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All Journal Jurnal Kedokteran Diponegoro Science Midwifery Indonesian Journal of Global Health research Jurnal Health Sains Cermin Dunia Kedokteran Journal Of World Science Jurnal Sehat Indonesia (JUSINDO) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Mahasiswa Ilmu Kesehatan Cermin Dunia Kedokteran Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal) Glosains: Jurnal Sains Global Indonesia

Puguh Riyanto

Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Diponegoro, Semarang, Indonesia

Author-ID : 362167

Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Association between Bubble Tea Consumption and Prevalence of Acne Vulgaris Devina Subagio; Asih Budiastuti; Puguh Riyanto; Yulian Ludovicus Aryoko Widodo
Cermin Dunia Kedokteran Vol 48, No 7 (2021): Infeksi - [Covid - 19]
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i7.1450

Introduction: Acne vulgaris (AV) is one of the most common skin disorders among youth. A cross-sectional study was conducted to analyze the association between bubble tea consumption and the prevalence of acne vulgaris among medical students. Method: Subjects were obtained from consecutive sampling. There were 91 eligible subjects meeting inclusion criteria. Data was collected using questionnaires. Examinations were through observation of photographs of lesions. Chi-square analysis was conducted at a 95% confidence interval (p<0.05). Results: Data were collected from 91 medical students with mean age 19.62+0.98 year-old. The prevalence of acne was 58.2%; mostly in age 20 years (37.7%). There is a significant association between consumption of bubble tea and the prevalence of AV (p<0.001). Conclusion: Bubble tea consumption is associated with prevalence of acne vulgaris.Pendahuluan: Akne vulgaris merupakan salah satu penyakit kulit yang umum dialami pada dewasa muda. Metode: Penelitian observasional cross sectional untuk mengetahui asosiasi konsumsi bubble tea dengan kejadian akne vulgaris. Sampel diambil dengan metode consecutive sampling menghasilkan 91 mahasiswa yang memenuhi kriteria inklusi dan eksklusi. Pengambilan data primer dengan kuesioner. Pemeriksaan fisik observasi kulit responden dengan foto. Analisis data menggunakan uji Chi-Square dengan tingkat kemaknaan p<0,05. Hasil: Angka kejadian akne vulgaris adalah 58,2% dengan rata-rata usia 19.62+0.98; usia terbanyak penderita adalah 20 tahun (37,7%). Terdapat asosiasi bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris (p<0,001). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris.

Association between Bubble Tea Consumption and Prevalence of Acne Vulgaris Devina Subagio; Asih Budiastuti; Yulian Ludovicus Aryoko Widodo; Puguh Riyanto
Cermin Dunia Kedokteran Vol 48 No 7 (2021): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i7.91

Introduction: Acne vulgaris (AV) is one of the most common skin disorders among youth. A cross-sectional study was conducted to analyze the association between bubble tea consumption and the prevalence of acne vulgaris among medical students. Method: Subjects were obtained from consecutive sampling. There were 91 eligible subjects meeting inclusion criteria. Data was collected using questionnaires. Examinations were through the observation of photographs of lesions. Chi-square analysis was conducted at a 95% confidence interval (p<0.05). Results: Data were collected from 91 medical students with a mean age of 19.62+0.98-year-old. The prevalence of acne was 58.2%, mainly at the age of 20 (37.7%). There is a significant association between consumption of bubble tea and the prevalence of AV (p<0.001). Conclusion: Bubble tea consumption is associated with the prevalence of acne vulgaris. Pendahuluan: Akne vulgaris merupakan salah satu penyakit kulit yang umum dialami pada dewasa muda. Metode: Penelitian observasional cross-sectional untuk mengetahui asosiasi konsumsi bubble tea dengan kejadian akne vulgaris. Sampel diambil dengan metode consecutive sampling menghasilkan 91 mahasiswa yang memenuhi kriteria inklusi dan eksklusi. Pengambilan data primer dengan kuesioner. Pemeriksaan fisik observasi kulit responden dengan foto. Analisis data menggunakan uji Chi-Square dengan tingkat kemaknaan p<0,05. Hasil: Angka kejadian akne vulgaris adalah 58,2%, dengan rata-rata usia 19,62+0,98; usia terbanyak penderita adalah 20 tahun (37,7%). Terdapat asosiasi bermakna antara konsumsi bubble tea dan kejadian akne vulgaris (p<0,001). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konsumsi bubble tea dan kejadian akne vulgaris.

