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Hubungan Kepatuhan Terapi Kelasi Dengan Kadar Feritin Serum Pada Pasien Thalasemia B Mayorpada Anak Di Rsam Provinsi Lampung Zulhafis Mandala; Festy Lady; Muhammad Fahrin Ramadhan
MAHESA : Malahayati Health Student Journal Volume 1 Nomor 2 Juni 2021
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.255 KB) | DOI: 10.33024/mahesa.v1i2.3774

Abstract

ABSTRACT: RELATIONSHIP OF COMPLIANCE WITH KELSI THERAPY WITH SERUM FERITIN LEVELS IN THALASSEMIA β MAYOR PATIENTS IN CHILDREN AT BANDAR LAMPUNG HOSPITAL Background: Thalassemia is a heterogeneous group of hereditary anemia caused by mutations in hemoglobin synthesis (Cunningham et al., 2009). In the world, thalassemia annually reaches 1 in 100,000 people. The incidence of thalassemia in the world is based on data from the World Health Organization or the World Health OrganizationPurpose To determine the relationship between chelation therapy provision and serum ferritin levels in Thalassemia B Mayor patients in Dr. Hi Abdul Moeloek, Lampung Province in 2019.Aim: To find out the relationship between the adherence to iron therapy with serum ferritin levels at RSAM in 2019.Methods: This research is quantitative with the observational analytic method with a cross-sectional approach. The total population was 115 patients. A sample of 60 patients thalassemia β mayor. This research was conducted from Feb 2020 to completion. Analysis through univariate analysis.Results: the relationship of compliance with kelasi therapy with serum feritin levels in thalasemia β mayor patients at rsam hospital 2019, 34 respondents who obeyed chelation therapy, as many as 21 respondents (61.8%) had no risk ferritin levels (≤1000), of the 36 respondents who did not comply with chelation therapy, as many as 6 respondents (23.1%) had levels ferritin No Risk (≤1000) The results of the analysis also obtained an OR value of 5.38 (95% CI 1.7-16.9), which means that respondents who are adherent to iron therapy are at risk of having ferritin levels at risk (≥ = 1000) 5.38 times greater than who do not adhere to iron therapy.Conclusion: It is known that there is a relationship between adherence to iron therapy and serum ferritin levels at rsam hospital in 2019. Keywords: Thalassemia, Iron Therapy, Ferritin LevelsINTISARI: HUBUNGAN KEPATUHAN TERAPI KELASI DENGAN KADAR FERITIN SERUM PADA PASIEN THALASEMIA β MAYOR PADA ANAK DI RSAM BANDAR LAMPUNG  Latar Belakang : Thalasemia merupakan salah satu kelompok heterogen anemia herediter yang disebabkan oleh mutasi pada sintesis hemoglobin (Cunningham et al., 2009). Di dunia, insiden thalasemia setiap tahunnya diperkirakan mencapai 1 dari 100.000 orang. Angka kejadian penyakit thalasemia di dunia berdasarkan data  dari Badan Organisasi Kesehatan Dunia atau World Health OrganizationTujuan Mengetahui hubungan kepatuhan terapi kelasi dengan kadar feritin serum pada pasien Thalasemia B Mayor Di RSUD Dr. Hi Abdul Moeloek Provinsi Lampung Tahun 2019Metode Penelitian : Penelitian ini adalah kuantitatif dengan metode analitik observasional dengan pendekatan cross sectional. Jumlah populasi 115 pasien. Sampel 60 pasien dengan diagnosis thalassemia β mayor. Peneltian ini dilakukan pada bulan februari 2020 sampai dengan selesai. Analisa melalui analisa bivariat.    Hasil : hubungan kepatuhan terapi kelasi dengan kadar ferritin serum pada pasien thalsemia β mayor di RSAM bandar lampung tahun 2019 34 responden yang patuh dalam terhadap terapi kelasi, sebanyak 21 responden (61,8%) memiliki kadar ferritin Tidak Beresiko (≤1000), dari 36 responden yang tidak patuh dalam terhadap terapi kelasi, sebanyak 6 responden (23,1%) memiliki kadar ferritin Tidak Beresiko (≤1000. Hasil analisis diperoleh pula nilai OR 5,38 (95% CI 1,7-16,9) yang berarti bahwa responden yang patuh dalam terhadap terapi kelasi, berisiko memiliki kadar feritin beresiko (≥=1000) 5,38 kali lebih besar dibandingkan dengan yang tidak patuh dalam terhadap terapi kelasi.Kesimpulan : Diketahui terdapat hubungan kepatuhan terapi kelasi dengan kadar ferritin serum di RSAM Bandar Lampung tahun 2020 Kata kunci     :  Thalasemia, Terapi Kelasi, Feritin Serum
Nilai Indeks Shine dan LAL antara Anemia Defisiensi Besi dengan Thalassemia di RSUD Dr. H. Abdul Moeloek Syuhada Syuhada; Zulhafis Mandala; Astri Pinilih; Dwita Canggi Siregar
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 1 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v11i1.235

