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Efektifitas Rebusan Daun Babadotan dan Kombinasinya dengan Pregabalin sebagai Anti Nyeri Neuropatik serta Uji Toksisitas Akutnya Yedy Purwandi Sukmawan; Hendy Suhendy; Maritsa Nurfatwa
JURNAL ILMU KEFARMASIAN INDONESIA Vol 19 No 2 (2021): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v19i2.1057

Abstract

Neuropathic pain is a condition that is difficult to treated and impaired quality of life. The objective of the study was to determine the anti-neuropathic pain effectivity of Ageratum conyzoides aqueous extract and the acute toxicity study. We had 7 groups (normal, negative, pregabalin, ageratum. conyzoides-I (AC-I) 50mg/kg BW, A. conyzoides-II (AC-II) 100mg/kg BW, combination of pregabalin and AC-II), combination of AC-II and naloxone). Each group contain 5 animals (mice). All groups was induced with pyridoxine 400 mg/kg BW i.p for 14 days to cause neuropathy and followed by hyperalgesia, allodynia, and wire-hang test. In the acute toxicity study, we had 1 group and contain 5 animals (rats). The results of the hyperalgesia and allodynia study showed the effect of AC-II was better than AC-I. The combination of pregabalin and AC-II was better than AC-II as monotherapy (p<0.05). However, AC II activity was abolished when combined with naloxone. In wire hang test demonstrated no difference between falling score (p: 0.053) and reaching score (0.903), that showed AC-II wasn’t impaired the motoric system. No death or toxicity symptoms were observed for 14 days in the acute toxicity study. A. conyzoides aqueous extract is potential for anti-neuropathic pain..
Penyuluhan Covid-19 dan Workshop Pembuatan Hand Sanitizer di Pondok Pesantren Suryalaya Tasikmalaya Ruswanto Ruswanto; Saeful Amin; Anna Yuliana; Tita Nofianti; Nur Rahayuningsih; Ira Rahmiyani; Tresna Lestari; Diana Sri Zustika; Ilham Alifiar; Hendy Suhendy; Mochamad Fathurahman; Anindita Tri Kusuma Pratita; Vera Nurviana; Annisa Pebiansyah; Muharam Priatna
J-ABDIPAMAS (Jurnal Pengabdian Kepada Masyarakat) Vol 5, No 1 (2021): APRIL 2021
Publisher : IKIP PGRI Bojonegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (532.092 KB) | DOI: 10.30734/j-abdipamas.v5i1.1115

Abstract

Coronavirus atau virus corona merupakan keluarga besar virus yang menyebabkan infeksi saluran pernapasan atas ringan hingga sedang, seperti penyakit flu. Salah satu peran yang dapat disumbangkan oleh Perguruan Tinggi dalam pencegahan dan penanganan covid-19 adalah meningkatkan pengetahuan dan pemahaman masyarakat tentang seluk beluk yang ada hubungan covid-19 dan penangannya melalui pengabdian masyarakat. Metode yang digunakan dalam pengabdian masyarakat yang dilakukan adalah ceramah/ diskusi, perencanaan partisipatif dan praktek. Dari hasil pengabdian masyarakat yang dilakukan menjukkan bahwa masyarakat sangat bersemangat dan aktif diskusi dalam mengikuti penyuluhan tentang covid-19 dan cara pembuatan hand sanitizer.
Comparison of Fig Juice Fruitghurt with Variations in Sucrose and Length of Fermentation Anna Yuliana; Zalfa Zahira Fauziah; Hendy Suhendy
JURNAL SAINS NATURAL Vol. 13 No. 4 (2023): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31938/jsn.v13i4.597

Abstract

Fruitghurt is a fermented product made from fruit juice and milk, which is an important food source of protein to meet nutritional needs. Therefore, researchers added figs containing glucose, fructose, dietary fiber, and antibacterial properties to get the best fruit yoghurt. This study aims to determine the effect of sucrose concentration and the length of fermentation time for fig juice fruitghurt using Lactobacillus bulgaricus and Streptococcus thermophilus starters and to determine the antibacterial activity of fruit juice and fruitghurt through testing against Escherichia coli. Concentration was 0, 14, and 18%, and fermentation was carried out for 0, 18, and 24 hours, The parameters of this research were based on microbiological, chemical, and physical properties. The research showed that sucrose concentration and fermentation time affected Lactic Acid Bacteria (LAB), pH, , pH decreased from 4.5 to 4.0Total Titrated Acid (TAT), viscosity, total dissolved solids, color, aroma, texture, and taste. Total BAL had the highest value of  CFU/mL, and TAT increased from 0.50% to 0.65%. The viscosity with the highest value is 12.33 cP. Total dissolved solids decreased from 13% to 11%. All parameters meet the requirements of SNI 2981:2009. The antibacterial activity test showed an inhibition zone with a value of 7.4 mm. The average value of the researcher's preference for color, taste, and aroma in the 0-hour formula with 0% sucrose, the 24-hour formula with 14% sucrose, and the 24-hour formula with 18% sucrose. The best fermentation time and sucrose concentration was 24 hours and 18% sucrose.