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All Journal HAYATI Journal of Biosciences JCPS (Journal of Current Pharmaceutical Sciences) JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT
Atmira Sariwati
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Agriculture, Biological Sciences & Forestry Humanities Earth & Planetary Sciences Environmental Science Library & Information Science Medicine & Pharmacology Nursing Public Health Veterinary Other

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IDENTIFIKASI SENYAWA KIMIA DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETIL ASETAT BIJI SIRSAK (Annona mucicata Linn.) Anindini Winda Amalia; Atmira Sariwati
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 1 (2019): September 2019
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Antioxidants are substances that are useful for fighting free radicals. Plants can produce antioxidants to control the oxidative stress.Soursop plants are one of the plants that are known to contain antioxidant flavonoids. The purpose of this study was to determine the content of chemical compounds and antioxidant activity of ethyl acetate extract of soursop seeds. Identification of the content of chemical compounds was carried out qualitatively and quantitatively, while the antioxidant test was carried out using the capture method of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals with ascorbic acid as a comparison. The results showed that the soursop seeds ethyl acetate extract contained flavonoids, alkaloids, and saponins, while the results of the quantitative total phenolic and total flavonoid tests were 28.21 ± 0.03 mg/g and 22.17 ± 0.05 mg/g respectively. DPPH results of soursop seeds ethyl acetate extract were 39.45%. These results show that the soursop ethyl acetate extract has a weak antioxidant activity compared to gallic acid. Keywords: soursop seed extract, chemical identification, antioxidants, ethyl acetate, DPPH
Pengolahan Pangan Fungsional Berbasis Pangan Lokal Oktovina Rizky Indrasari; Yoanita Indra Kumala Dewi; Nining Tyas Triatmaja; Mohamad Anis Fahmi; Forman Novrindo Sidjabat; Atmira Sariwati; Ekawati Sutikno; Dianti Ias Oktaviasari; Ana Nur Filiya
Journal of Community Engagement and Empowerment Vol 4, No 1 (2022)
Publisher : Institut Ilmu Kesehatah Bhakti Wiyata Kediri

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Latar Belakang: Tempe merupakan pangan fungsional dengan harga terjangkau yang banyak dikonsumsi sebagai protein nabati. Tempe kedelai lebih dikenal dan disukai oleh banyak orang karena warnanya yang putih dan tekstur yang kompak sehingga lebih menarik untuk dikonsumsi. Oleh karena itu, perlu adanya upaya meningkatkan pengetahuan dan kesadaran terkait pangan fungsional berbasis pangan lokal tempe. Upaya peningkatan pengetahuan dan kesadaran masyarakat dapat dilakukan dengan melibatkan peran serta remaja sebagai kader muda sadar kesehatan. Tujuan Kegiatan: meningkatkan pengetahuan, pemamaham dan kemampuan peserta dalam mengedukasi pengolahan pangan fungsional berbasis pangan lokal tempe.Metode Kegiatan: Bentuk kegiatan yang dilakukan dalam kegiatan pengabdian masyarakat, yaitu  penyuluhan meningkatkan pengetahuan, pemamaham dan kemampuan peserta dalam mengedukasi pengolahan pangan fungsional berbasis pangan lokal tempe. Kegiatan ini dilakukan secara daring dengan jumlah peserta sebanyak 47 peserta. Hasil Pengabdian: Rata-rata pengetahuan peserta terkait pengolahan pangan lokal tempe sebelum dilakukannya edukasi adalah 3,78  dan mengalami peningkatan setelah diedukasi, yaitu 4,76. Simpulan dan Saran: Pelatihan daring terkait pengolahan pangan fungsional berbasis pangan lokal tempe dapat meningkatkan pengetahuan peserta. Saran yang dapat diberikan adalah sebaiknya dilakukan metode lain dalam edukasi dengan menggunakan media yang berbeda.
Antioxidant, Antidiabetic, and Antibacterial Activities of Terminalia bellerica Seed Extracts in Various Solvent Polarities Atmira Sariwati; Fita Sari; Venty Suryanti; Desi Suci Handayani; Ichiro Kamei; Ninis Yuliati
HAYATI Journal of Biosciences Vol. 31 No. 5 (2024): September 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.5.854-866

Abstract

Terminalia bellerica is well-known for producing edible fruits with pharmacotherapeutic properties. Traditional healers use these species to treat and control diabetes mellitus, its side effects, and other illnesses. Involved in this disease's pathophysiological process, extensive research has been conducted to validate and comprehend these bioactive claims scientifically. This research aims to ascertain the bioactive metabolite contents of different solvent polarities, including ethyl acetate, hexane, distilled water, and methanol. The phenol concentration was determined using the Follin-Ciocalteu procedure to be between 23.45 and 160.41 mg GAE/g. The aluminum chloride colorimetric technique measured flavonoid concentration from 88.52 to 7.12 mg QE/g. The quantitative values of tannic acid, which spanned from 0.78 to 5.32 mg TAE/g, were determined by spectrophotometry UV-VIS. The extracts' capacity to reduce free radical damage ABTS (2, 2' azinobis (3-ethylbenzene-thiazoline-6-sulfonic-acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) was examined. The extract ethyl acetate exhibited the most significant level of antioxidant activity, with IC50 values for DPPH and ABTS of 28.17 and 22.22 g/ml, respectively. Staphylococcus aureus (23 mm) and were tested for antibacterial and antifungal activity in a methanol extract (21 mm). In vitro, antidiabetic activities were assessed using α-glucoside and α-amylase inhibition. The ethyl acetate extract has α-glucoside inhibition IC50 of 23.04 g/ml and α-amylase inhibition IC50 of 25.35 g/ml. T. bellerica seed includes secondary metabolites that show promise as lead chemicals in creating potent medications.
Co-Authors Ana Nur Filiya Anindini Winda Amalia Desi Suci Handayani Dianti Ias Oktaviasari Ekawati Sutikno Fita Sari Ichiro Kamei Mohamad Anis Fahmi Nining Tyas Triatmaja Ninis Yuliati Oktovina Rizky Indrasari Sidjabat, Forman Novrindo Venty Suryanti Yoanita Indra Kumala Dewi