Abstract

Background: Iron deficiency anemia and β minor thalassemia have the same morphological picture of hypochromic blood, therefore it needs to be distinguished from an examination. The diagnosis of β-thalassemia minor and iron deficiency anemia can be made by conducting a series of screening laboratory tests, ranging from the routine hematological examination, peripheral blood smear preparations, staining of peripheral blood smear preparations with supravital staining for reticulocyte counts and detection of HbH inclusion objects in erythrocytes, reserve status iron blood with a groove examination in stages until a sophisticated examination that is Hb electrophoresis and DNA examination. Objective: To find out the comparison of the shine & lal index between iron deficiency anemia patients and thalassemia patients in Dr. H. Abdul Moeloek Lampung Province. Method: This type of research is a comparative test. With the number of samples using a ratio of 1: 1 so that 45 people with iron deficiency anemia and 45 people with thalassemia found in Dr. H. Abdul Moeloek Lampung Province. Results: The Mann-Whitney test results showed a sig value of 0.029. Then H1 is accepted because of the value of sig <0.05. Conclusion: There is a significant difference in the value of the shine & lal index between iron deficiency anemia patients and thalassemia patients in Dr. H. Abdul Moeloek Lampung Province
Kadar Ferritin dengan Status Gizi Pasien Thalassemia β Mayor Anak di RSAM Bandar Lampung Rita Agustina; Zulhafis Mandala; Rewina Liyola
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 1 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v11i1.252

Abstract

Thalassemia is a disease of hemolytic anemia characterized by abnormalities in globin chain synthesis. Continuous transfusion in patients with thalassemia can cause iron buildup or accumulation of iron so that ferritin levels increase in the body, especially in the liver, heart, and endocrine organs. Problems in the endocrine glands and the condition of anemia can interfere with the growth of children, causing a decrease in appetite and cause a lack of nutrition into the body. The purpose of the research is to know the correlation between ferritin levels with nutritional status in Thalassemia patients β Major children. This research uses an analytic observational method with a cross-sectional approach. The subjects in the study were 60 patients. The instrument used was medical record data. The results of statistical analysis using the Chi-Square test showed a p-value of 0.02 (p-value <0.05) which means that there is a relationship between ferritin levels and nutritional status in Thalassemia patients β Major children in Abdul Moeloek Hospital, Bandar Lampung Year 2019. There is a correlation between ferritin levels with nutritional status in patients with Thalassemia β Major children at Abdul Moeloek Hospital in Bandar Lampung in 2019.
Hubungan Kadar Feritin Serum dengan Kadar Enzim SGOT dan SGPT pada Pasien Thalasemia β Mayor Rita Agustina; Zulhafis Mandala; Ressy Nirmala Indah
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 1 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v11i1.258

Abstract

Thalassemia is a genetic blood disorder that can cause hemolysis in hemoglobin. So the patient must get a transfusion for life. The transfusion is done continuously, this is what causes patients with thalassemia β major to have iron buildup in their body. So the levels of Ferritin, SGOT, and SGPT enzymes can be increased in patients with β major thalassemia. This study aims to determine the relationship between serum ferritin with SGOT and SGPT enzymes in thalassemia β major patients. This research uses an analytic method with a cross-sectional approach. The subjects in this study were 60 samples. The instrument used was the patient's medical record data. Statistical analysis using the Chi-Square test showed a p-value 0.005 (p-value <0.05) for serum ferritin with SGOT. And for serum ferritin with SGPT enzymes, p-value 0.004 (p-value <0.05), it means that there is a relationship between serum ferritin and SGOT and SGPT enzymes. There is a correlation between serum ferritin with SGOT and SGPT enzymes in β major thalassemia patients at Abdul Moeloek Hospital Bandar Lampung.
Hubungan Kadar Serum Feritin Dengan Kejadian Stunting Pada Anak Talasemia β Mayor Rita Agustina; Zulhafis Mandala; Rena Sahara
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 1 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v11i1.263

