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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Buletin Farmatera Narra J
Amru Sofian
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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PROFIL PENDERITA TUMOR OVARIUM GERMINAL DI RSUD ARIFIN ACHMAD PROVINSI RIAU PERIODE JANUARI 2008 – DESEMBER 2012 Pratama, Gerry; Sofian, Amru; Chandra, Fifia
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Ovarian tumour is one of neoplasma that can be found on female genitalia system, which is formed by benign wether malignant ovarium cells and can be grouped by its origin such as epithelial, germinal, and stroma ovarian tumour. Age, parity, cancer in family history, menarche history and application of hormonal contraception can be risk factors to germinal ovarian tumour to occurs.This is a descriptive and retrospective study, conducted to discover profile of germinal ovarian tumour patients in General Hospital Arifin Achmad Riau Province. From General Hospital Arifin Achmad’s medical records on January 2008-December 2012, 78 cases of germinal ovarian tumour have been found, with the age of majority was in the age 23-32 years old (36,11%), most parity was multiparity (40,27%) and most commonly histopatological type was mature teratoma (76,39%). Cancer in family history can be found in 29 patients (40,27%) which about 17 patients with mature teratoma (23,61%), followed by 8 patients with dysgerminoma (11,11%) and 4 patients with immature teratoma (5,55%). Based on menarche history, distribution profile by the age of majority was 10-13 years old (58,3%). About 62,5% patients didn’t use hormonal contraception. Most commonly CA 125 tests with positive results were 18 examinations (25%) wich can be found mature teratoma on 12 examinations (16,67%) followed by dysgerminoma on 4 examinations (5,56%) and immature teratoma on 2 examinations (2,77%). CEA tests showed positive results for about 14 examinations (19,44%), where mature teratoma can be found on 8 examinations (11,11%), followed by dysgerminoma on 4 examinations (5,56%) and immature teratoma on 2 examinations (2,77%). Salphingoophorectomy were the most common therapy that have been chosen (54,17%).Keywords: ovarian tumour, germinal ovarian tumour, risk factors
GAMBARAN HASIL PEMERIKSAAN SITOLOGI PENDERITA KANKER SERVIKS PASCA TERAPI RADIASI BERDASARKAN KELOMPOK UMUR DI INSTALASI RADIOTERAPI RSUD ARIFIN ACHMAD PERIODE TAHUN 2009–2013 Herman, Awanda; Sofian, Amru; Chandra, Fifia
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Radiation therapy is a therapeutic option for cervical cancer, and expected to have optimal outcomes, The results of radiation therapy is different for each patient depending on the sensitivity of cancer cells to radiation that is influenced by age, it can be reviewed by looking at the cell's response to radiation based on the presence or absence of malignant cells that found in the results of cytologic examination after radiation therapy. This research aimed to describe the results of cytological examination of cervical cancer patients after radiation therapy by age group in Radiotherapy Installation Arifin Achmad general hospital of Riau Province Period 2009-2013. The type of this research was descriptive retrospective with population are medical recodrs of cervical cancer patients who had undergone radiation therapy in the form of 25 full time external radiation therapy without chemotherapy in Radiotherapy Installation Arifin Achmad General Hospital of Riau period 2009 to 2013. The sample is the medical record that eligible as population that is as much as 78 medical records. The result of this research was found the largest age group who performed radiation therapy was 40-49 years old (41%), while the largest age group who have a cytological examination found no malignant cells most is 40-49 years old (12.8%), the age group that has the results malignant cells are found in the form of the age group 40-49 years old and 50-59 years old with patients respectively (1.3%) and the largest age group who do not have the data post-radiation cytology result is 40-49 years old (26 , 9%). The largest age group who have a cytological examination found no malignant cells most is people who do a cytological examination more than once that is age group > 60 years old (55.6%) and resulted in the malignant cells are found in the age group 50-59 years old (11 , 1%). Key words: cervical cancer, cervical cancer radiation, cytology results based on age
GAMBARAN PEMERIKSAAN INPEKSI VISUAL ASETAT SEBAGAI DETEKSI LESI PRAKANKER SERVIKS DI HOTSPOT JALAN TUANKU TAMBUSAI KECAMATAN SUKAJADI PEKANBARU Novri, Dhini Aiyuli; sofian, Amru; Fidiawati, Wiwit Ade
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is the third most frequent cancer in women in Indonesia. Indirect female sex worker are in high risk for having cervical cancer. World Health Organization had recommended an alternative approach for developing countries with down staging concept of cervical malignancy with visual inspection with acetic acid (VIA) to detect cervical precancerous lesion. This research was carried out at hotspot Tuanku Tambusai Street, Pekanbaru aimed to describe the characteritics of respondent and to detect displastic cervical epithelial cells with VIA. The result showed from 31 indirect female sex worker, 52 % were diagnosed with positive acetowhite appereance (positive VIA). Conclusion of the study that displastic cervical epithelial cells of indirect female sex worker who has high risk for having cervical cancer should be reffered for further follow up.Keywords: Visual inspection with acetic acid, Cervical cancer, Cervical precancerous lesion, Indirect female sex worker.
GAMBARAN HASIL SITOLOGI SERVIKS WANITA PEKERJA SEKSUAL TIDAK LANGSUNG PADA HOTSPOT X KECAMATAN MARPOYAN DAMAI Rahmadani, Fetty Try; Ade, Wiwit; Sofian, Amru
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 2 (2016): Wisuda Oktober 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

