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All Journal Proceedings of the International Conference on Applied Science and Health Global Health Management Journal Tunas Medika Jurnal Kedokteran & Kesehatan Wiga : Jurnal Penelitian Ilmu Ekonomi Berita Kedokteran Masyarakat The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal Of Economic Sciences (Ekuisci)
Catur Setiya Sulistiyana
Fakultas Kedokteran Universitas Swadaya Gunung Jati
Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Proceedings of the International Conference on Applied Science and Health

 1 
EFFECT OF TREE MARIGOLD (Tithonia diversifolia (HEMSL.) A. GRAY) LEAVES INFUSION AND ETHANOL EXTRACT ON BLOOD GLUCOSE LEVEL AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED MALE WISTAR RATS Maulidiany, Rachma Ayu; Suhaeni, Eni; Sulistiyana, Catur Setiya; Sari, Ariestya Indah Permata
Proceedings of the International Conference on Applied Science and Health No 3 (2018)
Publisher : Proceedings of the International Conference on Applied Science and Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (563.222 KB)

Abstract

Background: Common Indonesians often use alternative therapy for Diabetes Mellitus (DM) due to its high prevalence. Tree marigold (Tithonia difersivolia (Hemsl.) A. Gray) leaves show its positive effect in decreasing blood glucose level. Thus, it is important to analyze the negative effect of consuming the proposing alternative including its toxicity level to vital organs. This study aims to observe the blood glucose level and liver histopathology in streptozotocin-induced diabetic male rats treated by infusion and ethanol extract of the tree marigold leaves. Methods: Pretest and posttest with control group design experiment was conducted to analyze effect on blood glucose level and posttest only with control group design was for determining liver histopathology. Twenty-four male white rats (Wistar strain) were randomly divided into 4 groups: normal control group (KN), positive control group (K+) treated with 0.45mg/kg of glibenclamid, treatment group 1 (P1) treated by 100 mg/kg of tree marigold leaves ethanol extract, and treatment group 2 (P2) treated by 1373 mg/kg of tree marigold leaves infusion. The rats at the groups of K+, P1, and P2 were induced by streptozotocin to reach hyperglycemic state. Comparison of blood glucose level effect between infusion and ethanol extract was analyzed by One-Way ANOVA continued by post-hoc test, while comparison of liver histopathology effect was determined by Kruskal-Wallis continued by Mann-Whitney test. Results: Significant differences of blood glucose level decrease were found in all groups. Group P2 significantly decreased blood glucose level more than P1 (p=0.000) as much as 124.97 mg/dl and 101.46 mg/dl respectively. Significant differences of liver histopathology were obtained between KN vs K(+), KN vs P2, K(+) vs P2, and P1 vs P2. Group P2 showed more severe of liver histopathology changes than P1 (p=0.025). Conclusion: Tree marigold leaves extract is more effective in lowering blood glucose level and has less toxic effect to liver histopathology than its infusion. 
BRINGING MEDICAL GENETICS TO THE PUBLIC: THE CHALLENGES FOR INDONESIAN MEDICAL FACULTIES Sulistiyana, Catur Setiya
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Abstract

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THE CORRELATION BETWEEN MOTHER’S KNOWLEDGE, EDUCATION AND FAMILY INCOME WITH NUTRITIONAL STATUS OF TODDLER (AGED 1-5 YEARS) Pratiwi, Ika Rena; Alibasjah, Ricardi W; Sulistiyana, Catur Setiya
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (615.633 KB)

