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Journal : Pharmacon

Studi Penggunaan Obat Anti Tuberkulosis (OAT) Tahap Lanjutan pada Pasien Baru BTA Positif Tista Ayu Fortuna; Hidajah Rachmawati; Didik Hasmono; Hidayah Karuniawati
Pharmacon: Jurnal Farmasi Indonesia Vol 19, No 1 (2022)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v19i1.17907

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Tuberculosis will cause pain and death if not treated properly. OAT (Antituberculosis Drugs) is a treatment for tuberculosis patients. OAT has different dosage regimens and types of drugs. Treatment of TB patients consists of two phases (intensive and continuation phases). The continuation phase was at to kill dormant bacteria to prevent recurrence in patients. The purpose of this study was to determine and evaluate the pattern of using OAT in patients newly diagnosed rwith smear-positive at the continuation phase. This study is an observational descriptive study with results showing that the pattern of using OAT-KDT in patients was 89% and OAT-Separated was 11%. The pattern of using the OAT-KDT dose was 1x3 2KDT tablets. Another combination of antibiotics given to the patient is cotrimoxazole at a dose of 1x960mg. The side effect of OAT is an increase in serum transaminase and nausea each with a percentage of 23%. Based on the research, it can be concluded that the pattern of using OAT in Tuberculosis patients has followed the guidelines for the management of Tuberculosis treatment.
Faktor – Faktor yang Mempengaruhi Komplikasi pada Pasien Diabetes Mellitus di RSUD Dr. Moewardi Tista Ayu Fortuna; Hidayah Karuniawati; Desti Purnamasari; Devi Etivia Purlinda
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 1 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i1.21877

Abstract

Diabetes Mellitus (DM) is a disease characterized by hyperglycemia and disturbances in the metabolism of carbohydrates, fats, and proteins associated with absolute or relative deficiencies of insulin action and or secretion. The main problem for DM sufferers is that more than 50% of diabetic patients do not know about the disease and its complications, so patients will return to the hospital with high blood glucose levels accompanied by various complications. The study aims to determine the factors that can cause complications in patients with diabetes mellitus. This research is a non-experimental study with a cross-sectional approach. The data were analyzed using SPSS with a Chi-square or Kruskal-Wallis and multivariate logistic regression test. Body mass index and duration of diabetes are significantly associated with the incidence of complications (p-value 0.05). Patients with an abnormal body mass index are 4.184x more at risk of complications than patients with a normal body mass index (RR 4.184 CI 1.581 – 11.070). In addition, patients with diabetes duration ≥5 years were 4.121 times more at risk of complications than patients with diabetes durations 5 years (RR 4.121 CI 1.570 – 10.816). The most common complication suffered by diabetic patients in this study was hypertension in 46 patients (41%), and the most common therapeutic regimen received by patients was oral hypoglycemia in 50 patients (52%). 
Direct benefits of Covid-19 Vaccination at Juata Primary Health Center, North Tarakan District Harlianti, Mariska Sri; Fortuna, Tista Ayu; Ramadhini, Affida; Aisya, Fitria Shofwa
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 2 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i2.23306

