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Rahayu, Yanti
Program Studi Teknologi Laboratorium Medik, STIKes Syedza Saintika
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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PENYULUHAN DAN EDUKASI TENTANG PENYAKIT HIPERTENSI Arniat Christiani Telaumbanua; Yanti Rahayu
Jurnal Abdimas Saintika Vol 3, No 1 (2021): Mei Jurnal Abdimas Saintika
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jas.v3i1.1069

Abstract

ABSTRAK Hipertensi adalah kenaikan tekanan darah baik sitolik maupun diastolic. Hipertensi di kenal dengan the heterogeneous group of disease dan the killer diasease. Hipertensi merupakan factor risiko yang menyebabkan kematian dini, serta terjadinya gagal jantung dan penyakit gangguan otak. Data WHO tahun 2015 menunjukkan sekitar 1,13 miliar orang di dunia menyandang hipertensi, yang berarti 1 dari 3 orang di dunia terdiagnosis hipertensi. Jumlah ini akan terus meningkat setiap tahunnya, diperkirakan pada tahun 2025 akan ada 1,5 miliar orang yang terkena hipertensi,  menurut perkiraan ada 10,44 juta orang akan meninggal akibat hipertensi dan komplikasinya di setiap tahun. Factor usia, sosial dan ekonomi dapat terserang hitertensi. Dengan bertambahnya usia, risiko hipertensi menjadi lebih besar, ini disebabkan adanya perubahan strukur pada pembuluh darah besar sehingga lumen menjadi sempit dan dinding pembuluh darah menjadi lebih kaku dan tekanan darah sistolik meningkat. Tujuan pengabdian masyarakat ini untuk memberikan penyuluhan dan mengedukasi masyarakat tentang penyakit hipertensi. Metode yang dilakukan dengan mengunjungi serta memberikan edukasi di sertai diskusi kepada masyarakat dan melakukan pemeriksaan tekanan darah. Pengabdian masyarat ini dilakukan pada tanggal 9, 10 13 dan 23 Januari 2021di kecamatan bungus teluk kabung. Dengan memberi penyuluhan tentang penyakit hipertensi , memberi brosur untuk mengedukasi masyarakat serta melakukan pemeriksaan tensi.  Kata Kunci: edukasi, penyuluhan , hipertensi  ABSTRACTHypertension is increasing and diastolic blood pressure both sitolik.Hypertension in know the heterogeneous group of disease and the killer diasease.Hypertension is a risk of causing, early death and the occurrence of heart failure. brain disorders and diseasesThe who data years 2015 1,13 demonstrated about billion people around the world bears, hypertension which means 1 3 people around the world from an undiagnosed. hypertensionThis number will continue to increase annually, it is estimated that in 2025 1,5 there will be billion people affected, hypertension and according to estimates there are million who will 10,44 died of hypertension and komplikasinya. in every yearOf, age social and economic hitertensi. can developWith age, the risk of hypertension is greater, is due to the change strukur on the veins of the large lumen become narrower in the walls of veins and become more rigid and. increase systolic blood pressure. The purpose of this community devotion to provide counseling and educate people about disease hypertension .A method that done by visiting and give education in sertai discussion to the people and to check blood pressure .Devotion masyarat is done on june 9 , 10 and 13 in 23 january 2021di bungus kabung bay .To provide information about diseases hypertension , give brochures to educate the people and have a tension .  Keywords: education , counseling , hypertension
EFEKTIVITAS BAKTERI Pseudomonas fluorescens SEBAGAI PENYERAP LOGAM KADMIUM PADA LEACHATE TEMPAT PEMBUANGAN AKHIR SAMPAH AIR DINGIN Yanti Rahayu; Dina Putri Mayaserly; Corry Handayani
Jurnal Kesehatan Saintika Meditory Vol 2, No 2 (2020): Mei 2020
Publisher : Stikes Syedza Saintika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jsm.v2i2.532

