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All Journal Journal of Economic, Bussines and Accounting (COSTING) Indonesian Journal of Chemistry Jurnal Ilmiah Kesehatan Jurnal Ilmu Kefarmasian Indonesia Jurnal Ilmiah Farmako Bahari Enrichment : Journal of Management International Journal of Science and Society (IJSOC) Jurnal Farmasi Indonesia
Faizatun
Universitas Pancasila
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Formulasi Gel NLC Ekstrak Kalus Daun Murbei Hasil Induksi dengan NAA dan BAP Faizatun Faizatun; Erlindha Gangga; Sarah Anindita; Titiek Martati; Nur Miftahurrohmah
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 1 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (465.936 KB) | DOI: 10.35814/jifi.v18i1.814

Abstract

Mulberry Leaf (Morus alba L.) contains oxyresveratrol has the potential as a skin lightener. The activity of mulberry leaf callus from tissue culture is unknown as an inhibitor of the tyrosinase enzyme. The purpose of this study was to determine the activity callus extracts of mulberry leaf which obtained from tissue culture with the addition of growth regulator NAA 1.0 ppm and BAP 2.5 ppm and to formulate callus extract in Nanostructured Lipid Carrier and its characteristics. Callus was extracted by maceration-sonication. NLC is made by solvent evaporation method, NLC characterization including particle size, polydispersity index, zeta potential and particle morphology. The best NLC was made into a gel and evaluated organoleptic, viscosity, flow properties, pH, and tyrosinase enzyme inhibitory on extracts and NLC gels. The characterization of NLC includes particle size of 189.8 nm-632.8 nm; polydispersity index, 0.387-0.582. The morphology of NLC were spherical and zeta potential of -7.37 mV. NLC gel was semi-solid, greenish yellow, homogeneous, viscosity 530000 cPs, plastic thixotropic flow properties, pH 5.26, and inhibitory activity of tyrosinase enzymes (IC50) of callus extract and NLC gel has 72.51 µg/ml and 79.69 µg/ml, respectively. It can be concluded that callus extract of Mulberry leaf can be prepared into Nanostructured Lipid Carriers, NLC gels are physically and chemically stable and have the potential of lightening activity.
Formulasi Tablet Matriks Mukoadhesif Diltiazem Hidroklorida Menggunakan Hidroksi Propil Metil Selulosa dan Carbopol 940 Siti Sofiah; Faizatun Faizatun; Yulia Riyana
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1468.394 KB)

Abstract

Diltiazem hydrochloride has a half life of 3-4 hours and a bioavailability of 40%. The influence of a mixture of carbopol 940 and hydroxypropyl methyl cellulose as a mucoadhesive matrix on tablets made by the wet granulation method, had been determined by the dissolution and “wash off method. The result showed that increasing the concentration of carbopol 940 decreased the dissolution rate. The concentration of carbopol 940 and hydroxypropyl methyl cellulose in formula I (0%; 40%), II (5%; 35%), III (10%; 30%), IV (15%; 25%), and V (20%; 20%) released respectively 75,99%; 74,08%; 73,07%; 72,04%; and 71,29% diltiazem hydrochloride. The higher the concentration of carbopol 940 in acid solution, the shorter is the mucoadhesive action: 2 hours in formula I and II, and 1 hour in formula III, IV, and V. All of the formulas (pH 7,2) did not show a difference in mucoadhesive duration; after 8 hours, still attached to the mucosa of the small intestines.
Formulasi Sediaan Sampo Ekstrak Bunga Chamomile dengan Hidroksi Propil Metil Selulosa sebagai Pengental FAIZATUN FAIZATUN; KARTININGSIH KARTININGSIH; LILYANA LILIYANA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 6 No 1 (2008): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Chamomile (Chamomilla recucita L.) that contain apigenin as an active substance are known as hair-lightening agent. The application of these flowers as such is not convenient, so the incorporation of its extract in shampoos - for cleaning of both scalp and hair - gives a better outcome. In this study, six formulas Were applied, each containing 5% of chamomile extract with different concentrations of HPMC (Methocel® F4M) and other additives. The shampoos were evaluated during a six Week-storage on their physico-chemical properties (pH, viscosity, rheological characteristic at 28-30°C [room temperaturel, 40°C, and 6-7°C [chilled temperature], surface tension, foam-forming in hard and distilled water as Well as sensory properties [discoloration, odor, homo genenity]. The results showed that HPMC of 2% gave an optimum viscosity, no discoloration, no detected change on homogenenity as Well as odor until the end of six-Week storage. The viscosity the shampoo with 2% HPMC at 28-30°C was 2060.00-2080.00 cPs,at 40°C 1040.00-1080.00 cPs, and at 6-7°C 2420.00-2480.00 cPs. Having rheological characteristic of pseudoplastic, the shampoo’s surface tension Was 28.99-29.88 dyne/cin, with density ranged 1,0428- 1.0459, pH 6.26-6.34, height of foam in hard Water ranged 3.30-3.45 cm and in distilled 3.40-3.60 cm. The density, surface tension, and pH of the shampoo were in agreement with the requirements. Key words: Hydroxypropyl methyl cellulose, chamomile, shampoo, viscosity.
Formulation of Blush Preparations by Using Natural Coloring from Red Beetroot Extract (Beta vulgaris L.) Suci Wulan Sari; Ratna Djamil; Faizatun Faizatun
Indonesian Journal of Chemistry Vol 21, No 4 (2021)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.60414

