Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

Aktivitas Antiseptik Lotion Kombinasi Ekstrak Herbal Pegagan (Centella Asiatica (L.) Urban Dan Aloe Vera Terhadap Bakteri Pseudomonas Aeruginosa Delladari Mayefis; Rury Trisa Utami
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 3 (2021): NOVEMBER : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i3.2931

Abstract

Pseudomonas aeruginosa is a bacterium that can cause a variety of diseases, one of which is an infection with the skin. Where one of the ways to prevent infections of the skin is by hand washing, one of them uses antiseptic. The study aims to test the antibacterial ativity of the gel antiseptic, a combination of Centella Asiatica extract and aloe vera extract against Pseudomonas aeruginosabacteria. This research uses a method of diffuse diffusion with the concentration of a combination of Centella asiatica and Aloe vera extract is 5%: 5% (f IV), 7.5%: 2.5% (f V), 7.5%: 2.5% (f VI), with positive control using an antiseptic antic. Antibacterial activity with an antiseptic combination of Centella Asiatica herbal extract and aloe vera against Pseudomonas aeruginosa bacteria has a moderate-to-medium catfisher inhibition of 18.06 mm. Based on statistical tests using ANOVA indicates there is a significant difference between the average percentage value between groups (sig ≤ 0.05).
Uji Efek Stimulan Sistem Saraf Pusat Dari Ekstrak Etanol Biji Pala (Myristica fragrans H.) Pada Mencit Putih Jantan Delladari Mayefis; Shinta Sari Dewi; Nurlia Oktaviyanti; Arie Vonikartika
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 2 (2021): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i2.2943

Abstract

Research on the effects of central nervous system stimulants from nutmeg (Myristica Fragrans H.) ethanol extract on male white mice has been carried out using the methods of: sleep onset test, hanging test, swimming test, and evacuation test. In this study, the test animals were divided into five groups in which each group consisted of three animals for three experiments, the first group was given a 0.5% NaC CMC suspention, the next three groups were given extracts of nutmeg seed ethanol (Myristica Fragrans H. ) with three variations of doses, namely 150, 300, and 600 mg / Kg BW, the next group as a comparison was given a caffeine solution of 13 mg / kg BW. Each preparation was given orally and then carried out a observation of several test methods. The results showed that the ethanol extract of nutmeg (Pala H.) can provide a good stimulant effect at a dose of 300 mg / kg BW (p <0.05) which was clearly seen in the swimming test and the hanging test method.