Post COVID-19 Immunization Herpes Zoster Reactivation In Asia : A Literature Review Nurul Nisa Ulfa; Danisa Diandra Safarina; Puguh Riyanto
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 4 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i3.37292

Background: The COVID-19 vaccine that targets viral mRNA has been created and can be used as an effort to end the COVID-19 pandemic that has hit the world since 2020. The COVID-19 vaccine currently being developed has proven its effectiveness and safety in the general adult population.Objective: To identify reactivation of Herpes Zoster virus post COVID-19 vaccine.Methods: This article review discusses four case reports of Herpes Zoster following the COVID-19 immunization in Asia which were obtained from various sources such as Pubmed Medline Embase.Results: The mRNA-type vaccine is associated with skin manifestations with an increased incidence (14.4%) of Herpes Zoster which was observed around 6-8 days after administration of the first dose of vaccine (BNT162b2 vaccine) and 1.5% after administration of the mRNA- 1273 which occurred in the Asian Oceanian race. COVID-19 vaccine substances such as polyethylene glycol (PEG), the polysorbate present in mRNA vaccines, and polysorbate 80 are suspected causing an allergic reactions.Conclusion: Health workers must be careful in administering the COVID-19 vaccine, especially to individuals who have risk factors that can decrease their immune system so it can cause reactivation of Herpes Zoster.

Literature Review: The Role of Saffron (Crocus sativus L) in Cosmetic Dermatology Damayanti, Galih Sari; Riyanto, Puguh
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 6 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i6.40711

Background : Crocus sativus L known as saffron is widely discussed in Indonesia. Although saffron has been used since ancient times for medicinal and cosmetic purposes, scientific research on the mechanism of saffron in its role in promoting skin health is lacking. Objectives : This literature review is to determine the role of saffron in cosmetic dermatology. Methods : This article is a narrative research. The library sources that used was carried out through the database Google Scholar, PubMed, and Cochrane. The article search does not limit study design or study level. All articles were searched from 2012 to June 2023. The study inclusion criteria included: data available in English and Indonesian. Exclusion criteria were articles on the benefits of using saffron in the other field of dermatology and the use of saffron in combination with other topical active ingredients. Results : There were 16 articles which meet the criterias. It was found that saffron play role in the cosmetic dermatology such as in skin aging, melasma, as a photoprotection agents, skin moisturizer, prevention and treatment of skin cancer, as well as preparation of cosmetic products. Saffron has antioxidant, antiinflammatory, antipigmentation, antiwrinkle, anticarcinogenic and photoprotective activities. Conclusion : Crocus sativus L is a natural ingredient that has the potential to be further developed into medicinal forms, both oral and topical preparations because it is proven to have various pharmacological effects that play role in the cosmetic dermatology.

The Effect of Topical 0.1% Pomegranate Extract (Punica Granatum) on Trans Epidermal Water Loss (Tewl) and Skin Ph Levels in Patients with a History of Atopic Dermatitis Fernandes, Albert; Widayati, Retno Indar; Riyanto, Puguh
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1353

