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All Journal Jambura Journal of Health Sciences and Research Journal Health & Science : Gorontalo Journal Health and Science Community Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Quantum Wellness : Jurnal Ilmu Kesehatan Jurnal Sains Farmasi dan Kesehatan Jurnal Praba: Jurnal Rumpun Kesehatan Umum Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Razoki Razoki
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Evaluasi Formulasi Sediaan Floating Mikroenkapsulasi yang Mengandung Ekstrak Etanol Daun Salam (Syzygium Polyanthum) Rahma Yulina Al-Farini; Razoki Razoki; Muhammad Yunus; Hariyadi Dharmawan Syahputra
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 4 No. 1 (2025): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v4i1.4894

Abstract

Ethanol extract of bay leaves is known to have pharmacological activities such as anti-inflammatory, antihypertensive, and antidiabetic. However, its stability and solubility are still challenges. Therefore, a microencapsulation-based delivery system with floating characteristics that can last longer in the stomach was developed. This study aims to evaluate floating microencapsulation preparations containing ethanol extract of bay leaves (Syzygium polyanthum) as an effort to increase the effectiveness and bioavailability of active substances orally. The results showed that microencapsulation had a total floating of more than 4 hours with a water content of 0.47% -2.14%. Stability tests showed no significant changes in physical and chemical characteristics after cycling tests.
Hubungan Tingkat Pengetahuan Dengan Kepatuhan Minum Obat Pada Pasien Tuberkulosis Paru Di Puskesmas PB Selayang II Kota Medan Novriani Erida; Razoki Razoki; July Pranita Nerly Simanjuntak
Jurnal Praba : Jurnal Rumpun Kesehatan Umum Vol. 4 No. 3 (2026): September : Jurnal Praba : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/praba.v4i3.1083

Abstract

Background: Tuberculosis (TB) remains a major public health problem in Indonesia, which ranks among the countries with the highest TB burden globally. Medication adherence during the six-month or longer treatment period is a decisive factor for cure, and patient knowledge is often postulated as one of its determinants. Objective: This study aimed to describe the level of knowledge and medication adherence and to analyze the relationship between the two among pulmonary TB patients at PB Selayang II Community Health Center, Medan City. Methods: This was a cross-sectional analytical study on 36 pulmonary TB outpatients selected by purposive sampling from July to December 2025. Data were collected through a validated 22-item knowledge questionnaire and the Morisky Medication Adherence Scale (MMAS-8). Univariate analysis used frequency distributions; the bivariate association between knowledge and adherence was analyzed using the Fisher-Freeman-Halton exact test because more than 20% of expected cell counts were below five. Results: Most respondents were male (25 ; 69.4%), aged 20–40 years (20 ; 55.6%), had senior high school education (22 ; 61.1%), and were unemployed or retired (13 ; 36.1%). Knowledge was categorized as high in 19 respondents (52.8%) and moderate in 17 (47.2%), with no respondent in the low category. Medication adherence was moderate in 27 respondents (75.0%), low in 7 (19.4%), and high in 2 (5.6%). The Fisher-Freeman-Halton exact test showed no statistically significant association between knowledge and adherence (p = 0.435). Conclusion: Although the majority of pulmonary TB patients at PB Selayang II had moderate to high knowledge, medication adherence remained predominantly at the moderate level, and no statistically significant relationship was found between knowledge and adherence in this sample. Strengthening pill-count monitoring and Directly Observed Treatment (DOT) may still be warranted to improve adherence.
Co-Authors Afriliani Br Sitepu Cut Inssy Mulun Devin Rio Alvaro Elfia Neswita Elfia Neswita Enjelina Br Hutapea Erida Novriani Hariyadi Dharmawan Syahputra July Pranita Nerly Simanjuntak Kevin Wijaya Muhammad Yunus Najwa Aisyah Nerly Juli Pranita Simanjuntak Novriani Erida Rahma Yulina Al-Farini Ricky Martino Roy Indrianto Bangar S Simran Kaur Stefanus Rio Pendamenta Tarigan Veronika Bertua Simanjuntak