Abstract

ABSTRAKSampah menjadi masalah yang serius dikota-kota besar maupun daerah tetapi  perkembangan pengelolaan sampah tidak sebanding dengan laju  timbunan sampah yang akan mengalami proses dekomposisi yang ditandai dengan perubahan fisis, biologis dan kimiawi. Bahan organik  pada sampah mengalami dekomposisi menghasilkan leachate.. Bahan organik dan logam berat  terutama logam Cd yang terdapat dalam limbah dapat dikurangi menggunakan bakteri Pseudomonas fluorescens pada skala laboratorium. bakteri yang digunakan merupakan salah satu bakteri sebagai penyerap logam Cd dalam leachate yang terdapat di TPA Air Dingin. Parameter  yang diuji adalah kemampuan daya penyerapan optimal pada logam Cd oleh Leachate.  Penelitian ini dilakukan dengan kerapatan  0,5×108 /ml optimal daya serap 41,622 % , 1×108 /ml optimal daya serap 55,202 %, 2×108 /ml optimal daya serap 59,082 %, 3×108 /ml optimal daya serap 66,313 % dan 4×108 /ml optimal daya serap 72,045 % dan dari hasil penelitian yang dilakukan pada Leachate oleh bakteri Speudomonas fluorescens efektif dalam menyerap logam Cd.
KORELASI KADAR MAGNESIUM TERHADAP KADAR VITAMIN D PADA PASIEN COVID-19 Eliza Arman; Kurnia Safitri; Yanti Rahayu
Jurnal Kesehatan Medika Saintika Vol 13, No 2 (2022): Desember 2022
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v13i2.1684

Abstract

ABSTRAKSARS-CoV-2, virus penyebab coronavirus disease 2019 (COVID-19) merupakan penyakit pneumonia penyebab pandemi tahun 2020. Status vitamin D dapat memengaruhi risiko kematian akibat SARS-CoV-2. Vitamin D juga dikonsumsi bagi penderita terkonfirmasi SarCov-2 karena vitamin D baik untuk metabolisme dan dapat meningkatkan daya tahan tubuh. Magnesium adalah kofaktor dalam lebih dari 300 sistem enzim yang mengatur reaksi biokimia yang beragam dalam tubuh, termasuk sintesis protein, untuk otot dan fungsi saraf, mengatur kadar glukosa darah, dan regulasi tekanan darah. Magnesium juga mempengaruhi konsentrasi dari kedua hormon paratiroid dan untuk mengaktifkan pembentukan vitamin D. Tujuan penelitian ini adalah untuk mengetahui kadar rata-rata Magnesium dan Vitamin D, serta korelasi kadar Magnesium terhadap kadar vitamin D pada Pasien COVID-19. Penelitian ini merupakan penelitian observasional analitik dengan desain penelitian pendekatan retrospektif  dilakukan pada bulan Maret – Juni 2022  di Laboratorium Klinik Prodia Padang. Hasil penelitian didapatkan kadar Magnesium sampel rata-rata adalah sebesar 2,14 mg/dL dengan nilai standar deviasi sebesar 0,15, sedangkan kadar Vitamin D sampel rata-rata adalah sebesar 26,81 ng/mL dengan nilai standar deviasi sebesar 8,14. Terdapat korelasi berkekuatan sedang antara kadar Magnesium dengan kadar Vitamin D pada pasien COVID-19 berdasarkan uji korelasi Pearson dengan nilai p = 0,003 < α 0,005, sedangkan nilai r nya adalah 0,436
Uji Aktivitas Antibakteri Virgin Coconut Oil (VCO) terhadap Pertumbuhan Bakteri Staphylococcus aureus Niken Niken; Rahmi Novita Yusuf; Yanti Rahayu; Ibrahim Ibrahim
Bioscientist : Jurnal Ilmiah Biologi Vol 11, No 1 (2023): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v11i1.7244

