survived the disease. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of nasopharyngeal and oropharingeal swabs were positive for SARS-CoV-2. Diagnosis of ARDS was also according to clinical symptoms, laboratory, chest radiograph, and chest CT scan. Alcaligenes faecalis and Candida albicans were also identified from sputum culture. Treatment for this patient was causal and supportive therapy, including antibiotic, antiviral, and antifungal therapy according to the culture results, fluid resuscitation, and oxygen supply from the mechanical ventilator. This patient was survived and discharged on hospital day-29. A fibrosis in parenchyma pulmonary and sensory peripheral neuropathy occurred after survived from ARDS. Monitoring of clinical, laboratory, and chest radiograph were continued after the patient discharged from the hospital. This case highlights the importance of early diagnosis and effective treatment to the care of COVID-19 patient.

Profile of Nontuberculous Mycobacteria and Mycobacterium tuberculosis Detected in the Sputum of Pulmonary Tuberculosis Re-treatment Patients at Dr. Soetomo General Hospital Mochammad Afif Ziaulhaq; Mertaniasih, Ni Made; Meliana, Resti Yudhawati; Permatasari, Ariani
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 1 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i1.64176

Tuberculosis (TB) remains one of the leading infectious diseases worldwide. Despite global efforts to control TB, it remains a major public health issue, affecting 10.6 million people annually in 2021, with significant morbidity and mortality, particularly in resource-limited settings. Effective treatment of TB requires strict adherence to long-term medication, but challenges such as treatment failure, relapse, and loss to follow-up complicate outcomes. This is especially concerning for patients with comorbidities such as diabetes, HIV, or hypertension, which not only increase the risk of TB but also hinder its treatment and elevate the likelihood of nontuberculous mycobacteria (NTM) infections. This study aimed to analyze 326 pulmonary TB retreatment cases at Dr. Soetomo General Academic Hospital from October 2023 to April 2024. The retrospective design identified that 323 cases involved MTB and 3 involved NTM. The findings show that loss to follow-up was the most common reason for retreatment, particularly among males and older adults. Comorbidities were found to exacerbate treatment challenges, with some retreatment cases lasting up to 24 months. The study concludes that loss to follow-up remains a major risk factor for TB retreatment, particularly in MTB cases, and highlights the importance of managing comorbidities to improve treatment outcomes.

Co-Authors Aldise M Nastri Aldise Mareta Nastri Aldise Mareta, Aldise Atik, Nurul Ayurveda Zaynabila Heriqbaldi Bakhtiar, Arief Bakhtiar, Arief Bramantono Bramantono, Bramantono Desak Putu Agung Krisdanti Djoko Poetranto, Djoko Edith Frederika, Edith Emmanuel Djoko Poetranto Erwin Winaya Febriani, Anna Gatot Soegiarto Hariputri, Wulan Rahmawati Indiastuti, Danti Nur Indrawanto, Dwi Wahyu Johanes Nugroho Kazufumi Shimizu Kowiy Akbar Kusmiati, Tutik Laksmi Wulandari Landia Setiawati Lucia Landia Setyowati, Lucia Landia Luh Ade Wilan Krisna Masaoki Yamaoka Masaoki Yamaoka, Masaoki Megawati Rif’atyyah Nozomi Guntur Mochammad Afif Ziaulhaq Muhammad Jusuf Wibisono, Muhammad Jusuf Muhammad Raihan Habibi Musofa Rusli Ni Made Mertaniasih Nitya Prasanta Novananda, Donny Ardika Nurjanah Lihawa Permatasari, Ariani Pius Sebastian Ginting Rebekah Setiabudi, Rebekah Retno A Setyoningrum Retno Asih Retno Asih Setyoningrum Riyanto, Shandy Billy Rosyid, Alfian Nur Semedi, Bambang Pudjo Setiawati, Rosy Soedarsono Soedarsono Syafa'ah, Irmi Syafa’ah, Irmi Tafana Fadhillah Laili Thendeyas, Richar Tomy Wati, Farah Fatma Whendy Wijaksono Yuyus Dwi Prasetiyo

Title

Found 20 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 20 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 20 Documents
Search