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Restuningdyah, Novia Andansari Putri
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Factors Associated with Compliance to Iron Supplementation Tablet Consumption Among Adolescent Girls in Coastal Area of West Lombok As Shiddiq, Muhammad Hilmy; Lestarini, Ima Arum; Restuningdyah, Novia Andansari Putri
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10188

Abstract

Anemia remains a major health problem among adolescent girls in Indonesia, with significant implications for reproductive health and productivity. Since 2014, the government has implemented an iron supplementation program through schools, yet compliance remains low. This study aimed to analyze the relationship between family support, teacher support, peer support, and socioeconomic status with compliance to iron tablet consumption among adolescent girls at SMAN 1 Lembar. This was an analytical observational study with a cross-sectional design. A total of 84 students were selected using purposive sampling. Data were collected through a validated and reliable online questionnaire and analyzed using the Chi-Square test. The results showed significant associations between teacher support (p<0.05) and peer support (p<0.05) with compliance to iron tablet consumption, while family support and socioeconomic status showed no significant associations (p>0.05). In conclusion, compliance with iron tablet consumption among adolescent girls is more strongly influenced by teacher and peer support than by family or socioeconomic factors. Strengthening school involvement and peer influence may serve as effective strategies to improve adherence and enhance anemia prevention programs.
Hepatic Alteration due to Formaldehyde Exposure on Wistar Rats (Rattus norvegicus) Makbul, Hidayat; Wedayani, Anak Agung Ayu Niti; Punagi, Abdul Qadar; Pieter, Nova Audrey Luetta; Cangara, Muhammad Husni; Lestarini, Ima Arum; Restuningdyah, Novia Andansari Putri
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6455

Abstract

Formaldehyde is a hazardous chemical substance that can be found commonly in the environment which has various effects on cellular functions and could induce the cellular oxidative stress. Oxidative stress has a direct impact on the hepatic condition and could induce the activation of inflammatory mediators, lipid peroxidation, proteosomal degradation, and mitochondrial dysfunction resulting in hepatocyte injury that could be marked by hepatic enzyme elevation and hepatic weight alterations. This research was conducted using 16 Wistar rats (Rattus norvegicus), divided into 4 groups each containing 4 Wistar rats. The first group was the control group, while the other groups were exposed to formaldehyde 10% by inhalation at doses of 20, 30, and 40 ppm formaldehyde persistently for 6 hours daily for about 16 weeks. The result of this study reveals that formaldehyde induction has a significant impact on hepatic weight elevations (p=0.007) and ALT enzyme elevations (p=0.000) in the treatment groups compared with the control group. Collectively, our results provide valuable information on the hazardous effects of formaldehyde inhalation, especially on the liver.
Histopathological Comparison of Nasopharyngeal and Lung Tissue on Wistar Rats Induced with Formaldehyde Abdiman, I Made Tobias; Wedayani, Anak Agung Ayu Niti; Prihatina, Lale Maulin; Restuningdyah, Novia Andansari Putri
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6456

Abstract

Formaldehyde is a toxic substance commonly found in everyday life. Formaldehyde is also a carcinogenic exposure that often occurs in industrial areas. Formaldehyde itself is genotoxic and cytotoxic to tissues that can cause dysplasia to carcinoma. Inhalation of formaldehyde will expose the respiratory tract, which includes the nasopharynx and lung tissue to formaldehyde. Therefore, it is important to know the differences in tissue susceptibility to formaldehyde exposure related to the ability to cause dysplasia and carcinoma. Six Wistar rats were induced with formaldehyde through the inhalation method at a dose of 40 ppm for 16 weeks, and then terminated and subjected to histopathological examination. The degree of dysplasia will be assessed in both tissues, and then compared and tested statistically. The Mann-Whitney U statistical test showed a P value of 0.818, meaning that there was no significant difference between the degree of dysplasia in nasopharyngeal tissue and lung tissue. However, there was a difference in the rate of dysplasia progression between the two tissues, with nasopharyngeal tissue having a faster rate of progression. This difference in the rate of progression is related to the higher amount of formaldehyde deposition in the upper airway.
Comparison of Antioxidant Activity Test of Red Dragon Fruit Extract 70% Ethanol Solvent and 96% Ethanol Wiguna, I Made Danuarta; Anak Agung Ayu Niti Wedayani; Restuningdyah, Novia Andansari Putri; Ni Ketut Susilawati; Eka Arie Yuliyani
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8171