Abstract

Infectious disease is a disease that is generally caused by infection with pathogenic microorganisms. Staphylococcus aureus is a bacterium that causes the most common infectious disease. S. aureus infects tissues or organs and can cause disease which has characteristic signs of inflammation, necrosis, and abscess formation. Generally treat this Staphylococcus aureus bacterial infection by administering antibiotics. Long-term administration of antibiotics can cause negative effects on the body. One of the efforts to control S. aureus bacterial infection is by using herbal ingredients. VCO contains medium chain saturated fatty acids (Medium Chain Fatty Acid). Medium Chain Fatty Acid, namely lauric acid which can be broken down into monolaurin which has antibacterial properties. This study aims to determine whether VCO can inhibit the growth of S. aureus bacteria. This research is a laboratory experiment using the paper disc diffusion method (Kirby-Bauer). The sample used is Staphylococcus aureus bacteria. The concentrations used in this study were 20%, 40%, 60%, 80%, 100% and amoxicillin positive control and DMSO negative control. Data analysis was performed statistically with the One-Way Analysis of Variance (ANOVA) test. Data is normally distributed and homogeneous. The results showed that the antibacterial activity of VCO was shown to have inhibition against S. aureus bacteria with an average concentration of 20% with a diameter of 14.4 mm (strong), 40% diameter 14.5 mm (strong), 60% diameter 14.6 mm (strong), 80% diameter 14.6 mm (strong), 100% diameter 16.0 mm (strong), positive control amoxicillin 7.9 mm and negative control 0 mm. The results of the ANOVA test showed a value of p = 0.000 (sig. < 0.05) that there was a significant difference between all treatments with a positive control. It can be concluded that VCO was effective in inhibiting the growth of S. aureus bacteria, this was because the diameter of the VCO inhibition zone was larger than the positive control.
INDENTIFIKASI PROTOZOA USUS PADA ANAK DI KELURAHAN PASIE NAN TIGO KECAMATAN KOTO TANGAH KOTA PADANG rahayu, yanti; Niken, ,
E-Jurnal Medika Udayana Vol 12 No 10 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i10.P11

Abstract

Infeksi protozoa usus masih menjadi masalah kesehatan utama pada anak-anak, karena anak-anak paling sering berkontak dengan tanah sebagai sumber infeksi dan merupakan ancaman yang signifikan, namun sering diabaikan terhadap kesehatan masyarakat sampai komplikasi parah atau kronis karena banyak dari mereka biasanya tanpa gejala atau hanya bermanifestasi gejala ringan saja. Tujuan penelitian ini yaitu untuk mengetahui angka kejadian infeksi protozoa usus pada anak di Kelurahan Pasie Nan Tigo Kecamatan Koto Tangah Kota Padang. Jenis penelitian ini adalah deskriptif kategorik, sampel berupa data primer dengan jumlah sampel 64 anak menggunakan teknik consecutive sampling. Penelitian ini dianalisis univariat dan disajikan dalam bentuk tabel distribusi frekuensi. Penelitian ini didapatkan hasil infeksi protozoa usus pada anak yang ditemukan Cyclospora Cayetanensis sebesar 63,6% dan Blastocyctis Hominis 36,4%. Infeksi protozoa usus lebih tinggi pada kelompok umur 5-9 tahun 31,0% dan lebih tinggi pada anak perempuan 37,1 %. Simpulan penelitian ini didapatkan bahwa angka kejadian infeksi protozoa usus cukup tinggi pada anak di Kelurahan Pasie Nan Tigo Kecamatan Koto Tangah Kota Padang. Oleh karena itu, anak-anak tersebut perlu mendapatkan perhatian khusus, dan dilakukan pengobatan secepatnya pada anak-anak yang terinfeksi serta penyuluhan mengenai edukasi dan pencegahan penyakit akibat protozoa usus. Kata kunci : Protozoa usus., C. Cayetanensis., Anak-anak
RANCANG BANGUN PROTOTYPE SISTEM E-ARSIP PEMBIAYAAN KPR BERBASIS WEB PADA PT BANK SYARIAH INDONESIA KCP BEKASI TIMUR -, Satria; Rahayu, Yanti; Agung, Rudi Budi; -, Marisa
JTIKA (Jurnal Teknik Informatika, Komputer dan Aplikasinya) Vol 6 No 1 (2024): March 2024
Publisher : Program Studi Teknik Informatika, Fakultas Teknik, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jtika.v6i1.357