ABSTRACTCervical cancer is the second most frequent cancer in women in the world after breast cancer. Indirect female sex workers have high risk to get cervical cancer. The number of cervical cancer cases can be reduced with Pap smear screening. The purpose of this study was to know the result of cervical smear cytology examination toward indirect female sex workers at hotspot X Marpoyan Damai Pekanbaru. The method of this research is descriptive. The population of this study were all of indirect female sex workers at hotspot X Marpoyan Damai Pekanbaru and the samples were takwn with total sampling methode. The result showed that there were 33 Consist 6% diagnosed with negative intraepithelial lesion or malignancy (Bacterial vaginosis), 30% diagnosed with LSIL and 64% diagnosed with ASCUS. The conclusion is ASCUS was the most common intraepithelial lesion of cervical cancer on indirect female sex workers at hotspot X Kecamatan Marpoyan Damai Pekanbaru. Keywords:Cervical smear, Pap smear Cervical cancer, Indirect Female Sex Workers, Hotspot X Marpoyan Damai
GAMBARAN PEMERIKSAAN INSPEKSI VISUAL ASETAT SEBAGAI DETEKSI LESI PRAKANKER SERVKS PADA WANITA PEKERJA SEKSUAL TIDAK LANGSUNG DI HOTSPOT X KECAMATAN LIMAPULUH PEKANBARU Islami, Nursida; Fidiawati, Wiwit Ade; Sofian, Amru
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 1 (2016): Wisuda Februari 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

ABSTRACKTCervical cancer wasthe second highest cancerin women in Indonesia. Indirect female sex workers had high risk for cervical cancer. World Health Organization (WHO) suggested screening to reduce the incidence of cervical cancer, alternative screening method which was relatively easy and often done in developing countries was Visual Inspection with Acetic Acid (VIA). This research was executed at hotspot X, Limapuluh district, Pekanbaru with the aim of describing the characteristics of respondents and to detect abnormal cervical epithelium using VIA. This research used descriptive research design, by using total sampling method there were 31 respondents. The result showed that 68% negative and 32% positive VIA. From the result of this study, it could be concluded that the majority of indirect female sexworkers (IFSW) had negative result of VIA, other wise IFSW who had positive result of VIA were suggested to get further examination.Keywords:Visual inspection with acetic acid, Cervical cancer, Indirect female sex workerPENDAHULUANKanker serviks merupakan keganasan pada serviks yang disebabkan oleh infeksi Human Papillomavirus khususnya tipe 16, 18, 31 dan 45.1,2 kanker ini menduduki peringkat keempatsebagai jenis kanker terseri
GAMBARAN PEMERIKSAAN INSPEKSI VISUAL ASETAT SEBAGAI DETEKSI LESI PRAKANKER SERVIKS PADA WANITA PEKERJA SEKSUAL TIDAK LANGSUNG DI HOTSPOT Y KECAMATAN TENAYAN RAYA PEKANBARU Ovinitha, Sarah; Fidiawati, Wiwit Ade; Sofian, Amru
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 1 (2016): Wisuda Februari 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

