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EFFECT OF TREE MARIGOLD (Tithonia diversifolia (HEMSL.) A. GRAY) LEAVES INFUSION AND ETHANOL EXTRACT ON BLOOD GLUCOSE LEVEL AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED MALE WISTAR RATS
Maulidiany, Rachma Ayu;
Suhaeni, Eni;
Sulistiyana, Catur Setiya;
Sari, Ariestya Indah Permata
Proceedings of the International Conference on Applied Science and Health No 3 (2018)
Publisher : Proceedings of the International Conference on Applied Science and Health
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Background: Common Indonesians often use alternative therapy for Diabetes Mellitus (DM) due to its high prevalence. Tree marigold (Tithonia difersivolia (Hemsl.) A. Gray) leaves show its positive effect in decreasing blood glucose level. Thus, it is important to analyze the negative effect of consuming the proposing alternative including its toxicity level to vital organs. This study aims to observe the blood glucose level and liver histopathology in streptozotocin-induced diabetic male rats treated by infusion and ethanol extract of the tree marigold leaves. Methods: Pretest and posttest with control group design experiment was conducted to analyze effect on blood glucose level and posttest only with control group design was for determining liver histopathology. Twenty-four male white rats (Wistar strain) were randomly divided into 4 groups: normal control group (KN), positive control group (K+) treated with 0.45mg/kg of glibenclamid, treatment group 1 (P1) treated by 100 mg/kg of tree marigold leaves ethanol extract, and treatment group 2 (P2) treated by 1373 mg/kg of tree marigold leaves infusion. The rats at the groups of K+, P1, and P2 were induced by streptozotocin to reach hyperglycemic state. Comparison of blood glucose level effect between infusion and ethanol extract was analyzed by One-Way ANOVA continued by post-hoc test, while comparison of liver histopathology effect was determined by Kruskal-Wallis continued by Mann-Whitney test. Results: Significant differences of blood glucose level decrease were found in all groups. Group P2 significantly decreased blood glucose level more than P1 (p=0.000) as much as 124.97 mg/dl and 101.46 mg/dl respectively. Significant differences of liver histopathology were obtained between KN vs K(+), KN vs P2, K(+) vs P2, and P1 vs P2. Group P2 showed more severe of liver histopathology changes than P1 (p=0.025). Conclusion: Tree marigold leaves extract is more effective in lowering blood glucose level and has less toxic effect to liver histopathology than its infusion.Â
CALCULATING COLONY OF Candida spp. AMONG CHILDREN WITH INTELLECTUAL DISABILITY IN CIREBON
Oktaviani, Dhini;
Amanah, Amanah;
Suhaeni, Eni;
Primanagara, Risnandya
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
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Background: Children and adults with Intellectual Disability and Autism Spectrum Disorders (ASD) have decreased intestinal permeability and enzyme activity, causing gastrointestinal (GI) problems that are more frequent and more severe than in children from the general population. The immune system which is part of the intestinal barrier in children with Intellectual Disability (ID) experiences various disorders and becomes more susceptible to fungal invasion, such as Candida spp. This present study aims to calculate the colony of Candida spp. in the digestive tract of Children with Intellectual Disability (ID) in the city of Cirebon.Method: This is an observational study with cross-sectional design using purposive sampling. The study was conducted in November 2018-February 2019. The sample (ID) group consists of 31 individuals from Special Needs School and 60 individuals from National elementary school (non-ID) in the city of Cirebon. The inclusion criteria were children ages 6-12 years and the exclusion criteria were children under antifungal treatment and children under cytotoxic or immunosuppressive drugs. The fecal samples from the ID group and non-ID were examined at the Laboratory of the Faculty of Medicine, Universitas Swadaya Gunung Jati Cirebon, Indonesia using Digital Colony counter. Collected data were stored and analyzed using computer aided Statistical program. Mann-Whitney analysis of variance techniques were used to test the hypotheses. Results: The results showed that there are significant differences in the colonies of Candida spp. between the ID group and non-ID group. Median colony of Candida spp. in the ID group is 39.00 with mean colony of 126.90 while the median colony of non-ID group is 3.00 with mean colony of 40.93 (p<0.001).Conclusion: There are significant differences between the Candida spp. colonies in the ID group with the non-ID.