Abstract

BSI is one of the banks that still uses a manual KPR financing data archiving system. The problem that occurs at BSI, especially the Bekasi branch, is that requests for financing copies take 14 working days or even longer. Therefore, the information system for archiving KPR financing documents at BSI, which was initially still manual, has become a computerized information system. So, an e-archive for KPR financing was built at PT Bank Syariah Indonesia using the prototype method. Where the existence of the E-archive system makes it easier for the financing department to manage KPR financing archives for Bank Syariah Indonesia customers and also makes it easier to search and store data, especially data related to financing, which can be done easily.
Evaluation of Antioxidant and Cytotoxicity Activities of Mimosa pudica Linn. Leaf Extract Combined with Silver Nanoparticles (AgNPs) Against Human Colorectal Cancer HCT116 Cell Rahmad Fajral Ilhami; Dian Pertiwi; Dessy Arisanty; Yanti Rahayu
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.1129-1138

Abstract

Colorectal cancer is one of the leading causes of cancer-related morbidity and mortality worldwide, with oxidative stress playing a pivotal role in colorectal carcinogenesis. The limitations of conventional therapies, including systemic toxicity and drug resistance, have driven the exploration of alternative therapeutic agents derived from natural products. Mimosa pudica Linn. leaves are known to contain bioactive compounds with antioxidant and anticancer properties; however, their clinical application is limited by poor biopharmaceutical characteristics. The combination of Mimosa pudica leaf extract with silver nanoparticles (AgNPs) is expected to enhance its biological efficacy through nanotechnology-based drug delivery systems. This study was conducted as an in vitro experimental investigation. Mimosa pudica Linn. leaf extract was prepared using an extraction method and subsequently combined with silver nanoparticles. Antioxidant activity was evaluated using the DPPH assay, with ascorbic acid serving as a positive control. Cytotoxic activity against the human colorectal cancer cell line HCT116 was assessed using the MTT assay to determine cell viability and IC50 values. Statistical analyses were performed to evaluate differences among treatment groups. The results demonstrated that Mimosa pudica Linn. leaf extract exhibited significant antioxidant activity, although it was lower than that of ascorbic acid. In cytotoxicity assays, the leaf extract reduced HCT116 cell viability in a dose-dependent manner. Notably, the combination of Mimosa pudica leaf extract with silver nanoparticles produced a more pronounced cytotoxic effect compared to the extract alone, as indicated by a greater reduction in cell viability and lower IC50 values. In conclusion, Mimosa pudica Linn. leaf extract possesses antioxidant and cytotoxic activities against HCT116 colorectal cancer cells. Its combination with silver nanoparticles enhances cytotoxic potency, highlighting its potential as a nanomedicine-based anticancer candidate for colorectal cancer therapy.
Identification of Cryptosporidium. Sp and Blastocystis. Sp Yanti Rahayu; Rauza Sukma Rita; Ilmiawati Ilmiawati; Nuzulia Irawati
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6627

Abstract

Intestinal protozoan infection is still a major health problem in children, because children are most often in contact with soil as a source of infection and are a significant threat, but are often overlooked to public health until severe or chronic complications because many of them are usually asymptomatic or only manifest mild symptoms. The purpose of this study was to determine the incidence of Cryptosporidium sp, Blastocystis sp infections in school children in Pasir Sebelah, Padang City. This type of research is descriptive categorical, the sample is primary data with a sample size of 66 children using consecutive sampling techniques. Data were collected through direct interviews with caregivers and anthropometric measurements conducted by trained enumerators using standardized tools. This study was analyzed univariately and presented in the form of a frequency distribution table. This study obtained the results of intestinal protozoan infections in children found Cryptosporidium sp 42.4% added and Blastocyctis sp 31.8%. Intestinal protozoan infections were higher in the 7-10 year age group 51.5% and higher in girls 54.5%. The conclusion of this study was that the incidence of intestinal protozoan infections was quite high in children at Elementary School 23 Padang City. Conclusions: these children need special attention, and immediate treatment for infected children and counseling on education and prevention of diseases caused by intestinal protozoa.
The Effect of Wharton’s Jelly Mesenchymal Stem Cells on Nestin Gene Expression in Alzheimer's Rat Models Annita Annita; Arniat Christiani Telaumbanua; Yanti Rahayu; Putri Dafriani; Hendri Panus
Jurnal Kesehatan Saintika Meditory Vol 9, No 1 (2026): Mei 2026
Publisher : STIKES Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jsm.v9i1.30890

