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All Journal JURNAL FARMASIMED (JFM) Mejuajua Health Research Journal of Indonesia
Sudewi
Universitas Tjut Nyak Dhien
Humanities Dentistry Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Pengenalan dan Pencegahan Diabetes Sejak Dini serta Pengecekan Kadar Gula Darah : Pengenalan dan Pencegahan Diabetes Sejak Dini serta Pengecekan Kadar Gula Darah di Mesjid Al-Karim, Desa Sari Laba Jahe, Kecamatan Sibiru-Biru, Kabupaten Deli Serdang Yessi Febriani; Vriezka Mierza; Pravil Mistriyanto Tambunan; Sumardi; Supran Hidayat Sihotang; Sudewi; Nurmala Sari; Salman; alma Handayani Lubis; Kanne Dachi; Mariani Razali
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 1 No. 2 (2021): Desember 2021
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.44 KB) | DOI: 10.52622/mejuajuajabdimas.v1i2.12

Abstract

Menurut angka prevalensi secara global penderita Diabetes mellitus (DM) pada tahun 2017 adalah sebanyak 424,9 juta kasus atau sebesar 8,8% dari keseluruhan penduduk di dunia. Indonesia merupakan negara menempati urutan ke 6 dengan penderita DM sejumlah 10,3 juta. Diabetes mellitus merupakan salah satu penyakit tidak menular yang menyebabkan gangguan metabolisme. Faktor penyebab diabetes mellitus antara lain keturunan, virus yang menimbulkan kerusakan sel beta pankreas, pola makan, kegemukan, pola aktivitas, lingkungan dan kebiasaan tidur. Banyak masyarakat yang belum menyadari penyebab diabetes mellitus adalah dari pola hidup sehari-hari yang salah. Maka perlu di berikan informasi dan edukasi sehingga masyarakat dapat mengenal dan mencegah penyakit diabetes mellitus sejak dini. Sehingga prevalensi terhadap diabetes mellitus akan menurun. Metode penyampaian informasi dan edukasi yang disampaikan yaitu dengan cara persentase. Hasil kegiatan ini meningkatkan pengetahuan masyarakat terhadap penyakit Diabetes mellitus
Antibacterial and Antifungal Activity Test of N-Hexane, Ethyl Acetate, and Ethanol Extracts of Menteng Leaves (Baccaurea racemosa (Reinw.) Mull.Arg.) Against Candida albicans, Staphylococcus aureus, and Escherichia coli Ika Julianti Tambunan; Yessi Febriani; Yufida Laia; Peronika Tampubolon; Sudewi
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/d6fm3g18

Abstract

Background: Infectious diseases caused by Staphylococcus aureus, Escherichia coli, and Candida albicans remain a global health problem. Since prolonged use of synthetic drugs can cause side effects and resistance, natural alternatives are needed. Menteng leaves (Baccaurea racemosa) contain alkaloids, flavonoids, saponins, steroids/terpenoids, and tannins, which have potential antimicrobial properties. Objective: This study aimed to determine the antibacterial and antifungal activities of n-hexane, ethyl acetate, and ethanol extracts of menteng leaves against S. aureus, E. coli, and C. albicans. Method: The research was conducted experimentally through sample collection, simplicia preparation, successive maceration extraction, phytochemical screening, and antimicrobial testing using the agar well diffusion method. Results: From 500 g of simplicia, 10.5 g of n-hexane extract, 11.4 g of ethyl acetate extract, and 18 g of ethanol extract were obtained. Phytochemical screening showed that all three extracts contained different secondary metabolites, with the ethanol extract having the most complete profile. The highest antimicrobial activity was observed in the ethanol extract, with inhibition zones of 18.92 mm against S. aureus, 18.35 mm against E. coli, and 19.58 mm against C. albicans at a concentration of 200 mg/mL. Conclusion: These results indicate that the ethanol extract of menteng leaves has strong potential as a natural antibacterial and antifungal agent.
Formulasi dan Uji Aktivitas Antioksidan Krim Ekstrak Etanol Daun Paku Sisik Naga sebagai Pelembab Yohana Catarina Purba; Syarifah Nadia; Sudewi
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1341

