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All Journal Prosiding Seminar Biologi Current Biochemistry PROSIDING SEMINAR KIMIA Reswara: Jurnal Pengabdian Kepada Masyarakat Community Empowerment Jurnal Nuansa Akademik: Jurnal Pembangunan Masyarakat Proceeding Biology Education Conference Jurnal Pengabdian Masyarakat Kedokteran Gemakes: Jurnal Pengabdian Kepada Masyarakat Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Jurnal Farmasi Sains dan Praktis Indonesian Journal of Medical and Pharmaceutical Science
Dwi Endah Kusumawati
Program Studi Sarjana Farmasi, Universitas Islam Sultan Agung, Semarang
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EDUKASI DAN WORKSHOP PEMANFAATAN BUNGA TELANG MENJADI TEH ANTIOKSIDAN PADA SISWA SDN PEDURUNGAN KIDUL 04 SEMARANG Kusumawati, Dwi Endah; Putri, Chintia Nindya
GEMAKES: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2023): GEMAKES: Jurnal Pengabdian Kepada Masyarakat
Publisher : Politeknik Kesehatan Kemenkes RI Jakarta I

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36082/gemakes.v3i2.1096

Abstract

Salah satu cara menjaga imunitas tubuh adalah mengkonsumsi minuman herbal yang mengandung antioksidan. Anak-anak diketahui lebih rentan terpapar penyakit dibandingkan dengan usia produktif, sehingga pengetahuan terkait kesehatan terutama upaya peningkatan daya tahan tubuh dan pemanfaatan tanaman herbal yang mengandung antioksidan perlu ditanamkan sejak dini. Kegiatan ini bertujuan memberikan edukasi terkait pemanfaatan tanaman herbal yaitu bunga telang yang mengandung antioksidan. Kegiatan dimulai dengan pre-test, kemudian dilanjutkan edukasi dan workshop, serta diakhiri dengan post-test. Kegiatan berjalan lancar dan terdapat peningkatan pengetahuan serta keterampilan siswa dalam pemanfaatan bunga telang menjadi teh antioksidan sebesar 93-100%. Artinya, siswa telah memahami pemanfaatan bunga telang menjadi teh antioksidan.
Evaluasi Sifat Fisik Sediaan Sabun Cair Ekstrak Bunga Telang (Clitoria ternate) Dwi Endah Kusumawati; Rega Puspitasari
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.147

Abstract

Background: Antiseptic liquid soap is increasingly popular with the public. The antibacterial substance that is usually contained in antiseptic liquid soap is triclosan, which when used in the long term can disrupt the balance of the normal flora on the skin, so natural ingredients are needed to replace the use of triclosan. One of the natural ingredients that can be used is butterfly pea. The aim of the study was to evaluate the physical properties of the butterfly pea liquid soap (organoleptic, pH, specific gravity, viscosity and foam stability) in accordance with the requirements listed in the SNI for liquid soap. Methods: This study is an analytical experiment, namely testing and analyzing the characteristics of butterfly pea liquid soap which consists of: organoleptic (consistency, color, aroma), pH, viscosity, and foam stability. Results: Hand washing liquid soap with butterfly pea flower extract complies with SNI requirements, with details: purple in color with slightly thick consistency, pH 4.5 – 5 , specific gravity 1.02 – 1.03 g/mL, viscosity 3456.33 – 6375.33 cP with foam stability of 93%. Conclusion: The physical characteristics of liquid hand washing soap with the active ingredient of butterfly pea flower extract comply with the requirements of SNI and have a purple color due to the presence of anthocyanin.
Pengaruh Waktu Dan Suhu Ekstraksi Daun Melinjo (Gnetum Gnenom L.) terhadap Aktivitas Antioksidan Windi Susmayanti; Dwi Endah Kusumawati
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.154

Abstract

Background: The widely cultivated melinjo leaf, or Gentum L genome, is the most valuable commodities cause it contains phenolic chemicals that have antioxidant properties. It is possible to get phenolic chemicals from melinjo leaves by macerating them in ethanol, typically at room temperature. By raising the temperature and length of the extraction process, the yield-maximizing extraction process can be hastened. Methods: The objective of this study is to ascertain the antioxidant activity of melinjo leaves that have been ethanol extracted at 45, 60, and 75 °C. For each temperature change, extraction was done using 96% ethanol (1:10, w/v) for 30 and 45 minutes. The yield, phytochemical assay, total phenolic, and antioxidant activity using the The CUPRAC technique is the variables tested in this study. Results: According to research findings, temperature and extraction time have an impact on yield, content phenolic total, and antioxidant activity. An extract with the maximum antioxidant activity and the consistent phenol content 105.97±5.53 mg GAE/ml and Ic50 of 59.7953 was produced after 45 minutes of extraction at 60°C, but the yield was only 2.22%.
Antibacterial Test of Endophytic Bacteria Isolated from Jawer Kotok (Coleus scutellarioides L. Benth) Against Bacillus cereus and Salmonella enteritidis Dwi Endah Kusumawati; Maria Bintang
Current Biochemistry Vol. 10 No. 1 (2023)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.10.1.2