EFFECT OF PHYSICAL ACTIVITY AND FAST FOOD CONSUMPTION FREQUENCY ON OVERWEIGHT LEVEL AMONG HIGH SCHOOL ADOLESCENT
Harlianti, Lita;
Pratiwi, Witri;
Nauphar, Donny;
Suhaeni, Eni
Proceedings of the International Conference on Applied Science and Health No 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
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Background: Obesity was believed to be one of the risk factors of degenerative diseases, such as diabetes mellitus, hypertension, and coronary heart disease. Obesity occurred gradually that started with overweight. Risk factors for overweight are lack of physical activity, and consumption of high caloric fatty food which may cause accumulation of fats inside the body. This research aims to examine the effect of physical activity and fast food consumption frequency on overweight level among high school adolescent in Cirebon. Methods: It was a cross-sectional study conducted among 262 high school students aged 15-17 years using stratified random sampling. Results: The result based on Spearman correlation test showed negative correlation between physical activity and overweight level with p= 0,001 (p< 0,05) and correlation coefficient of -0,627. There was positive correlation between consumption fast food frequency with overweight with p=0,037 (p=0,05) and correlation coefficient of 0,423. Conclusions: Physical activity and fast food consumption frequency have effects on overweight level in high school adolescent in Cirebon.
Pengaruh Kebiasaan Sarapan dan Perilaku Hidup Bersih Sehat terhadap Status Gizi Anak
Eni Suhaeni;
Uswatun Khasanah;
Catur Setiya Sulistiyana;
Dela Destiani Aji
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 7, No 2 (2021): TUNAS MEDIKA JURNAL KEDOKTERAN & KESEHATAN
Publisher : Tunas Medika Jurnal Kedokteran & Kesehatan
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Latar belakang: Status gizi adalah kondisi yang mencerminkan keseimbangan antara asupan zat gizi dari makanan dengan kebutuhan zat gizi yang diperlukan untuk metabolisme tubuh. Masalah kesehatan anak di Indonesia banyak disebabkan oleh status gizi. Beberapa upaya yang dapat dilakukan untuk memperbaiki status gizi anak adalah membiasakan sarapan dan perilaku hidup bersih dan sehat. Penelitian ini bertujuan untuk mengetahui besar pengaruh kebiasaan sarapan dan perilaku hidup bersih dan sehat terhadap status gizi Metode: Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional. Total responden sebanyak 180 anak kelas 1 sd 6 SD Jatisura Majalengka. Data status gizi diukur langsung berdasarkan berat badan dan tinggi badan, dan data lain diambil menggunakan kuestioner. Analisis data dilakukan menggunakan uji rank spearman. Hasil: Sebanyak 121 siswa (67,23 %) memiliki status gizi baik, 27 siswa (15,00%) kurus, dan 18 siswa (10%) obesitas. Data PHBS menunjukan bahwa 124 siswa (68,90%) memiliki kebiasaan PHBS yg baik dan hanya 2 siswa (1,1 %) buruk. Kebiasaan sarapan memiliki pengaruh yang signifikan dengan peningkatan status gizi (p=0001), sedangkan pengaruh PHBS secara statistik tidak signifikan (p=0.084) terhadap peningkatan status gizi anak. Simpulan: Kebiasaan sarapan yang baik mempengaruhi peningkatan status gizi anak.Kata kunci : Status gizi, Kebiasaan Sarapan, Perilaku Hidup Bersih Sehat (PHBS).
