Article Per Year (5 Year)
p-Index From 2021 - 2026
0.92
P-Index
This Author published in this journals
All Journal Medicina E-Jurnal Medika Udayana Oto Rhino Laryngologica Indonesiana ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Perikanan Pantura Open Access Indonesian Journal of Medical Reviews Archives of The Medicine and Case Reports
Eka Putra Setiawan
2Departemen Ilmu Kesehatan Telinga Hidung Tenggorok–Bedah Kepala Dan Leher (THT-KL), Fakultas Kedokteran, Universitas Udayana, RSUP Sanglah, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Other

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
Non-Keratinizing Sinonasal Squamous Cell Carcinoma Extending to the Skull Base: Surgical Management with Total Maxillectomy - A Case Study Anak Agung Wira Ryantama; Eka Putra Setiawan; Wayan Lolik Lesmana; Agus Rudi Asthuta; Komang Andi Dwi Saputra; Luh Sartika Sari
Archives of The Medicine and Case Reports Vol. 6 No. 3 (2025): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v6i3.745

Abstract

Sinonasal squamous cell carcinoma (SNSCC) is an uncommon malignancy arising within the nasal cavity and paranasal sinuses, representing approximately 3% of head and neck cancers. The non-keratinizing subtype (NKSCC) presents unique diagnostic and therapeutic challenges, particularly when exhibiting locally advanced disease with extension towards critical structures like the skull base. Management typically involves a multimodal approach centered around surgical resection, often followed by adjuvant therapy. We present the case of a 51-year-old female, employed in the wood furniture industry, presenting with a progressively enlarging right nasal mass initially noted four years after removal of a right cheek lesion. Symptoms included unilateral nasal obstruction, epistaxis, anosmia, and loosening of maxillary teeth. Clinical examination revealed a large, friable mass obliterating the right nasal cavity and extending onto the palate. Computed tomography confirmed an extensive destructive mass involving the right nasal cavity, maxillary sinus, ethmoid sinus, extending to the nasopharynx, parapharyngeal space, masticator space, buccal space, frontal sinuses, and abutting the right internal carotid artery. Biopsy confirmed Non-Keratinizing Squamous Cell Carcinoma. The patient was staged as T4bN2cM0 according to the AJCC 8th edition criteria. Following neoadjuvant chemotherapy, the patient underwent total maxillectomy via a Weber-Ferguson approach with Lynch modification, including placement of a dental obturator. In conclusion, advanced NKSCC involving the skull base requires aggressive, multidisciplinary management. This case highlights the necessity of radical surgical resection, such as total maxillectomy via extended approaches like the Weber-Ferguson with Lynch modification, to achieve oncologic control in extensive T4b disease. Despite the challenges posed by proximity to vital structures, surgery remains the cornerstone of treatment, often requiring adjuvant therapy to optimize outcomes. Long-term follow-up is crucial due to the inherent risk of recurrence.
Salvage Total Laryngectomy with Bilateral Deltopectoral Flap Reconstruction for Metastatic (Stage IVC) Laryngeal Carcinoma: A Case Report Steven Yohanis Latupeirissa; I Wayan Lolik Lesmana; Eka Putra Setiawan; I Gde Ardika Nuaba; Made Lely Rahayu; I Ketut Suanda
Open Access Indonesian Journal of Medical Reviews Vol. 5 No. 5 (2025): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v5i5.781

Abstract

The management of advanced laryngeal squamous cell carcinoma (SCC) that persists or recurs after definitive chemoradiotherapy presents a significant clinical challenge. This challenge is profoundly amplified in the setting of distant metastatic disease (Stage IVC), where the goals of treatment shift from curative intent to palliation and quality of life preservation. Surgical salvage in this context is controversial and reserved for highly selected cases with severe, unmanageable local symptoms. We present the case of a 58-year-old male, a long-term smoker, with Stage IVC (T3N2cM1) laryngeal SCC, complicated by bone metastases. He initially underwent definitive chemoradiotherapy. Ten months later, he presented with progressive local disease, including a fungating cervical mass and impending airway compromise. A palliative salvage total laryngectomy with bilateral Modified Radical Neck Dissection (MRND) was performed to control severe local symptoms. The extensive pharyngocutaneous defect was reconstructed using bilateral pedicled deltopectoral fasciocutaneous flaps. The final histopathology confirmed viable, moderately differentiated SCC with extensive cartilage invasion and, critically, a positive deep resection margin. The postoperative course was managed successfully, with the patient showing significant improvement in local symptoms and quality of life at short-term follow-up. This case highlights the complex decision-making required for palliative surgery in metastatic head and neck cancer. The discussion focuses on the justification for aggressive local intervention to palliate debilitating symptoms, the rationale for selecting the robust bilateral deltopectoral flap for reconstruction in a hostile, irradiated field, and the profound prognostic implications of a positive surgical margin in the salvage setting. In conclusion, palliative salvage total laryngectomy can be a viable strategy to improve quality of life in selected patients with Stage IVC laryngeal cancer and overwhelming local disease. However, achieving complete oncologic clearance is a formidable challenge, and management must be tailored within a multidisciplinary framework.
Co-Authors Agus Rudi Asthuta Anak Agung Wira Ryantama Endah Sri Redjeki I Dewa Gede Arta Eka Putra I Gde Ardika Nuaba I Ketut Suanda I Made Jawi I Made Wiranadha I Wayan Lolik Lesmana I Wayan Lolik Lesmana Komang Andi Dwi Saputra Luh Made Ratnawati Luh Sartika Sari Made Lely Rahayu Ni Ketut Susilawati Ni Putu Oktaviani Rinika Pranitasari Pande Agus Parta Prananda Putu Dian Ariyanti Putri Putu Krisna Yama Dewi Putu Teguh Aryanugraha Sari Wulan Dwi Sutanegara Sa’idah Luthfiyah Steven Yohanis Latupeirissa Sudipta M Sutanegara, Sari Wulan Dwi Suwandara W Wayan Lolik Lesmana Wayan Sudana Yudianto, Sony