Abstract

Beetroot (Beta vulgaris L.) has compounds that can be used for body health, beauty skincare, food additives, and much more. This research was aimed to prepare the dry extract of beetroot and formulate it into a loose powder, compact powder, and cream. The preparation was started by adding 2, 4, or 6% of dry extract, then blending the pulp and drying the resultant residue using a freeze dryer. Testing on color homogeneity, polishing, breakage, pH stability, color stability, and the hedonic test was carried out to determine the product quality. The initial result of phytochemical screening showed it might contain flavonoids, alkaloids, saponins, tannins, triterpenoids, steroids, and quinones. The color stability test performed at 30 °C showed that the cream was unstable while other forms showed fair stability at 8 °C. All dosage forms were homogeneous and could be applied easily. The breakage test showed no fractures. The pH remained stable for all formulas (between 3–5) after 28 days of storage. The color stability test showed that the significant discoloration only happened to the loose powder and cream. The hedonic test showed that the compact powder with a concentration of 6% was the most preferred formula by users.
Pengembangan Krim Ekstrak Dedak Padi (Rice Bran) dan Susu Kuda Sumbawa sebagai Antihiperpigmentasi Muh Taufiqurrahman; Faizatun Faizatun; Siswa Setyahadi
Jurnal Ilmiah Kesehatan Vol 20 No 3 (2021): Jurnal Ilmiah Kesehatan terbitan Desember Volume 20 Nomor 03 Tahun 2021
Publisher : STIKIM Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikes.v20i3.1462

Abstract

Antihiperpigmentasi pada produk kosmetik (hidrokionon) memiliki efek samping yang membahayakan kulit apabila digunakan dalam tempo waktu yang lama. Alternatif lain antihiperpigmentasi dari bahan alam berupa dedak padi dan susu kuda Sumbawa disinyalir dapat berpotensi sebagai antihiperpigmentasi yang aman dan memiliki efektivitas yang lebih baik untuk kesehatan kulit jangka panjang. Penelitian ini bertujuan untuk mengembangkan krim ekstrak dedak padi dan susu kuda Sumbawa sebagai krim antihiperpigmentasi yang aman terhadap kulit. Uji standarisasi pada dedak padi dan susu kuda Sumbawa dilakukan sesuai dengan regulasi standard dari kementerian kesehatan. Uji antihiperpigmentasi dilakukan dengan secara eksperimental secara in vitro pada penghambatan (% inhibisi) enzim tironase. Pengembangan krim formulasi dedak padi dan susu kuda Sumbawa dilakukan uji inhibisi dan uji keamanan melalui indeks iritasi pada kelinci. Standarisasi ekstrak dedak padi menunjukkan ekstrak tersebut memenuhi persyaratan mutu yang baik (cemaran logam negatif ) dan hasil yang sama pada susu kuda Sumbawa (total coliform memenuhi standard). Hasil kombinasi antara ekstrak dedak padi dan susu Sumbawa menunjukkan inhibisi yang lemah sebesar 224,01 μg/mL. Uji keamanan krim kombinasi pada kelinci mendapatkan hasil indeks iritan 0,11 yang termaksud kategori aman bagi kulit. Pengembangan krim dari kombinasi ekstrak dedak padi dan susu kuda Sumbawa terbukti efektif dan aman sebagai antihiperpigmentasi.
EVALUASI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL HERBA SURUHAN (PEPEROMIA PELLUCIDA L.), HERBA SELEDRI (APIUM GRAVEOLENS L.) DAN KOMBINASI EKSTRAK: STUDI IN VIVO BERBASIS BUKTI ILMIAH Yogi Rahman Nugraha; Dani Sujana; Yunahara Farida; Faizatun Faizatun
Jurnal Ilmiah Farmako Bahari Vol 13, No 1 (2022): Jurnal Ilmiah Farmako Bahari
Publisher : Fakultas MIPA Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jfb.v13i1.1312