ABSTRACTCervical cancer is a malignancy in the epithelial cells of the cervix that can be prevented and detected earlier, but still ranks as the fourth most common cancer in women worldwide. Early detection of cervical cancer in developing countries such as Indonesia that was recommended by World Health Organization (WHO) is Visual Inspection with Acetic Acid (VIA). Indirect Female Sex Workers (FSW) have a higher risk of cervical cancer. The aim of this study is to reveal the results of VIA on indirect FSW at hotspot Y District Tenayan Raya Pekanbaru. The method of this research is descriptive observational. The study population was WPS-TL residing in the hotspot Y District Tenayan Raya Pekanbaru and the samples were taken with total sampling method. The results showed that among 44 FSWs, 17 people (38.6%) of them had acetowhite on the VIA examination (positive VIA). It is concluded that the majority of indirect FSWs at hotspot Y District Tenayan Raya Pekanbaru have a negative IVA results.Key words : Visual Inspection with Acetic Acid (VIA), Cervical Cancer, Indirect Female Sex Worker (FSW), Hotspot Y
Efektivitas HE4 sebagai Metode Skrining Terbaru untuk Diagnosis Dini Kanker Ovarium Amru Sofian; Hendra Perkasa; Ega Rahman Evsya; Riyan M Darundryo
Jurnal Ilmu Kedokteran Vol 5, No 2 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.844 KB) | DOI: 10.26891/JIK.v5i2.2011.88-93

Abstract

The tumor marker CA125 is one of the currently used biomarkers to detect ovarian cancer. The tumormarker CA125 also elevated in other diseases. Human epididymis protein 4 is used as a new biomarker forearly detection of ovarian cancer. Human epididymis protein 4 is increased in almost all patients withovarian cancer and increased only slightly at a fraction of other diseases. Human epididymis protein 4 hasa better effectiveness in detecting ovarian cancer when combined with CA125. From the study of literaturefound that the combination of HE4 and CA125 had a specificity of 96.3% and 92.9% sensitivity.
Gambaran Hasil Pemeriksaan Sitologi Serviks Wanita Pekerja Seksual Tidak Langsung pada Hotspot Maredan Kecamatan Tenayan Raya Pekanbaru Wiwit Ade; Sindy Oktaviani; Amru Sofian
Jurnal Ilmu Kedokteran Vol 10, No 1 (2016): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (62.193 KB) | DOI: 10.26891/JIK.v10i1.2016.54-62