Abstract

Thalassemia is hemolytic anemia characterized by abnormalities in globin chain synthesis. Hemochromatosis and tissue hypoxia due to anemia are hormonal factors due to the accumulation of iron in the endocrine glands. Problems with endocrine glands and anemia can interfere with growth such as short posture. This study was to determine the correlation of serum ferritin levels with the incidence of stunting in beta-thalassemia major children in Abdul Moeloek Hospital in Lampung in 2019. This research uses an observational analytic method with a cross-sectional approach. The subjects in the study were 60 patients. The instrument used was medical record data. Statistical analysis using the Chi-Square test showed an association between ferritin levels and the incidence of Stunting in Thalassemia patients β Major children at Abdul Moeloek Hospital in Bandar Lampung in 2019 (p-value 0.018. OR 4.67). There is a relationship between ferritin levels with the incidence of Stunting in Thalassemia patients β Major children at Abdul Moeloek Hospital, Bandar Lampung in 2019.
Perbandingan Nilai Indeks Green dan King antara Anemia Defisiensi Besi dengan Thalassemia Astri Pinilih; Syuhada Syuhada; Zulhafis Mandala; Dianthy Novia
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 1 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v11i1.311

Abstract

Background: The definitive differential diagnosis between Thalassemia and iron deficiency anemia is based on the results of HbA₂ electrophoresis, serum iron levels, and ferritin calculations. The purpose of using indices is to distinguish and detect subjects with high probability who need appropriate follow-up and to reduce unnecessary investigative costs. Objective: To determine the difference in the value of the Green & King Index between Iron Deficiency Anemia patients and Thalassemia patients in Abdul Moeloek Regional Hospital in Lampung Province in 2019. Method: This research is a quantitative study with a comparative test by taking secondary data. With the number of samples using a ratio of 1: 1 so that there were 152 people with iron deficiency anemia and 152 people with Thalassemia. Results: The results of statistical analysis using the Mann Whitney U test showed a p-value for comparison of the Green & King index values ​​between iron deficiency anemia patients and thalassemia patients of 0,000 (p <0.05). Conclusion: There is a significant difference in the value of the Green & King index between iron deficiency anemia patients and thalassemia patients in Abdul Moeloek Regional Hospital Lampung Province.
Hubungan Jumlah Kadar Limfosit dan Neutrofil Segmen Pada Apendisitis Akut Mizar Erianto; Zulhafis Mandala; Rio Chairul Anam
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 2 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v12i2.473

Abstract

Appendicitis is one of the most common cases in the field of abdominal surgery which causes acute abdominal pain and requires immediate surgery to prevent complications that are generally dangerous, such as gangrenous, perforation, and even generalized peritonitis. Appendicitis can be found in both men and women with a risk of suffering from appendicitis in their lifetime reaching 7-8%. The highest incidence is reported in the age range of 20 to 30 years. Methodology: The type of research used in this study is an observational analytic study with a cross-sectional study design using medical records as data. The population in this study were all patients with appendicitis recorded in medical records. The data were analyzed using the Spearman test. Results: In this study, 26 people with a percentage of 65% had abnormal lymphocyte counts. as many as 31 people with a percentage of 77.5% who had abnormal neutrophils. For the neutrophil variable with the incidence of appendicitis using the Spearman test, the p-value = 0.005 (p <0.05). In the lymphocyte variable with the incidence of appendicitis using the Spearman test, the p-value = 0.058 (p <0.05) was obtained. Conclusion: There is a significant relationship between neutrophil and appendicitis. Meanwhile, the lymphocyte variable with the incidence of appendicitis had no significant relationship.
Penyuluhan Tentang Protokol Kesehatan Covid -19 Pada Masyarakat Di Puskesmas Sumur Batu Teluk Utara, Bandar Lampung Hasmarullah Fasya; Sandhy Arya Pratama; Zulhafis Mandala; Yesi Nurmalasari; Upik Pebrian
JURNAL KREATIVITAS PENGABDIAN KEPADA MASYARAKAT (PKM) Volume 4 Nomor 1 Februari 2021
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v4i1.3678