Abstract

Hiperurisemia adalah suatu kondisi dimana kadar asam urat meningkat. Hiperurisemia disebabkan oleh kelainan genetik pada sistem metabolisme tubuh yang mencegah tubuh mengeluarkan asam urat dari tubuh. Flavonoid dan alkaloid merupakan senyawa yang dipercaya mampu menurunkan kadar asam urat dalam darah dengan cara menghambat kerja xantin oksidase dan superoksidase. Herba suruhan dan seledri telah lama dipakai sebagai obat tradisional untuk mengatasi keluhan asam urat. Pada penelitian ini dilaporkan bahwa ekstrak etanol seledri dan herba seledri serta ekstrak gabungan menunjukkan aktivitas antihiperurisemia yang signifikan terhadap kontrol negatif selama pengamatan (p<0,05). Dosis 250 mg/kgBB menunjukkan aktivitas paling baik (kombinasi ekstrak etanol herba suruhan (Peperomia pellucida 75%) ekstrak etanol herba seledri (Apium graveolens 25%) dengan penurunan asam urat sebesar 58,4%.
Pengaruh pengisi hasil Spray Drying terhadap karakteristik Orally Disintegrating Tablet (ODT) Famotidin Faizatun Faizatun; Andreas Agung Saputra; Safira Nafisa
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 11 No. 2 (2019): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5294.663 KB) | DOI: 10.35617/jfionline.v11i2.2

Abstract

Famotidin digunakan dalam pengobatan penyakit lambung dan diperlukan waktu kerja obat yang cepat dalam penggunaan. Orally Disintegrating Tablet (ODT) merupakan suatu sediaan yang memiliki waktu hancur yang cepat, sehingga efek terapi dari famotidin dapat terjadi dengan segera. Pada penelitian ini, dilakukan perbandingan karakteristik ODT dengan pengisi ODT yang dibuat dengan metode spray drying dan pengisi pembanding yang terdapat dipasaran. Pengisi ODT yang dibuat terdiri dari avicel PH 102, xylitol, manitol, dan crospovidone ( 2; 3,5; 5%). Pengisi ODT yang dihasilkan digunakan untuk pembuatan tablet ODT secara cetak langsung. Evaluasi pengisi berupa uji sifat alir, kadar air, dan kompresibilitas, sedangkan evaluasi tablet ODT terdiri dari uji waktu hancur, disolusi, kekerasan, dan friabilitas untuk melihat pengaruh perbedaan konsentrasi crospovidone yang digunakan terhadap kecepatan hancurnya ODT. Hasil penelitian menunjukkan  F III dengan konsentrasi crospovidone 5% dari tablet, memiliki waktu hancur lebih cepat (44,45 detik), kekerasan yang lebih kecil (5,68 kg/cm2) dan friabilitas yang besar (0,435%) dibandingkan tablet F I dan F II. Tablet F III memiliki waktu hancur yang lebih lama (44,45 detik) dari tablet ODT pembanding (33 detik).
The impact of social media marketing on instagram for cosmetic brands in Indonesia Tedi Rustandi; Faizatun Faizatun; Derriawan Derriawan
Enrichment : Journal of Management Vol. 13 No. 4 (2023): October: Management Science And Field
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/enrichment.v13i4.1638