Hubungan antara Pengetahuan Seks Ibu Hamil terhadap Tingkat Kecemasan dalam Melakukan Hubungan Seksual di Puskesmas Sitopeng Kota Cirebon
Eni Suhaeni;
Wahyu Tri Utomo
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 1, No 3 (2014): Tunas Medika Jurnal Kedokteran & Kesehatan
Publisher : Tunas Medika Jurnal Kedokteran & Kesehatan
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Latar Belakang: Kebanyakan wanita hamil merasa takut dan khawatir untuk melakukan hubungan seksual, dikarenakan sebagian wanita hamil tidak mengetahui tentang posisi seks yang aman dan tidak aman selama kehamilan.Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui Hubungan Antara Pengetahuan Seks Ibu Hamil terhadap Tingkat Kecemasan dalam Melakukan Hubungan Seksual di Puskesmas Sitopeng Kota Cirebon.Metode: Jenis penelitian ini adalah Survei Analitik dengan metode pendekatan cross sectional. Populasi penelitian ini adalah semua ibu hamil yang memeriksakan kehamilannya di Puskesmas Sitopeng Kota Cirebon. Sampel yang diambil dalam penelitian ini sebanyak 40 orang ibu hamil pada bulan april hingga bulan mei tahun 2014. Teknik pengambilan sampel secara Accidental Sampling. Sedangkan untuk analisis datanya menggunakan uji Sperman’s Rank Correlation. Hasil: Hasil penelitian berdasarkan analisa uji statistik Spearman’s Rank Correlation didapatkan nilai sebesar -491** dengan arah negatif. Kedua variabel tersebut nilai P atau sig. Sebesar 0,001 atau lebih kecil dari tingkat kesalahan yang kita pasang P < 0,05 (5%). Menunjukkan bahwa semakin tinggi tingkat pengetahuan, maka akan semakin ringan tingkat kecemasan. Simpulan: Adanya hubungan yang signifikan antara pengetahuan seks ibu hamil dengan tingkat kecemasan dalam melakukan hubungan seksual.Kata kunci: Pengetahuan, Ibu hamil, Kecemasan, Hubungan seksual Background: Most pregnant women feel scared and worried to have sex, because most pregnant women do not know about safe sex positions during pregnancy and unsafe. Objective: The objective of this study was to determine the Relationship Between Pregnancy Sex Knowledge of the level of anxiety in sexual intercourse in the health center Sitopeng Cirebon. Methods: This research is Analytical Survey by cross sectional method. The study population was all pregnant women in health centers checkups Sitopeng Cirebon. Samples taken in this study were 40 pregnant women in April until the month of May 2014. Sampling technique accidental sampling. As for the analysis of data using Spearman's Rank Correlation test. Results: The results of statistical tests based on the analysis of Spearman's Rank Correlation obtained with a value of -491 ** negative direction. Both variables are because the P value or sig. Of 0.001 or smaller than the error rate that we put P < 0.05 (5%). Showed that the higher the level of knowledge, the more mild level of anxiety. Conclusions: There was a significant between maternal sexual knowledge with a level of anxiety in sexual intercourse.Keywords: Knowledge, Pregnant Women, Anxiety, Sexual Relations
EFFECT OF TREE MARIGOLD (Tithonia diversifolia (HEMSL.) A. GRAY) LEAVES INFUSION AND ETHANOL EXTRACT ON BLOOD GLUCOSE LEVEL AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED MALE WISTAR RATS
Rachma Ayu Maulidiany;
Eni Suhaeni;
Catur Setiya Sulistiyana;
Ariestya Indah Permata Sari
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
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Background: Common Indonesians often use alternative therapy for Diabetes Mellitus (DM) due to its high prevalence. Tree marigold (Tithonia difersivolia (Hemsl.) A. Gray) leaves show its positive effect in decreasing blood glucose level. Thus, it is important to analyze the negative effect of consuming the proposing alternative including its toxicity level to vital organs. This study aims to observe the blood glucose level and liver histopathology in streptozotocin-induced diabetic male rats treated by infusion and ethanol extract of the tree marigold leaves. Methods: Pretest and posttest with control group design experiment was conducted to analyze effect on blood glucose level and posttest only with control group design was for determining liver histopathology. Twenty-four male white rats (Wistar strain) were randomly divided into 4 groups: normal control group (KN), positive control group (K+) treated with 0.45mg/kg of glibenclamid, treatment group 1 (P1) treated by 100 mg/kg of tree marigold leaves ethanol extract, and treatment group 2 (P2) treated by 1373 mg/kg of tree marigold leaves infusion. The rats at the groups of K+, P1, and P2 were induced by streptozotocin to reach hyperglycemic state. Comparison of blood glucose level effect between infusion and ethanol extract was analyzed by One-Way ANOVA continued by post-hoc test, while comparison of liver histopathology effect was determined by Kruskal-Wallis continued by Mann-Whitney test. Results: Significant differences of blood glucose level decrease were found in all groups. Group P2 significantly decreased blood glucose level more than P1 (p=0.000) as much as 124.97 mg/dl and 101.46 mg/dl respectively. Significant differences of liver histopathology were obtained between KN vs K(+), KN vs P2, K(+) vs P2, and P1 vs P2. Group P2 showed more severe of liver histopathology changes than P1 (p=0.025). Conclusion: Tree marigold leaves extract is more effective in lowering blood glucose level and has less toxic effect to liver histopathology than its infusion.