Abstract

North Kalimantan Province is the only province with a pandemic situation level in the medium level community transmission (CT2) category with an accumulated incidence of 24.1 per 100,000 population in 2021. The increasing incidence is accompanied by opinions of rejection in the community regarding confusion over Covid-19 vaccination at the start of the incident. , underlying the increasing morbidity and mortality rates as well as the decline in the country's social and economic activities. The Covid-19 vaccination program is an effort to reduce morbidity and mortality rates as well as restore social and economic conditions due to the pandemic. The aim of this research is to calculate the direct economic value of the Covid-19 vaccination program. Observational research with descriptive quantitative data analysis was carried out to illustrate this aim. Data collection was carried out retrospectively based on monthly reports from the Juata Community Health Center specifically for Covid-19. The sample inclusion criteria in this study were data on patients who were confirmed positive for Covid-19 in the North Tarakan District area in 2020 – 2022 and received therapy based on the guidelines or Guidelines for the management of Covid-19, 4th edition of 2022. The sample was divided into 3 vaccination periods with the number of samples for each were 77, 92, and 89 patients respectively. The direct benefit of the Covid-19 vaccination program is the difference in total costs between periods. The research results show that the difference in costs for periods I and II and II and III is negative, namely (-) IDR 12,697,280 and (-) IDR 494,660, respectively. Thus, from an economic aspect it does not yet illustrate the direct benefits of the 1 – 3 dose vaccination program. One of the reasons may be the inappropriate use of Covid-19 treatment drugs, namely oseltamivir. However, the incidence of Covid-19 decreased by 34.8% in period III (vaccination doses 2 to 3), namely 417. This shows that from a clinical aspect, the Covid-19 vaccination program is able to increase immunity.
Co-Authors A Anifatussaa'dah Adedhea, Marchita Aflit Nuryulia Praswati Ahmad, Farhand Aisya, Fitria Shofwa Andi Suhendi Andriyani, Refi Anifatussaa'dah, A Ardalia Rinanda Oktaviani Arifah Sri Wahyuni Ariyanti, Rika Astuti, Dina Yuli Auliya, Dhiyahul Azzah, Millenia Syafirah Yunita Basusena, Rahardian Surya Broto Santoso Burhanudin Ichsan Citra, Tia Mella Desti Purnamasari Devi Etivia Purlinda Dewi, Triana Ariska Didik Hasmono Dwi Sarbini Dzafira, Laila Erna Herawati Erna Herawati, Erna Faghfirlie, Faghfirlie Fahriza Mei Trihatmoko Faridita khoirun Nisa' Fidhia Nur Rifaini Firdani, Tamza Aulia Nerisa Fita Rahmawati Fitriani, Rizki Ainun Haliza Arzeti Nurseptiria Haryoto Haryoto Haryoto, H Haya Nabilah Utama HI, Marsilia Rosa Sinensis Hidajah Rachmawati Hidaya, Anggi Fajriatu Hidayah Karuniawati Ichsan, Burhanudin Ida Maesaroh Ida Maesaroh, Ida Keisya, Aulita Khusnul Khotimah khusnul khotimah Kusumastuti, Lina Ayu Laila Dzafira Lina Ayu Kusumastuti Listiana Masyita Dewi Maharani, Suciana Mariska Sri Harlianti Marisya Affifah Putri, Nabilla Marsilia Rosa Sinensis HI Marsya, Vitania Mubarok, Afrizal Mudhofir, Nisrina Salsabila Muhtadi Muhtadi Muhtadi, M Mulyani, Amelia Sri Muslihah, Sayyidah Nurul Nabilla Marisya Affifah Putri Nadya Tiara Putri Nanang Munif Yasin Nanang Munif Yasin Ni Nyoman Yudianti Mendra Nikita, Aulia Bea Nisa', Faridita khoirun Nuraini, Davina Lathifah Nuraini, Filla Rizky Nurseptiria, Haliza Arzeti Oktaviani, Ardalia Rinanda Prabowo, Alifia Istiqomah Prehanawan, Refian Putra Raafika Studiviani Rahardian Surya Basusena Rahmawati, Fita Ramadhini, Affida Rayidah, Tasya Refi Andriyani Renatasari, Distya Ayu Rifaini, Fidhia Nur Riskiana, Shafira Yuni Rizki Ainun Fitriani Safitri, Aisyah Nur Salsabila, Nandifa Azzahra Saputri, Gafrila Fani Eka Sarif, Nabil Nawal Sasmitha, Desya Sayyidah Nurul Muslihah Sri Kusuma Dewi, Sri Kusuma Studiviani, Raafika Sulistyani Sulistyani Syahidah, Shofia Rif'atusy Tanti Azizah Sujono Tia Mella Citra Trihatmoko, Fahriza Mei Utama, Haya Nabilah Utami , Anita Dwi Utari, Berlian Vitania Marsya Yudianti Mendra, Ni Nyoman