Abstract

The use of synthetic antibiotics in small doses and long term against pathogenic bacteria can cause negative effects, such as resistance of pathogens and killing of good bacteria. We needs an innovation to substitute the use of synthetic antibiotics with natural antimicrobial compounds. Jawer kotok (Coleus scutellarioides L. Benth) has been used as medicinal plant and shown to be efficacious as antimicrobial because it contains flavonoids, tannins, alkaloids and saponins. Endophytic bacteria are symbiotic microorganisms that live in healthy plant tissue without harming to the host plant and may produce natural antimicrobial compounds which similar to the host plant. The aim of this study are to isolating endophytic bacteria from jawer kotok and screening their antibacterial activity against two pathogenic bacteria, namely Bacillus cereus and Salmonella enteritidis. A total of 22 bacterial isolates were obtained from C scutellarioides [L.] Benth. Based on antibacterial activity test, nine isolates shown antibacterial activity against B. cereus and S.enteritidis. BJ7 is the most potential isolate because it shown the biggest inhibition. It great possible that endophytic bacteria from jawer kotok may synthesize the same antimicrobial compounds like their host plant.
PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF FOOTSPRAY CONTAINING HONEY PINEAPPLE PEEL EXTRACT (ANANAS COMOSUS [L.] MERR) Kusumawati, Dwi Endah; Rahmadani, Azmi; Puspitasari, Rega Putri; Ghazi, Fahreza Maulana; Husna, Ahmad Nida'ul
Jurnal Farmasi Sains dan Praktis Vol 9 No 3 (September-December 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i3.8829

Abstract

Foot odor or bromhidrosis occurs due to the activity of bacteria that convert leucine in sweat into isovaleric acid which results in unpleasant odors. Honey pineapple skin (Ananas comosus [L.] Merr) is generally waste, whereas honey pineapple skin is known to contain antibacterial compounds. The aim of this study is to determine the potential of honey pineapple peel as an active ingredient in footspray based on the results of phytochemical screening and physical evaluation. Honey pineapple peel was extracted by maceration method using ethanol 70% then phytochemical test. Footspray preparations were made with various extract concentrations of 0%, 25%, 35% and 45% then tested for organoleptic, pH, specific gravity, viscosity, homogeneity, spreadability, and dry time during storage period of 0, 7, 14 and 21 days at room temperature. This study showed that honey pineapple peel extract contained flavonoids, tannins, phenols and alkaloids. The footspray has brown color with honey pineapple scent, pH of 5.71-6.37, specific gravity 1.05-1.09 g/mL, viscosity 7.2-13.2 cP, spreadability 6.67-7.60 cm, and the dry time is 4-5 minutes. Footspray containing honey pineapple peel extract with concentrations of 25%, 35% and 45% has a pH value that is safe for the skin, with good specific gravity, viscosity, homogeneity and spreadability, also stable during storage. Formula 1 (25% extract concentration) tends to be preferred because its texture is soft and not too sticky when applied to the skin when compared with formula 2 and 3.
Education on the utilization of butterfly pea flower (Clitoria ternatea) as a natural dye for students of SDN Tlogosari Wetan 2 Semarang Kusumawati, Dwi Endah; Rizki, Inesya Febrianing; Lestari, Asih Puji; Nabilla, Nabilla; Nurningtyas, Hasna Labibah; Chaqi, Muhammad Dhiya'ul; Prasetyo, Adhi
Community Empowerment Vol 10 No 3 (2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12728

Abstract

Butterfly pea flower is rich in anthocyanins, which not only provide a natural blue color but also offer health benefits. The purpose of this community service is to educate students about the benefits of butterfly pea flower as a natural dye. The activity began with an introduction to butterfly pea flower and anthocyanins, followed by practical application of using butterfly pea flower as a natural dye in making pudding. This activity successfully increased students' knowledge about the use of natural dyes from butterfly pea flower by 100%. When applied to pudding, butterfly pea flower, which contains anthocyanins, proved to be usable as a natural dye. In addition, this activity also educated students about the diversity of local food ingredients that can be optimally utilized.
EDUKASI EDIBLE FLOWER SEBAGAI ANTIOKSIDAN ALAMI MENGGUNAKAN MEDIA FLASHCARD PADA SISWA SEKOLAH DASAR Kusumawati, Dwi Endah; Mutiasari, Amy
Reswara: Jurnal Pengabdian Kepada Masyarakat Vol 4, No 1 (2023)
Publisher : Universitas Dharmawangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46576/rjpkm.v4i1.2602