Repairing the skin barrier with moisturizers is one of the five main pillars of treating atopic dermatitis. Petrolatum is considered the gold standard, but its consistency is too thick and oily making it less comfortable to use. Moisturizers containing pomegranate extract (Punica granatum) can be an alternative choice that is more comfortable to use. The effectiveness of this pomegranate extract can be eval__uated using TEWL and pH examinations which are considered accurate indicators for changes in skin barrier conditions. Effectiveness of topical administration of 0.1% pomegranate extract in reducing TEWL and skin pH in sufferers with a history of AD.Single blind randomized clinical trial with two parallel group pre and post design. 34 sufferers with a history of AD were randomly divided into treatment groups (topical 0.1% pomegranate extract, 17 subjects) and control group (topical 100% petrolatum, 17 subjects). Moisturizer was applied twice daily to the volar area of the forearm for 4 weeks. Both groups showed a significant decrease in TEWL after 4 weeks with a TEWL delta of -5.2±2.31g/m2/hour (p<0.001) in the pomegranate extract group and-7.0±7.95g/m2/hour(p=0.003) in the petrolatum group. There was no significant difference in TEWL reduction between the two study groups.The pomegranate extract group showed a significant decrease in pH after 4 weeks with a pH delta of -0.5±0.10(p<0.001), while the petrolatum group actually showed a slight increase with a pH delta of0.0±0.59 (p=0.6). The pomegranate extract group showed a significantly greater decrease in pH (p<0.001).Topical 0.1% pomegranate extract is as effective as 100% petrolatum in reducing TEWL, but more effective in lowering skin pH.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i7.91

Introduction: Acne vulgaris (AV) is one of the most common skin disorders among youth. A cross-sectional study was conducted to analyze the association between bubble tea consumption and the prevalence of acne vulgaris among medical students. Method: Subjects were obtained from consecutive sampling. There were 91 eligible subjects meeting inclusion criteria. Data was collected using questionnaires. Examinations were through the observation of photographs of lesions. Chi-square analysis was conducted at a 95% confidence interval (p<0.05). Results: Data were collected from 91 medical students with a mean age of 19.62+0.98-year-old. The prevalence of acne was 58.2%, mainly at the age of 20 (37.7%). There is a significant association between consumption of bubble tea and the prevalence of AV (p<0.001). Conclusion: Bubble tea consumption is associated with the prevalence of acne vulgaris. Pendahuluan: Akne vulgaris merupakan salah satu penyakit kulit yang umum dialami pada dewasa muda. Metode: Penelitian observasional cross-sectional untuk mengetahui asosiasi konsumsi bubble tea dengan kejadian akne vulgaris. Sampel diambil dengan metode consecutive sampling menghasilkan 91 mahasiswa yang memenuhi kriteria inklusi dan eksklusi. Pengambilan data primer dengan kuesioner. Pemeriksaan fisik observasi kulit responden dengan foto. Analisis data menggunakan uji Chi-Square dengan tingkat kemaknaan p<0,05. Hasil: Angka kejadian akne vulgaris adalah 58,2%, dengan rata-rata usia 19,62+0,98; usia terbanyak penderita adalah 20 tahun (37,7%). Terdapat asosiasi bermakna antara konsumsi bubble tea dan kejadian akne vulgaris (p<0,001). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konsumsi bubble tea dan kejadian akne vulgaris.

The Relationship Between Occupation and Incidence of Various Types of Melanocytic Nevi Riyanto, Puguh; Alexander, Lim
Jurnal Health Sains Vol. 6 No. 7 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i7.2671

Melanocytic nevi (MN) are benign proliferations of melanocytes influenced by genetic and environmental factors, particularly ultraviolet (UV) radiation. Occupational exposure to sunlight may contribute to the development of different nevus types, but this relationship remains underexplored. This study aimed to examine the association between occupation and the incidence of various melanocytic nevi types. A descriptive observational study with a cross-sectional design was conducted among 20 participants in Semarang, Indonesia, from April to May 2025. Data were collected via validated questionnaires covering occupation (indoor/outdoor), protective measures (sunscreen, long-sleeved clothing), and nevus types (junctional, compound, intradermal). Statistical analysis was performed using SPSS. Results showed that 60% of participants had indoor occupations, while 40% worked outdoors. Among nevus types, 50% had compound nevi, 16% had junctional nevi, and 10% had intradermal nevi. A significant association was found between outdoor occupations and compound nevi (p = 0.010, RR = 3.50). No significant links were observed for junctional or intradermal nevi. Protective measures, such as sunscreen use, showed no significant impact, possibly due to low adherence (70% non-users). The findings suggest that occupational UV exposure may elevate the risk of compound nevi. Further research with larger samples and additional variables (e.g., sun exposure duration) is recommended to validate these results and to inform preventive strategies for at-risk populations.

