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All Journal JURNAL REKAYASA SISTEM INDUSTRI JURNAL PHOTON Klinikal Sains (Jurnal Analis Kesehatan) Ensiklopedia of Journal JEDCHEM (JOURNAL EDUCATION AND CHEMISTRY) Human Care Journal Indonesia Berdaya Journal Of Research and Education Chemistry (JREC) Jurnal Katalisator
Alfin Surya
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The AKTIVITAS ANTIDIABETES EKSTRAK KULIT JERING (PITHECELLOBIUM JIRINGA) DENGAN FRAKSI PELARUT METANOL Alfin Surya; Dimas Prada Sumitra; Hesti Marliza; Zaiyar Zaiyar
JURNAL KATALISATOR Vol. 6 No. 1 (2021): jurnal Katalisator Volume 6 No 1, 2021
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1350.877 KB) | DOI: 10.62769/katalisator.v6i1.265

Abstract

ABSTRACT Jering skin is a solid waste that can cause problems if not treated seriously because it pollutes the environment. Based on previous research, the potential possessed by jering skin is very high because it contains flavonoids and polyphenols which are antiseptic, and antioxidant, also has a very toxic toxicity value for shrimp artemia salina, this has the potential as an anticancer. Therefore, this study aims to continue testing other activities, namely by conducting antidiabetic activity tests using the methanol solvent fraction. The method used is to use a Microplate reader or platec reader at a wavelength of 410 nm to determine absorbance, so that with data analysis the Inhibitor Concentration value of 50% (IC50) of sample extracts is inhibited by the α-glucosidase enzyme in hydrolyzing the p-nitrophenyl substrate. -α-D-glucopyranoside (p-NPG) to form glucose. The results of the study obtained an IC50 value of 387,6091 µg/mL. When compared with IC50 values ​​for positive root as a positive control of 0.8135 μg / mL, it is still weak because the root is a pure composition while the Methanol Faction still contains Rough extract still in the fractionation but the dry skin Methanol fraction can be needed as a source to be used as a substitute for further as a joint exploration of antidiabetic in jering skin. Keywords: Jering, Methanol, Antidiabeti, IC50. ABSTRAK Kulit jering merupakan limbah padat yang dapat menimbulkan masalah bila tidak ditangani dengan serius karena mencemari lingkungan. Berdasarkan penelitian sebelumnya, potensi yang dimiliki oleh kulit jering tersebut sangat tinggi karena mengandung senyawa flavonoid dan polifenol yang bersifat antiseptik, dan antioksidan, juga memiliki nilai Toksisitas yang sangat toksit terhadap udang artemia salina hal ini berpotensi sebagai antikanker. Oleh karena itu, penelitian ini bertujuan untuk melanjutkan uji aktivitas lainnya yaitu dengan melakukan uji aktivitas Antidiabetes mengunakan fraksi pelarut metanol. Adapun metode yang digunakan adalah dengan mengunakan Microplate reader atau platec reader pada panjang gelombang 410 nm untuk menentukan absorbansi, sehingga dengan analisis data diperoleh nilai Inhibitor Concentration 50% (IC50) dari ekstrak sampel dalam menghambat kerja enzim α-glukosidase dalam menghidrolisis substrat p-nitrofenil-α-D-glukopiranosida (p-NPG) untuk membentuk glukosa. Hasil dari penelitian diperoleh nilai IC50 adalah sebesar 387,6091 µg/mL. Jika dibandingkan dengan nilai IC50 untuk akarbose sebagai kontrol posistif sebesar 0,8135 µg/mL, memang masih lemah karena akarbose merupakan senyawa murni sedangkan Fraksi Metanol masih berupa ekstrak Kasar walaupun sudah di fraksinasi namun fraksi Metanol kulit jering dapat dikatakan memiliki potensi untuk dilakukan isolasi lebih lanjut sebagai eksplorasi senyawa aktif antidiabetes dalam kulit jering. Kata Kunci : Jering; Metanol; Antidiabetes; IC50.
PERBANDINGAN TOKSISITAS ANTARA EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura) DAN DAUN KAPAS (Gossypium hirsutum) TERHADAP LARVA UDANG (Artemia Salina Leach) DENGAN METODE BSLT (Brine Shrimp Lethality Test) Mega Pratiwi Irawan; Alfin Surya
Klinikal Sains : Jurnal Analis Kesehatan Vol 11 No 1 (2023): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v11i1.3331