EFFECT OF PHYSICAL ACTIVITY AND FAST FOOD CONSUMPTION FREQUENCY ON OVERWEIGHT LEVEL AMONG HIGH SCHOOL ADOLESCENT
Lita Harlianti;
Witri Pratiwi;
Donny Nauphar;
Eni Suhaeni
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
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Background: Obesity was believed to be one of the risk factors of degenerative diseases, such as diabetes mellitus, hypertension, and coronary heart disease. Obesity occurred gradually that started with overweight. Risk factors for overweight are lack of physical activity, and consumption of high caloric fatty food which may cause accumulation of fats inside the body. This research aims to examine the effect of physical activity and fast food consumption frequency on overweight level among high school adolescent in Cirebon. Methods: It was a cross-sectional study conducted among 262 high school students aged 15-17 years using stratified random sampling. Results: The result based on Spearman correlation test showed negative correlation between physical activity and overweight level with p= 0,001 (p< 0,05) and correlation coefficient of -0,627. There was positive correlation between consumption fast food frequency with overweight with p=0,037 (p=0,05) and correlation coefficient of 0,423. Conclusions: Physical activity and fast food consumption frequency have effects on overweight level in high school adolescent in Cirebon.
CALCULATING COLONY OF Candida spp. AMONG CHILDREN WITH INTELLECTUAL DISABILITY IN CIREBON
Dhini Oktaviani;
Amanah Amanah;
Eni Suhaeni;
Risnandya Primanagara
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
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Background: Children and adults with Intellectual Disability and Autism Spectrum Disorders (ASD) have decreased intestinal permeability and enzyme activity, causing gastrointestinal (GI) problems that are more frequent and more severe than in children from the general population. The immune system which is part of the intestinal barrier in children with Intellectual Disability (ID) experiences various disorders and becomes more susceptible to fungal invasion, such as Candida spp. This present study aims to calculate the colony of Candida spp. in the digestive tract of Children with Intellectual Disability (ID) in the city of Cirebon.Method: This is an observational study with cross-sectional design using purposive sampling. The study was conducted in November 2018-February 2019. The sample (ID) group consists of 31 individuals from Special Needs School and 60 individuals from National elementary school (non-ID) in the city of Cirebon. The inclusion criteria were children ages 6-12 years and the exclusion criteria were children under antifungal treatment and children under cytotoxic or immunosuppressive drugs. The fecal samples from the ID group and non-ID were examined at the Laboratory of the Faculty of Medicine, Universitas Swadaya Gunung Jati Cirebon, Indonesia using Digital Colony counter. Collected data were stored and analyzed using computer aided Statistical program. Mann-Whitney analysis of variance techniques were used to test the hypotheses. Results: The results showed that there are significant differences in the colonies of Candida spp. between the ID group and non-ID group. Median colony of Candida spp. in the ID group is 39.00 with mean colony of 126.90 while the median colony of non-ID group is 3.00 with mean colony of 40.93 (p<0.001).Conclusion: There are significant differences between the Candida spp. colonies in the ID group with the non-ID.