Abstract

ABSTRAK Prevalensi kejadian COVID 19 di laporkan sangat cepat hingga hampir tak ada negara atau wilayah di dunia yang absen dari virus Corona. kasus Di Indonesia sendiri pada 22 Desember 2020 terdapat 664. 930 kasus yang positif, dengan pasien meninggal sebanyak 19.880 orang. Di Bandar Lampung sendiri virus Corona mencapai angka 5.464 orang yang positif dan 240 diantaranya meninggal dunia. Covid19 yang di sebabkan  oleh virus severe acute respiratory syndrome coronavirus2 (SARS-CoV-2).COVID- 19 dapat menyebabkan gangguan sistem pernapasan, mulai dari gejala yang ringan seperti flu, hingga infeksi paru-paru, seperti  pneumonia.Upaya pengendalian belum berjalan efektif sebab proses mengenali virus tersebut masih berjalan. Secara umum, penularan paling efektif virus Corona antar manusia adalah droplet atau cairan yang menempel di benda sekitar membuat pembatasan jarak dan sosial harus dilakukan dengan  ketat. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan akan pentingnya menjaga kesehatan. Metode yang digunakan dalam kegiatan ini yaitu penyuluhan kepada masyarakat mengenai cara mencuci tangan,menjaga jarak , memakai masker . Pelaksanaan kegiatan dibantu oleh mahasiswa FK Universitas Malahayati dimulai pada bulan Desember 2020. Hasil dari kegiatan ini adalah meningkatnya pengetahuan Masyarakat sehingga dapat disimpulkan bahwa penyuluhan pada Masyarakat sangat efektif. Kata Kunci: Penyuluhan, COVID 19, Masyarakat  ABSTRACT The prevalence of the incidence of COVID 19 is being reported so fast that almost no country or region in the world is absent from the Corona virus. cases In Indonesia alone on December 22, 2020 there were 664.930 positive cases, with 19,880 patients dying. In Bandar Lampung itself, the Corona virus reached 5,464 positive people and 240 of them died Covid 19 which was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. COVID-19 can cause respiratory system disorders, ranging  from  mild   symptoms  such  as  flu   to  lung   infections,  such  aspneumonia. Control efforts have not been effective because the process ofrecognizing the virus is still ongoing. In general, the most effective transmission of the Corona virus between humans is droplets or liquids that stick to surrounding objects, making social and distance restrictions strictly enforced. The purpose of this activity is to increase knowledge of theimportance of maintaining health. The method used in this activity is counseling the community about how to wash hands, maintain distance, wear masks. The implementation of activities assisted by students of FK Malahayati University began in December 2020. The result of this activity was an increase in community knowledge so that it can be concluded that outreach to the community is very effective. Keywords: Counseling, COVID 19, Community
Penyuluhan Tentang Covid-19 Pada Kader Posyandu Di Puskesmas Pinang Jaya Bandar Lampung Zulhafis Mandala; Dwi Rizki Ramadika; Ni Putu Sudiadnyani; Ratna Purwaningrum; Deviani Utami; Selvia Anggraeni
JURNAL KREATIVITAS PENGABDIAN KEPADA MASYARAKAT (PKM) Volume 4 Nomor 5 Oktober 2021
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v4i5.3716