Abstract

Gossypium hirsutum cotton is a member of the Malvaceae family, and its seeds and leaves have been widely used for health care. G. hirsutum cotton has secondary metabolites in the form of flavonoids, tannins, saponins and steroids that can provide pharmacological effects. This study aims to determine the comparison of the toxicity between the ethanol extract of cherry leaves (Muntingia calabura) and cotton leaves (Gossypium hirsutum) using the BSLT (Brine Shrimp Lethality Test) method. The extract was made by maceration method using 96% ethanol as solvent. This toxicity test was carried out using 48 hours old Artemia salina L. shrimp larvae. The results of this study were analyzed using a probit table with the LC50 value of the ethanolic extract of cherry leaves, which was 100 ppm, while the LC50 value of the ethanolic extract of cotton leaves was 158 ppm. This indicates that the extract is highly toxic to the mortality test of Artemia salina L. larvae
Upaya peningkatan pengetahuan masyarakat tentang asam urat dan pemeriksaan kesehatan di Kelurahan Lembah Sari, Rumbai Timur Wati, Huda Marlina; Mursyida, Eliya; Susanti, Lasiah; Surya, Alfin; Mardhiyani, Dini
Indonesia Berdaya Vol 5, No 4 (2024)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.2024848

Abstract

Asam urat merupakan salah satu radang sendi yang terjadi karena adanya penumpukan kristal asam urat di jari kaki, pergelangan kaki, lutut, dan paling sering di jempol kaki. Kadar asam urat antara pria dan wanita berbeda, dimana asam urat yang normal pada pria berkisar antara 2,5-7mg/dL dan pada wanita berkisar antara 1,5-6mg/dL. Asam urat yang tinggi dapat diobati dengan obat antiinflamasi non steroid seperti ibuprofen, dan sebagainya. Namun dapat juga dicegah dengan menerapkan pola makan sehat dan pola hidup yang sehat. Pengetahuan masyarakat RT 02 RW 06 Lembah Sari masih minim terhadap asam urat. Pengabdian bertujuan untuk mengedukasi dan mendeteksi dini asam urat. Pengabdian ini dilakukan di RT 02 RW 06 Lembah Sari dengan cara pengisian kuesioner pretest, penyampaian materi secara langsung, dilanjutkan dengan sesi tanya-jawab, dan pengisian kuesioner posttest. Hasil pretest dan posttest terkait pengetahuan asam urat didapatkan adanya peningkatan pengetahuan peserta menjadi baik sebesar 46,2%. Pada pemeriksaan dari 4 orang prempuan didapatkan 50% peserta memiliki kadar asam urat yang tinggi, 1 peserta (25%) rendah, dan 1 peserta (25%) normal.
ANTIOXIDANT ACTIVITY OF THE METHANOL EXTRACT OF TURKEY EGGPLANT (Solanum betaceum Cav.) INVITRO Surya, Alfin; Anggi Wulandari; Hesti Marliza; Zaiyar
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2871