Abstract

Background: The role of mothers in the growth and development of toddlers is very important. Mothers must know and understand what is needed for that process because this will affect the nutritional status of toddlers. This relates to knowledge, education, and mother?s income which will affect the provision of food intake for infants. Nutritional status of children is still one of the problems in the world. The incidence of malnutrition in the world reached 104 million children and malnutrition is one-third causes of child mortality worldwide. Basic Health Research in 2007, the prevalence of toddler malnutrition in Indonesia was 18.4%, an increase from 2013 to 19.6% and decreased again in 2018 to 17.7% in the year.Aims: To find out the correlation between mothers? knowledge level, education and family revenue with nutritional status of toddler.Methods: This research used  Cross Sectional design, used Accidental sampling techniques. The samples were taken 289 toddlers (1-5 years). The data obtained were analysed using spearman test.Results: Spearman test results showed there is no significant correlation (p> 0.05) between mother?s knowledge level, education and family revenue with nutritional status of toddler.Conclusion: There is no correlation between mother?s knowledge level, education and family revenue with nutritional status of toddler in Kalitanjung Cirebon Health Center. Keywords: Knowledge level, Mother?s education, Revenue, Nutritional status of toddler
EFFECT OF TREE MARIGOLD (Tithonia diversifolia (HEMSL.) A. GRAY) LEAVES INFUSION AND ETHANOL EXTRACT ON BLOOD GLUCOSE LEVEL AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED MALE WISTAR RATS Rachma Ayu Maulidiany; Eni Suhaeni; Catur Setiya Sulistiyana; Ariestya Indah Permata Sari
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Common Indonesians often use alternative therapy for Diabetes Mellitus (DM) due to its high prevalence. Tree marigold (Tithonia difersivolia (Hemsl.) A. Gray) leaves show its positive effect in decreasing blood glucose level. Thus, it is important to analyze the negative effect of consuming the proposing alternative including its toxicity level to vital organs. This study aims to observe the blood glucose level and liver histopathology in streptozotocin-induced diabetic male rats treated by infusion and ethanol extract of the tree marigold leaves. Methods: Pretest and posttest with control group design experiment was conducted to analyze effect on blood glucose level and posttest only with control group design was for determining liver histopathology. Twenty-four male white rats (Wistar strain) were randomly divided into 4 groups: normal control group (KN), positive control group (K+) treated with 0.45mg/kg of glibenclamid, treatment group 1 (P1) treated by 100 mg/kg of tree marigold leaves ethanol extract, and treatment group 2 (P2) treated by 1373 mg/kg of tree marigold leaves infusion. The rats at the groups of K+, P1, and P2 were induced by streptozotocin to reach hyperglycemic state. Comparison of blood glucose level effect between infusion and ethanol extract was analyzed by One-Way ANOVA continued by post-hoc test, while comparison of liver histopathology effect was determined by Kruskal-Wallis continued by Mann-Whitney test. Results: Significant differences of blood glucose level decrease were found in all groups. Group P2 significantly decreased blood glucose level more than P1 (p=0.000) as much as 124.97 mg/dl and 101.46 mg/dl respectively. Significant differences of liver histopathology were obtained between KN vs K(+), KN vs P2, K(+) vs P2, and P1 vs P2. Group P2 showed more severe of liver histopathology changes than P1 (p=0.025). Conclusion: Tree marigold leaves extract is more effective in lowering blood glucose level and has less toxic effect to liver histopathology than its infusion. 
BRINGING MEDICAL GENETICS TO THE PUBLIC: THE CHALLENGES FOR INDONESIAN MEDICAL FACULTIES Catur Setiya Sulistiyana
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

-
THE CORRELATION BETWEEN MOTHER’S KNOWLEDGE, EDUCATION AND FAMILY INCOME WITH NUTRITIONAL STATUS OF TODDLER (AGED 1-5 YEARS) Ika Rena Pratiwi; Ricardi W Alibasjah; Catur Setiya Sulistiyana
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The role of mothers in the growth and development of toddlers is very important. Mothers must know and understand what is needed for that process because this will affect the nutritional status of toddlers. This relates to knowledge, education, and mother’s income which will affect the provision of food intake for infants. Nutritional status of children is still one of the problems in the world. The incidence of malnutrition in the world reached 104 million children and malnutrition is one-third causes of child mortality worldwide. Basic Health Research in 2007, the prevalence of toddler malnutrition in Indonesia was 18.4%, an increase from 2013 to 19.6% and decreased again in 2018 to 17.7% in the year.Aims: To find out the correlation between mothers’ knowledge level, education and family revenue with nutritional status of toddler.Methods: This research used  Cross Sectional design, used Accidental sampling techniques. The samples were taken 289 toddlers (1-5 years). The data obtained were analysed using spearman test.Results: Spearman test results showed there is no significant correlation (p> 0.05) between mother’s knowledge level, education and family revenue with nutritional status of toddler.Conclusion: There is no correlation between mother’s knowledge level, education and family revenue with nutritional status of toddler in Kalitanjung Cirebon Health Center. Keywords: Knowledge level, Mother’s education, Revenue, Nutritional status of toddler
BRINGING MEDICAL GENETICS TO THE PUBLIC: THE CHALLENGES FOR INDONESIAN MEDICAL FACULTIES Catur Setiya Sulistiyana
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

