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All Journal International Journal of Public Health Science (IJPHS) Reaktor JURNAL GIZI INDONESIA Journal of Nutrition College Jurnal Kesehatan Masyarakat Medical Journal of Indonesia Journal of Biomedicine and Translational Research Paediatrica Indonesiana GIZI INDONESIA AcTion: Aceh Nutrition Journal Jurnal Aisyah : Jurnal Ilmu Kesehatan
Mohammad Sulchan
Department Of Nutrition, University Of Diponegoro Medical Faculty
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : JURNAL GIZI INDONESIA

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Kadar seng dan kadar malondialdehyde pada penderita multi drug resistant tuberculosis dan tuberkulosis sensitif Suparno, Suparno; Suhartono, Suhartono; Sofro, Muchlis Achsan Udji; Sulchan, Mohammad; Tjahjono, Kusmiyati
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.743 KB) | DOI: 10.14710/jgi.7.1.8-14

Abstract

Background: Zinc is the main constituent element of Superoxide Dismutase (SOD) which acts to protect cells from inflammation and the toxic effects of Reactive Oxygen Species (ROS). High ROS production induces fat peroxidation, and forms malondialdehyde (MDA) which causes oxidative stress.Objectives: This study aimed to analyze the difference of zinc and malondialdehyde levels among Multi Drug Resistant Tuberculosis and sensitive Tuberculosis.Methods: Crossectional study with 55 subjects consisted of 32 MDR-TB subjects and 23 subjects TB sensitive. Selection of subjects using consecutive sampling. Zinc and MDA serum was obtained from venous blood. Zinc and MDA concentration were assessed by quantitative colometric and Thiobarbituric Acid Reactive Substances (TBARS) respectively. Data were analized statistic by independent t-test and Mann Whitney test.Results: Zinc level of MDR-TB and TB sensitive were 74.85 (64 - 97) μg/dl and 73.03 (63 - 97) μg/dl respectively, while MDA of MDR-TB and sensitive TB were 2.262±1.055 nmol/mL and 2.66±0.992 nmol/mL. There was no significantly different in zinc level between MDR-TB and sensitive TB (p=1.000). Furthermore, there was not significantly different of MDA level between MDR-TB and sensitive Tuberculosis (p=0,147).Conclusion: There are no differences in zinc and MDA levels in patient between MDR-TB and sensitive TB.
Sensitivitas dan spesifisitas lingkar pergelangan tangan sebagai prediktor obesitas dan resistensi insulin pada remaja akhir Fitriyanti, Addina Rizky; Tjahjono, Kusmiyati; Sulchan, Mohammad; Sunarto, Sunarto
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 2 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.753 KB) | DOI: 10.14710/jgi.7.2.121-126

Abstract

Background: Obesity is one of the risk factors for insulin resistance. Insulin resistance plays an important role in the pathogenesis of cardiovascular disease. Wrist circumference has the potential for predicting obesity and insulin resistance.Objectives:. To evaluate the sensitivity and specificity of wrist circumference against obesity and insulin resistance in late adolescents.Methods: The design of this study is a crossectional study with a sample of 85 students at Diponegoro University Semarang. Data collected consisted of anthropometric measurements (body weight, height, wrist circumference, neck circumference, waist circumference and pelvic girth) and blood vein sampling (fasting blood glucose and fasting insulin). Statistical analyses used in this study were Pearson or R Spearman correlation test.Results: Wrist circumference was positively correlated with all biochemical parameters and anthropometric measurements except the waist hip ratio. Wrist circumference correlates positively and significantly with fasting insulin and HOMA-IR in male adolescents. The results of the ROC curve analysis showed that the AUC value of wrist circumference in male adolescents had better performance in predicting obesity (88% (95% CI, 76% - 100%)) than insulin resistance (81% (95% CI, 51% -100%)).Conclusion: Wrist circumference is one of the anthropometric measurements that can be used for predicting obesity and insulin resistance in late adolescents.
Exploring rice varietal effects on triglyceride/high density lipoprotein ratio in hyperlipidemia-induced wistar rats Rosmalinda, Yusie; Noer, Etika Ratna; Sulchan, Mohammad; Khikmaturrohman, Sya’bani Isnaen; Ardiaria, Martha; Marsa, Firdaus Shadiqa; Henny, Via Anugrah; Wijayanti, Hartanti Sandi; Panunggal, Binar
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.170-181

