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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Abdi Insani Jurnal Mandala Pengabdian Masyarakat AMMA : Jurnal Pengabdian Masyarakat
Niluh Puspita Dewi
Departments Of Pharmacology And Clinical Pharmacy, STIFA Pelita Mas Palu, Central Sulawesi, 94111, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Effect of Purple Leaf (Graptophyllum pictum (L.) Griff) Emulsion on the Histological Parameters of Streptozotocin-Induced Diabetic Rats Niluh Puspita Dewi; Komang Dewik; Syafika Alaydrus; Athia Kurnia Kasim; Nani Astria Polontalo; Wayan Wirawan; Dian Andini; Irma Irma; Imelda Synthia Fatu
Jurnal Penelitian Pendidikan IPA Vol 12 No 1 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i1.14172

Abstract

Damage to vital organs such as the liver, kidneys, and pancreas is a common complication of diabetes mellitus, characterized by chronic hyperglycemia due to pancreatic cell dysfunction. Graptophyllum pictum (purple leaf) is a potential herbal therapy containing bioactive compounds with antioxidant and organ-protective effects. This study aimed to evaluate the effect of purple leaf emulsion on blood glucose levels and the histopathological features of diabetic rats induced by streptozotocin. Rats were divided into six groups: normal control, negative control, positive control (glibenclamide), and three doses of purple leaf emulsion (100, 200, and 300 mg/kg BW). After 28 days of treatment, the emulsion significantly reduced blood glucose levels and improved the histological structures of the liver, kidneys, and pancreas. The 200 mg/kg BW dose was most effective for pancreatic protection, while 300 mg/kg BW provided optimal hepatoprotective and renoprotective effects. These findings highlight the potential of purple leaf as a natural antidiabetic and organ-protective agent.
PEMANFAATAN SIMPLISIA DAUN UNGU SEBAGAI UPAYA PENINGKATAN NILAI TAMBAH EKONOMI MASYARAKAT KELURAHAN LAMBARA, KECAMATAN TAWAELI Niluh Puspita Dewi; Joni Tandi; Syafika Alaydrus; Fadillah Insani
Jurnal Abdi Insani Vol 13 No 5 (2026): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v13i5.3863

Abstract

Lambara Urban Village, Tawaeli District, continues to experience multiple family health challenges, including among residents living in temporary shelters. Preliminary observations identified complaints related to degenerative diseases, particularly diabetes mellitus, indicating the need for community-participatory education on prevention and self-management. Purple leaf (Graptophyllum pictum) is a herbal resource with potential to support diabetes control; however, its utilization in the community remains suboptimal due to limited access to adequate information. This community service program aimed to improve health literacy and practical skills among residents of RT 09, Lambara Urban Village, by introducing simplisia processing to strengthen the use of local resources. The program comprised a preparatory phase (literature review and development of educational materials), followed by outreach delivered through lectures, banner-based media, and leaflet distribution, to address constituents processing and utilization of purple leaf. Outcomes were assessed using pre-test and post-test, complemented by basic health screening and pharmacist-led consultations. The activity was implemented on Tuesday, 13 January 2026, by a team of lecturers and students from STIFA Pelita Mas Palu, involving 27 participants. The results indicated improved participant understanding and encouraged the adoption of healthier lifestyle practices.
Nanogel Formulation of Butterfly Pea Flower Extract (Clitoria ternatea L.) Against Propionibacterium acnes Bacteria Inhibitory Test Niluh Puspita Dewi; Radhika; Magfirah; Indah Kurnia Utami; Yasinta Rakanita; Nur Ramadhani; Nuraisya; Ni Ketut Marlina
Jurnal Penelitian Pendidikan IPA Vol 12 No 6 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i6.15211

Abstract

The chemical components of butterfly pea flowers (Clitoria ternatea L.) have a strong bacterial inhibition zone. The aim of this research is to make nanogels using the active ingredient ethanol extract of butterfly pea flowers and demonstrate the antibacterial activity of nanogels against Propionibacterium acnes bacteria. Because nanogels are more stable, translucent, and have small particle sizes making them efficient in releasing active chemicals and increasing bioavailability, nanogels are used in tropical medicine. Maceration is the extraction technique used. Nanogel of butterfly pea flower ethanol extract (BPFEE) was added to the nanogel formulation at concentrations of F1 (5%), F2 (10%), and F3 (15%). Transmission testing is part of the ideal formula; Other tests for characterization include phytochemical, organoleptic, particle size, pH, adhesion, spreadability and viscosity tests. Next, antibacterial activity was tested against Propionibacterium acnes using the well method. The research results showed that the % transmittance was 84-88%, the organoleptic results were in the form of a gel, color and distinctive aroma, particle size 114.9 – 283.9 mm, pH 5.6 – 6, adhesive power 1.36 – 2.1 seconds, spreadability 4.8-5.6 cm, viscosity 4071 – 3043.75 mPa.S. Telang flower ethanol extract nanogel can inhibit the growth of P. acnes bacteria, namely 8.2-11.7 mm.
Co-Authors Athia Kurnia Kasim Ayu Wulandari Darmayanti Dhitania Ivana Harliwong Dian Andini Fadillah Insani Giska Putri Agustina I Made Dipayana Imelda Synthia Fatu Indah Kurnia Utami Indah Kurnia Utami Irma Irma Joni Tandi Joni Tandi, Joni Komang Dewik Magfira Maramis Mariyani Meike Rachmawati Nadila Nadila Nani Astria Polontalo Ni Ketut Marlina Nur Azizah Nur Ramadhani Nuraisya Putu Intan Radhika Ratna Ika Yususf Rivani Tampang Sri Wahyuni Khalik Sririzqi Muthmainnah Syafika Alaydrus Syafika Alaydrus Syafika Alaydrus Syafika Alaydrus Viani Anggi Wayan Wirawan Yasinta Rakanita Yuliet Yuliet Yunira Wardani