Abstract

SDN Pedurungan Kidul 04 merupakan salah satu penyelenggara kegiatan Pendidikan di Kota Semarang. Penggunaan media dalam mendukung proses belajar mengajar biasanya menggunakan papan tulis dan LCD. Kegiatan pengabdian dilaksanakan pada 21 Oktober 2022, dengan sasarannya adalah siswa kelas V. Salah satu materi pada buku Tematik Terpadu adalah makanan sehat. Pengenalan edible flower yang mengandung antioksidan alami dan dapat dimanfaatkan sebagai makanan atau minuman kesehatan perlu untuk diperkenalkan sejak dini guna meningkatkan literasi sains siswa. Berdasarkan situasi belum ada siswa yang mengetahui pemanfaatan edible flower sebagai bunga tidak beracun yang dapat dikonsumsi dan bermanfaat bagi kesehatan karena mengandung antioksidan. Tujuan kegiatan ini adalah mengedukasi siswa terkait edible flower yang mengandung antioksidan alami melalui media pembelajaran yang inovatif, mudah dipahami dan menyenangkan. Edukasi tentang edible flower, jenis-jenis edible flower dan manfaatnya sebagai antioksidan alami disampaikan dengan metode presentasi menggunakan media flashcard. Kegiatan diawali dan diakhiri dengan pembagian kuesioner guna mengukur peningkatan pengetahuan siswa. Berdasarkan hasil kegiatan, terjadi peningkatan pengetahuan siswa terkait edible flower sebesar 90%, jenis-jenis edible flower sebesar 80%, definisi antioksidan sebesar 80%, dan pemanfaatan edible flower sebagai sumber antioksidan alami sebesar 95%. Artinya, media flashcard terbukti mampu meningkatkan minat dan pengetahuan siswa terhadap materi pembelajaran yang disampaikan. Harapannya media flashcard dapat dimanfaatkan guru sebagai salah satu inovasi metode pembelajaran yang menarik, efektif dan menyenangkan
Systematic Literature Review Potensi Daun Ketepeng Cina (Cassia alata.L) Sebagai Antijamur Pada Dermatofitosis Cahyani, Nur; Kusumawati, Dwi Endah
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 2 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i2.447

Abstract

Background: Indonesia has a tropical climate suitable for fungal growth. Some fungal species are flora that can cause diseases in humans, for example dermatophytosis. The ketepeng cina plant (Cassia alata L.) is empirically known to have various medicinal properties. Some of its benefits include treating worms, canker sores, constipation, tinea versicolor, ringworm, scabies, and reducing itching. The part often used as medicine is the leaves. This study, a literature review, aims to find substances found in ketepeng cina leaves that have antifungal activity on dermatophytosis, which fungi cause dermatophytosis that are inhibited, and the antifungal mechanisms of ketepeng cina leaves. Methods:This study applies a systematic literature review method with data collection using the PRISMA approach (Primary Reporting System for Systematic Reviews and Meta-analyses). The search for articles in this study was conducted using the Google Scholar, ScienceDirect, and PubMed databases, and after analysis, six relevant articles were obtained. Results: The analysis results show that ketepeng cina leaf extract is able to inhibit the growth of Trichophyton rubrum, Trichophyton sp, Microsporum canis, and Malassezia globosa, fungi that cause dermatophytosis infections such as tinea pedis (athlete's foot), tinea cruris (eczema), tinea capitis (ringworm of the scalp) and tinea imbricata (ringworm / pile-up lesions). Conclusion: The active compounds that play a role in antifungal activity include anthraquinones, flavonoids, saponins, tannins, and terpenoids. The mechanism of action of these compounds includes damaging cell membranes, inhibiting the development of fungal hyphae, can suppress fungal growth, damaging fungal sterols which are the main layer of fungi, causing disruption of nutrient absorption needed for fungal growth, so that cells will enlarge and collapse, inhibiting the production of nucleic acids, proteins, and phospholipid membranes.
Co-Authors Adhi Prasetyo, Adhi Amy Mutiasari Asih Puji Lestari Chaqi, Muhammad Dhiya'ul Desriani Desriani Dina Fatmawati Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Ghazi, Fahreza Maulana Husna, Ahmad Nida'ul Lestari, Asih Puji Maria Bintang MARIA BINTANG Mifta Triwahyuni Mutiasari, Amy Nabilla Nabilla Neneng Hasanah Nita Tiara Luthfiah Nur Cahyani Nurningtyas, Hasna Labibah Purwanto, Ukhradiya Magharaniq Safira Puspitasari, Rega Putri Putri, Chintia Nindya Putri, Chintiana Nindya Rahmadani, Azmi Rega Puspitasari Rizki, Inesya Febrianing Siti Zubaidah Syamsul Falah Wilda Fhitriany Usman Windi Susmayanti Wiwit Amrinola