Abstract

Super Red Dragon Fruit is known to have various compounds with high antioxidant activity, which are important in preventing or assisting therapies to reduce free radicals in the body. Different types of solvents, including ethanol, can affect the antioxidant levels in dragon fruit compounds. Therefore, it is important to determine the level of ethanol solvent that provides the highest antioxidant activity. This study aims to evaluate the antioxidant activity in red dragon fruit extract using 70% and 96% ethanol solvents and determine whether there is a difference in activity between the two. Using the true experimental method, antioxidant activity in the fruit and skin of red super dragon fruit extracted using two different solvent levels was compared. Based on the shapiro-wilk test which showed a p value of 0.410, it was found that there was no significant difference between the two solvents in terms of antioxidant activity. This result indicates that the antioxidant activity in red dragon fruit extracts with 70% and 96% ethanol solvents has no significant difference.
Effectiveness of Artificial Wistar Rat Cage Size in Accelerating The Occurrence of Dysplasia in The Process of Formaldehyde Induction Kusuma, I Gusti Ketut Artha Jaya; Anak Agung Ayu Niti Wedayani; Restuningdyah, Novia Andansari Putri; Wiguna, Putu Aditya
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8172

Abstract

Cage is a medium used in placing experimental animals in experimental-based studies to serve as learning instruments related to studying the cause and effect to be investigated. The size of the cage can affect several health factors in experimental animals, such as the social level and stress level of the animal. Formaldehyde is a carcinogenic compound that can cause malignancies if exposed continuously to living things. Therefore, the purpose of this study was to determine whether cage size can affect the degree of dysplasia in Wistar rats induced by 40 ppm formaldehyde. This study is a quantitative study that uses a true experimental research design with post-test only control group design. This study used male Wistar rats (Rattus norvegicus) with a total of 15 rats divided into 3 groups, namely, a small cage group with a size of (27.5 x 21.5 x 9) cm3, a medium cage group with a size of (28 x 22.5 x 10) cm3, and a large cage group with a size of (30 x 24 x 11.5) cm3 with a total of 4 treatment rats (formaldehyde 40 ppm) and 1 control rat (untreated) in each group. The treatment given to rats was carried out 6 hours per day and lasted for 12 weeks until all rats were terminated at the same time. The rats were terminated and histopathological observations were made to assess the degree of dysplasia that occurred. The results of the Kruskal-Wallis statistical test showed a significant relationship (p < 0.05). This study shows that there is a relationship between the size of artificial cages and the degree of dysplasia in Wistar rats induced by 40 ppm formaldehyde.
Effect of Formaldeyde Induction of Histopathological Features of The Lungs of Wistar Rats (Rattus Norvegicus) Yassa, I Wayan Radityakara Wirasena; Anak Agung Ayu Niti Wedayani; Restuningdyah, Novia Andansari Putri; Linda Silvana Sari; Eka Arie Yuliyani
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8173

Abstract

Formaldehyde, a known carcinogen prevalent in everyday environments, poses significant health risks, particularly through inhalation exposure. This study investigates the histopathological changes in the lungs of Wistar rats induced by formaldehyde at doses of 20, 30, and 40 parts per million (ppm) over a three-month period. The research aims to elucidate the onset of dysplasia, a cellular defense mechanism characterized by abnormal epithelial proliferation, as a response to carcinogenic exposure. Utilizing a post-test only control group experimental design, we observed that increased formaldehyde exposure correlates with a heightened severity of dysplasia, with a statistically significant result (p = 0.002). Our findings indicate that varying doses of formaldehyde lead to differential degrees of dysplasia, underscoring the importance of dose-response relationships in assessing the carcinogenic effects of formaldehyde on lung tissue.
Difference In Knowledge About Stunting Among Families with Stunted Children and Non-Stunted Children in Labuhan Haji Village, East Lombok Sesariana, Mayumi Agestia; Djannah, Fathul; Cahyawati, Triana Dyah; Restuningdyah, Novia Andansari Putri
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.8520

Abstract

Stunting is a condition characterized by a child's height or length being below the predicted range for their age, defined by a z-score of ≤2 SD in accordance with WHO child growth criteria. Stunted children suffer from growth retardation caused by malnutrition resulting from inadequate dietary practices or frequent illnesses. SSGI data indicates that East Lombok Regency holds the third highest stunting rates in the NTB province. The knowledge possessed by caregivers correlates with the prevalence of stunting. This study seeks to ascertain the disparity in knowledge between households with stunted children and those with non-stunted children in Labuhan Haji Village, East Lombok. This study is an analytical observational research employing a cross-sectional methodology. 120 participants were chosen using sequential sampling for the data collection. Families with and without stunted children's knowledge of stunting was compared using the Kruskal-Wallis H test on SPSS. The study's findings indicate that families in Labuhan Haji Village, East Lombok, with stunted children and those without do not significantly differ in their understanding of stunting.
Co-Authors Abdiman, I Made Tobias Abdul Qadar Punagi Anak Agung Ayu Niti Wedayani As Shiddiq, Muhammad Hilmy Cahyawati, Triana Dyah Cangara, Husni Eka Arie Yuliyani Fathul Djannah Ima Arum Lestarini Kusuma, I Gusti Ketut Artha Jaya Linda Silvana Sari Makbul, Hidayat Ni Ketut Susilawati Pieter, Nova Audrey Luetta Prihatina, Lale Maulin Putu Aditya Wiguna Sesariana, Mayumi Agestia Wiguna, I Made Danuarta Yassa, I Wayan Radityakara Wirasena