Abstract

Daun paku sisik naga (Pyrrosia piloselloides) merupakan tanaman epifit yang mengandung senyawa flavonoid, alkaloid, saponin, dan tanin yang berpotensi sebagai antioksidan alami. Tujuan: Penelitian ini bertujuan untuk memformulasikan ekstrak etanol daun paku sisik naga ke dalam sediaan krim pelembab serta mengevaluasi mutu fisik, efektivitas kelembaban, dan aktivitas antioksidannya. Metode: Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 96%. Ekstrak diformulasikan menjadi krim pelembab konsentrasi 2%, 2,5%, dan 3%. Evaluasi meliputi uji mutu fisik, uji iritasi, uji kesukaan, uji efektivitas kelembaban menggunakan skin analyzer, serta uji aktivitas antioksidan dengan metode DPPH. Hasil: Ekstrak etanol daun paku sisik naga menghasilkan rendemen 13,6% dan mengandung alkaloid, flavonoid, saponin, tanin, dan terpenoid. Seluruh sediaan krim homogen, stabil, memiliki pH 5,5-6,3, tipe emulsi M/A, dan tidak mengiritasi kulit. Sediaan konsentrasi 3% memberikan kelembaban tertinggi (40,52; kategori normal) dengan persen pemulihan 55,28%. Nilai IC50 ekstrak sebesar 125,13 µg/mL dan sediaan krim 3% sebesar 148,26 µg/mL (kategori antioksidan sedang). Kesimpulan: Ekstrak etanol daun paku sisik naga dapat diformulasikan menjadi krim pelembab yang memenuhi syarat mutu fisik. Sediaan konsentrasi 3% merupakan formula terbaik dengan kemampuan melembabkan kategori normal dan aktivitas antioksidan sedang, serta aman digunakan.
Formulation and Evaluation of an Anti-Acne Toner Preparation Containing Red palm oil (Red palm oil) for Antibacterial Activity Against Propionibacterium acnes Shahira Yasmin; Ernawatty Ginting; Kanne Dachi; Sudewi
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3915

Abstract

Background: Acne is a common skin disorder associated with the growth of Propionibacterium acnes. Red palm oil derived from the fruit contains bioactive compounds with potential antibacterial properties, making it a promising active ingredient for anti-acne toner formulations. Aim: to develop an anti-acne toner containing Red palm oil, evaluate its physical characteristics, and determine its antibacterial activity against Propionibacterium acnes. Methods: This study was an experimental laboratory research using a quantitative approach. Four formulations were prepared, namely F0 (base), F1 (1%), F2 (3%), and F3 (5%) Red palm oil. The formulations were evaluated for organoleptic properties, homogeneity, pH, adhesion, stability using the cycling test, skin irritation, and hedonic acceptance. Antibacterial activity was determined using the disc diffusion method. Results: In conclusion, Red palm oil derived from the fruit can be successfully formulated into an anti-acne toner that meets the required physical evaluation parameters, is stable and safe for use, and exhibits antibacterial activity against Propionibacterium acnes. In conclusion, red palm oil derived from the fruit can be successfully formulated into an anti-acne toner that meets the required physical evaluation parameters, is stable and safe for use, and exhibits antibacterial activity against Propionibacterium acnes.
Co-Authors alma Handayani Lubis Ernawatty Ginting Ika Julianti Tambunan Kanne Dachi Kanne Dachi Mariani Razali Nurmala Sari Peronika Tampubolon Pravil Mistriyanto Tambunan Salman Salman Shahira Yasmin Sumardi Supran Hidayat Sihotang Syarifah Nadia Vriezka Mierza Yessi Febriani Yohana Catarina Purba Yufida Laia