Abstract

Duch Eggplant rich in phytochemicals, such as polyphenols, flavonoids, and carotenoids. Studies have demonstrated the powerful antioxidant activity of these compounds, which can shield body cells from free radical-induced oxidative damage.The aim of this study is to determine the IC50 value of the antioxidant activity present in the skin of the Holland turnip. This study also has implications for human health. Knowing the anti-oxidant skin activity in the inviter allows us to estimate the potential benefits of protecting the body from oxidative damage. 1.1-diphenyl-2-picrylhydrazil (DPPH) is the method employed. This method involves measuring the ability of the extract to neutralize the free radicals in DPPH. We will observe the color changes from purple to yellow and evaluate the free radical's capture capacity based on the degree of color change. The study's findings revealed an IC50 value of 41,019 ppm. The conclusion from the IC50 values obtained is that the methanol extract in the skin of the Dutch teranga has an antioxidant activity that is very strong to counter free radicals. 
Pelatihan Pembuatan Susu Kedelai Kurma “SUDEMA” dalam Upaya Meningkatkan Mikroba Baik Saluran Pencernaan di Kelurahan Lembah Sari, Rumbai Timur Mursyida, Eliya; Surya, Alfin; Widiasari, Santi; Oktariani, Eva; Sidoretno, Wahyu Margi; Wedyawatifitri, Riana Adelaide; Suryandhi, Guntur; Al-Basyari, M. Habib Mifta
Indonesia Berdaya Vol 5, No 2 (2024)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.2024797

Abstract

Indonesia merupakan salah satu Negara yang memiliki sekitar 71 varietas kedelai. Kedelai diketahui memiliki kandungan protein yang hampir sama dengan susu sapi. Protein pada kedelai dapat mempernagruhi komunitas mikroba usus dan dapat juga digunakan sebagai prebiotik. Selain kedelai, kurma juga memiliki banyak manfaat bagi tubuh. Bahkan susu kedelai dan kurma dikombinasi diketahui memiliki manfaat bagi kesehatan. Masyarakat RT 02 RW 06 Lembah Sari masih minim terhadap kombinasi pengolahan susu kedelai kurma. Pengabdian bertujuan untuk melatih masyarakat dalam membuat susu kedelai kurma yang berstandar secara mandiri. Pengabdian ini dilakukan di RT 02 RW 06 Lembah Sari dengan cara melatih secara langsung pembuatan susu kedelai kurma yang disertai penyebaran leaflet tentang cara pembuatan susu kedelai kurma, dilanjutkan dengan sesi tanya-jawab, dan pengisian kuesioner terkait kepuasan masyarakat terhadap pelaksanaan pengabdian. Hasil pengabdian didapatkan bahwa masyarakat sangat antusias dengan pelatihan ini dan dibuktikan dengan data dari pengisian kuesioner yang didapatkan bahwa masyarakat sangat setuju dan setuju dengan diadakannya kegiatan pelatihan ini.
Aktivitas BSLT Fraksi Daun dan Gall Syzygium guineensis: Studi Komparatif Marliza, Hesti; De Nanda Herru, Yoan; Yelmiza, Yelmiza; Surya, Alfin
Journal of Research and Education Chemistry Vol. 7 No. 2 (2025): Oktober
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/jrec.2025.vol7(2).25956

Abstract

This study investigates the Brine Shrimp Lethality Test (BSLT) activity of leaf and gall fractions of Syzygium guineensis, a plant known for its traditional medicinal properties. The objective is to evaluate the cytotoxic potential of these fractions using BSLT, which is a reliable method for assessing toxicity. Leaf and gall samples were extracted using n-hexane, ethyl acetate, and ethanol-water solvents. The cytotoxicity was quantified by determining the LC50 values for each fraction. The results indicated that the leaf fractions exhibited LC50 values of 29.45 ppm (n-hexane), 28.33 ppm (ethyl acetate), and 30.57 ppm (ethanol-water). For the gall fractions, the LC50 values were 27.80 ppm (n-hexane), 26.61 ppm (ethyl acetate), and 24.95 ppm (ethanol-water). All fractions demonstrated significant cytotoxic activity, categorizing them as highly toxic. This study highlights the potential of both leaf and gall fractions of Syzygium guineensis as sources of cytotoxic agents, warranting further investigation for therapeutic applications.  
ADSORPTION STUDY OF LEAD (Pb²⁺) IONS USING CASSAVA PEEL BIOCHAR: EFFECT OF pH AND CONTACT TIME Elfia, Mega; Etriyanto Arman; Eduwin Saputra; Alfin Surya; Yoravika Dwiwibangga; Vicka Andini; Aidil Onasis; Nadya Br Debora
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3484