Abstract

Alzheimer's disease (AD) is characterized by neurodegeneration and decreased neurogenesis due to neuroinflammation and free radical accumulation. Nestin is an intermediate filament protein that serves as a primary marker for neural progenitor cells in the neurogenesis process. This study aimed to analyze the effect of Wharton’s Jelly Mesenchymal Stem Cells (WJ-MSCs) administration on Nestin gene expression in an Alzheimer's rat model. This experimental study with a posttest-only control group design utilized male white rats (Rattus norvegicus) induced by Aluminum chloride (AlCl3) at a dose of 300 mg/kg BW orally for 5 days to model Alzheimer's pathology. A dose of 1×106 WJ-MSCs was injected intraperitoneally in the treatment group. One month post-therapy, Nestin gene expression from brain tissue was analyzed using quantitative Real-Time Polymerase Chain Reaction (qRT-PCR) and statistically tested with One-Way ANOVA. The results showed a statistically significant difference (p < 0.05), with a significant increase in Nestin gene expression in the WJ-MSCs treated group compared to the positive control group. It is concluded that the administration of WJ-MSCs effectively increases Nestin gene expression, indicating an improvement in the regeneration and neurogenesis processes in the brain tissue of Alzheimer's rat models.
Effect of Mimosa pudica Extract on NF-κB Expression in Blastocystis sp. Inoculated Rats Dzakiyyah Nafies Zirma; Eka Nofita; Nuzulia Irawati; Roza Silvia; Yanti Rahayu
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12339

Abstract

Blastocystis sp. is an intestinal protozoan capable of inducing intestinal inflammation through activation of the Nuclear Factor Kappa B (NF-κB) signaling pathway. Current treatment relies on metronidazole, although its efficacy is limited by variable therapeutic responses and adverse effects. Mimosa pudica contains bioactive compounds with potential antiprotozoal and anti-inflammatory activities. This study aimed to evaluate the effect of Mimosa pudica extract on NF-κB expression in Blastocystis sp.-infected Wistar rats. An experimental post-test control group design was conducted using 30 male Wistar rats randomly assigned to six groups: negative control, positive control, metronidazole (9 mg and 13.9 mg), and Mimosa pudica extract (40 mg and 80 mg). Rats were orally inoculated with 10⁵ Blastocystis sp., followed by treatment. Phytochemical screening and FTIR was performed, and NF-κB expression was analyzed using RT-PCR. Phytochemical analysis confirmed the presence of flavonoids, alkaloids, tannins, and saponins. Administration of Mimosa pudica extract reduced NF-κB expression compared with the positive control. A significant difference in NF-κB expression was observed among the study groups (p = 0.028). These findings suggest that Mimosa pudica extract exhibits antiprotozoal and anti-inflammatory activity and may serve as a potential complementary therapy for blastocystosis through modulation of the NF-κB signaling pathway.
Co-Authors .,, Niken Annita Annita Annita Arniat Christiani Telambanua Arniat Christiani Telaumbanua arniat christiani telaumbanua Corry Handayani Dessy Arisanty Dian Pertiwi Dina Putri Mayaserly Dzakiyyah Nafies Zirma Eka Nofita Eliza Arman Hendri Panus Ibrahim Ibrahim Ilmiawati, Ilmiawati Kurnia Safitri Mardifa Dwi Azhari Marisa - Melanie Sabrina Putri Niken, , Nuzulia Irawati Putri Dafriani Rahmad Fajral Ilhami Rahmi Novita Yusuf Rauza Sukma Rita Roza Silvia Rudi Budi Agung Satria