Abstract

Background: Excessive intake of white rice has been associated with elevated triglyceride (TG) levels and decreased high density lipoprotein (HDL) cholesterol concentrations. Conversely, black and red rice varieties have demonstrated favorable impacts on lipid metabolism. However, despite these benefits, their palatability and texture are often met with aversion by consumers. Consequently, it is imperative to investigate rice blends that are both well-received by individuals and exhibit pronounced efficacy in reducing the TG/HDL ratio.Objective: To investigate the differential effects on the TG/HDL ratio in rats administered different combinations of white, red, and black rice.Methods: This research follows a true experimental design incorporating pre- and post-tests with a control group. Thirty rats were initially fed a hyperlipidemic diet for 14 days. Subsequently, the rats were subjected to interventions involving different rice combinations for a duration of 28 days. These combinations included K(+) (positive control), P1 (100% white rice), P2 (21 g red and 4 g white rice), P3 (16 g black and 4 g white rice), and P4 (8 g black, 8 g red, and 4 g white rice). Triglyceride and HDL levels were quantified using the GPO-PAP and CHOD-PAP methods, respectively. Statistical analysis was performed utilizing ANOVA tests followed by LSD post-hoc tests for comparison.Results: Triglycerides decrease in P4 (-51.04±0.72) was the highest, followed by P3 (47.18±0.51), P2 (-34.60±1.07), P1 (-17.03±1, 06). Cholesterol HDL increase in P4 (49.36±1.68) was the highest, followed by P3 (42.71±0.41), P2 (38.09±0.76), P1 (30.64±0.90). The TG/HDL ratio in P1, P2, P3, and P4 were 0.21±0.092, -2.12±0.164, -2.45±0.123, -2.82±0.148, -3.18±0.371, respectively. The rice combination intervention had a significant decreased on the TG/HDL ratio (p=0.000).Conclusion: The intervention involving rice combinations resulted in a greater reduction in the TG/HDL ratio compared to the consumption of white rice alone. Among the various combinations tested, the combination of white, red, and black rice demonstrated the most significant reduction in the triglyceride to HDL-cholesterol (TG/HDL) ratio.
Co-Authors Adriyan Pramono Agustina L.N. Aminin Alifiati Fitrikasari Anak Agung Gede Sugianthara Anjani, Gemala Ari Yulistianingsih Bambang Pramudono Banundari Rachmawati Banundari Rahmawati Binar Panunggal Dewi, Luthfia Diana Nur Afifah, Diana Nur Dyah Ayu Kresnianingrum Etika Ratna Noer Fitriyanti, Addina Rizky Gunawan, I Putu Gde Fredy Hartanti Sandi Wijayanti Henny, Via Anugrah Innawati Jusup Khikmaturrohman, Sya’bani Isnaen Kusmiyati Tjahjono Luthfi Kurnia Dewi Mambaya, Helvi Desi Marsa, Firdaus Shadiqa MARTHA ARDIARIA MG I. Rukmi Muchlis Achsan Udji Sofro Muniroh, Muflihatul Natalia Dewi Wardani Nur Rokhati Ponco Birowo Rimadhani Ulfa Rosmalinda, Yusie Rosyida Awalia Safitri Satoto Satoto Selanno, Fradelino Esau Shofa Chasani Sunarti Sunarti Sunarti Sunarto Sunarto Suparno Suparno Tanjung Ayu Sumekar Taufik Maryusman Titik Istirokhatun Titis Hadiati Tjahjono, Kusmiyati DK Tri Indah Winarni Yusuf Hidayat Zulfikar Ali, Zulfikar