Influential Host Factors to the Incidence of HIV/AIDS in Key Populations in Pati District Murtono, Dwi; Riyanto, Puguh; Shaluhiyah, Zahroh
Kesmas Vol. 13, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Human Immunodeficiency Virus (HIV) dan Acquired Immune Deficiency Syndrome (AIDS) merupakan penyakit berbahaya di dunia yang salah satu metode penularannya adalah melalui hubungan seksual. Penelitian ini bertujuan menjelaskan faktor-faktor yang berpengaruh terhadap kejadian HIV/AIDS pada populasi kunci. Penelitian dilakukan dari bulan Maret sampai September 2016. Penelitian analitik observasional dengan rancangan kasus kontrol pada populasi kunci di Kabupaten Pati. Kasus sebanyak 53 pasien positif HIV/AIDS, sedangkan kontrol sebanyak 53 pasien negative HIV/AIDS.Pengambilan sampel menggunakan teknik consecutive sampling. Data diperoleh dari riwayat medis dan wawancara kuesioner. Penelitian ini menggunakan uji kai kuadrat pada analisis bivariat dan regresi logistik ganda pada analisis multivariat. Hasil penelitian menunjukkan bahwa faktor yang berpengaruh terhadap kejadian HIV/AIDS pada populasi kunci dalam penelitian ini adalah perilaku pemakaian kondom, riwayat menderita infeksi menular seksual, dan bentuk aktifitas seks kombinasi. Faktor yang tidak berpengaruh adalah perilaku multi pasangan seks, perilaku penggunaan aksesoris seks, perilaku penggunaan jarum tato, dan perilaku penggunaan narkoba suntik. Sebagai kesimpulan, faktor yang berpengaruh terhadap kejadian HIV/AIDS yaitu perilaku pemakaian kondom yang tidak konsisten, riwayat menderita IMS dan bentuk aktivitas seks kombinasi. Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) are serious diseases in the world in which one of transmission methods is through sexual intercourse. This study aimed to explain the influential host factors to the incidence of HIV/AIDS in key populations. The study was conducted in March-September 2016. The study was observational analytic with case-control design in key populations in Pati District. Cases were 53 patients living with HIV/AIDS, while controls were 53 patients not living with HIV/AIDS. The sampling technique employed was consecutive sampling. Data were obtained from medical records and interview questionaire. This study applied chi-square test to analyze bivariate data, and multiple logistic regression to analyze multivariate data. Results indicated that the influential factors to the incidence of HIV/AIDS in key populations were inconsistent condom use behavior, records of suffering from sexually-transmitted infections (STIs), and forms of sexual activity. While, factors which were not influential to the incidence of HIV/AIDS were multiple sex partner behavior, sex accessory use behavior, tattoo needle use behavior, injecting drug use behavior. In conclusion, several influential factors to the incidence of HIV/AIDS in key populations are the inconsistent condom use behavior, records of suffering from STIs, and forms of sexual activity.

Comparison of the effectiveness of colloidal oatmeal 1% with petrolatum 100% to repair the skin bars in psoriasis vulgaris: A study of trans-epidermal water loss Riyanto, Puguh; Sugianto, Yosep Ferdinand Rahmat; Z, Mutia Dian Permatasari Mochtar
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2118

The purpose of this study was to compare the effectiveness of 1% colloidal oatmeal with 100% petrolatum in improving the skin barrier in patients with psoriasis vulgaris. This research method is a randomized, single-blind, pre and posttest design controlled trial involving patients with mild/moderate/severe psoriasis vulgaris at DR. Kariadi Hospital Semarang, Indonesia. The subjects of the study were divided into 2 groups, namely 1% colloidal oatmeal and 100% petrolatum. Evaluation was carried out by comparing the TEWL values between day 0 and day 28. The analysis was carried out using independent T-tests, Mann Whitney, and Wilcoxon. The results were significant if p<0.05 Results Topical administration of 1% colloidal oatmeal or 100% petrolatum could lower the TEWL value in each study group (p<0.001; p=0.006 respectively). ΔTEWL evaluation showed a significantly greater decrease in TEWL in the 1% colloidal oatmeal group (p=0.003). No complaints during use were reported in the 1% colloidal oatmeal group. Conclusion: Topical application of 1% colloidal oatmeal is more effective than 100% petrolatum as a moisturizer in improving the skin barrier in patients with psoriasis vulgaris without complaints.