Abstract

ABSTRAK Dalam kehidupan era globalisasi saat ini terjadi suatu wabah yaitu pandemi COVID-19 dimana munculnya patogen baru yang berkembang secara  pesat. COVID - 19 dapat menyebar dari orang ke orang terutama ketika orang yang terinfeksi melakukan kontak dekat dengan orang lain. Salah satu upaya untuk memutus rantai penyebaran COVID-19 adalah dengan melakukan pencegahan COVID-19 yang diperlukan pemahaman dan pengetahuan serta perilaku yang baik dan benar dari seluruh elemen termasuk anggota masyarakat.Tujuan kegiatan penyuluhan ini untuk menambah wawasan serta pengetahuan bagi masyarakat dan dapat meningkatkan kesadaran masyarakat untuk melakukan upaya pencegahan dan perlindungan diri serta menjalankan protokol kesehatan selama masa pandemik COVID-19. Kegiatan ini dilakukan di Puskesmas Pinang Jaya Bandar Lampung. Kegiatan ini diawali dengan memberikan pertanyaan seputar pengetahuan tentang COVID-19. Dilanjutkan dengan memberikan materi menggunakan power point dan memberikan leaflet. Hasil kegiatan ini adalah didapatkan peningkatan pengetahuan tentang COVID-19 sebanyak 90%. Kegiatan ini merupakan langkah awal untuk meningkatkan pengetahuan guna menjalankan menjalankan kehidupan sehari-hari. Kata Kunci : Penyuluhan, COVID-19, Protokol Kesehatan  ABSTRACT In the current era of globalization, an epidemic has occurred, namely the COVID-19 pandemic, in which the emergence of new pathogens is developing rapidly. COVID-19 can spread from person to person especially when an infected person comes into close contact with other people. One of the efforts to break the chain of the spread of COVID-19 is to prevent COVID-19 which requires good and correct understanding and knowledge and behavior from all elements including members of the community. The purpose of this outreach activity is to add insight and knowledge for the community and to increase awareness community to make efforts to prevent and protect themselves and to carry out health protocols during the COVID-19 pandemic. This activity was carried out at the Pinang Jaya Bandar Lampung Community Health Center. This activity begins with asking questions about knowledge about COVID-19. Followed by providing material using power points and giving leaflets. The result of this activity was a 90% increase in knowledge about COVID-19. This activity is the first step to increase knowledge in order to carry out daily life. Keywords: Counseling, COVID-19, Health Protocol
Program Hidup Bersih Dan Sehat Pada Masa Pandemi Dikelurahan Bakung Selvia Anggraeni; Afrizal Abdul Aziz; Deviani Utami; Abdurrohman Izzudin; Rinto Hadiarto; Zulhafis Mandala
JURNAL KREATIVITAS PENGABDIAN KEPADA MASYARAKAT (PKM) Volume 4 Nomor 2 April 2021
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v4i2.3704

Abstract

ABSTRAK Mewabahnya penyebaran penyakit Corona Virus Diseases-19 atau dikenal dengan Covid19 yang menyebabkan bencana bagi masyarakat hingga mengakibatkan kematian ribuan jiwa diseluruh dunia, tidak terkecuali di Indonesia. Munculnya wabah penyakit ini mendorong pentingnya untuk memberikan edukasi terhadap masyarakat tentang prilaku hidup bersih dan sehat (PHBS). Selain itu, masyarakat perlu mengetahui dengan pasti penularan dan cara pencegahan Covid-19 agar tidak terus mewabah. Masyarakat sangat disarankan untuk tinggal di rumah saja, harus menggunakan masker, pekerja/karyawan bekerja dari rumah (Work From Home/WFH), selalu mencuci tangan dan menerapkan PHBS. PHBS merupakan starategi yang dapat mencegah penyebaran Covod-19. Masyarakat terus dihimbau untuk meningkatkan prilaku hidup bersih dan sehat dalam upaya pencegahan penyebaran Covid-19, karena perilaku masyarakat sangat berperan penting dalam penurunan angka penyebaran Covid-19. PHBS merupakan salah satu starategi dalam pencegahan penyebaran Covid -19 yang sangat efektif dan mudah dilakukan oleh semua lapisan masyarakat. Rekomendasi pemerintah terus menghimbau gerakan PHBS menjadi kunci pencegahan penyebaran Covid-19 pada masa pandemik ini. Melakukan PHBS diharapkan penyebaran Covid-19 dapat dihambat sehingga kejadian tidak bertambah. Oleh karena pentingnya perilaku hidup bersih dan sehat, perlu dilakukan pemberian informasi secara terus menerus sehingga dapat meningkatkan pengetahuan seluruh lapisan masyarakat untuk menerapkan PHBS dalam kehidupan sehari-hari.Kata Kunci: PHBS,COVID19ABSTRACT The outbreak of the Corona Virus Diseases-19 or known as Covid19, which caused disasters for the community, resulted in the death of thousands souls throughout the world, including in Indonesia. The emergence of this disease outbreakencouraging the importance of providing education to the public about behaviorclean and healthy life (PHBS). In addition, people need to know for suretransmission and ways to prevent Covid-19 so that it does not continue to plague. Society immenselyIt is advisable to stay at home only, must use a mask, workers / employeeswork from home (Work From Home / WFH), always wash hands and applyPHBS. PHBS is a strategy that can prevent the spread of Covod-19.The community continues to be urged to improve behavior in a clean and healthy life. Keywords:PHBS , COVID19