CALCULATING COLONY OF Candida spp. AMONG CHILDREN WITH INTELLECTUAL DISABILITY IN CIREBON
Dhini Oktaviani;
Amanah Amanah;
Eni Suhaeni;
Risnandya Primanagara
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
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Background: Children and adults with Intellectual Disability and Autism Spectrum Disorders (ASD) have decreased intestinal permeability and enzyme activity, causing gastrointestinal (GI) problems that are more frequent and more severe than in children from the general population. The immune system which is part of the intestinal barrier in children with Intellectual Disability (ID) experiences various disorders and becomes more susceptible to fungal invasion, such as Candida spp. This present studyaims to calculate the colony of Candida spp. in the digestive tract of Children with Intellectual Disability (ID) in the city of Cirebon. Method: This is an observational study with cross-sectional design using purposive sampling. The study was conducted in November 2018-February 2019. The sample (ID) group consists of 31 individuals from Special Needs School and 60 individuals from National elementary school (non-ID) in the city of Cirebon. The inclusion criteria were children ages 6-12 years and the exclusion criteria were children under antifungal treatment and children under cytotoxic or immunosuppressive drugs. The fecalsamples from the ID group and non-ID were examined at the Laboratory of the Faculty of Medicine, Universitas Swadaya Gunung Jati Cirebon, Indonesia using Digital Colony counter. Collected data were stored and analyzed using computer aided Statistical program. Mann-Whitney analysis of variance techniques were used to test the hypotheses. Results: The results showed that there are significant differences in the colonies of Candida spp. between the ID group and non-ID group. Median colony of Candida spp. in the ID group is 39.00 with mean colony of 126.90 while the median colony of non-ID group is 3.00 with mean colony of 40.93(p<0.001). Conclusion: There are significant differences between the Candida spp. colonies in the ID group with the non-ID. Keywords: Intellectual Disability (ID), Candida spp., Gastrointestinal
EFFECT OF TREE MARIGOLD (Tithonia diversifolia (HEMSL.) A. GRAY) LEAVES INFUSION AND ETHANOL EXTRACT ON BLOOD GLUCOSE LEVEL AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED MALE WISTAR RATS
Rachma Ayu Maulidiany;
Eni Suhaeni;
Catur Setiya Sulistiyana;
Ariestya Indah Permata Sari
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
Show Abstract
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Download Original
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Background: Common Indonesians often use alternative therapy for Diabetes Mellitus (DM) due to its high prevalence. Tree marigold (Tithonia difersivolia (Hemsl.) A. Gray) leaves show its positive effect in decreasing blood glucose level. Thus, it is important to analyze the negative effect of consuming the proposing alternative including its toxicity level to vital organs. This study aims to observe the blood glucose level and liver histopathology in streptozotocin-induced diabetic male rats treated by infusion and ethanol extract of the tree marigold leaves. Methods: Pretest and posttest with control group design experiment was conducted to analyze effect on blood glucose level and posttest only with control group design was for determining liver histopathology. Twenty-four male white rats (Wistar strain) were randomly divided into 4 groups: normal control group (KN), positive control group (K+) treated with 0.45mg/kg of glibenclamid,treatment group 1 (P1) treated by 100 mg/kg of tree marigold leaves ethanol extract, and treatment group 2 (P2) treated by 1373 mg/kg of tree marigold leaves infusion. The rats at the groups of K+, P1, and P2 were induced by streptozotocin to reach hyperglycemic state. Comparison of blood glucose level effect between infusion and ethanol extract was analyzed by One-Way ANOVA continued by post-hoc test, while comparison of liver histopathology effect was determined by Kruskal-Wallis continued byMann-Whitney test. Results: Significant differences of blood glucose level decrease were found in all groups. Group P2 significantly decreased blood glucose level more than P1 (p=0.000) as much as 124.97 mg/dl and 101.46 mg/dl respectively. Significant differences of liver histopathology were obtained between KN vs K(+), KN vs P2, K(+) vs P2, and P1 vs P2. Group P2 showed more severe of liver histopathology changes than P1 (p=0.025). Conclusion: Tree marigold leaves extract is more effective in lowering blood glucose level and has less toxic effect to liver histopathology than its infusion.