-
THE CORRELATION BETWEEN MOTHER’S KNOWLEDGE, EDUCATION AND FAMILY INCOME WITH NUTRITIONAL STATUS OF TODDLER (AGED 1-5 YEARS) Ika Rena Pratiwi; Ricardi W. Alibasjah; Catur Setiya Sulistiyana
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The role of mothers in the growth and development of toddlers is very important. Mothers must know and understand what is needed for that process because this will affect the nutritional status of toddlers. This relates to knowledge, education, and mother’s income which will affect the provision of food intake for infants. Nutritional status of children is still one of the problems in the world. The incidence of malnutrition in the world reached 104 million children and malnutrition is one-third causes of child mortality worldwide. Basic Health Research in 2007, the prevalence of toddler malnutrition in Indonesia was 18.4%, an increase from 2013 to 19.6% and decreased again in 2018 to 17.7% in the year. Aims: To find out the correlation between mothers’ knowledge level, education and family revenue with nutritional status of toddler. Methods: This research used Cross Sectional design, used Accidental sampling techniques. The samples were taken 289 toddlers (1-5 years). The data obtained were analysed using spearman test. Results: Spearman test results showed there is no significant correlation (p> 0.05) between mother’s knowledge level, education and family revenue with nutritional status of toddler. Conclusion: There is no correlation between mother’s knowledge level, education and family revenue with nutritional status of toddler in Kalitanjung Cirebon Health Center. Keywords: Knowledge level, Mother’s education, Revenue, Nutritional status of toddler
EFFECT OF TREE MARIGOLD (Tithonia diversifolia (HEMSL.) A. GRAY) LEAVES INFUSION AND ETHANOL EXTRACT ON BLOOD GLUCOSE LEVEL AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED MALE WISTAR RATS Rachma Ayu Maulidiany; Eni Suhaeni; Catur Setiya Sulistiyana; Ariestya Indah Permata Sari
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Common Indonesians often use alternative therapy for Diabetes Mellitus (DM) due to its high prevalence. Tree marigold (Tithonia difersivolia (Hemsl.) A. Gray) leaves show its positive effect in decreasing blood glucose level. Thus, it is important to analyze the negative effect of consuming the proposing alternative including its toxicity level to vital organs. This study aims to observe the blood glucose level and liver histopathology in streptozotocin-induced diabetic male rats treated by infusion and ethanol extract of the tree marigold leaves. Methods: Pretest and posttest with control group design experiment was conducted to analyze effect on blood glucose level and posttest only with control group design was for determining liver histopathology. Twenty-four male white rats (Wistar strain) were randomly divided into 4 groups: normal control group (KN), positive control group (K+) treated with 0.45mg/kg of glibenclamid,treatment group 1 (P1) treated by 100 mg/kg of tree marigold leaves ethanol extract, and treatment group 2 (P2) treated by 1373 mg/kg of tree marigold leaves infusion. The rats at the groups of K+, P1, and P2 were induced by streptozotocin to reach hyperglycemic state. Comparison of blood glucose level effect between infusion and ethanol extract was analyzed by One-Way ANOVA continued by post-hoc test, while comparison of liver histopathology effect was determined by Kruskal-Wallis continued byMann-Whitney test. Results: Significant differences of blood glucose level decrease were found in all groups. Group P2 significantly decreased blood glucose level more than P1 (p=0.000) as much as 124.97 mg/dl and 101.46 mg/dl respectively. Significant differences of liver histopathology were obtained between KN vs K(+), KN vs P2, K(+) vs P2, and P1 vs P2. Group P2 showed more severe of liver histopathology changes than P1 (p=0.025). Conclusion: Tree marigold leaves extract is more effective in lowering blood glucose level and has less toxic effect to liver histopathology than its infusion.
Co-Authors Ahmad Fariz Malvi Z Zein Alibasjah, Ricardi W Almadevy M.J, Anindhita Apriyanto, Dadan Ramadhan Ariestya Indah Permata Sari Ariestya Indah Permata Sari Atang Kusman Azhar Affandi Dela Destiani Aji Dwi Listiany Corneli Eni Suhaeni Febri Yudha Adhi Kurniawan Horas Djulius Ika Rena Pratiwi Ika Rena Pratiwi Ismayanti Ismayanti Jusa Samara Brajamusti Maulidiany, Rachma Ayu Nurlita Fauziyyah Basri Pratamawati, Tiar M Pratiwi, Ika Rena Purwadi Purwadi R Vivi Meidianawaty Rachma Ayu Maulidiany Rachma Ayu Maulidiany Ricardi W Alibasjah Ricardi W. Alibasjah Risnandya Primanagara Sari, Ariestya Indah Permata Satrianugraha, Muhammad Duddy Septiawati, Ayu Dwi Sri Hendratno Sri Marfuati Sugeng, Santoso Susi Susanti Tiar Masykuroh Pratamawati Tissa Octavira Permatasari Tissa Octavira Permatasari Uswatun Khasanah Wahidin, Dea Triasari Indriyanti Yani Yani Yogi Irawan Yuelsa Febriyanti Zamzam Ahmad Fauzan Zulkifli Ahmad