Effectiveness of topical combination of finasterid and minoxidil in the management of male androgenetic alopesia (systematic review and meta-analysis: Hair density study) Riyanto, Puguh; Karami, Muhammad Zuldan; Malik, Diah Adriani
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2119

Androgenetic alopecia (AAG) is the most common hair loss problem in men, characterized by miniaturization of hair follicles due to systemic androgens and genetic factors. AAG treatment aims to prevent follicle miniaturization Treatment modalities for AAG include hair transplantation, platelet-rich plasma (PRP), microneedling, and stem cells. Each treatment modality has its benefits and risks. The combination of topical finasteride and topical minoxidil has been shown to improve outcomes in several studies. This study aimed to evaluate the efficacy of topical finasteride compared to topical minoxidil in improving hair density among male AAG patients. A systematic literature search method was conducted using MEDLINE, Embase, AMED, Cochrane Library, Clinicaltrials.gov, Web of Knowledge, Web of Science, and WHO ICTRP with the search terms "topical finasteride and minoxidil" 'AND' "male androgenetic alopecia" 'AND' "male pattern hair loss". The literature search was carried out in accordance with the PRISMA 2009 path. Three RCTs were included in the qualitative synthesis and included in the meta-analysis. The results showed that the overall SMD in hair density was 0.751±0.215 (95% CI: 0.331 – 1.162, p<0.001) in favor of topical finasteride and topical minoxidil combination treatment, suggesting that topical finasteride and topical minoxidil combination had much greater effectiveness than control treatments in improving hair density among male patients with AAG.

Co-Authors Aghnila Fasza Gita Tsuraya Alexander, Lim Almira Dwixie Dhara Desira Anastasia Piramitha Angela Soesanto Aryoko Widodo Aryoko Widodo, Yulian Ludovicus Asih Budiastuti Asih Budiastuti Bambang Witjahyo Cagar Irwin Taufan Pamungkas Cindy Cindy Cindy Cindy Damayanti, Galih Sari Danisa Diandra Safarina Danisa Diandra Safarina Dea Amarilisa Adespin Devina Adiyani Pranowo Devina Subagio Devy Kurniawati Dhega Anindita Wibowo Dhega Anindita Wibowo, Dhega Anindita Diah Adriani Malik Dini Hisan Wijdani Dini Hisan Wijdani Dwi Murtono Dyah Ayu Kusumaningrum Felicia Yora Afrilia Putri Fernandes, Albert Hani Nur Rahmawati Purwanto Hidayati, Noufry Zaliva Karami, Muhammad Zuldan Koncara, Fatan Khalif Leoni Agnes Liza Afriliana Lydia Eryana Triastuti Lydia Eryana Triastuti Mejestha Rouli Puspitasari Murtono, Dwi Myrna Adiwijaya Nurmaliannysa Dwinandia Harahap Nurul Nisa Ulfa Olivia Jovina Olivia Jovina Priyanto Olivia Jovina Priyanto Pho Denita Meiliani Priskila Dwi Kurniasih Retno Indar Widayati Rima Adjani Rima Adjani Nugroho Sari Satya Febriani Sari Satya Febriani Subagio, Devina Sugianto, Yosep Ferdinand Rahmat Widyawati Widyawati Widyawati Widyawati Wikanta, Edmond Rukmana Yulian Ludovicus Aryoko Widodo Z, Mutia Dian Permatasari Mochtar Zahroh Shaluhiyah

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