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Traditional Herb Used and Training on Preparation Moringa oleifera Lam. Herb as Dip and Capsules Yufri Aldi; Salman Umar; Aditya Alqamal Alianta; Elidahanum Husni
Warta Pengabdian Andalas Vol 31 No 1 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.1.108-115.2024

Abstract

Moringa leaves have grown abundantly in the 50 Kota Regency area. Studies have been carried out regarding moringa leaves, and research has shown that moringa leaves are effective as a medicine to increase the body's immunity. The community needs to know and understand the benefits of Moringa leaves. Based on that circumstance, the Community Service regarding how to process the Moringa leave to be dip preparation and capsule has been conducted in Jorong Padang Kandis, VII Koto Talago Sub-district, Guguk District, 50 Kota Regency, West Sumatra. The activity was carried out on 19 August 2023. The participants were the Family Welfare Movement (PKK) and Bundo Kandung groups in Jorong Padang Kandis, attended by 100 participants. The method was lectures and training on preparing Moringa herb leaf preparations and making Moringa leaf capsules, which the community can use directly. Community services topics were "The Utilisation of Traditional Medicines" and "The Efficacy and Research Results of Moringa Leaves." The training was on making Moringa leaf powder based on suitable traditional medicine-making methods, such as dips and capsules from Moringa leaf powder and extract. Community service helped the community understand that Moringa leaves can be used as a traditional medicine to protect the body from infection with microorganisms. The community also made powder packaged as a dip preparation, used like tea bags and put it into capsules.
PREPARATION AND CHARACTERIZATION PHISICOCHEMICAL PROPERTIES OF MULTI COMPONENT KETOPROFEN WITH CO-FORMER GLUTAMINE Helen Sonita; Erizal Zaini; Salman Umar
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.799

Abstract

Ketoprofen is a non-steroidal anti-inflammatory compound (NSAID) which has low solubility in water. This study aimed to increase the dissolution rate of ketoprofen by forming multicomponent ketoprofen-glutamine in ratios of 1:1, 1:2, and 2:1 using the solid-state grinding method. The samples were characterized using Powder X-Ray Diffractometry (PXRD), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared (FTIR) Spectroscopy, Scanning Electron Microscope (SEM), solubility, dissolution rate, and stability tests. These results indicated the formation of a eutectic mixture of ketoprofen-glutamine. From the study of the ketoprofen–glutamine eutectic mixture, the eutectic point at a ratio of 1:1 was obtained at 95.51°C. The PXRD spectra did not show new crystal habits; the solubility test of the eutectic mixture of ketoprofen-glutamine showed increases of 2.450, 2.518, and 2.374 times, respectively. The eutectic mixture of ketoprofen–glutamine had rod-like crystal particles that formed and aggregated. The samples showed an increased dissolution rate of ketoprofen. The stability test showed that ketoprofen-glutamine was stable during storage at 75% relative humidity (RH) and 40 °C for 6 months; there was only a decrease in intensity, as seen from the PXRD spectrum. Keywords: eutectic mixture, ketoprofen, glutamine, solubility, dissolution rate, stability