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All Journal Jurnal Kedokteran Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA
Eka Arie Yuliyani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology

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Journal : Jurnal Biologi Tropis

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Comparison of Antioxidant Activity Test of Red Dragon Fruit Extract 70% Ethanol Solvent and 96% Ethanol Wiguna, I Made Danuarta; Anak Agung Ayu Niti Wedayani; Restuningdyah, Novia Andansari Putri; Ni Ketut Susilawati; Eka Arie Yuliyani
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8171

Abstract

Super Red Dragon Fruit is known to have various compounds with high antioxidant activity, which are important in preventing or assisting therapies to reduce free radicals in the body. Different types of solvents, including ethanol, can affect the antioxidant levels in dragon fruit compounds. Therefore, it is important to determine the level of ethanol solvent that provides the highest antioxidant activity. This study aims to evaluate the antioxidant activity in red dragon fruit extract using 70% and 96% ethanol solvents and determine whether there is a difference in activity between the two. Using the true experimental method, antioxidant activity in the fruit and skin of red super dragon fruit extracted using two different solvent levels was compared. Based on the shapiro-wilk test which showed a p value of 0.410, it was found that there was no significant difference between the two solvents in terms of antioxidant activity. This result indicates that the antioxidant activity in red dragon fruit extracts with 70% and 96% ethanol solvents has no significant difference.
Effect of Formaldeyde Induction of Histopathological Features of The Lungs of Wistar Rats (Rattus Norvegicus) Yassa, I Wayan Radityakara Wirasena; Anak Agung Ayu Niti Wedayani; Restuningdyah, Novia Andansari Putri; Linda Silvana Sari; Eka Arie Yuliyani
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8173

Abstract

Formaldehyde, a known carcinogen prevalent in everyday environments, poses significant health risks, particularly through inhalation exposure. This study investigates the histopathological changes in the lungs of Wistar rats induced by formaldehyde at doses of 20, 30, and 40 parts per million (ppm) over a three-month period. The research aims to elucidate the onset of dysplasia, a cellular defense mechanism characterized by abnormal epithelial proliferation, as a response to carcinogenic exposure. Utilizing a post-test only control group experimental design, we observed that increased formaldehyde exposure correlates with a heightened severity of dysplasia, with a statistically significant result (p = 0.002). Our findings indicate that varying doses of formaldehyde lead to differential degrees of dysplasia, underscoring the importance of dose-response relationships in assessing the carcinogenic effects of formaldehyde on lung tissue.
Co-Authors Anak Agung Ayu Niti Wedayani Andhito Rafid Chusaeri Baiq Ghassani Kayla Dante Yustisia Dewa Agung Istri Sintha Prajnyaswari Didit Yudhanto Faisal Libryan Fitriatulnisa Gusti Ayu Trisna A Hamsu Kadriyan Hamsu Kadriyan Ika Prasetyaningrum Lalu Muhammad Abiyu Ghafar Linda Silvana Sari Mochammad Alfian Sulaksana Ni Ketut Susilawati Ni Nyoman Geriputri Restuningdyah, Novia Andansari Putri Triana Dyah Cahyawati Wiguna, I Made Danuarta Yassa, I Wayan Radityakara Wirasena