Abstract

This study evaluates the adsorption performance of NaOH-activated cassava peel biochar (Manihot esculenta Crantz) for the removal of Pb²⁺ ions from aqueous solutions, with particular focus on the effects of solution pH and contact time. Cassava peel biochar was produced via pyrolysis at 180–350 °C and chemically activated using 0.1 M NaOH. Surface functional groups and morphology were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy–Energy Dispersive X-ray (SEM–EDX). Batch adsorption experiments were conducted by varying solution pH (3–8) and contact time (30–120 min), while Pb²⁺ concentrations before and after adsorption were analyzed using Atomic Absorption Spectroscopy (AAS). The results showed that solution pH significantly affected Pb²⁺ adsorption, with the highest adsorption capacity of 9.94 mg/g achieved at pH 5. Contact time also influenced adsorption performance, and the optimum condition was obtained at 90 min, yielding a maximum adsorption capacity of 9.94 mg/g. These findings indicate that NaOH-activated cassava peel biochar exhibits stable and effective Pb²⁺ adsorption under slightly acidic conditions and moderate contact time, highlighting its potential as a low-cost and environmentally friendly adsorbent for Pb²⁺ removal from contaminated wastewater.
YOGHURT FORMULATION FROM RED DRAGON FRUIT AND ACTIVITY TEST AGAINST PATHOGENIC BACTERIA Permata Dewi, Asiska; Musdalifah, Dinda; Surya, Alfin; Shufyani, Fahma
Ensiklopedia of Journal Vol 8, No 1 (2025): Vol. 8 No. 1 Edisi 2 Oktober 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v8i1.3544

Abstract

The dairy product known as yogurt is fermented by lactic acid bacteria. The purpose of this study is to evaluate the properties and antibacterial activity of yogurt at concentrations of 0%, 10%, 20%, and 30% against harmful bacteria, specifically Escherichia coli and Bacillus subtilis. The properties were examined for lactic acid bacteria, viscosity, pH, hedonic value, and organoleptic features. The disk diffusion method was used to test the antibacterial activity. According to the findings of evaluating the yogurt's organoleptic properties, every formula was homogenous, thick, sour-tasting, and pink. The range of the viscosity values is 412 cP to 972 cP. The lactic acid bacteria vary from 6.8x10^9 to 9.0x10^9, and the pH levels fall between 4.26 and 4.42. In contrast, F3 was the most favored formula in the hedonic test. Following that, the average inhibition zones for the antibacterial activity of yogurt against E. coli bacteria at concentrations of 0%, 10%, 20%, and 30% were 7.5 mm, 9.9 mm, 11.2 mm, and 12.2 mm, respectively. In contrast, the inhibition zone diameters against B. subtilis bacteria were 7.4 mm, 9.8 mm, 13.1 mm, and 14.4 mm. A p-value of less than 0.05 indicated a statistically significant difference in antibacterial activity tests. Red dragon fruit yogurt shows antibacterial action against B. subtilis and E. coli, according to the diameter of the inhibition zone that was obtained.. Keywords: yoghurt, red dragon fruit peel, antibacterial activity, E. coli, B. Subtilis
Co-Authors Aidil Onasis Al-Basyari, M. Habib Mifta Anggi Wulandari Dimas Prada Sumitra Eduwin Saputra Etriyanto Arman Hesti Marliza M Syahrul Fiki Mardhiyani, Dini Mega Elfia Mega Pratiwi Irawan, Mega Pratiwi Mursyida, Eliya Musdalifah, Dinda Nadya Br Debora Oktariani, Eva Permata Dewi, Asiska Riko Agustian Rosa Murwindra, Rosa Santi Widiasari, Santi Shufyani, Fahma Sidoretno, Wahyu Margi Suryandhi, Guntur Susanti, Lasiah Vicka Andini Wati, Huda Marlina Wedyawatifitri, Riana Adelaide Yelmiza Yoan De Nanda Herru Yolanda Yolanda Yoravika Dwiwibangga Yulia Yesti Zaiyar Zaiyar zaiyar