Abstract

Cervical cancer is a malignancy of the cervix that can be prevented, but the cause of death of women due to cancer.Cervical cancer is the second most frequent cancer in women in the world. Indirect female sex workers have a higherrisk of cervical cancer. The aim of this research was to figure out description of cervical smear examination in indirectfemale sex workers at hotspot Maredan Tenayan Raya Pekanbaru. Population of this experiment were all indirectfemale sex workers at hotspot Maredan Tenayan Raya Pekanbaru and samples were taken with total sampling method.The result showed that there were 44 people consist 4% diagnosed with HSIL, 25% were diagnosed with LSIL, 30%diagnosed with ASCUS and 41% with negative for intraepithelial lesion or malignancy (Bacterial vaginosis,Trichomonas vaginalis, Candidiasis presents).
Gambaran Kualitas Hidup Pasien Kanker Serviks Yang Menjalani Radioerapi Di RSUD Arifin Achmad Provinsi Riau Periode 2011 – 2013 Azizah "; Amru Sofian; Suyanto "
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is a malignant tumor derived from primary squamous epithelial cells that grow on the surface of the epithelial or outer layer of the cervix, and is caused by virus infections Human Papiloma Virus (HPV). One of the given therapy on patients of cervical cancer is radiotherapy. Radiotherapy is done by people with cervical cancer that can affect the quality of life of the respondent which can be assessed by using the WHOQOL questionnair. The purpose of this research is to know the description of the quality of life of patients with cervical cancer undergoing radiotherapy. This research is descriptive research with cross sectional approach implemented in June 2014. There are 31 people with cervical cancer undergoing radiotherapy. From this research found the age of respondents in the age group 40-49 years 50-59 years and the age group 60-69 years were relatively the same lot. The majority of respondents were Malays (58,06 percent). Most respondents were the PRIMARY education (38,80). Most respondents work was as the IRT (90,32 per cent). The respondents underwent radiotherapy most within > 5 weeks (100%). On cervical cancer patients undergoing radiotherapy at the PROVINCIAL HOSPITAL Arifin Achmad Riau Province found the quality of life in both categories as much as 61,30%.Key word: cervical cancer, radiotherapy , quality of life
GAMBARAN HASIL TERAPI RADIASI DAN KEMORADIASI PASIEN KANKER SERVIKS DI RSUD ARIFIN ACHMAD PEKANBARU PERIODE 2009-2013 Fadilla Rizki Putri; Amru Sofian; Dimas Pramita Nugraha
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is the third most common cancer in women in Indonesia. Many cervical cancer cases were found in an advanced stage, so that they were treated by radiation or chemoradiation. Radiation is divided into external radiation and internal radiation. There is no internal radiation done in Arifin Achmad General Hospital Pekanbaru, so that they only use complete external radiation treatment for 25 times. After the therapy, the patient will do a follow-up treatment of pap smears to assess the cancer cells. This research was conducted in Radiotherapy Installation, Pathology Installation and Medical Records Installation at Arifin Achmad General Hospital Pekanbaru to study and reveal the results of radiation and chemoradiation therapy in cervical cancer patients at Arifin Achmad General Hospital Pekanbaru. The results showed that of 79 patients treated with cervical cancer radiation, only 29 patients did the follow up treatment whilst of 31 patients treated with cervical cancer chemoradiation, only 6 patients did the follow up treatment. Only 2 patients treated by radiation were found to have malignant cells in the pap smear treatment. Meanwhile, in cervical cancer patients treated by chemoradiation, 2 patients were still found malignant cells and 1 patient experienced a recurrence. Once treated with radiation, malignant cells on pap smears are found only in 2 patients, while 27 patients were not found and only 1 patient who experienced a recurrence. After chemoradiation therapy in 6 cervical cancer patients who did the follow up, malignant cells are found in 2 patients and in 4 patients no malignant cells was found, while the other 2 patients experienced recurrence. The conclusion of this study is the incompleteness of the data found in the medical records, low patient adherence to do follow-up treatment after therapy, and the lack of education and information given by the health professionals to patients to do a follow up treatment.Keywords: Cervical cancer, Complete radiation , Chemoradiation, Pap smear
Co-Authors Ade, Wiwit Admiral, Muhammad Z. Awanda Herman Azizah " Bayu Fajar Pratama Dhini Aiyuli Novri Dhini Aiyulie Novri Dimas Pramita Nugraha Donel S Dyah Astrid Astrid Ega Rahman Evsya Eka Bebasari Fadilla Rizki Putri Farniga, Arnaldi Fatmawati " Fifia Chandra Gerry Pratama Hendra Perkasa Ika A. Rini, Ika A. Ilmiah, Zidny Kemal, Rahmat A. Mahargyarani, Azza E. Mardhiah Gaffar Maya Savira Monaliza " Nursida Islami, Nursida Ovinitha, Sarah Putra, Andani E. Putri Deas H Rachmadina, Rachmadina Rahmadani, Fetty Try Razali, Renardy R. Riyan M Darundryo Sindy Oktaviani Suyanto " Trigen Yulis Rahmat Yulis Tryanda Ferdyansyah Vicennia Serly Wiwit Ade Wiwit Ade Fidiawati Yanti Ernalia