Abstract

Opportunities and challenges in several aspects of Indonesia, such as the number of cosmetic companies by 78.34% (2021), the increase in the GDP of the cosmetics sector by 9.61% (2021), the increase in registered cosmetic products by 53.65% (2022), and the low level of purchase return of cosmetic products increased competition between cosmetic brands in Indonesia. This study analyzes the impact of social media marketing for the Wardah, Revlon, and Pixy brands on Instagram on brand image, brand awareness, purchase decision, and repurchase intention. Data was collected through a survey using the convenience technique of 175 respondents who were followers of the Wardah, Revlon, and Pixy brands. Data analysis used the Partial Least Squares Structural Equation Modeling (PLS-SEM) method. Social media marketing research results affect brand awareness and brand image and do not affect purchase decision and repurchase intention. Brand awareness affects brand image, purchase decision, and repurchase intention. Brand image does not influence purchase decision and repurchase intention. Purchase decisions affect repurchase intentions.This research provides insight into the application of social media marketing in Indonesia on the Instagram platform, which has a complex relationship with brand awareness, brand image, purchase decision, and repurchase intention
Formulasi Gel Nanostructured Lipid Carriers Ekstrak Akar Murbei (Morus alba L.) sebagai Pencerah Kulit pada Model Zebrafish Faizatun Faizatun; Irene Intan Permata Murti
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1473

Abstract

Mulberry is a plant that has been shown to be effective as a whitening agent. The objective of this research was to evaluate the efficacy of mulberry root extract (MRE) and its nanostructured lipid carrier (NLC) extracts in terms of their ability to lighten skin tone by using zebrafish as a model. NLC were formulated into gel preparations. The whitening effect of MRE and NLC was evaluated, and the melanin content of the extracts was found to be the result of the evaluation. Based on the results of morphological observations, a decrease in melanin levels was seen in the eye. In the mulberry root extract, the melanin level decreased with an increase in the concentration of the mulberry root extract. In the NLC of mulberry root extract, a decrease in melanin levels was obtained at an increased NLC concentration of mulberry root extract. It can be concluded that mulberry root NLC has the ability to act as a whitening agent, which is distinguished by the reduction of melanin content.
Analysis of the Influence of Brand Association, Brand Image, Brand Awareness, and Brand Loyalty on Brand Equity of Telon Oil Rony Indrayana; Faizatun; Derriawan
International Journal of Science and Society Vol 6 No 2 (2024): International Journal of Science and Society (IJSOC)
Publisher : GoAcademica Research & Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54783/ijsoc.v6i2.1121

Abstract

This research aims to analyze the influence of brand association, brand image, brand awareness, and brand loyalty on brand equity of telon oil. This research uses a quantitative approach with the sample in the study being women or men aged 25 – 55 years and who have used My Baby telon oil. In carrying out this research, researchers used data analysis methods using the Likert scale measurement method, questionnaire data analysis using the SPSS 26 statistical program with the SEM SmartPLS method. The research results show several important findings regarding the relationship between the main variables in the context of Brand Equity. First, Brand Association (X1) significantly influences Brand Equity (Z) and Brand Loyalty (Y). Second, Brand Awareness (X2) has a significant influence on Brand Loyalty (Y), but not on Brand Equity (Z). Third, Brand Image (X3) significantly influences Brand Equity (Z), but not significantly on Brand Loyalty (Y). Apart from that, Brand Loyalty (Y) was also found to have a significant influence on Brand Equity (Z). These findings provide important insights for marketing and brand management strategies to strengthen key aspects that influence consumer perception and loyalty towards brands.
Co-Authors Dani Sujana Derriawan Derriawan Derriawan Erlindha Gangga Iha Haryani Hatta Irene Intan Permata Murti Kartiningsih Kartiningsih Lila Quraisyin Taslim LILYANA LILIYANA Martati, Titiek Miftahurrohmah, Nur Ratna Djamil Rony Indrayana RR. Ella Evrita Hestiandari Rustandi, Tedi Safira Nafisa Sarah Anindita Siswa Setyahadi Siti Sofiah Suci Wulan Sari Taufiqurrahman, Muh Yogi Rahman Nugraha Yulia Riyana Yunahara Farida